101
2
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T26629 |
Angstrom6
A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide |
PAI-1 | Metabolism |
Angstrom6 (A-6 peptide) 是一种从单链尿激酶纤溶酶原激活剂(scuPA)中提取的 8 肽,它能干扰 uPA/uPAR 级联反应并抑制下游效应。Angstrom6 具有抗肿瘤活性,能通过与 CD44 结合并调节 CD44 介导的细胞信号传导,抑制肿瘤细胞的迁移、侵袭和转移。 | |||
T35867 |
TRAP-6 Peptide (trifluoroacetate salt)
|
||
TRAP-6 peptide is a hexapeptide corresponding to residues 42-47 of protease-activated receptor 1 (PAR1). It acts as an agonist of PAR1, inducing platelet aggregation in human platelet-rich plasma ex vivo (EC50 = 0.8 μM). TRAP-6 (0.3 and 0.6 mg/kg) has a triphasic effect on mean arterial blood pressure (MAP) in anesthetized rats with a short decrease, an increase, and then a longer decrease in MAP following intravenous administration. | |||
T81231 |
S6 peptide
|
||
S6 peptide, 作为一种潜在重要的核纤维层蛋白激酶,参与了机械负荷诱发的心肌肥厚过程并可被多种生长因子所激活。 | |||
T76372 |
TRAF6 peptide
|
||
TRAF6 peptide 是一种特异性的TRAF6-p62相互作用抑制剂。TRAF6 peptide 能消除 NGF 依赖性TrkA 泛素化。TRAF6 peptide 在诸如阿尔茨海默症 (AD)、帕金森、ALS、头部外伤、癫痫和中风等神经系统性疾病中具有较好的研究潜力。 | |||
T80686 | γ-AA peptide P6 | ||
γ-AA peptide P6 作为E6相关蛋白(E6AP)的有效激活剂, 在体外重组反应中能够促进E6AP的自我泛素化以及催化底物的泛素化作用。此外,γ-AA peptide P6 在细胞内部能够增强E6AP底物的泛素化,并加速其通过蛋白酶体的降解过程。 | |||
T78221 |
TRAF6 peptide TFA
|
E1/E2/E3 Enzyme | Ubiquitination |
TRAF6 peptide TFA是一种抑制TRAF6-p62相互作用的特异性分子,可抑制NGF依赖的TrkA泛素化,展现在阿尔茨海默症(AD)、帕金森病、ALS、创伤性脑损伤、癫痫和中风等神经系统疾病研究中的应用潜力。 | |||
TP1422 |
Interleukin (IL)-6 Receptor
|
Others | Others |
Interleukin (IL)-6 Receptor 是一种肽,来源于白细胞介素6受体。 | |||
T38852L |
TRAP-6 amide acetate
|
Protease-activated Receptor | GPCR/G Protein |
TRAP-6 amide acetate 是一种 PAR-1 凝血酶受体激动剂肽。 | |||
TP1579 |
Angiotensin I/II (1-6)
Angiotensin I/II 1-6 |
RAAS; Others | Endocrinology/Hormones; Others |
Angiotensin I/II (1-6) 是由血管紧张素 I/II 肽转化而来,含有 1-6 个氨基酸的多肽。血管紧张素 I 被血管紧张素转换酶水解,形成具有生物活性的血管紧张素 II。血管紧张素 II 用于高血压、特发性膜性肾病和肾素-血管紧张素系统的研究。 | |||
TP1484L |
α2β1 Integrin Ligand Peptide acetate
α2β1 Integrin Ligand Peptide acetate (134580-64-6) |
Integrin | Cytoskeletal Signaling |
α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) 是 α2β1 整合素受体的潜在拮抗剂。它与细胞膜上的 α2β1 整合素受体相互作用,介导细胞外信号进入细胞。 | |||
T21674L |
PKA inhibitor fragment (6-22) amide Acetate
PKA inhibitor fragment (6-22) amide Acetate(121932-06-7 Free base) |
PKA | Tyrosine Kinase/Adaptors |
PKA inhibitor fragment (6-22) amide Acetate 是一种通过结合底物位点选择性抑制PKA 活性的合成肽(IC50 < 2 nM)。 | |||
T9280 |
CS-0047390
(S)-Di-tert-butyl 2-(3-((S)-6-amino-1-(tert-butoxy)-1-oxohexan-2-yl)ureido)pentanedioate |
Others | Others |
CS-0047390 ((S)-Di-tert-butyl 2-(3-((S)-6-amino-1-(tert-butoxy)-1-oxohexan-2-yl)ureido)pentanedioate)又称 tert-Butyl-DCL,PSMA 抑制剂,是一种放射显影多肽试剂。 | |||
TP2047L |
CRF (6-33) acetate(120066-38-8 free base)
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CRFR | GPCR/G Protein |
CRF (6-33) acetate(120066-38-8 free base) 是促肾上腺皮质激素释放因子结合蛋白 (CRFBP) 抑制肽;从 CRFBP 中替换 CRF。在体内抑制肥胖大鼠的体重增加并增加运动活动。 | |||
TP1289 |
Cardiotoxin Analog (CTX) IV (6-12) TFA
Cardiotoxin Analog (CTX) IV (6-12) (TFA)(115722-23-1,FREE) |
Others | Others |
Cardiotoxin Analog (CTX) IV (6-12) TFA(115722-23-1 free base) 是 Cardiotoxin Analog (CTX) IV 的部分肽。从台湾眼镜蛇毒液中分离出的心脏毒素类似物 IV。 CTX IV 是一种独特的蛇毒心脏毒素。 | |||
TP1315 |
c-Myc Peptide Trifluoroacetate
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Others | Others |
c-Myc Peptide Trifluoroacetate (145646-22-6 free base) 是一种合成肽,对应于人类 c-myc 蛋白的 C 末端氨基酸 (410-419),参与调控生长相关基因的转录。 | |||
TP1866L |
β-amyloid 1-11 acetate(190436-05-6 free base)
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Beta Amyloid | Neuroscience |
β-amyloid 1-11 acetate(190436-05-6 free base) 是 Amyloid-β 肽的片段,可用于神经系统疾病的研究。 | |||
T8559 |
Galnon TFA(475115-35-6(free base))
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
GALNON TFA(475115-35-6(free base)) 是一种新型非肽甘丙肽受体激动剂(GAL1 和 GAL2,Ki 分别为 11.7 和 34.1 μM)。 | |||
T21618L |
Myelin Basic Protein (87-99) Acetate
Myelin Basic Protein (87-99) Acetate (118506-26-6 Free base) |
Others | Others |
Myelin Basic Protein (87-99) Acetate (Myelin Basic Protein (87-99) Acetate (118506-26-6 Free base)) 是一种致脑炎肽,可诱导碱性蛋白特异性 T 细胞增殖。 它导致外周血单核细胞中的 Th1 极化,这与多发性硬化症 (MS) 有牵连。 | |||
TP1104L |
Melanin Concentrating Hormone, salmon acetate
MCH (salmon),Melanin Concentrating Hormone, salmon acetate(87218-84-6 free base) |
Others; Melanin-concentrating Hormone Receptor (MCHR) | GPCR/G Protein; Others |
Melanin Concentrating Hormone, salmon acetate (MCH (salmon))(87218-84-6 free base) 是一种 19 个氨基酸的环状肽,主要在下丘脑中表达。 | |||
TP1458L |
Arg-Gly-Glu-Ser acetate(93674-97-6 free base)
|
Others | Others |
Arg-Gly-Glu-Ser acetate(93674-97-6 free base) 是一种 RGD 相关肽,可控制纤维蛋白原与活化血小板结合的 RGDS 活性。 | |||
TP1943L1 |
pep2-EVKI acetate(1315378-67-6 free base)
|
GluR | Neuroscience |
pep2-EVKI acetate(1315378-67-6 free base) 是一种细胞渗透性肽。 它干扰与 C 激酶 (PICK1) 相互作用的蛋白质和 GluR2 AMPA 受体亚基之间的相互作用。 | |||
TP1605L1 |
Allatostatin IV TFA(123338-13-6 free base)
|
Others | Others |
Allatostatin IV TFA(123338-13-6 free base) 是一种八肽胺,是在昆虫中发现的抑制(allatostatins)或刺激(allatotropins)保幼激素(JH)合成的调节肽家族的成员。 | |||
TP1293 |
Jagged-1 (188-204) TFA(219127-21-6 free base)
Jagged-1 (188-204) TFA |
Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
Jagged-1 (188-204) TFA(219127-21-6 free base) 是 JAG-1 蛋白的一个片段。 JAG-1 是 Notch 配体,是一种在皮肤中表达最明显的肽。 JAG-1 诱导表皮成熟。将淹没的角质形成细胞单层暴露于钙浓度升高的 JAG-1 会产生具有 loricrin 表达和 NF-alphaB 激活的分层。 | |||
TP1606L |
NLS PKKKRKV acetate(95088-49-6 free base)
|
Others | Others |
NLS PKKKRKV acetate(95088-49-6 free base) 是从大猿病毒40肿瘤抗原(SV40大T 抗原)衍生的肽,是基因转移研究领域中增强核入口的一种方法。 | |||
T15368L |
Galantide acetate
Galantide acetate(138579-66-5 Free base) |
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Galantide acetate 是一种特殊的甘丙肽受体 (galanin receptor) 拮抗剂,是一种由甘丙肽和 P 物质片段组成的肽段,在大鼠下丘脑可识别两类甘丙肽结合位点 (KD 分别小于 0.1 nM 和 ~6 nM)。Galantide 剂量依赖性 (IC50=1.0 nM) 拮抗甘丙肽介导的葡萄糖诱导的小鼠胰岛胰岛素分泌抑制。Galantide acetate 似乎与单一的 SP 受体群结合 (KD~40 nM)。 | |||
TP1696L |
CGGRGD acetate(1260223-44-6 free base)
|
Others | Others |
CGGRGD acetate(1260223-44-6 free base) 是一种以半胱氨酸为 n 端的 RGD 衍生物。 CGGRGD 采用固相多肽合成技术合成,在PCL 纤维表面添加氨基2-氰基苯并噻唑(2-cyanobenzothiazole)(2-cyanobenzothiazole (CBT))进行氨化。 | |||
TP2312 |
MOTS-c(Human) Acetate(1627580-64-6 free)
|
Others; AMPK | Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling |
MOTS-c(Human) Acetate(1627580-64-6 free)是一种线粒体衍生肽。 它诱导 AMP 类似物 AICAR 的积累,增加 AMPK 的激活和其下游 GLUT4 的表达。它可诱导葡萄糖摄取并提高胰岛素敏感性。 它对调节肥胖、糖尿病、运动和长寿有重要意义。 | |||
TP1930L1 |
Spexin acetate(1370290-58-6 free base)
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Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Spexin acetate(1370290-58-6 free base) 是一种有效的甘丙肽受体 2/3 (GAL2/GAL3) 激动剂(EC50 值分别为 45.7 和 112.2 nM)。对甘丙肽受体 1 没有显着的活性。抑制脂肪细胞对长链脂肪酸的摄取并减少饮食诱导的肥胖小鼠和大鼠的食物消耗。减少金鱼的 LH 分泌。在体内表现出抗焦虑作用。 | |||
T38852 |
TRAP-6 amide
|
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TRAP-6 amide is a PAR-1 thrombin receptor agonist peptide. | |||
T38887 |
TRAP-6 amide TFA
|
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TRAP-6 amide TFA is a PAR-1 thrombin receptor agonist peptide. | |||
T76650 |
PAR-2 (1-6) (human)
|
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PAR-2 (1-6) (human) (SLIGKV) 是 PAR-2的多肽激动剂。 | |||
T41012 |
Mad1 (6-21)
Mad1 (6-21) |
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Mad1 (6-21) is a peptide fragment derived from the Mad1 protein, specifically encompassing residues 6 to 21. This fragment exhibits binding affinity towards the mammalian Sin3A PAH2 domain, with a Kd value of approximately 29 nM. | |||
T36289 |
Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA
|
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Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a peptide that acts as an agonist for the proteinase-activated receptor (PAR-3)[1]. | |||
T13560 | AT-1002 | Others | Others |
AT-1002 is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide. | |||
TP1283 |
VIP(6-28)(human, rat, porcine, bovine)
|
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VIP(6-28)(human, rat, porcine, bovine) is a potent antagonist that effectively counteracts the effects of exogenous vasoactive intestinal peptide (VIP) on cyclic adenosine monophosphate (cAMP) signaling. | |||
TP1603 |
β-Casomorphin (1-6), bovine
|
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β-Casomorphin (1-6), bovine is a opioid-like bioactive peptide of β-Casomorphin. | |||
T13560L |
AT-1002 TFA (835872-35-0 free base)
AT-1002 TFA |
Others | Others |
AT-1002 TFA is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide. | |||
T73811 | AT-1002 TFA | ||
AT-1002 TFA 是一种 6 聚体合成肽,是一种紧密连接 (junction) 的调节剂和吸收增强剂。 | |||
T81613 |
Oligopeptide-6
|
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Oligopeptide-6作为一种生物活性肽,具备显著的保湿功能,并广泛作为化妆品配料使用。 | |||
TP2047 |
CRF(6-33)(human)
CRF (6-33) |
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CRF(6-33)(human) is a Corticotropin-releasing factor binding protein (CRFBP) inhibitor peptide; displaces CRF from CRFBP. Suppresses body weight gain and increases motor activity in obese rats in vivo. | |||
TP1747 |
Bradykinin (1-6)
|
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Bradykinin (1-6) is an amino-truncated Bradykinin peptide. Bradykinin (1-6) is a stable metabolite of Bradykinin, cleaved by carboxypeptidase Y (CPY).Bradykinin (1-6) is a fragment of bradykinin. Bradykinin activates pain receptors. It induces smooth musc | |||
T25481 |
H 77
H77,H-77 |
||
H 77 is a new effective renin inhibitor. H 77 is angiotensinogen (6-13)-octapeptide in which the peptide bond -CO-NH- at the Leu(9)-Leu(11) linkage is replaced by a -CH2-NH- bond. | |||
T81565 |
Palmitoyl hexapeptide-14
Palmitoyl hexapeptide-6 |
||
Palmitoyl hexapeptide-14(亦称为Palmitoyl hexapeptide-6)是一种生物活性肽,因其抗皱功能而常作为化妆品成分。 | |||
TD0062 |
6-CR110 [6-Carboxyrhodamine 110] *Single isomer*
6-羧基罗丹明110(单一化合物) |
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6-CR110 [6-Carboxyrhodamine 110] *Single isomer* is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM. | |||
TP1455 |
Cardiotoxin Analog (CTX) IV (6-12)
Cardiotoxin Analog (CTX) IV 6-12 |
||
Cardiotoxin Analog (CTX) IV (6-12) is a part peptide of Cardiotoxin Analog (CTX) IV. Cardiotoxin analogues IV isolated from the venom of Taiwan Cobra. | |||
TP1284 |
LL-37, Human TFA (154947-66-7 free base)
LL-37, Human TFA |
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Human LL-37 is a 37 amino acid cationic (6+) peptide and has been widely studied. LL-37 penetrates the bacterial membrane and forms pores in the membrane. | |||
TP2291 |
signal transducer and activator of transcription 6 fragment
|
Others | Others |
The signal transducer and activator of transcription 6 fragments is a peptide with the sequence H2N-Ser-Tyr-Trp-Ser-Asp-Arg-Leu-Ile-Ile-OH, MW= 1152.3. | |||
TD0063 |
5(6)-CR110, SE [5-(and 6)-Carboxyrhodamine 110, succinimidyl ester] *Mixed isomers*
5(6)-羧基罗丹明110琥珀酰亚胺酯(混合物) |
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5(6)-CR110, SE [5-(and 6)-Carboxyrhodamine 110, succinimidyl ester] *Mixed isomers* is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM. | |||
T26936 |
C188
Cpd188,STAT3-IN-C188,Cpd-188,C 188,C-188 |
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C188 is a cell-permeable naphthol compound and a STAT3 inhibitor. C188 inhibits IL-6-stimulated STAT3 Tyr705 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket, while exhibiting little effect agai | |||
TD0065 |
6-CR110, SE [6-Carboxyrhodamine 110, succinimidyl ester]*Single isomer*
6-羧基罗丹明110琥珀酰亚胺酯(单一化合物) |
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6-CR110, SE [6-Carboxyrhodamine 110, succinimidyl ester]*Single isomer* is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5145 |
Oxytocin acetate
Oxytocic hormone acetate,α-Hypophamine acetate,Oxytocin acetate (50-56-6 free base),醋酸催产素 |
Oxytocin Receptor | Endocrinology/Hormones; GPCR/G Protein |
Oxytocin acetate (α-Hypophamine acetate) 是哺乳动物的神经垂体激素,是多效的下丘脑肽,是催产素受体的配体,有助于分娩、哺乳和亲社会行为。它可作为一种压力应对分子,具有抗炎、抗氧化剂和保护作用。 | |||
T80349 |
Maximin H4
|
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Maximin H4是一种来自中华红腹蟾蜍(Bombina maxima)皮肤分泌物的抗菌肽,具有针对Escherichia coli ATCC25922、Staphylococcus aureus ATCC2592、Bacillus pyocyaneus CMCCB1010和Candida albicans ATCC2002的抗菌活性。其最小抑菌浓度(MIC)值依次为12、6、12、6 μg/ml。 |