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Search Results for " cia "

Targets Recommended: Microtubule Associated AAK1 (AP2 associated kinase 1) Gamma-secretase

56

抑制剂 & 化合物

10

天然产物

12

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T71534L	CIA-1 (Free base) CIA-1(Free base）	Gamma-secretase	Neuroscience; Proteases/Proteasome; Stem Cells
	CIA-1 (Free base) 是一种核受体 COUP-TFII 抑制剂，在前列腺癌细胞系中IC50 值在 1.2 μM 到 7.6 μM 之间。CIA-1 (Free base) 在前列腺癌异种移植小鼠模型中抑制肿瘤生长。
T71534	CIA-1 hcl(452087-38-6 Free base)	Gamma-secretase	Neuroscience; Proteases/Proteasome; Stem Cells
	CIA-1对核受体COUP-TFII 具有抑制作用，在前列腺癌细胞系中IC50范围从1.2μM 到7.6μM 之间。CIA-1在体外抑制多种前列腺癌细胞系的生长并抑制COUP-TFII 活性以调节其靶基因。CIA-1在体内对前列腺癌异种移植小鼠模型中的肿瘤生长具有抑制作用。
T2057	BVT 2733	Dehydrogenase	Metabolism
	BVT 2733 是具有口服活性的、强效的、非甾体类11β-HSD1选择性抑制剂。它对小鼠 11β-HSD1 酶的作用 (IC50:96 nM) 比对人 11β-HSD1 酶 (IC50:3341 nM) 的作用强。它对关节炎和肥胖相关疾病具有潜在的研究价值。
T4195	Betahistine PT 9 base,倍他司汀,Vasomotal,Serc base	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Betahistine (Vasomotal) 是可口服的组胺 H1 受体激动剂和 H3 受体的拮抗剂，可用作血管扩张剂，用于类风湿性关节炎的研究。
T0246	Betahistine dihydrochloride PT-9,Betahistine 2HCl,盐酸倍他司汀	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Betahistine dihydrochloride (Betahistine 2HCl) 是可口服的组胺 H1 受体激动剂和 H3 受体的拮抗剂，可用作血管扩张剂，用于类风湿性关节炎的研究。
T2125	Trametinib GSK1120212,曲美替尼,JTP-74057	Apoptosis; MEK; Autophagy	Apoptosis; Autophagy; MAPK
	Trametinib (GSK1120212) 是一种 MEK 抑制剂，抑制 MEK1 和 MEK2 (IC50=0.7/0.9 nM)，具有 ATP 非竞争性和口服活性。Trametinib 可以激活自噬，诱导凋亡。
T72006	DCAI Hydrochloride
	DCAI hydrochloride is an inhibitor of nucleotide exchange and nucleotide release, by binding to the pocket adjacent to the Ras-SOS interface.
T5857	Trametinib (DMSO solvate) Trametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfoxide,JTP-74057 (DMSO solvate)	Apoptosis; MEK	Apoptosis; MAPK
	Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) 是一种口服有效的 MEK 抑制剂，抑制 MEK1 和 MEK2 的 IC50分别为 2 nM。它还能激活自噬，诱导凋亡。
T21649L	GnRH Associated Peptide (GAP) (1-13), human Acetate GnRH Associated Peptide (GAP) (1-13), human Acetate (100111-07-7 Free base)	Others	Others
	GnRH Associated Peptide (GAP) (1-13), human Acetate 被发现是催乳素分泌的有效抑制剂并刺激促性腺激素的释放。用对应于 GAP 序列的肽进行主动免疫导致催乳素分泌大大增加。
T68043	Ciamexon Ciamexone,BM 41332,BM41332,BM-41332	Others	Others
	Ciamexon (Ciamexone) 是一种新型的免疫调节剂，在自身免疫性疾病的实验模型中具有良好的效果，几乎没有显示出细胞毒性。Ciamexon 可用于研究内分泌眼病和糖尿病，在短时间给药后眼科疾病得到轻微改善。
T17870	cIAP1 ligand 1 E3 ligase Ligand 12	Others	Others
	cIAP1 ligand 1 (E3 ligase Ligand 12) 是基于 LCL161 衍生物的细胞凋亡蛋白配体，可募集 IAP 泛素连接酶以降解靶蛋白，可用于和雄激素受体配体偶联开发蛋白降解剂，可用于研究前列腺癌。
T17886	cIAP1 Ligand-Linker Conjugates 15 hydrochloride E3 ligase Ligand-Linker Conjugates 34 hydrochloride	Others	Others
	cIAP1 Ligand-Linker Conjugates 15 hydrochloride is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is useful in the development of SNIPERs[1].
T17894	cIAP1 Ligand-Linker Conjugates 3 E3 ligase Ligand-Linker Conjugates 40	Others	Others
	cIAP1 Ligand-Linker Conjugates 3 are chemical compounds comprising an IAP ligand designed specifically for the E3 ubiquitin ligase and a PROTAC linker. These conjugates, denoted as cIAP1 Ligand-Linker Conjugates 3, find utility in the design of SNIPERs, short for Specific and Non-genetic IAP-dependent Protein Erasers [1].
T64302	XIAP/cIAP1 antagonist-1
	XIAP/cIAP1 antagonist-1 是一种有效的、口服具有活力的 XIAP/cIAP1 拮抗剂，能够作用于 XIAP (EC50: 5.1 nM) 和 cIAP1 (EC50: 0.32 nM)。XIAP/cIAP1 antagonist-1 能够剂量依赖性地抑制体内肿瘤生长。
T17869	cIAP1 ligand 2 E3 ligase Ligand 11	Others	Others
	cIAP1 ligand 2, a derivative of LCL161, is an IAP ligand that can be connected to the ABL ligand for protein via a linker, resulting in the formation of SNIPER.
T25248	Cianopramine Ro 112465,Ro-112465,Ro112465
	Cianopramine is a tricyclic antidepressant and a potent neuronal serotonin (5-HT) uptake inhibitor in animals.
T17895	cIAP1 Ligand-Linker Conjugates 1 E3 ligase Ligand-Linker Conjugates 41	Others	Others
	cIAP1 Ligand-Linker Conjugates 1 is composed of an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 1, is particularly useful in the development of SNIPERs[1].
T39609	cIAP1 Ligand-Linker Conjugates 16 cIAP1 Ligand-Linker Conjugates 16
	cIAP1 Ligand-Linker Conjugates 16 refers to a specific type of ligase ligand-linker conjugate, possessing the ability to engage with E3 ligases, which finds application in the synthesis of PROTACs.
T29390	m-Ciaamp 3-Carboxyphenyl((N-((4-iodophenyl)acetyl)amino)methyl)phosphonate
	3-Carboxyphenyl((N-((4-iodophenyl)acetyl)amino)methyl)phosphonate is a bioactive chemical.
T17884	cIAP1 Ligand-Linker Conjugates 11 Hydrochloride E3 ligase Ligand-Linker Conjugates 33 Hydrochloride	Others	Others
	cIAP1 Ligand-Linker Conjugates 11 Hydrochloride is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. It is primarily utilized in the development of SNIPERs, a molecular tool for targeted protein degradation[1].
T17898	cIAP1 Ligand-Linker Conjugates 7 E3 ligase Ligand-Linker Conjugates 44	Others	Others
	cIAP1 Ligand-Linker Conjugates 7 is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a PROTAC linker. It is utilized in the design of SNIPERs[1].
T17899	cIAP1 Ligand-Linker Conjugates 9 E3 ligase Ligand-Linker Conjugates 45	Others	Others
	cIAP1 Ligand-Linker Conjugates 9 feature an IAP ligand specifically targeting the E3 ubiquitin ligase, along with a PROTAC linker. It is valuable tools for developing SNIPERs[1].
T30929	Cianopramine hydrochloride Cianopramine HCl,Ro 112465 hydrochloride,Ro-11-2465 hydrochloride
	Cianopramine hydrochloride is a bio-active chemical.
T39103	Pafolacianine OTL 38
	Pafolacianine (OTL 38) is a near-infrared dye-based fluorescent marker utilized for identifying ovarian cancer lesions during surgeries.
T76324	GnRH Associated Peptide (1-24), human
	GnRH Associated Peptide (GAP) (1-24), human 是人类的一个化合物，具体为促性腺激素释放激素相关肽(GAP)的第1至24个氨基酸片段(hGAP-1-24)。该化合物通过3个氨基酸加工位点与黄体生成素释放激素(LH-RH)序列连接。
T82346	Galanin message associated peptide (1-41) amide
	Galanin message-associated peptide (1-41) amide 是肽类激素，结构由41个氨基酸残基组成，并以酰胺形式存在。
T126403	Kaempferol 3-O-vicianoside
	Kaempferol 3-O-vicianoside 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126403，CAS号为 110352-79-9。
T33889	Passitrifasciatin
	Passitrifasciatin is a cyclopentanoid cyanohydrin glycoside isolated from Passiflora trifasciata.
T17885	cIAP1 Ligand-Linker Conjugates 11 E3 ligase Ligand-Linker Conjugates 33	Others	Others
	cIAP1 Ligand-Linker Conjugates 11 is a chemical compound that combines an IAP ligand specifically designed for the E3 ubiquitin ligase with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 11, is useful in the development of SNIPERs[1], allowing for the targeted degradation of proteins.
T17889	cIAP1 Ligand-Linker Conjugates 14 E3 ligase Ligand-Linker Conjugates 36	Others	Others
	cIAP1 Ligand-Linker Conjugates 14 consist of an IAP ligand that targets the E3 ubiquitin ligase and a PROTAC linker. These conjugates, known as cIAP1 Ligand-Linker Conjugates 14, are used in the development of SNIPERs[1].
T79637	CIAC001
	CIAC001是一种丙酮酸激酶PKM2的抑制剂，它展现出了抗神经炎症活性。这种化合物能够抑制LPS诱导的一氧化氮(NO)产生(IC50=2.5 μM)，并保护BV-2免疫活性细胞。在小鼠模型中，CIAC001减轻了慢性吗啡引起的成瘾和神经炎症症状。
TP1420	Microtubule-associated protein tau (26-44)
	Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.
T17896	cIAP1 Ligand-Linker Conjugates 4 E3 ligase Ligand-Linker Conjugates 42	Others	Others
	cIAP1 Ligand-Linker Conjugates 4 is a chemical compound that comprises an IAP ligand specifically designed for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 4, has the potential to be utilized in the development of SNIPERs[1].
T17891	cIAP1 Ligand-Linker Conjugates 2 E3 ligase Ligand-Linker Conjugates 37	Others	Others
	cIAP1 Ligand-Linker Conjugates 2 is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a PROTAC linker. This compound is particularly useful in the design of SNIPERs [1].
T17888	cIAP1 Ligand-Linker Conjugates 6 hydrochloride E3 ligase Ligand-Linker Conjugates 35 hydrochloride	Others	Others
	cIAP1 Ligand-Linker Conjugates 6 hydrochloride is a compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. It is utilized for the purpose of designing SNIPERs[1].
T29840	Alcian blue
	Alcian blue is a copper-containing dye used as a gelling agent for lubricants, for staining of bacteria and for the dyeing of histiocytes and fibroblasts in vivo.
T76323	GnRH Associated Peptide (25-53), human
	GnRH Associated Peptide (GAP) (25-53), human 是来源于人的促性腺激素释放激素相关肽（GAP）的一个特定片段，具体为第25至第53位氨基酸（hGAP-25-53）。本片段可用作免疫原，用以产生含有MC-1、MC-2和MC-3等抗体的抗血清。GAP通过其内含的三个氨基酸加工位点，能与黄体生成素释放激素（LH-RH）序列进行有效连接。
T40861	Nerindocianine
	Nerindocianine is a hydrophilic, fluorescent diagnostic contrast agent that is predominantly metabolized by the kidneys, enabling non-invasive, intraoperative ureteral imaging.
T17897	cIAP1 Ligand-Linker Conjugates 13 E3 ligase Ligand-Linker Conjugates 43	Others	Others
	cIAP1 Ligand-Linker Conjugates 13, containing an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker, are utilized in the development of SNIPERs[1].
T17890	cIAP1 Ligand-Linker Conjugates 2 Hydrochloride E3 ligase Ligand-Linker Conjugates 37 Hydrochloride,cIAP1 Ligand-Linker Conjugates 2 Hydrochloride (1312302-14-9 free base)	Others	Others
	cIAP1 Ligand-Linker Conjugates 2 Hydrochloride is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. It is utilized in the creation of SNIPERs[1].
T124331	4'-Deoxyprovincialin
	4'-Deoxyprovincialin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124331，CAS号为 72057-04-6。
T17900	cIAP1 Ligand-Linker Conjugates 8 E3 ligase Ligand-Linker Conjugates 46	Others	Others
	cIAP1 Ligand-Linker Conjugates 8 comprises an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is specifically utilized for the purpose of SNIPER design[1].
T17892	cIAP1 Ligand-Linker Conjugates 12 E3 ligase Ligand-Linker Conjugates 38	Others	Others
	cIAP1 Ligand-Linker Conjugates 12 is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 12, is valuable for creating SNIPERs[1].
T17901	cIAP1 Ligand-Linker Conjugates 10 E3 ligase Ligand-Linker Conjugates 47	Others	Others
	cIAP1 Ligand-Linker Conjugates 10 comprise of an IAP ligand and a PROTAC linker, which facilitates the design of SNIPERs. These conjugates incorporate an IAP ligand that interacts with the E3 ubiquitin ligase, and a PROTAC linker. SNIPERs can be developed using cIAP1 Ligand-Linker Conjugates 10.
T69322	cIAP1-IN-D19
	cIAP1-IN-D19 is an inhibitor of E3 ligase activity of cIAP1.
T17887	cIAP1 Ligand-Linker Conjugates 15 E3 ligase Ligand-Linker Conjugates 34	Others	Others
	cIAP1 Ligand-Linker Conjugates 15 consists of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 15, is suitable for the development of SNIPERs[1].
T29841	Alcian yellow C.I. Ingrain Yellow 1
	Alcian yellow is a biomarker.
T17893	cIAP1 Ligand-Linker Conjugates 5 E3 ligase Ligand-Linker Conjugates 39	Others	Others
	cIAP1 Ligand-Linker Conjugates 5 is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 5, is specifically designed for the development of SNIPERs[1].
T10496	Bencianol ZY15051,苯西阿诺	Others	Others
	Bencianol is a semisynthetic flavonoid with anti-spasmogenic activities.
T124855	Lucialdehyde A
	Lucialdehyde A 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124855。

化合物

CIA-1 (Free base)

Cat.No: T71534L

Synonym: CIA-1(Free base）

Target: Gamma-secretase

CIA-1 hcl(452087-38-6 Free base)

Cat.No: T71534

Target: Gamma-secretase

Cat.No: T2057

Target: Dehydrogenase

Cat.No: T4195

Synonym: PT 9 base,倍他司汀,Vasomotal,Serc base

Target: Histamine Receptor

Betahistine dihydrochloride

Cat.No: T0246

Synonym: PT-9,Betahistine 2HCl,盐酸倍他司汀

Target: Histamine Receptor

Cat.No: T2125

Synonym: GSK1120212,曲美替尼,JTP-74057

Target: Apoptosis, MEK, Autophagy

DCAI Hydrochloride

Cat.No: T72006

Trametinib (DMSO solvate)

Cat.No: T5857

Synonym: Trametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfoxide,JTP-74057 (DMSO solvate)

Target: Apoptosis, MEK

GnRH Associated Peptide (GAP) (1-13), human Acetate

Cat.No: T21649L

Synonym: GnRH Associated Peptide (GAP) (1-13), human Acetate (100111-07-7 Free base)

Target: Others

Cat.No: T68043

Synonym: Ciamexone,BM 41332,BM41332,BM-41332

Target: Others

cIAP1 ligand 1

Cat.No: T17870

Synonym: E3 ligase Ligand 12

Target: Others

cIAP1 Ligand-Linker Conjugates 15 hydrochloride

Cat.No: T17886

Synonym: E3 ligase Ligand-Linker Conjugates 34 hydrochloride

Target: Others

cIAP1 Ligand-Linker Conjugates 3

Cat.No: T17894

Synonym: E3 ligase Ligand-Linker Conjugates 40

Target: Others

XIAP/cIAP1 antagonist-1

Cat.No: T64302

cIAP1 ligand 2

Cat.No: T17869

Synonym: E3 ligase Ligand 11

Target: Others

Cat.No: T25248

Synonym: Ro 112465,Ro-112465,Ro112465

cIAP1 Ligand-Linker Conjugates 1

Cat.No: T17895

Synonym: E3 ligase Ligand-Linker Conjugates 41

Target: Others

cIAP1 Ligand-Linker Conjugates 16

Cat.No: T39609

Synonym: cIAP1 Ligand-Linker Conjugates 16

Cat.No: T29390

Synonym: 3-Carboxyphenyl((N-((4-iodophenyl)acetyl)amino)methyl)phosphonate

cIAP1 Ligand-Linker Conjugates 11 Hydrochloride

Cat.No: T17884

Synonym: E3 ligase Ligand-Linker Conjugates 33 Hydrochloride

Target: Others

cIAP1 Ligand-Linker Conjugates 7

Cat.No: T17898

Synonym: E3 ligase Ligand-Linker Conjugates 44

Target: Others

cIAP1 Ligand-Linker Conjugates 9

Cat.No: T17899

Synonym: E3 ligase Ligand-Linker Conjugates 45

Target: Others

Cianopramine hydrochloride

Cat.No: T30929

Synonym: Cianopramine HCl,Ro 112465 hydrochloride,Ro-11-2465 hydrochloride

Cat.No: T39103

Synonym: OTL 38

GnRH Associated Peptide (1-24), human

Cat.No: T76324

Galanin message associated peptide (1-41) amide

Cat.No: T82346

Kaempferol 3-O-vicianoside

Cat.No: T126403

Passitrifasciatin

Cat.No: T33889

cIAP1 Ligand-Linker Conjugates 11

Cat.No: T17885

Synonym: E3 ligase Ligand-Linker Conjugates 33

Target: Others

cIAP1 Ligand-Linker Conjugates 14

Cat.No: T17889

Synonym: E3 ligase Ligand-Linker Conjugates 36

Target: Others

Cat.No: T79637

Microtubule-associated protein tau (26-44)

Cat.No: TP1420

cIAP1 Ligand-Linker Conjugates 4

Cat.No: T17896

Synonym: E3 ligase Ligand-Linker Conjugates 42

Target: Others

cIAP1 Ligand-Linker Conjugates 2

Cat.No: T17891

Synonym: E3 ligase Ligand-Linker Conjugates 37

Target: Others

cIAP1 Ligand-Linker Conjugates 6 hydrochloride

Cat.No: T17888

Synonym: E3 ligase Ligand-Linker Conjugates 35 hydrochloride

Target: Others

Cat.No: T29840

GnRH Associated Peptide (25-53), human

Cat.No: T76323

Cat.No: T40861

cIAP1 Ligand-Linker Conjugates 13

Cat.No: T17897

Synonym: E3 ligase Ligand-Linker Conjugates 43

Target: Others

cIAP1 Ligand-Linker Conjugates 2 Hydrochloride

Cat.No: T17890

Synonym: E3 ligase Ligand-Linker Conjugates 37 Hydrochloride,cIAP1 Ligand-Linker Conjugates 2 Hydrochloride (1312302-14-9 free base)

Target: Others

4'-Deoxyprovincialin

Cat.No: T124331

cIAP1 Ligand-Linker Conjugates 8

Cat.No: T17900

Synonym: E3 ligase Ligand-Linker Conjugates 46

Target: Others

cIAP1 Ligand-Linker Conjugates 12

Cat.No: T17892

Synonym: E3 ligase Ligand-Linker Conjugates 38

Target: Others

cIAP1 Ligand-Linker Conjugates 10

Cat.No: T17901

Synonym: E3 ligase Ligand-Linker Conjugates 47

Target: Others

Cat.No: T69322

cIAP1 Ligand-Linker Conjugates 15

Cat.No: T17887

Synonym: E3 ligase Ligand-Linker Conjugates 34

Target: Others

Cat.No: T29841

Synonym: C.I. Ingrain Yellow 1

cIAP1 Ligand-Linker Conjugates 5

Cat.No: T17893

Synonym: E3 ligase Ligand-Linker Conjugates 39

Target: Others

Cat.No: T10496

Synonym: ZY15051,苯西阿诺

Target: Others

Cat.No: T124855

Cat. No.	Product Name	Target	Signaling Pathways
T5S2129	Sciadopitysin	TNF; NF-κB	Apoptosis; NF-κB
	Sciadopitysin 是一种双黄酮类化合物，来自银杏叶片中。它通过抑制NF-κB 活化并降低c-Fos 和NFATc1的表达来抑制 RANKL 诱导的破骨细胞生成和骨丢失。
TN4455	Lucialdehyde B	Integrase; HSV	Microbiology/Virology
	Lucialdehyde B exhibits potent inhibitory activity against herpes simplex virus. It shows cytotoxic effects on Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines.
TN6102	Pistaciamide
	Pistaciamide 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6102，CAS号为 1029004-83-8。
TN5364	Boscialin
	Boscialin can inhibit signal transducer and activator of transcription 1 translocation at a concentration of 10 uM.
TN4195	Helicianeoide A	Others	Others
	Helicianeoide A 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4195，CAS号为 496066-82-1。
TN2700	2,3-dihydrosciadopitysin	Others	Others
	2,3-dihydrosciadopitysin是一种天然产物，属于罗汉松科罗汉松属，其产品编号为 TN2700，CAS号为 34421-19-7。2,3-dihydrosciadopitysin可用作对照参考。
T39435	Myrciacetin
	Myrciacetin, a flavonoid derived from Rhododendron dauricum, exhibits inhibitory activity against rat lens aldose reductase, as demonstrated by an IC50 value of 13 μM.
TN4196	Helicianeoide B	Others	Others
	Helicianeoide B 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4196，CAS号为 496066-89-8。
TN4598	Myrciaphenone A	Others	Others
	Myrciaphenone A is a natural product from Limoniastrum feei (Girard) Batt.
T3662	Eleutheroside E	NF-κB	NF-κB
	Eleutheroside E 是刺五加的重要成分，具有抗炎，保护缺血心脏的功能。

天然产物

Cat.No: T5S2129

Target: TNF, NF-κB

Cat.No: TN4455

Target: Integrase, HSV

Cat.No: TN6102

Cat.No: TN5364

Helicianeoide A

Cat.No: TN4195

Target: Others

2,3-dihydrosciadopitysin

Cat.No: TN2700

Target: Others

Cat.No: T39435

Helicianeoide B

Cat.No: TN4196

Target: Others

Myrciaphenone A

Cat.No: TN4598

Target: Others

Eleutheroside E

Cat.No: T3662

Target: NF-κB

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03341	ASF1B Protein, Human, Recombinant (His) anti-silencing function 1B histone chaperone,CIA-II	Human	Baculovirus Insect Cells
	The histone chaperone anti-silencing factor 1a (ASF1a) interacts with MDC1 and is recruited to sites of DSBs to facilitate the interaction of phospho-ATM with MDC1 and phosphorylation of MDC1, which are required for the recruitment of RNF8/RNF168 histone ubiquitin ligases. Thus, ASF1a deficiency reduces histone ubiquitination at DSBs, decreasing the recruitment of 53BP1, and decreases NHEJ, rendering cells more sensitive to DSBs. This role of ASF1a in DSB repair cannot be provided by the closely...
TMPJ-01399	ASF1A Protein, Human, Recombinant (His, T7) CIA,Anti-Silencing Function Protein 1 Homolog A,ASF...	Human	E. coli
	Human Histone Chaperone ASF1A (ASF1A) belongs to the H3/H4 family of histone chaperone proteins. ASF1A is ubiquitously expressed in many cells and tissues, interacting with histones H3 and H4. ASF1A cooperates with Chromatin Assembly Factor 1 to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. In addition, ASF1A is necessary for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associat...
TMPH-00296	Pregnancy-associated protein bPAP Protein, Bovine, Recombinant (His & Myc)	Bovine	E. coli
	Pregnancy-associated protein bPAP Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.3 kDa and the accession number is P84291.
TMPH-00043	Fanconi-associated nuclease 1 Protein, Ailuropoda melanoleuca, Recombinant (His & Myc)	Ailuropoda melanoleuca	E. coli
	Fanconi-associated nuclease 1 Protein, Ailuropoda melanoleuca, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.5 kDa and the accession number is D2HNY3.
TMPH-00454	OBP28 Protein, Culex quinquefasciatus, Recombinant (His & Myc)	Culex quinquefasciatus	E. coli
	N/A. OBP28 Protein, Culex quinquefasciatus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 22 kDa and the accession number is B0XC79.
TMPH-03035	M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His)	Myrmecia pilosula	Baculovirus Insect Cells
	Heterodimer protein that may serve both defensive (pain-inducing) and predatory (insecticidal) roles. Has membrane-disrupting activity and shows induction of non-specific calcium influx into cells,. Shows broad-spectrum activity against a diverse range of bacteria, and cell lines, as well as hemolytic activity (EC(50)=2.18 uM). In vivo, shows moderate insecticidal activity against D.melanogaster and potent anthelmintic activity against the veterinary nematode H.contortus. In addition, intraplant...
TMPH-03513	Plastocyanin Protein, Spinacia oleracea, Recombinant (His & SUMO)	Spinacia oleracea	E. coli
	Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I. Plastocyanin Protein, Spinacia oleracea, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 26.4 kDa and the accession number is P00289.
TMPH-00455	OBP28 Protein, Culex quinquefasciatus, Recombinant (His)	Culex quinquefasciatus	P. pastoris (Yeast)
	N/A. OBP28 Protein, Culex quinquefasciatus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 16.1 kDa and the accession number is B0XC79.
TMPH-03706	LEB6 Protein, Vicia faba, Recombinant (His)	Vicia faba	P. pastoris (Yeast)
	This protein found in the seeds of many leguminous and non-leguminous plants is the source of sulfur-containing amino acids in seed meals. LEB6 Protein, Vicia faba, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 19.0 kDa and the accession number is P16079.
TMPY-01176	cIAP1 Protein, Human, Recombinant (Avi) Hiap-2,API1,HIAP2,RNF48,baculoviral IAP repeat containing 2,...	Human	E. coli
	The cellular inhibitor of apoptosis protein-1 (cIAP1) is a member of the Inhibitor of Apoptosis family proteins are (IAP) whose members are characterized by a novel domain of about 70 amino acids termed baculoviral IAP repeats (BIRs). The BIR domains of cIAP1 and cIAP2 bind to caspases, the key effector proteases of apoptosis. The IAP protein family which can enhance cell survival are crucial regulators of programmed cell death. Both cIAP1 and cIAP2 are the E3 ubiquitin protein isopeptide ligase...
TMPH-00028	Adeno-associated virus 2 (isolate Srivastava/1982) Rep78 Protein (His & MBP) Protein Rep78	AAV-2	E. coli
	Plays an essential role in the initiation of viral DNA synthesis. Binds specifically to an inverted terminal repeat element (ITR) on the 3' and 5' ends of the viral DNA, where it cleaves a site specifically to generate a priming site for initiation of the synthesis of a complementary strand. Plays also a role as transcriptional regulator, DNA helicase and as key factors in site-specific integration of the viral genome. Regulates host PKA activity by interacting with host PRKX as a mechanism of i...
TMPJ-00353	ILDR2 Protein, Human, Recombinant (His) Angulin-3,immunoglobulin-like domain containing receptor 2,D...	Human	HEK293 Cells
	ILDR2 is a member of the B7-like family of proteins that regulate T cell activity, is also a known endoplasmic reticulum molecule that regulates lipid homeostasis. The human ILDR2 lumenal domain shares a 99% and 98% homology with the mouse and rat respectively. The human gene encoding ILDR2 is located in a region on Chr1q23–25 that has been associated with type 2 diabetes. ILDR2 plays critical roles in hepatic clearance of lipoproteins and in lipid homeostasis. ILDR2 regulates human dendritic ce...

重组蛋白

ASF1B Protein, Human, Recombinant (His)

Cat.No: TMPY-03341

Species: Human

Expression System: Baculovirus Insect Cells

ASF1A Protein, Human, Recombinant (His, T7)

Cat.No: TMPJ-01399

Species: Human

Expression System: E. coli

Pregnancy-associated protein bPAP Protein, Bovine, Recombinant (His & Myc)

Cat.No: TMPH-00296

Species: Bovine

Expression System: E. coli

Fanconi-associated nuclease 1 Protein, Ailuropoda melanoleuca, Recombinant (His & Myc)

Cat.No: TMPH-00043

Species: Ailuropoda melanoleuca

Expression System: E. coli

OBP28 Protein, Culex quinquefasciatus, Recombinant (His & Myc)

Cat.No: TMPH-00454

Species: Culex quinquefasciatus

Expression System: E. coli

M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His)

Cat.No: TMPH-03035

Species: Myrmecia pilosula

Expression System: Baculovirus Insect Cells

Plastocyanin Protein, Spinacia oleracea, Recombinant (His & SUMO)

Cat.No: TMPH-03513

Species: Spinacia oleracea

Expression System: E. coli

OBP28 Protein, Culex quinquefasciatus, Recombinant (His)

Cat.No: TMPH-00455

Species: Culex quinquefasciatus

Expression System: P. pastoris (Yeast)

LEB6 Protein, Vicia faba, Recombinant (His)

Cat.No: TMPH-03706

Species: Vicia faba

Expression System: P. pastoris (Yeast)

cIAP1 Protein, Human, Recombinant (Avi)

Cat.No: TMPY-01176

Species: Human

Expression System: E. coli

Adeno-associated virus 2 (isolate Srivastava/1982) Rep78 Protein (His & MBP)

Cat.No: TMPH-00028

Species: AAV-2

Expression System: E. coli

ILDR2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00353

Species: Human

Expression System: HEK293 Cells

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