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Cat. No.	Product Name	Target	Signaling Pathways
T24055	FAUC 213 FAUC213,FAUC-213	Dopamine Receptor	GPCR/G Protein; Neuroscience
	FAUC 213 是一种具有口服活性的‘、高度选择性的、可透过血脑屏障的多巴胺 D4受体完全拮抗剂，对 hD4.4的 Ki=2.2 nM。它对 D2和 D3受体的活性较低，对于 hD2、hD3的 Ki 分别为 3.4 μM、5.3 μM。它表现出非典型的抗精神病活性。
T1684	Nitisinone 尼替西农,NTBC,SC0735,Nitisone	Others; Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB; Others
	Nitisinone (SC0735) 是一种 4-羟基苯丙酮酸双加氧酶抑制剂。
T37197	5-HT1A modulator 2 hydrochloride	5-HT Receptor	GPCR/G Protein; Neuroscience
	5-HT1A modulator 2 hydrochloride 是 8-OH-DPAT 的一种衍生物，是5-HT1A 的调节剂，Ki 为 53 nM。
T10168	5-HT1A modulator 1 5-HT1Amodulator1	Phospholipase; Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Metabolism; Neuroscience
	5-HT1A modulator 1 对 5-HT1A、α1-肾上腺素能受体和 D2 受体具有非常高的亲和力（IC50s = 2 nM、10 nM 和 40 nM）。
T62843	5-HT1A antagonist 1
	5-HT1A antagonist 1 (compound 6f) 是一种有效的、选择性的 5-HT1Areceptor 受体拮抗剂 (Ki: 35 nM)。5-HT1A antagonist 1 能够用于研究中枢神经系统疾病。
T27558	HT1042 HT 1042,HT-1042
	HT1042 is an inhibitor of the β5i component of the 20S proteasome complex, it is used to aid in the treatment of inflammatory diseases, autoimmune and hematologic malignancies.
T10872L	CP 96021	5-HT Receptor	GPCR/G Protein; Neuroscience
	CP 96021是一组5-HT1受体和5-HT2受体拮抗剂，具有抗炎特性，是治疗胃肠道和呼吸道哮喘的非自身抗溃疡化合物。
T12207	NEO 376 SPI-376	Dopamine Receptor; 5-HT Receptor; GABA Receptor	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	NEO 376 (SPI-376) 是选择性5-HT1 受体、GABA 受体和多巴胺受体调节剂，可用于精神病的研究。
T8666	Naratriptan	5-HT Receptor	GPCR/G Protein; Neuroscience
	Naratriptan 是一种5-HT1受体选择性激动剂，可作用于偏头疼。
T0203	Sumatriptan succinate 舒马普坦琥珀酸盐,GR 43175,琥珀酸舒马曲坦	5-HT Receptor	GPCR/G Protein; Neuroscience
	Sumatriptan succinate (GR 43175) 是一种5-HT1受体激动剂，可作用于偏头疼的急性治疗。
T21385	Cinitapride 西尼必利,Paxapride,Cidine,cinitapride tartrate,Blaston,Cintapro,Cinmove	5-HT Receptor	GPCR/G Protein; Neuroscience
	Cinitapride (Blaston) 是一种促胃药。它减缓肌肉的活动，以减轻诸如胃酸反流、胃排空延迟和溃疡性消化不良等病症的症状。 Cinitapride 作为 5-HT2 受体的拮抗剂和 5-HT1 和 5-HT4 受体的激动剂。
T22534	8-Hydroxy-DPAT hydrobromide 7-(二丙基氨基)-5,6,7,8-四氢-1-萘酚氢溴酸盐,8-OH-DPAT hydrobromide	5-HT Receptor	GPCR/G Protein; Neuroscience
	8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) 是一种选择性5-HT1A 激动剂，pIC50为 8.19。它对 5-HT1结合位点的亚型有近 1000 倍的选择性。
T23382	Spiroxatrine R 5188	Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Spiroxatrine (R 5188) 是一种选择性和有效性的 5-HT1α 和 α2-adrenergic 双重拮抗剂，具有镇静活性，对5-HT1α、5-HT1 β、5-HT2和多巴胺受体具有抑制作用。Spiroxatrine 可用于研究心血管系统相关疾病。
T1512	Rizatriptan benzoate 苯甲酸利扎曲坦,MK-462 Benzoate	5-HT Receptor	GPCR/G Protein; Neuroscience
	Rizatriptan benzoate (MK-462 Benzoate) 是 5-HT1激动剂，通过选择性结合并激活血清素 (5-HT) 1B 受体和 5-HT 1D 受体，从而缓解偏头痛。
T4978	Sarpogrelate hydrochloride 盐酸沙格雷酯,MCI-9042	5-HT Receptor	GPCR/G Protein; Neuroscience
	Sarpogrelate hydrochloride (MCI-9042) 是一种选择性5-HT2R 拮抗剂，可用于研究与血栓形成有关的血管疾病，对 5-HT2A、5-HT2B 和 5-HT2C 受体的pKi 值分别为 8.52、6.57 和 7.43。
T6602	Naratriptan hydrochloride Naratriptan HCl,Amerge,Naramig,盐酸那拉曲坦,GR-85548A hydrochloride	5-HT Receptor	GPCR/G Protein; Neuroscience
	Naratriptan hydrochloride (GR-85548A hydrochloride) 是一种5-HT1受体激动剂，有抗偏头疼特性。它还可以通过刺激三叉神经系统感觉神经末梢上的 5-HT1D/1B 受体来发挥其作用，从而减少促炎神经肽的释放。
T0162	Quetiapine ICI204636,Quetiapin,喹硫平	Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; AChR; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Quetiapine (ICI204636) 是5-HT 受体激动剂和多巴胺受体拮抗剂，对人5-HT1A 的 pEC50值为 4.77，对人 D2的 pIC50值为 6.33。它用于治疗精神分裂症，以及治疗与 I 型双相情感障碍相关的急性躁狂发作。它对人 D2、HT1、5-HT2A、5-HT2C 受体具有中高等亲和力，pKi 值为 7.25、5.74、7.54和5.55。
T27021	Cinitapride Tartrate
	Cinitapride Tartrate is an agonist of the 5-HT1 and 5-HT4 receptors and is also an antagonist of the 5-HT2 receptors.
T12176	Naratriptan D3 Hydrochloride GR-85548A D3	Others	Others
	Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, is a selective agonist of 5-HT1 receptor subtype.
T60989	Sumatriptan hydrochloride
	Sumatriptan (GR 43175) hydrochloride 可用于研究偏头痛，它是一种口服有效的5-HT1受体激动剂。Sumatriptan hydrochloride 对5-HT1D、5-HT1B 和5-HT1A 受体的 Ki 值分别为 17 nM、27 nM 和 100 nM。
T70257	Avitriptan HCl
	Avitriptan, also known as BMS-180048, is a selective 5-HT1-like receptor agonist. Avitriptan is an effective compound for the treatment of migraine headaches with a prolonged duration of response. Avitriptan Is a Ligand and Agonist of Human Aryl Hydrocarbon Receptor That Induces CYP1A1 in Hepatic and Intestinal Cells.
T23405	Sumatriptan	Others	Others
	Sumatriptan succinate is a selective 5-HT1 receptor agonist with specificity towards 5-HT1D, 5-HT1B, and 5-HT1A.
T4375	Methiothepin maleate Metitepine,甲替平	5-HT Receptor	GPCR/G Protein; Neuroscience
	Methiothepin maleate (Metitepine) 是一种 5-HT1、5-HT6、5-HT7 血清素受体拮抗剂，可阻断血清素自身受体。
T68176	Isamoltane
	Isamoltane is a serotonin 5-HT1 Receptor Antagonist
T22959	m-Chlorophenylbiguanide hydrochloride 1-(3-Chlorophenyl)biguanidehydrochloride,1-(3-氯苯基)双胍	5-HT Receptor	GPCR/G Protein; Neuroscience
	m-Chlorophenylbiguanide hydrochloride 是一种 5-HT3 受体激动剂。它选择性结合 5-HT3(Ki: 0.002 µM) 超过 5-HT1A(Ki: 10 µM) 和 5-HT2(Ki: 10 µM) 受体，但也结合多巴胺转运蛋白上的高亲和力和低亲和力位点( DAT；IC50：在大鼠尾状壳核突触体膜中分别为 0.4 和 34.8 µM）。
T22294	Cinitapride Hydrogen Tartrate	5-HT Receptor	GPCR/G Protein; Neuroscience
	Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an antagonist of the 5-HT2 receptors and as an agonist of the 5-HT1 and 5-HT4 receptors
T78184	MMV009085
	MMV009085是一种针对恶性疟原虫己糖转运体PfHT1的特异性抑制剂，具有潜在的抗疟效果。它同时抑制人葡萄糖转运蛋白，强效抑制葡萄糖吸收（IC50：2.6 μM）及恶性疟原虫3D7株的生长（EC50：1.23±0.04 μM）。
T8136	Perospirone hydrochloride Perospirone HCl,盐酸哌罗匹隆,SM-9018 hydrochloride	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Perospirone hydrochloride (Perospirone HCl) 是非典型的抗精神病剂，可用于精神分裂症的研究。它是可口服的5-HT2A 受体和多巴胺 D2受体的拮抗剂，也是5-HT1A 受体的部分激动剂。
T12480	Pipamperone Floropipamide,McN-JR 3345,酰胺哌啶酮,R 3345	Others; Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience; Others
	Pipamperone (McN-JR 3345) 是5-HT2A 受体和D4受体的高亲和力拮抗剂，也是D2受体的低亲和力拮抗剂，pKi 分别为 8.2、8.0 和 6.7。
T38145	Eltoprazine
	Eltoprazine(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor.IC50 value:Target: 5-HT1A/1B agonist; 5-HT2C antagonistin vitro: The binding of [3H]eltoprazine to whole tissue sections was saturable and revealed an apparent dissociation constant (Kd) of 11 nM. Specific [3H]eltoprazine binding was completely displaced by 5-HT; conversely, unlabelled eltoprazine reduced [3H]5-HT binding to the levels of no...

化合物

Cat.No: T24055

Synonym: FAUC213,FAUC-213

Target: Dopamine Receptor

Cat.No: T1684

Synonym: 尼替西农,NTBC,SC0735,Nitisone

Target: Others, Reactive Oxygen Species

5-HT1A modulator 2 hydrochloride

Cat.No: T37197

Target: 5-HT Receptor

5-HT1A modulator 1

Cat.No: T10168

Synonym: 5-HT1Amodulator1

Target: Phospholipase, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor

5-HT1A antagonist 1

Cat.No: T62843

Cat.No: T27558

Synonym: HT 1042,HT-1042

Cat.No: T10872L

Target: 5-HT Receptor

Cat.No: T12207

Synonym: SPI-376

Target: Dopamine Receptor, 5-HT Receptor, GABA Receptor

Cat.No: T8666

Target: 5-HT Receptor

Sumatriptan succinate

Cat.No: T0203

Synonym: 舒马普坦琥珀酸盐,GR 43175,琥珀酸舒马曲坦

Target: 5-HT Receptor

Cat.No: T21385

Synonym: 西尼必利,Paxapride,Cidine,cinitapride tartrate,Blaston,Cintapro,Cinmove

Target: 5-HT Receptor

8-Hydroxy-DPAT hydrobromide

Cat.No: T22534

Synonym: 7-(二丙基氨基)-5,6,7,8-四氢-1-萘酚氢溴酸盐,8-OH-DPAT hydrobromide

Target: 5-HT Receptor

Cat.No: T23382

Synonym: R 5188

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor

Rizatriptan benzoate

Cat.No: T1512

Synonym: 苯甲酸利扎曲坦,MK-462 Benzoate

Target: 5-HT Receptor

Sarpogrelate hydrochloride

Cat.No: T4978

Synonym: 盐酸沙格雷酯,MCI-9042

Target: 5-HT Receptor

Naratriptan hydrochloride

Cat.No: T6602

Synonym: Naratriptan HCl,Amerge,Naramig,盐酸那拉曲坦,GR-85548A hydrochloride

Target: 5-HT Receptor

Cat.No: T0162

Synonym: ICI204636,Quetiapin,喹硫平

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR, Histamine Receptor

Cinitapride Tartrate

Cat.No: T27021

Naratriptan D3 Hydrochloride

Cat.No: T12176

Synonym: GR-85548A D3

Target: Others

Sumatriptan hydrochloride

Cat.No: T60989

Cat.No: T70257

Cat.No: T23405

Target: Others

Methiothepin maleate

Cat.No: T4375

Synonym: Metitepine,甲替平

Target: 5-HT Receptor

Cat.No: T68176

m-Chlorophenylbiguanide hydrochloride

Cat.No: T22959

Synonym: 1-(3-Chlorophenyl)biguanidehydrochloride,1-(3-氯苯基)双胍

Target: 5-HT Receptor

Cinitapride Hydrogen Tartrate

Cat.No: T22294

Target: 5-HT Receptor

Cat.No: T78184

Perospirone hydrochloride

Cat.No: T8136

Synonym: Perospirone HCl,盐酸哌罗匹隆,SM-9018 hydrochloride

Target: Dopamine Receptor, 5-HT Receptor

Cat.No: T12480

Synonym: Floropipamide,McN-JR 3345,酰胺哌啶酮,R 3345

Target: Others, Dopamine Receptor, 5-HT Receptor

Cat.No: T38145

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