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Search Results for " 安脉生 "

1

抑制剂 & 化合物

19

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T0504	Cyclandelate 安脉生,BS 572,环扁桃酯,3,5,5-Trimethylcyclohexyl mandelate	Acyltransferase	Metabolism
	Cyclandelate (BS 572) 是直接作用的平滑肌松弛剂，用于扩张血管。

化合物

Cat.No: T0504

Synonym: 安脉生,BS 572,环扁桃酯,3,5,5-Trimethylcyclohexyl mandelate

Target: Acyltransferase

Cat. No.	Product Name	Target	Signaling Pathways
T3793	(20R)-Ginsenoside Rh1 20(R)-Ginsenoside Rh1,人参皂苷 R-RH1,人参皂苷R-RH1	Others	Others
	(20R)-Ginsenoside Rh1 (20(R)-Ginsenoside Rh1) 是 Ginsenoside Rh1 的 R 型异构体，分离自 Panax Ginseng 中，能够阻碍凝血酶诱导的纤维蛋白原向纤维蛋白的转化。
T3392	Sinapine thiocyanate	P-gp; AChE	Membrane transporter/Ion channel; Neuroscience
	Sinapine thiocyanate 是萝卜中分离出来的一种生物碱，具有抗炎、抗氧化、抗肿瘤、抗血管生成和放射防护作用。它还是乙酰胆碱酯酶抑制剂，可用于研究阿尔茨海默症，共济失调，重症肌无力和帕金森氏病。
T5251	Phenylpyruvic acid 2-Oxo-3-phenylpropanoic acid,3-Phenylpyruvic acid,苯丙酮酸	Others; Endogenous Metabolite	Metabolism; Others
	Phenylpyruvic acid (3-Phenylpyruvic acid) 可以通过乳酸脱氢酶合成3-苯基乳酸 (PLA)。
TQ0176	(-)-Isocorypalmine Tetrahydrocolumbamine,(-)-异延胡索单酚碱,(S)-Tetrahydrocolumbamine	Dopamine Receptor; Antifungal	GPCR/G Protein; Microbiology/Virology; Neuroscience
	(-)-Isocorypalmine ((S)-Tetrahydrocolumbamine) 是一种多巴胺受体配体，从延胡索粗碱中分离得到。重组CYP719A21 对 (-)-Isocorypalmine 具有严格的底物特异性和高亲和力 (Km=4.63 μM)。
T2771	Orcinol glucoside Sakakin,苔黑酚葡萄糖苷	Antioxidant	oxidation-reduction
	Orcinol glucoside (Sakakin) 是一种提取自莪术中的活性成分，具有抗抑郁活性。它能诱导 MSC 转化为成骨细胞，并通过 Wnt/β-catenin 信号通路阻断脂肪形成。
T2S2109	Skimmianine beta-Fagarine,Skimmianin,茵芋碱,Chloroxylonine,Skimmiamine	Others	Others
	Skimmianine (Chloroxylonine) 是一种呋喹啉类生物碱，主要存在于芸香科，具有抗炎、抗痉挛和抗血小板聚集活性。它对多种癌细胞系具有细胞毒性和基因毒性。
T4813	L-Citrulline	Endogenous Metabolite	Metabolism
	L-Citrulline 是一种氨基酸，源自于精氨酸-瓜氨酸途径获得的 l-精氨酸，或脯氨酸、谷氨酰胺和谷氨酸盐的分解代谢过程中产生的鸟氨酸。
T3758	2,6-Dimethoxybenzoic acid	Others; Endogenous Metabolite	Metabolism; Others
	2,6-Dimethoxybenzoic acid 是一种邻甲氧苯甲酸及其衍生物。
TJO2758	D-Glucuronic acid D-葡萄糖醛酸,Aldehydo-D-Glucuronic Acid	Others; Endogenous Metabolite	Metabolism; Others
	D-Glucuronic acid (Aldehydo-D-Glucuronic Acid) 是一种从许多树胶中分离出的重要中间体。它对皮肤具有抗炎作用。它及其衍生物葡萄糖醛酸内酯作为预防人类健康的肝脏解毒剂。
T2789	Scutellarin 黄岑素,野黄芩苷,Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide	Akt; HIV Protease; STAT	Cytoskeletal Signaling; JAK/STAT signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Scutellarin (Scutellarein-7-glucuronide) 是从黄芩中分离的黄酮，可抑制破骨细胞中 RANKL 介导的 MAPK 和 NF-κB 信号通路，并下调 HCC 细胞中的 STAT3/Girdin/Akt 信号通路。
T3697	3',6-Disinapoylsucrose Disinapoyl sucrose,3,6'-Disinapoyl sucrose,3,6'-二芥子酰基蔗糖	BCL; Epigenetic Reader Domain	Apoptosis; Chromatin/Epigenetic
	3',6-Disinapoylsucrose (Disinapoyl sucrose) 是远志的指标成分，表现出显著的抗氧化活性和抗抑郁效果。
T6648	Rotundine Gindarine,L-Tetrahydropalmatine,Caseanine,罗通定,(-)-Tetrahydropalmatine	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Rotundine (Gindarine) 是多巴胺D1、D2和D3受体的拮抗剂，IC50值分别为 166、1.4 和 3.3 μM。它也是5-HT1A 的拮抗剂，IC50值为 370 nM。
T6S0722	Isoorientin Homoorientin,Luteolin-6-C-glucoside,异荭草苷;异荭草素,异荭草素	Antioxidant; COX	Immunology/Inflammation; Neuroscience; oxidation-reduction
	Isoorientin (Homoorientin) 是一种 COX-2抑制剂，IC50值为 39 μM，具有抗氧化活性。
TN2058	Persicogenin	Anti-infection	Microbiology/Virology
	Persicogenin 是分离自 Rhus retinorrhoea 中，具有抗癌作用。
T6S1101	Astragalin Kaempferol 3-D-glucoside,Kaempferol 3-O-glucoside,kaempferol-3-glucoside,3-Glucosylkaempferol,Astragaline,紫云英苷,Kaempferol 3-β-D-glucopyranoside	Apoptosis; NF-κB	Apoptosis; NF-κB
	Astragalin (Kaempferol 3-O-glucoside) 是一种具有生物活性的天然黄酮类化合物。它具有多种药理特性，包括抗氧化、抗炎、抗癌、神经保护和心脏保护特性。
T4S0295	Apigenin 7-glucoside 波斯菊,Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,芹甙元-7-葡萄糖苷,Thalictiin,Apigetrin	Reactive Oxygen Species; HIV Protease	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Apigenin 7-glucoside (Cosmosiin) 是一种 ROS 清除剂，具有抗增殖、抗氧化作用。
T40832	Ferulic acid acyl-β-D-glucoside Ferulic acid glucoside,Ferulic acid acyl-β-D-glucoside
	Ferulic acid acyl-β-D-glucoside, a metabolite of Ferulic Acid, is a novel inhibitor of fibroblast growth factor receptor 1 (FGFR1). It exhibits IC50 values of 3.78 µM and 12.5 µM for FGFR1 and FGFR2, respectively.
TN4978	Scutellarein-7-O-glucoside	MMP	Proteases/Proteasome
	Scutellarein-7-O-glucoside inhibites MMP-2 activity.
TN4229	Humulene epoxide II	Antifection	Microbiology/Virology
	Humulene epoxide II has antimalarial activity.

天然产物

(20R)-Ginsenoside Rh1

Cat.No: T3793

Synonym: 20(R)-Ginsenoside Rh1,人参皂苷 R-RH1,人参皂苷R-RH1

Target: Others

Sinapine thiocyanate

Cat.No: T3392

Target: P-gp, AChE

Phenylpyruvic acid

Cat.No: T5251

Synonym: 2-Oxo-3-phenylpropanoic acid,3-Phenylpyruvic acid,苯丙酮酸

Target: Others, Endogenous Metabolite

(-)-Isocorypalmine

Cat.No: TQ0176

Synonym: Tetrahydrocolumbamine,(-)-异延胡索单酚碱,(S)-Tetrahydrocolumbamine

Target: Dopamine Receptor, Antifungal

Orcinol glucoside

Cat.No: T2771

Synonym: Sakakin,苔黑酚葡萄糖苷

Target: Antioxidant

Cat.No: T2S2109

Synonym: beta-Fagarine,Skimmianin,茵芋碱,Chloroxylonine,Skimmiamine

Target: Others

Cat.No: T4813

Target: Endogenous Metabolite

2,6-Dimethoxybenzoic acid

Cat.No: T3758

Target: Others, Endogenous Metabolite

D-Glucuronic acid

Cat.No: TJO2758

Synonym: D-葡萄糖醛酸,Aldehydo-D-Glucuronic Acid

Target: Others, Endogenous Metabolite

Cat.No: T2789

Synonym: 黄岑素,野黄芩苷,Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide

Target: Akt, HIV Protease, STAT

3',6-Disinapoylsucrose

Cat.No: T3697

Synonym: Disinapoyl sucrose,3,6'-Disinapoyl sucrose,3,6'-二芥子酰基蔗糖

Target: BCL, Epigenetic Reader Domain

Cat.No: T6648

Synonym: Gindarine,L-Tetrahydropalmatine,Caseanine,罗通定,(-)-Tetrahydropalmatine

Target: Dopamine Receptor, 5-HT Receptor

Cat.No: T6S0722

Synonym: Homoorientin,Luteolin-6-C-glucoside,异荭草苷;异荭草素,异荭草素

Target: Antioxidant, COX

Cat.No: TN2058

Target: Anti-infection

Cat.No: T6S1101

Synonym: Kaempferol 3-D-glucoside,Kaempferol 3-O-glucoside,kaempferol-3-glucoside,3-Glucosylkaempferol,Astragaline,紫云英苷,Kaempferol 3-β-D-glucopyranoside

Target: Apoptosis, NF-κB

Apigenin 7-glucoside

Cat.No: T4S0295

Synonym: 波斯菊,Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,芹甙元-7-葡萄糖苷,Thalictiin,Apigetrin

Target: Reactive Oxygen Species, HIV Protease

Ferulic acid acyl-β-D-glucoside

Cat.No: T40832

Synonym: Ferulic acid glucoside,Ferulic acid acyl-β-D-glucoside

Scutellarein-7-O-glucoside

Cat.No: TN4978

Target: MMP

Humulene epoxide II

Cat.No: TN4229

Target: Antifection

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