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Search Results for " drosophila "

Targets Recommended: Others Sirtuin

29

抑制剂 & 化合物

6

天然产物

43

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T22026	AGK7	Others; Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	AGK7 是 sirtuin 2 (SIRT2) 抑制剂。它在体外和帕金森病果蝇模型中均能抑制多巴胺能细胞的凋亡。在帕金森病细胞模型中，它改善了 α-突触核蛋白毒性和修饰的包涵体形态
T6111	Selisistat EX-527,司来司他,SEN0014196	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Selisistat (EX-527) 是一种去乙酰化酶 SIRT1 的抑制剂 (IC50=38 nM)，具有有效性和特异性。Selisistat 可以用于神经系统疾病如亨廷顿舞蹈病的研究。
T68110	Moxnidazole
	Moxnidazole 是一种5-硝基咪唑，在微生物试验和果蝇中具有诱变性，诱导小鼠体细胞的遗传改变。
TP1318	Antennapedia Peptide TFA(188842-14-0 free base) Antennapedia Peptide(TFA)	Others	Others
	Antennapedia Peptide TFA (188842-14-0 free base) 是一种 16 个氨基酸的肽，是细胞穿透肽家族的成员，最初来源于果蝇转录因子 Antennapedia 的 60 个氨基酸长的同源域。
T15775	Lotilaner	GABA Receptor; Parasite	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Lotilaner 是杀寄生虫剂，是非竞争性的昆虫GABACl 受体拮抗剂，对果蝇 GABA 受体的IC50值为 23.84 nM。对家犬的 GABAA 无明显作用。
T26684	Auten-99 HBr Auten-99,Auten-99 hydrochloride. Auten-99 HBr,Auten99,Auten 99	Phosphatase	Metabolism
	Auten-99 HBr (Auten-99) 是新型肌管蛋白磷酸酶 Jumpy( MTMR14) 的抑制剂，可通过血脑屏障，具有强大的神经保护作用。
T60127	Chlorantraniliprole Rynaxypyr,Chlorantranilipole,Rynaxpyr	Others	Others
	Chlorantraniliprole (Rynaxypyr) 是一种杀虫剂，能够有效地、选择性地激活鱼尼丁受体 (ryanodine receptor)，对黑腹果蝇和烟芽夜蛾的 ryanodine 受体 EC50 值分别为 40 nM 和 50 nM，对其选择性是对小鼠骨骼肌 2C12 细胞 ryanodine 受体 (EC50，14 μM) 的 300 多倍。
T41087	Penetratin
	Penetratin is a peptide derived from the amphiphilic Drosophila Antennapedia homeodomain.
T28064	ML207 ML 207,LLI01-022,ML-207
	ML207 inhibits lipid storage in Drosophila melanogaster.
T25862	Neomyosuppressin Thr-asp-val-asp-his-val-phe-leu-arg-phenh2,Dromyosuppressin,Neb-MS
	Neomyosuppressin is a myoinhibiting neuropeptide isolated from the grey fleshfly, Neobellieria bullata and Drosophila.
T80399	Andropin
	Andropin为特异于雄性的抗菌肽，源自黑腹果蝇。
T40644	DL-Leucyl-DL-phenylalanine
	DL-Leucyl-DL-phenylalanine, a dipeptide, serves as a substrate for detecting two distinct regions of dipeptidase staining on gels in both Drosophila simulans and Drosophila melanogaster.
T37922	7(Z),11(Z)-Pentacosadiene
	Unsaturated, long-chain hydrocarbons are found on the cuticles of insects and can act as pheromones. In mature Drosophila melanogaster, certain cuticular hydrocarbons are sexually dimorphic: males synthesize 23- and 25-C monoenes and females produce 27- and 29-C dienes. Each of these lipids plays specific roles in regulating male sexual behavior, with dienes stimulating courtship. 7(Z),11(Z)-Pentacosadiene is a 25-C hydrocarbon that is found in low abundance on cuticles of mature Drosophila fema...
T36801	Binucleine 2
	Binucleine 2 is an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki = 0.36 μM), a kinase involved in cell division. It is specific for Drosophila Aurora B kinase, inhibiting it in a dose-dependent manner, with minimal inhibition of human or X. laevis Aurora B kinases at concentrations up to 100 μM. Binucleine 2 induces mitotic and cytokinesis defects in Drosophila Kc167 cells. It prevents Drosophila S2 cells from assembling a contractile ring during cell division ...
TP1840	Antennapedia Peptide
	Antennapedia Peptide is a 16 amino acid peptide corresponding to the region within the Drosophila Antennapedia DNA binding domain that is mapped to be responsible for cellular internalization.
T36188	Ceramide Phosphoethanolamines (bovine)
	Ceramide phosphoethanolamine (CPE) is an analog of sphingomyelin that contains ethanolamine rather than choline as the head group. It is the principal membrane phospholipid in invertebrates such as Drosophila, which lacks sphingomyelin. It is only produced in small amounts in mammalian cells, accounting for approximately 0.02 mol% of total phospholipids in mouse testis and brain. In Drosophila, CPE is biosynthesized by CPE synthase from ceramide and cytidine diphosphate-ethanolamine in the Golgi...
T36230	C2 Ceramide (d14:1/2:0) C2 Ceramide (d14:1/2:0)
	C2 Ceramide (d14:1/2:0) is a bioactive sphingolipid. Dietary administration of C2 ceramide (d14:1/2:0) (100 μM) induces lipotoxic cardiomyopathy via increasing diastolic and systolic diameter as well as reducing fractional shortening and the number of normal cardiac contractile events in Drosophila.
T37923	7(Z)-Pentacosene
	7(Z)-Pentacosene is an unsaturated cuticular hydrocarbon that acts as a contact sex pheromone in fruit flies. In different species and genotypes of Drosophila, it can be found on both males and females. Pentacosene may stimulate copulation either by itself at high concentrations or when combined with other alkenes. Interestingly, the absolute level of pentacosene increases in Drosophila females immediately after copulation.
T38187	6-Aminophenanthridine
	6-Aminophenanthridine is an antiprion agent. It inhibits prion formation in yeast- and mammalian-based screening assays when used alone and, to a greater extent, when used in combination with the α2-adrenergic receptor agonist guanabenz . 6-Aminophenanthridine (300 μM) inhibits protein folding activity of the ribosome (PFAR) by directly competing with protein substrates for the active site and decreases the yield of refolded protein without affecting the refolding rate. It prevents progressive w...
T6664	SecinH3	Apoptosis	Apoptosis
	SecinH3 是cytohesins 的拮抗剂，是选择性细胞粘附素抑制剂。对于hCyh1、hCyh2、mCyh3、hCyh3、果蝇和yGea2-S7的IC50值分别为 5.4 μM、2.4 μM、5.4 μM、5.6 μM、5.6 μM 和 65 μM。
T22552	AD57 (hydrochloride)	Others	Others
	AD57, as polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer blocks the receptor tyrosine kinase RET in Drosophila (IC50: 2 nM). AD57 effectively suppresses tyrosine kinase RET, weakens the activity of numero
T71552	ASC-JM-17
	ASC-JM-17 is an activator of both Nrf1 and Nrf2 proteins. ASC-JM17 acts on Nrf1, Nrf2 and Hsf1 to increase the expression of proteasome subunits, antioxidant enzymes and molecular chaperones. ASC-JM17 ameliorates toxicity of the mutant androgen receptor (AR) responsible for SBMA in cell, fly and mouse models. Knockdown of the Drosophila Nrf1 and Nrf2 ortholog cap ‘n’ collar isoform-C, but not Hsf1, blocks the protective effect of ASC-JM17 on mutant AR-induced eye degeneration in flies.
T37924	7(Z)-Tricosene
	7(Z)-Tricosene is an unsaturated cuticular hydrocarbon that acts as a pheromone in some insects, including Drosophila. While it is present in both sexes of some Drosophila species, it is abundant in males, but not females, of D. melanogaster and D. sechellia. In these species, 7(Z)-tricosene prevents or reduces male courtship behavior and increases female sexual receptivity. It is absent from virgin D. melanogaster females, but is transferred from males to females during mating. In addition, mat...
T60661	CP681301
	CP681301 是CDK5的有效抑制剂，具有抗增殖活性。CP681301 在果蝇中表现出抗肿瘤活性。CP681301 降低神经胶质瘤干细胞中 CD133、OLIG2、SOX2、KI67、pCDK5 蛋白水平的表达。CP681301 减少小鼠胶质瘤异种移植物的自我更新。
T38279	C2-8 C2-8
	C2-8 is an inhibitor of polyglutamine (polyQ) aggregation (IC50s = 25 and 0.05 μM for recombinant HDQ51 and in PC12 cells, respectively). It also inhibits polyQ aggregation in organotypic hippocampal slice cultures isolated from R6/2 transgenic mice and reduces neurodegeneration in a dose-dependent manner in a Drosophila model of Huntington's disease. C2-8 (100 and 200 mg/kg) reduces huntingtin aggregate size, reduces neuronal atrophy, and improves motor performance in a rotarod test in the R6/2...
T71556	MK-1496
	MK1496 is a n orally bioavailable Polo-like kinase 1 (Plk1) inhibitor with potential antineoplastic activity. Polo-like kinase 1 inhibitor MK1496 selectively inhibits Plk1, inducing selective G2/M arrest followed by apoptosis in a variety of tumor cells while causing reversible cell arrest at the G1 and G2 stage without apoptosis in normal cells. Plk1, named after the polo gene of Drosophila melanogaster, is a serine/threonine protein kinase involved in regulating mitotic spindle function in a n...
T80251	Drosocin
	Drosocin为来自黑腹果蝇的具有生物活性的19聚体阳离子抗菌肽。其天然形态含有附着在链内苏氨酸残基上的二糖部分。相较之下，合成的Drosocin同样序列氨基酸构成但不包含二糖，显示出较原生天然化合物低的生物活性。
T36910	PF 04449913 maleate
	Potent Smo antagonist (IC50 = 5 nM). Attenuates the leukemia-initiation potential of AML cells in a serial transplantation mouse model. Also eliminates self-propagation capacity of AML cells. Munchhof et al (2011) Discovery of PF-04449913, a potent and orally bioavailable inhibitor of smoothened. ACS Med.Chem.Lett. 3 106 PMID:24900436 \|Fukushima et al (2016) Small-molecule Hedgehog inhibitor attenuates the leukemia-initiation potential of acute myeloid leukemia cells. Cancer Sci. 107 1422 PMID:2...
T35993	Epitalon (acetate)
	Epitalon is a synthetic tetrapeptide with anti-aging properties.1,2,3,4 Dietary administration of epitalon (0.00001% w/w) reduces levels of lipid peroxidation products in aged D. melanogaster tissue homogenates.1 Epitalon (1 μg/animal) delays age-related estrous shutdown and decreases the frequency of bone marrow cell chromosomal aberrations in female mice.2 It decreases spontaneous mammary gland and ovarian tumor development and metastasis in aged female mice.3 Epitalon also stimulates melatoni...

化合物

Cat.No: T22026

Target: Others, Sirtuin

Cat.No: T6111

Synonym: EX-527,司来司他,SEN0014196

Target: Sirtuin

Cat.No: T68110

Antennapedia Peptide TFA(188842-14-0 free base)

Cat.No: TP1318

Synonym: Antennapedia Peptide(TFA)

Target: Others

Cat.No: T15775

Target: GABA Receptor, Parasite

Cat.No: T26684

Synonym: Auten-99,Auten-99 hydrochloride. Auten-99 HBr,Auten99,Auten 99

Target: Phosphatase

Chlorantraniliprole

Cat.No: T60127

Synonym: Rynaxypyr,Chlorantranilipole,Rynaxpyr

Target: Others

Cat.No: T41087

Cat.No: T28064

Synonym: ML 207,LLI01-022,ML-207

Neomyosuppressin

Cat.No: T25862

Synonym: Thr-asp-val-asp-his-val-phe-leu-arg-phenh2,Dromyosuppressin,Neb-MS

Cat.No: T80399

DL-Leucyl-DL-phenylalanine

Cat.No: T40644

7(Z),11(Z)-Pentacosadiene

Cat.No: T37922

Cat.No: T36801

Antennapedia Peptide

Cat.No: TP1840

Ceramide Phosphoethanolamines (bovine)

Cat.No: T36188

C2 Ceramide (d14:1/2:0)

Cat.No: T36230

Synonym: C2 Ceramide (d14:1/2:0)

7(Z)-Pentacosene

Cat.No: T37923

6-Aminophenanthridine

Cat.No: T38187

Cat.No: T6664

Target: Apoptosis

AD57 (hydrochloride)

Cat.No: T22552

Target: Others

Cat.No: T71552

Cat.No: T37924

Cat.No: T60661

Cat.No: T38279

Synonym: C2-8

Cat.No: T71556

Cat.No: T80251

PF 04449913 maleate

Cat.No: T36910

Epitalon (acetate)

Cat.No: T35993

Cat. No.	Product Name	Target	Signaling Pathways
T4136	Lapachol Bethabarra wood,CI75490,黄钟花醌,Greenhartin,Tecomin	Others; Influenza Virus; Antibacterial; Parasite; Antifungal	Microbiology/Virology; Others
	Lapachol (CI75490) 是从Tabebuia avellanedae 中分离得到的一种萘醌。它具有具有抗菌、抗炎、镇痛、抗肿瘤和抗生素特性。
TN1162	Dibutyl phthalate 1,2-Benzenedicarboxylic acid	Antifection	Microbiology/Virology
	Dibutyl phthalate (1,2-Benzenedicarboxylic acid) 是一种增塑剂，广泛用于工业制造。Dibutyl phthalate可调节 MSH6 巴豆酰化，可诱导诱导氧化损伤和遗传毒性，可破坏果蝇和人体细胞中保守的昼夜节律。
TN1078	Seneciphylline 千里光菲灵碱,千里光非灵	P450; GST	Metabolism; oxidation-reduction
	Seneciphylline 是一种有毒的吡咯烷核生物碱，存在于千里光植物中。它显著增加了环氧水合酶和谷胱甘肽-S-转移酶的特性，但导致细胞色素 P-450 和相关单加氧酶特性的抑制。
T24175	Xanthumin
	Xanthumin is a naturally occurring insect development inhibitor against Drosophila melanogaster. Xanthumin is also an antibacterial compound.
TN5580	Rediocide A
	Rediocide A, an insecticide, can inhibit calcium mobilization in Drosophila G-protein- coupled receptors (GPCR)s other than methuselah, it can induce GPCR desensitization and internalization, and such effects are mediated by the activation of conventional
T36828	9(Z)-Tricosene
	(9Z)-Tricosene is a pheromone released by insects, including D. melanogaster, M. domestica (house fly), and A. mellifera L. (honey bee). In Drosophila, it induces aggregation behavior and is an oviposition guidance cue for females. Due to its aggregation-inducing activity, it is used as a bait pesticide to attract insects to traps. The mechanism of action in Drosophila is the activation of antennal basiconic Or7a receptors. It is also highly produced by honey bees during the waggle dance, which ...

天然产物

Cat.No: T4136

Synonym: Bethabarra wood,CI75490,黄钟花醌,Greenhartin,Tecomin

Target: Others, Influenza Virus, Antibacterial, Parasite, Antifungal

Dibutyl phthalate

Cat.No: TN1162

Synonym: 1,2-Benzenedicarboxylic acid

Target: Antifection

Cat.No: TN1078

Synonym: 千里光菲灵碱,千里光非灵

Target: P450, GST

Cat.No: T24175

Cat.No: TN5580

Cat.No: T36828

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01337	DLL4 Protein, Mouse, Recombinant (His) Dll4,δ4,delta-like 4 (Drosophila),δ-like 4 (Dro...	Mouse	HEK293 Cells
	DLL4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.7 kDa and the accession number is Q9JI71.
TMPY-01915	DLL1 Protein, Mouse, Recombinant (His) Dll1,δ1,delta-like 1 (Drosophila),δ-like 1 (Dro...	Mouse	HEK293 Cells
	DLL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is Q61483.
TMPY-01321	DLL4 Protein, Human, Recombinant (His) hδ2,Delta-like 4,δ-like 4,hdelta2,δ-like 4 (Drosophila	Human	HEK293 Cells
	DLL4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.7 kDa and the accession number is Q9NR61.
TMPY-04803	DLL4 Protein, Human, Recombinant δ-like 4 (Drosophila),delta-like 4 (Drosophila<...	Human	HEK293 Cells
	DLL4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 55 kDa and the accession number is Q9NR61.
TMPY-01379	DLL1 Protein, Human, Recombinant (His) delta-like 1 (Drosophila),DL1,δ,δ-like 1 (Droso...	Human	HEK293 Cells
	DLL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is A0A384P5C6.
TMPY-00776	DLL4 Protein, Human, Recombinant (hFc) δ-like 4 (Drosophila),Delta-like 4,hdelta2,delta-li...	Human	HEK293 Cells
	DLL4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81 kDa and the accession number is Q9NR61.
TMPY-05833	DLL1 Protein, Human, Recombinant (hFc) DELTA1,DL1,delta-like 1 (Drosophila),δ-like 1 (...	Human	HEK293 Cells
	DLL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.82 kDa and the accession number is A0A384P5C6.
TMPY-02123	DLL1 Protein, Rat, Recombinant (His) delta-like 1 (Drosophila),δ-like 1 (Drosophila<...	Rat	HEK293 Cells
	DLL1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.7 kDa and the accession number is A6KB40.
TMPY-05093	DLL4 Protein, Rhesus, Recombinant (His) delta-like 4 (Drosophila),δ-like 4 (Drosophila<...	Rhesus	HEK293 Cells
	DLL4 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.1 kDa and the accession number is XP_001099250.1.
TMPY-00111	OAF Protein, Human, Recombinant (His) OAF homolog (Drosophila),NS5ATP13TP2	Human	HEK293 Cells
	OAF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.4 kDa and the accession number is Q86UD1.
TMPY-04098	DLL1 Protein, Rat, Recombinant (hFc) δ-like 1 (Drosophila),delta-like 1 (Drosophila<...	Rat	HEK293 Cells
	DLL1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.4 kDa and the accession number is A6KB40.
TMPY-03241	KIRREL3 Protein, Rat, Recombinant (His) kin of IRRE like 3 (Drosophila)	Rat	HEK293 Cells
	KIRREL3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.4 kDa and the accession number is Q09GS6.
TMPY-05796	DLL4 Protein, Mouse, Recombinant (mFc) δ4,Dll4,delta-like 4 (Drosophila),δ-like 4 (Dro...	Mouse	HEK293 Cells
	DLL4 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 80.61 kDa and the accession number is Q9JI71.
TMPY-03457	ERH Protein, Human, Recombinant (His) DROER,enhancer of rudimentary homolog (Drosophila)	Human	E. coli
	ERH(enhancer of rudimentary homolog) belongs to the E(R) family. It is expressed in all tissues examined. The monomeric structure of ERH comprises a single domain consisting of three α-helices and four β-strands, which is a novel fold. In the crystal structure, ERH assumes a dimeric structure, through interactions between the β-sheet regions. The formation of an ERH dimer is consistent with the results of analytical ultracentrifugation. ERH may have a role in the cell cycle. The Drosophil...
TMPY-01015	KIRREL Protein, Mouse, Recombinant (His) 6720469N11Rik,Kirrel1,kin of IRRE like (Drosophila)...	Mouse	HEK293 Cells
	KIRREL Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.8 kDa and the accession number is Q80W68-1.
TMPH-00504	Bursicon Protein, Drosophila melanogaster, Recombinant (GST) Bursicon,Cuticle-tanning hormone,Bursicon subunit alpha,burs...	Fruit fly	E. coli
	Final heterodimeric neurohormone released at the end of the molting cycle, involved in the sclerotization (tanning) of the insect cuticle, melanization and wing spreading. Heterodimer specifically activates the G protein-coupled receptor rk. Bursicon Protein, Drosophila melanogaster, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 42.5 kDa and the accession number is Q9VD83.
TMPY-04131	KIRREL Protein, Human, Recombinant (hFc) kin of IRRE like (Drosophila),NEPH1	Human	HEK293 Cells
	KIRREL Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 78.8 kDa and the accession number is Q96J84-1.
TMPY-06876	DLL4 Protein, Human, Recombinant (His & Avi), Biotinylated hδ2,δ-like 4,Delta-like 4,δ-like 4 (Drosophila),del...	Human	HEK293 Cells
	DLL4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 57.55 kDa and the accession number is NP_061947.1.
TMPY-03255	ROBO2 Protein, Human, Recombinant (His) SAX3,roundabout homolog 2 (Drosophila),ROBO2,KIAA15...	Human	HEK293 Cells
	ROBO2 belongs to the ROBO family. Members of the ROBO family are a group of highly conserved transmembrane glycoproteins that make up a small subgroup of the immunoglobulin (Ig) superfamily. They are best known for their roles as receptors for the Slit family of repellent axon guidance cues. In structure, ROBOs are characterized by five C2-type Ig-like repeats, three fibronectin type III domains, a transmembrane region, and an intracellular domain with three (ROBO3) or four (ROBO1, 2) CC (conser...
TMPH-00505	RPB1 Protein, Drosophila melanogaster, Recombinant (His)	Fruit fly	P. pastoris (Yeast)
	RPB1 Protein, Drosophila melanogaster, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 33.6 kDa and the accession number is P04052.
TMPH-00506	NXF2 Protein, Drosophila melanogaster, Recombinant (His)	Fruit fly	Baculovirus Insect Cells
	NXF2 Protein, Drosophila melanogaster, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 33.7 kDa and the accession number is Q9VV73.
TMPY-02631	ROBO4 Protein, Mouse, Recombinant (His) AI593217,roundabout, axon guidance receptor, homolog 4 (...	Mouse	HEK293 Cells
	ROBO4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.6 kDa and the accession number is A0A0R4J197.
TMPY-00003	KIRREL2 Protein, Human, Recombinant (hFc) kin of IRRE like 2 (Drosophila),NLG1,NEPH3,FILTRIN	Human	HEK293 Cells
	KIRREL2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 77.6 kDa and the accession number is Q6UWL6-1.
TMPY-04238	KIRREL2 Protein, Human, Recombinant (His) FILTRIN,NLG1,kin of IRRE like 2 (Drosophila),NEPH3	Human	HEK293 Cells
	KIRREL2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.3 kDa and the accession number is Q6UWL6-2.
TMPY-01557	MAGOH Protein, Human, Recombinant (His) MAGOHA,MAGOH1,mago-nashi homolog, proliferation-associated (...	Human	E. coli
	MAGOH (Mago Homolog, Exon Junction Complex Subunit) is a Protein Coding gene. MAGOH is the human homolog of Drosophila mago nashi, a protein that is required for normal germplasm development in the Drosophila embryo. In mammals, mRNA expression is not limited to the germplasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. The exon junction complex (EJCs) are deposited on messenger RNAs (mRNAs) during splicing and their core consi...
TMPH-00508	Pro-resilin Protein, Drosophila melanogaster, Recombinant (His & Myc)	Fruit fly	E. coli
	Plays a central role in insect flight by providing low stiffness, high strain and efficient energy storage.
TMPY-01657	SUV420H2 Protein, Human, Recombinant (His & GST) suppressor of variegation 4-20 homolog 2 (Drosophila	Human	E. coli
	Histone-lysine N-methyltransferase SUV42H2, also known as Suppressor of variegation 4-2 homolog 2, Su(var)4-2 homolog 2, Lysine N-methyltransferase 5C, SUV42H2 and KMT5C, is nucleus protein that belongs to the histone-lysine methyltransferase family and Suvar4-2 subfamily. SUV42H2 is a histone methyltransferase that specifically trimethylates 'Lys-2' of histone H4. H4 'Lys-2' trimethylation represents a specific tag for epigenetic transcriptional repression. SUV42H2 mainly functions in pericentr...
TMPY-02020	ROBO4 Protein, Human, Recombinant (His) roundabout, axon guidance receptor, homolog 4 (Drosophil...	Human	HEK293 Cells
	ROBO4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49 kDa and the accession number is Q8WZ75-1.
TMPH-00507	PGRP-SC2 Protein, Drosophila melanogaster, Recombinant (His & Myc)	Fruit fly	E. coli
	N-acetylmuramyl-L-alanine amidase involved in innate immunity by degrading bacterial peptidoglycans (PGN). Probably plays a scavenger role by digesting biologically active PGN into biologically inactive fragments. Has no direct bacteriolytic activity. PGRP-SC2 Protein, Drosophila melanogaster, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 25.2 kDa and the accession number is Q9V4X2.
TMPY-02089	KIRREL3 Protein, Mouse, Recombinant (His) SST4,kin of IRRE like 3 (Drosophila),NEPH2,2900036G...	Mouse	HEK293 Cells
	KIRREL3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.5 kDa and the accession number is Q8BR86-1.
TMPY-02807	TWSG1 Protein, Mouse, Recombinant (His) Twg,Twsg1,9030422N06Rik,AW552143,twisted gastrulation homolo...	Mouse	HEK293 Cells
	TWSG1 belongs to the twisted gastrulation protein family. TWSG1 from different species are functionally equivalent. In contrast to Drosophila where TWSG1 expression is limited to early embryos, expression of TWSG1 is found throughout mouse and human development. Mutations in the TWSG1 gene cause at least some of the cells on the dorsal half of the embryo to adopt more ventral cell fates. This is thought to involve gradients of the signaling molecule decapentaplegic. TWSG1 may function as a bone ...
TMPH-00509	Protein-L-isoaspartate Protein, Drosophila melanogaster, Recombinant (His & Myc)	Fruit fly	E. coli
	Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in aging peptides and proteins. Protein-L-isoaspartate Protein, Drosophila melanogaster, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.0 kDa and the accession number is Q27869.
TMPH-00503	60S ribosomal protein L10 Protein, Drosophila melanogaster, Recombinant (His) QM protein homolog,Large ribosomal subunit protein uL16,dQM,...	Fruit fly	E. coli
	60S ribosomal protein L10 Protein, Drosophila melanogaster, Recombinant (His) is expressed in E. coli.
TMPY-02904	TLR4 Protein, Human, Recombinant (His) TLR-4,TOLL,toll-like receptor 4,ARMD10,TLR4,CD284	Human	Baculovirus Insect Cells
	TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. TLR4 is most abundantly expressed...
TMPK-01395	TENM2 Protein, Human, Recombinant (His) Ten-m2,KIAA1127,Teneurin-2,TNM2,ODZ2,Tenascin-M2,Ten-2	Human	HEK293 Cells
	Teneurin-2 is a member of a novel family of transmembrane proteins characterized to date in fish, birds, mammals, and Drosophila (e.g., the pair-rule gene product Ten-m). Teneurin-2, a vertebrate homologue of the Drosophila pair-rule gene ten-m/odz, is revealed to be a membrane-bound transcription regulator. In the nucleus, the intracellular domain of teneurin-2 colocalizes with promyelocytic leukemia (PML) protein in nuclear bodies implicated in transcription control.
TMPY-03442	MOB4A/MOB1B Protein, Human, Recombinant (GST) MOB kinase activator 1B,MOBKL1A,MATS2,MOB4A	Human	E. coli
	MST1 and MST2 are the mammalian Ste2-related protein kinases most closely related to Drosophila Hippo, a major regulator of cell proliferation and survival during development. Overexpression of MST1 or MST2 in mammalian cells is proapoptotic. MST1 and MST2 activity increase during mitosis, especially in nocodazole-arrested mitotic cells, where these kinases exhibit an increase in both abundance and activation. MST1 and MST2 also can be activated nonphysiologically by okadaic acid or H2O2. The MO...
TMPY-02837	GPR114 Protein, Human, Recombinant (hFc) PGR27,GPR114	Human	HEK293 Cells
	GPR114 belongs to the G-protein coupled receptor 2 family. Members of this family share a common molecular architecture which consists of seven transmembrane domains, three extracellular loops, three intracellular loops, an amino-terminal extracellular domain, and an intracellular carboxyl terminus. It is thought that light acts as the activating stimulus of a G-protein-coupled receptor (GPCR). GPCRs are expected to have a molecular function (G-protein coupled receptor activity) and to localize ...
TMPY-02847	Moesin Protein, Human, Recombinant (aa 1-346, His) moesin,HEL70	Human	E. coli
	Moesin is a member of the ERM family which includes ezrin and radixin. ERM proteins, highly related members of the larger protein 4.1 superfamily, can exist in an active or inactive conformation. It seems that ERM proteins function as cross-linkers between plasma membranes and actin-based cytoskeletons. The sole Drosophila ERM protein, moesin, functions to promote cortical actin assembly and apical-basal polarity. As a result, cells lacking moesin lose epithelial characteristics and adopt invasi...
TMPY-04458	TRIB2 Protein, Human, Recombinant (His & GST) TRIBBLE,tribbles pseudokinase 2,TRIB2,C5FW,FLJ57420,GS3955,T...	Human	Baculovirus Insect Cells
	Tribbles homolog 2, also known as TRB-2, and Trib2, is a member of the protein kinase superfamily and Tribbles subfamily (Trib1, Trib2, Trib3). The identification of tribbles as regulators of signal processing systems and physiological processes, including development, together with their potential involvement in diabetes and cancer, has generated considerable interest in these proteins. Tribbles have been reported to regulate the activation of some intracellular signalling pathways with roles e...
TMPY-02957	DYDC2 Protein, Human, Recombinant (GST) DPY30 domain containing 2	Human	E. coli
	DPY30 domain containing 2 belongs to the dpy-30 family. Dumpy-30 family members act as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. MTF-1 plays a key role in transition metal detoxification and homeostasis. It binds to metal response elements (MREs). Two candidate dMTF-1 interactors are related to the small regulatory protein Dumpy-30 (Dpy-30) of the worm C. elegans. Dpy-30 is the founding member of a protein family inv...
TMPY-01661	METTL1 Protein, Human, Recombinant (His) methyltransferase like 1,TRMT8,TRM8,YDL201w,C12orf1	Human	E. coli
	tRNA (guanine-N(7)-)-methyltransferase, also known as Methyltransferase-like protein 1, tRNA (m7G46)-methyltransferase and METTL1, is a nucleus protein that belongs to the methyltransferase superfamily and TrmB family. METTL1 gene has been identified by its sequence similarity to the yeast ORF YDL21w. The human cDNA and the genomic structure of METTL1 have been analyzed. The transcript contains 1292 nucleotides and codes for a protein of 276 amino acids. The METTL1 gene product shows high sequen...
TMPY-02289	CIB2 Protein, Human, Recombinant (His) DFNB48,calcium and integrin binding family member 2,USH1J,KI...	Human	E. coli
	Calcium and integrin-binding protein 2 (CIB2) belongs to a protein family with four known members, CIB1 through CIB4, which are characterized by multiple calcium-binding EF-hand domains. Sensorineural hearing loss is genetically heterogeneous. The mutations in CIB2, which encodes a calcium- and integrin-binding protein, are associated with nonsyndromic deafness (DFNB48) and Usher syndrome type 1J (USH1J). Furthermore, in zebrafish and Drosophila melanogaster, CIB2 is essential for the function a...
TMPY-01958	RhoA Protein, Human, Recombinant (His) ras homolog family member A,ARHA,RHO12,RHOH12,ARH12	Human	Baculovirus Insect Cells
	Transforming protein RhoA, also known as Rho cDNA clone 12, Ras homolog gene family member A, RHOA and ARH12, is a cell membrane and cytoplasm protein that belongs to the small GTPase superfamily and Rho family. The Rho family of small GTPases plays a key role in the dynamic regulation of the actin cytoskeleton that underlies various important cellular functions such as shape changes, migration, and polarity. RHOA / ARH12 is part of a larger family of related proteins known as the Ras superfamil...

重组蛋白

DLL4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01337

Species: Mouse

Expression System: HEK293 Cells

DLL1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01915

Species: Mouse

Expression System: HEK293 Cells

DLL4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01321

Species: Human

Expression System: HEK293 Cells

DLL4 Protein, Human, Recombinant

Cat.No: TMPY-04803

Species: Human

Expression System: HEK293 Cells

DLL1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01379

Species: Human

Expression System: HEK293 Cells

DLL4 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00776

Species: Human

Expression System: HEK293 Cells

DLL1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05833

Species: Human

Expression System: HEK293 Cells

DLL1 Protein, Rat, Recombinant (His)

Cat.No: TMPY-02123

Species: Rat

Expression System: HEK293 Cells

DLL4 Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-05093

Species: Rhesus

Expression System: HEK293 Cells

OAF Protein, Human, Recombinant (His)

Cat.No: TMPY-00111

Species: Human

Expression System: HEK293 Cells

DLL1 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-04098

Species: Rat

Expression System: HEK293 Cells

KIRREL3 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03241

Species: Rat

Expression System: HEK293 Cells

DLL4 Protein, Mouse, Recombinant (mFc)

Cat.No: TMPY-05796

Species: Mouse

Expression System: HEK293 Cells

ERH Protein, Human, Recombinant (His)

Cat.No: TMPY-03457

Species: Human

Expression System: E. coli

KIRREL Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01015

Species: Mouse

Expression System: HEK293 Cells

Bursicon Protein, Drosophila melanogaster, Recombinant (GST)

Cat.No: TMPH-00504

Species: Fruit fly

Expression System: E. coli

KIRREL Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04131

Species: Human

Expression System: HEK293 Cells

DLL4 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06876

Species: Human

Expression System: HEK293 Cells

ROBO2 Protein, Human, Recombinant (His)

Cat.No: TMPY-03255

Species: Human

Expression System: HEK293 Cells

RPB1 Protein, Drosophila melanogaster, Recombinant (His)

Cat.No: TMPH-00505

Species: Fruit fly

Expression System: P. pastoris (Yeast)

NXF2 Protein, Drosophila melanogaster, Recombinant (His)

Cat.No: TMPH-00506

Species: Fruit fly

Expression System: Baculovirus Insect Cells

ROBO4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02631

Species: Mouse

Expression System: HEK293 Cells

KIRREL2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00003

Species: Human

Expression System: HEK293 Cells

KIRREL2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04238

Species: Human

Expression System: HEK293 Cells

MAGOH Protein, Human, Recombinant (His)

Cat.No: TMPY-01557

Species: Human

Expression System: E. coli

Pro-resilin Protein, Drosophila melanogaster, Recombinant (His & Myc)

Cat.No: TMPH-00508

Species: Fruit fly

Expression System: E. coli

SUV420H2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-01657

Species: Human

Expression System: E. coli

ROBO4 Protein, Human, Recombinant (His)

Cat.No: TMPY-02020

Species: Human

Expression System: HEK293 Cells

PGRP-SC2 Protein, Drosophila melanogaster, Recombinant (His & Myc)

Cat.No: TMPH-00507

Species: Fruit fly

Expression System: E. coli

KIRREL3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02089

Species: Mouse

Expression System: HEK293 Cells

TWSG1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02807

Species: Mouse

Expression System: HEK293 Cells

Protein-L-isoaspartate Protein, Drosophila melanogaster, Recombinant (His & Myc)

Cat.No: TMPH-00509

Species: Fruit fly

Expression System: E. coli

60S ribosomal protein L10 Protein, Drosophila melanogaster, Recombinant (His)

Cat.No: TMPH-00503

Species: Fruit fly

Expression System: E. coli

TLR4 Protein, Human, Recombinant (His)

Cat.No: TMPY-02904

Species: Human

Expression System: Baculovirus Insect Cells

TENM2 Protein, Human, Recombinant (His)

Cat.No: TMPK-01395

Species: Human

Expression System: HEK293 Cells

MOB4A/MOB1B Protein, Human, Recombinant (GST)

Cat.No: TMPY-03442

Species: Human

Expression System: E. coli

GPR114 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02837

Species: Human

Expression System: HEK293 Cells

Moesin Protein, Human, Recombinant (aa 1-346, His)

Cat.No: TMPY-02847

Species: Human

Expression System: E. coli

TRIB2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04458

Species: Human

Expression System: Baculovirus Insect Cells

DYDC2 Protein, Human, Recombinant (GST)

Cat.No: TMPY-02957

Species: Human

Expression System: E. coli

METTL1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01661

Species: Human

Expression System: E. coli

CIB2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02289

Species: Human

Expression System: E. coli

RhoA Protein, Human, Recombinant (His)

Cat.No: TMPY-01958

Species: Human

Expression System: Baculovirus Insect Cells

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