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Search Results for " upar "

Targets Recommended: Others

16

抑制剂 & 化合物

10

天然产物

13

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T77412	Lupartumab BAY 1112623	Others	Others
	Lupartumab (BAY 1112623) 是一种抗 LYPD3 (C4.4A) 单克隆抗体，可用于合成抗体-活性分子偶联物，可用于研究与 LYPD3 相关的肿瘤疾病。
T4269	Buparvaquone 布帕伐醌,Butalex,BW 720C	Antibiotic; Parasite	Microbiology/Virology
	Buparvaquone (BW 720C) 是与parvaquone 和atovaquone 有关的一种羟基萘醌类抗原虫药。
T61932	Nesuparib JPI-547/OCN-201	PARP; Wnt/beta-catenin	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Stem Cells
	Nesuparib (JPI-547/OCN-201) 是一种有效的PARP抑制剂，对PARP 和TNKS1具有抑制作用。Nesuparib 具有抗肿瘤活性，可用于治疗肿瘤、内分泌与代谢疾病、泌尿生殖系统疾病，可用于研究神经性疼痛、神经退行性疾病和心血管疾病。
T1827	Buparlisib BKM120,布帕尼西,NVP-BKM120	Apoptosis; PI3K	Apoptosis; PI3K/Akt/mTOR signaling
	Buparlisib (BKM120) 是一种具有口服生物利用度的泛 I 类 PI3K 特异性口服抑制剂，对p110α/p110β/p110δ/p110γ的IC50分别为 52 nM/166 nM/116 nM/262 nM。
T77565	Fluparoxan hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Fluparoxan hydrochloride 是一种高度选择性和有效的α2-肾上腺素受体拮抗剂，可用于预防、改善或治疗神经发育障碍和神经退行性疾病。
T77566	(3aR,9aR)-Fluparoxan	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	(3aR,9aR)-Fluparoxan 是一种高度选择性和有效的肾上腺素能受体α2B 拮抗剂，可用于预防、改善或治疗神经发育障碍和神经退行性疾病。
T27340	Fluparoxan HCl GR50360,GR 50360,Fluparoxan hydrochloride,GR-50360A,GR-50360
	Fluparoxan is a potent α2-adrenergic receptor antagonist (pKB = 7.9) with excellent α2/α1 selectivity (2630 fold).
T70785	Mefuparib Free Base
	Mefuparib Free Base is a potent, highly selective, competitive PARP1/2 inhibitor with IC50 of 3.2/1.9 nM, respectively. Mefuparib (CVL218), has been shown to have promising antiviral activity against the virus that causes COVID-19.
T11992	Mefuparib hydrochloride MPH	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Mefuparib hydrochloride induces apoptosis and possesses prominent anticancer activity in vitro and in vivo. Mefuparib hydrochloride (MPH) is an orally active, substrate-competitive and selective PARP1/2 inhibitor with IC50s of 3.2 nM and 1.9 nM, respectively.
T16365	Buparlisib Hydrochloride NVP-BKM120 Hydrochloride,BKM120 Hydrochloride	Others	Others
	Buparlisib Hydrochloride is an inhibitor of pan-class I PI3K (IC50: 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively).
T80918	Tuparstobart Incagn-02385
	Tuparstobart (Incagn-02385)为针对LAG-3的IgG1κ抗体。LAG-3，作为一种免疫检查点受体蛋白，其主要存在于活化T细胞、NK细胞、B细胞及浆细胞树突细胞上。
T68074	fluparoxan
	Fluparoxan 是一种高选择性和有效的α 2-肾上腺素受体拮抗剂。
T11666	IPR-803	Serine/threonin kinase	Cell Cycle/Checkpoint; Metabolism
	IPR-803 是一种有效的 uPAR·uPA 蛋白-蛋白相互作用抑制剂，具有抗肿瘤活性。 IPR-803 直接与 uPAR 结合，Ki 为 0.2 μM。
TP2338L	Cenupatide acetate Cenupatide acetate(1006388-38-0 Free base)	Others	Others
	Cenupatide acetate 是一种尿激酶纤溶酶原激活物受体 (uPAR) 抑制剂，用于治疗与细胞迁移改变相关的疾病，例如癌症。
T26629	Angstrom6 A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide	PAI-1	Metabolism
	Angstrom6 (A-6 peptide) 是一种从单链尿激酶纤溶酶原激活剂(scuPA)中提取的 8 肽，它能干扰 uPA/uPAR 级联反应并抑制下游效应。Angstrom6 具有抗肿瘤活性，能通过与 CD44 结合并调节 CD44 介导的细胞信号传导，抑制肿瘤细胞的迁移、侵袭和转移。
TP2338	Cenupatide UPARANT,Cenupatide trifluoroacetic acid salt,Ac-Arg-Aib-Arg-α(Me)Phe-NH2)
	Cenupatide is a urokinase plasminogen activator receptor (uPAR) inhibitor. Cenupatide inhibits uPAR binding to the formyl peptide receptors (FPRs) can improve kidney lesions in a rat model of STZ-induced diabetes. Cenupatide reverted STZ-induced up-regula

化合物

Cat.No: T77412

Synonym: BAY 1112623

Target: Others

Cat.No: T4269

Synonym: 布帕伐醌,Butalex,BW 720C

Target: Antibiotic, Parasite

Cat.No: T61932

Synonym: JPI-547/OCN-201

Target: PARP, Wnt/beta-catenin

Cat.No: T1827

Synonym: BKM120,布帕尼西,NVP-BKM120

Target: Apoptosis, PI3K

Fluparoxan hydrochloride

Cat.No: T77565

Target: Adrenergic Receptor

(3aR,9aR)-Fluparoxan

Cat.No: T77566

Target: Adrenergic Receptor

Cat.No: T27340

Synonym: GR50360,GR 50360,Fluparoxan hydrochloride,GR-50360A,GR-50360

Mefuparib Free Base

Cat.No: T70785

Mefuparib hydrochloride

Cat.No: T11992

Synonym: MPH

Target: PARP

Buparlisib Hydrochloride

Cat.No: T16365

Synonym: NVP-BKM120 Hydrochloride,BKM120 Hydrochloride

Target: Others

Cat.No: T80918

Synonym: Incagn-02385

Cat.No: T68074

Cat.No: T11666

Target: Serine/threonin kinase

Cenupatide acetate

Cat.No: TP2338L

Synonym: Cenupatide acetate(1006388-38-0 Free base)

Target: Others

Cat.No: T26629

Synonym: A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide

Target: PAI-1

Cat.No: TP2338

Synonym: UPARANT,Cenupatide trifluoroacetic acid salt,Ac-Arg-Aib-Arg-α(Me)Phe-NH2)

Cat. No.	Product Name	Target	Signaling Pathways
TN6762	(+)-Cuparene	Others	Others
	(+)-Cuparene 是一种生物活性化学品。
TN3469	Aucuparin 2,6-dimethoxy-4-phenylphenol	NADPH-oxidase	Immunology/Inflammation
	Aucuparin (2,6-dimethoxy-4-phenylphenol) 是一种植物抗菌素，具有抗炎活性。在博来霉素 (BLM) 诱导的肺纤维化小鼠模型中，Aucuparin 抑制肺纤维化。在经ABTS 和FRAP 测定显示出明显的清除活性。 Aucuparin 对fmlp 诱导的人中性粒细胞产生超氧化物具有明显的抑制作用，其IC50为17.0μM。
TN5160	trans-2,3-Dihydro-3-ethoxyeuparin	Others	Others
	trans-2,3-Dihydro-3-ethoxyeuparin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5160，CAS号为 1015698-14-2。
TN5161	trans-2,3-Dihydro-3-hydroxyeuparin	Others	Others
	trans-2,3-Dihydro-3-hydroxyeuparin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5161，CAS号为 64185-57-5。
T81653	Noraucuparin
	Noraucuparin是从Sorbus pohuashanensis的叶子中分离得到的联苯型植物抗毒素，具有抗真菌作用。
TN4036	Euparone	Others	Others
	Euparone is a benzofuran from Ruscus aculeatus L..
TN2596	12-Hydroxy-2,3-dihydroeuparin	Others	Others
	12-Hydroxy-2,3-dihydroeuparin是一种天然产物，属于菊科泽兰属，其产品编号为 TN2596，CAS号为 68776-42-1。12-Hydroxy-2,3-dihydroeuparin可用作对照参考。
TN2693	2,3-Dihydro-12,13-dihydroxyeuparin	Others	Others
	2,3-Dihydro-12,13-dihydroxyeuparin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2693，CAS号为 135531-75-8。
TN4258	Isocuparenal	Others	Others
	Isocuparenal 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4258，CAS号为 16982-01-7。
TN1632	Euparin	Antifection	Microbiology/Virology
	Euparin exhibits a moderate antioxidant activity, it also exhibits antifungal activity against Trichophyton mentagrophytes. Euparin has antiviral activity, it exerts its effect during the early events of the replication cycle, from the virus adsorption to

天然产物

Cat.No: TN6762

Target: Others

Cat.No: TN3469

Synonym: 2,6-dimethoxy-4-phenylphenol

Target: NADPH-oxidase

trans-2,3-Dihydro-3-ethoxyeuparin

Cat.No: TN5160

Target: Others

trans-2,3-Dihydro-3-hydroxyeuparin

Cat.No: TN5161

Target: Others

Cat.No: T81653

Cat.No: TN4036

Target: Others

12-Hydroxy-2,3-dihydroeuparin

Cat.No: TN2596

Target: Others

2,3-Dihydro-12,13-dihydroxyeuparin

Cat.No: TN2693

Target: Others

Cat.No: TN4258

Target: Others

Cat.No: TN1632

Target: Antifection

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01257	uPAR/PLAUR Protein, Mouse, Recombinant (His) uPAR,Cd87,u-PAR,plasminogen activator, urokinase re...	Mouse	HEK293 Cells
	uPAR/PLAUR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.4 kDa and the accession number is P35456-1.
TMPY-02141	uPAR/PLAUR Protein, Human, Recombinant (His) UPAR,CD87,plasminogen activator, urokinase receptor...	Human	HEK293 Cells
	uPAR/PLAUR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.8 kDa and the accession number is Q03405-1.
TMPY-01017	uPAR/PLAUR Protein, Mouse, Recombinant (His & hFc) plasminogen activator, urokinase receptor,u-PAR,uPAR	Mouse	HEK293 Cells
	uPAR/PLAUR Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 58 kDa and the accession number is P35456-1.
TMPK-00228	uPAR/PLAUR Protein, Human, Recombinant (hFc) U-PAR,PLAUR,uPAR,MO3,CD87	Human	HEK293 Cells
	The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR. uPAR/PLAUR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 58.2 kDa and the accession number is Q03405-1.
TMPK-01175	uPAR/PLAUR Protein, Cynomolgus, Recombinant (His) U-PAR,UPAR,MO3,CD87,PLAUR	Cynomolgus	HEK293 Cells
	The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR. uPAR/PLAUR Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 32.69 kDa and the accession number is Q9GK78.
TMPK-00226	uPAR/PLAUR Protein, Human, Recombinant (His & Avi) CD87,uPAR,U-PAR,MO3,PLAUR	Human	HEK293 Cells
	The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR. uPAR/PLAUR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 34.36 kDa and the accession number is Q03405-1.
TMPK-00227	uPAR/PLAUR Protein, Human, Recombinant (His & Avi), Biotinylated CD87,PLAUR,U-PAR,MO3,uPAR	Human	HEK293 Cells
	The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR. uPAR/PLAUR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 34.36 kDa and the accession number is Q03405-1.
TMPK-00216	uPAR/PLAUR Protein, Mouse, Recombinant (His & Avi), Biotinylated U-PAR,PLAUR,MO3,CD87,uPAR	Mouse	HEK293 Cells
	The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR. uPAR/PLAUR Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 32.92 kDa and the accession number is P35456-1.
TMPK-00215	uPAR/PLAUR isoform 1 Protein, Mouse, Recombinant (His & Avi) CD87,UPAR,PLAUR,MO3,U-PAR	Mouse	HEK293 Cells
	The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR. uPAR/PLAUR isoform 1 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 32.92 kDa and the accession number is P35456-1.
TMPH-03397	uPAR/PLAUR Protein, Rat, Recombinant (His)	Rat	E. coli
	Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. uPAR/PLAUR Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.1 kDa and the accession number is P49616.
TMPK-01225	MRC2 Protein, Human, Recombinant (His) C-type lectin domain family 13 member E, Endocytic receptor ...	Human	HEK293 Cells
	MRC2 (Mannose Receptor C Type 2) is a constitutively recycling endocytic receptor belonging to the mannose receptor family, which has been found to be closely involved with cancer metastasis. MRC2 expresses an extracellular fibronectin type II domain that binds to and internalizes collagen, suggesting that it may play a role in modulating renal fibrosis. MRC2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.64 kDa and t...
TMPJ-00541	CD177 Protein, Human, Recombinant (His) PRV-1,HNA-2a,Human Neutrophil Alloantigen 2a,CD177,Polycythe...	Human	HEK293 Cells
	CD177 is polymorphic and has at least two alleles: PRV1 and NB1. Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors. PRV1 is expressed by neutrophils and neutrophil precursors,and changes in expression serve as diagnostic markers for myeloproliferative disorders such as polycythemia vera and essential thrombocythemia. PRV1 may also be expressed by Erythroblasts, B cells, and Monocytes. NB1, a Glycosyl-Phospha...
TMPJ-00709	LY6H Protein, Human, Recombinant (His) Ly-6H,LY6H,Lymphocyte Antigen 6H	Human	HEK293 Cells
	Lymphocyte Antigen 6H (LY6H) is a novel member of the LY6 family of glycosylphosphatidylinositol-anchored cell surface glycoproteins. LY6H contains one UPAR/Ly6 domain. Human LY6H is synthesized as a 140 amino acid precursor that contains a 25 amino acid signal sequence, 20 amino acid propeptide that is removed in the mature form, and a 90 amino acid mature chain. LY6H is highly expressed in the brain (cerebral cortex, amygdala, hippocampus and subthalamic nucleus) and in acute human leukemic ce...

重组蛋白

uPAR/PLAUR Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01257

Species: Mouse

Expression System: HEK293 Cells

uPAR/PLAUR Protein, Human, Recombinant (His)

Cat.No: TMPY-02141

Species: Human

Expression System: HEK293 Cells

uPAR/PLAUR Protein, Mouse, Recombinant (His & hFc)

Cat.No: TMPY-01017

Species: Mouse

Expression System: HEK293 Cells

uPAR/PLAUR Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00228

Species: Human

Expression System: HEK293 Cells

uPAR/PLAUR Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01175

Species: Cynomolgus

Expression System: HEK293 Cells

uPAR/PLAUR Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00226

Species: Human

Expression System: HEK293 Cells

uPAR/PLAUR Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00227

Species: Human

Expression System: HEK293 Cells

uPAR/PLAUR Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00216

Species: Mouse

Expression System: HEK293 Cells

uPAR/PLAUR isoform 1 Protein, Mouse, Recombinant (His & Avi)

Cat.No: TMPK-00215

Species: Mouse

Expression System: HEK293 Cells

uPAR/PLAUR Protein, Rat, Recombinant (His)

Cat.No: TMPH-03397

Species: Rat

Expression System: E. coli

MRC2 Protein, Human, Recombinant (His)

Cat.No: TMPK-01225

Species: Human

Expression System: HEK293 Cells

CD177 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00541

Species: Human

Expression System: HEK293 Cells

LY6H Protein, Human, Recombinant (His)

Cat.No: TMPJ-00709

Species: Human

Expression System: HEK293 Cells

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