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15

抑制剂 & 化合物

17

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T35918	N-Arachidonoyl Taurine
	N-Arachidonoyl taurine is an arachidonoyl amino acid. It is oxygenated by 12(S)- and 15(S)-lipoxygenase and is converted to 12-HETE-taurine (12-HETE-T) in murine resident peritoneal macrophages. N-Arachidonoyl taurine is an activator of the transient receptor potential vanilloid (TRPV) channels TRPV1 and TRPV4 (EC50s = 28 and 21 μM, respectively). It increases calcium flux in HIT-T15 pancreatic β-cells and INS-1 rat islet cells when used at a concentration of 10 μM and increases insulin secretio...
T32602	Laurylsarcosyltaurine Lauryl-sar-taurine
	Laurylsarcosyltaurine is a surface active constituent of crab gastric juice.
T34788	Taurolithocholic acid Lithocholyltaurine,Lithocholic acid taurine conjugate
	Taurolithocholic acid is a cholagogue and choleretic.
T83858	Tauro-Obeticholic Acid sodium Tauro-6-Ethylchenodeoxycholic Acid,Tauro-6-Ethyl-CDCA,Obeticholic Acid Taurine Conjugate,Tauro-OCA,T-ECDCA
	陶氏奥贝胆酸是奥贝胆酸的活性代谢物，属于法尼索德X受体(FXR)激动剂并且是熊脱氧胆酸的半合成衍生物。陶氏奥贝胆酸通过在肝脏中与牛磺酸结合形成，但可以通过肠道微生物被再次转换回奥贝胆酸。
T25455L	Glutaurine aceate	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	含有谷氨酰胺和牛磺酸残基的 Glutaurine aceate 是甲状旁腺的一种口服活性激素。Glutaurine 作为一种激素，从甲状旁腺嗜氧细胞中分离出来。Glutaurine 可用于抗癫痫和抗遗忘的研究。
T77991	Glutaurine TFA Litoralon TFA
	Glutaurine (Litoralon) TFA，含谷氨酰胺与牛磺酸残基，为甲状旁腺源嗜氧细胞分离的口服活性激素。该化合物在抗癫痫与抗健忘症研究中有应用。
T124470	N-Glyceryltaurine
	N-Glyceryltaurine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124470。
T126442	N-Methyltaurine
	N-Methyltaurine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126442，CAS号为 107-68-6。
T33878	Pantoyltaurine NSC 122022,NSC 3086,NSC3086,NSC-3086
	Pantoyltaurine is a biochemical.
T65644	N-Cyclohexyltaurine
	N-Cyclohexyltaurine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65644，CAS号为 103-47-9。
T7533	Taurolidine	Apoptosis; Others; Antibacterial; Antibiotic	Apoptosis; Microbiology/Virology; Others
	Taurolidine 是一种广谱抗菌剂，用于预防中心静脉导管相关感染。它具有抗真菌和抗肿瘤作用。
T13758	LS2265	Others	Others
	LS2265, a fenofibrate derivative with a taurine modification, effectively induces the proliferation of peroxisomes in rat liver cells.
T37416	Tauro-α-muricholic Acid (sodium salt)
	Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary bile acid α-muricholic acid . TαMCA is common in rodents but has also been found in small amounts in human serum.
T37846	Taurohyocholic Acid (sodium salt)
	Taurohyocholic acid (THCA) is a taurine-conjugated form of the porcine-specific primary bile acid hyocholic acid .1THCA inhibits precipitation of cholesterol crystals by stabilizing cholesterol in the liquid-crystalline phase.2It prevents cholestasis and cellular necrosis induced by taurolithocholic acid in isolated rat livers.3THCA levels are increased in the urine of patients with hepatitis B-induced cirrhosis.4
T21783	AG-183
	(Z)-Tyrphostin A51 是 Lanoconazole A51 的 Z 构型形式。Tyrphostin A51 是一种有效的蛋白酪氨酸激酶 (PTK)抑制剂，以剂量依赖性方式抑制原代星形胶质细胞培养物中 [3H]牛磺酸的体积敏感释放。Tyrphostin A51 显着降低细胞酪氨酰磷酸化水平。Tyrphostin A51 抑制基础和 EGF 诱导的人骨细胞增殖。

化合物

N-Arachidonoyl Taurine

Cat.No: T35918

Laurylsarcosyltaurine

Cat.No: T32602

Synonym: Lauryl-sar-taurine

Taurolithocholic acid

Cat.No: T34788

Synonym: Lithocholyltaurine,Lithocholic acid taurine conjugate

Tauro-Obeticholic Acid sodium

Cat.No: T83858

Synonym: Tauro-6-Ethylchenodeoxycholic Acid,Tauro-6-Ethyl-CDCA,Obeticholic Acid Taurine Conjugate,Tauro-OCA,T-ECDCA

Glutaurine aceate

Cat.No: T25455L

Target: Thyroid hormone receptor(THR)

Cat.No: T77991

Synonym: Litoralon TFA

N-Glyceryltaurine

Cat.No: T124470

N-Methyltaurine

Cat.No: T126442

Cat.No: T33878

Synonym: NSC 122022,NSC 3086,NSC3086,NSC-3086

N-Cyclohexyltaurine

Cat.No: T65644

Cat.No: T7533

Target: Apoptosis, Others, Antibacterial, Antibiotic

Cat.No: T13758

Target: Others

Tauro-α-muricholic Acid (sodium salt)

Cat.No: T37416

Taurohyocholic Acid (sodium salt)

Cat.No: T37846

Cat.No: T21783

Cat. No.	Product Name	Target	Signaling Pathways
T0022	Taurine 牛磺酸,2-Aminoethanesulfonic acid	LDL; Endogenous Metabolite; Autophagy	Autophagy; Metabolism
	Taurine (2-Aminoethanesulfonic acid) 是一种含硫氨基酸的有机渗透剂，为胆汁盐的形成提供底物，并在调节细胞内游离钙浓度方面发挥作用，有激活脂肪细胞自噬的能力。
T2963	Cholic Acid Cholanic acid,胆汁酸,Cholate,Colalin	Endogenous Metabolite	Metabolism
	Cholic Acid (Cholate) 是肝脏产生的主要胆汁酸，与牛磺酸或甘氨酸缀合，有助于脂肪吸收和胆固醇排泄。
T4537	Cholic acid sodium 胆酸钠,[胆酸钠],SodiumCholate	HIV Protease; Endogenous Metabolite	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Cholic acid sodium (SodiumCholate) 是肝脏中产生的主要胆汁酸，通常与牛磺酸或甘氨酸结合，有助于脂肪吸收和胆固醇排泄。
T2O2721	L-Cysteine Thioserine,L-半胱氨酸,cysteine,半胱氨酸,L-(+)-Cysteine	Endogenous Metabolite	Metabolism
	L-Cysteine (L-(+)-Cysteine) 是人体非必需的含硫氨基酸。L-Cysteine 对蛋白质合成、解毒和多种代谢功能很重要。L-Cysteine 存在于指甲、皮肤和头发的主要蛋白质-角蛋白中，对胶原蛋白的生成、皮肤弹性和质地都很重要。L-Cysteine 是抗氧化剂谷胱甘肽的一种成分，在辅酶A、肝素和生物素等基本生化物质的代谢中起着重要作用，也是氨基酸牛磺酸的制造所必需的。
T21615	Guanidinoethyl sulfonate 脒基牛磺酸,Taurocyamine	Chloride channel	Membrane transporter/Ion channel
	Guanidinoethyl sulfonate (Taurocyamine) 它是一种牛磺酸的结构类似物，也是牛磺酸转运的竞争性拮抗剂。它能够诱导怀孕大鼠排泄含有大量牛磺酸的尿液，导致组织中牛磺酸含量降低，从而容易产生牛磺酸缺乏的胎鼠。
T5225	Hypotaurine 2-Aminoethanesulfinic acid,亚牛磺酸,2-Aminoethylsulfinic acid	Chloride channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	Hypotaurine (2-Aminoethanesulfinic acid) 是星形胶质细胞中半胱氨酸生物合成的牛磺酸中间体，是甘氨酸受体 (glycine receptor) 的内源性抑制性氨基酸。Hypotaurine 也是抗氧化剂。
T5213	Acetyl phosphate(lithium potassium) 乙酰磷酸锂钾盐,Lithium potassium acetyl phosphate,Acetylphosphoric acid	Others; Endogenous Metabolite	Metabolism; Others
	Acetyl phosphate lithium potassium (Lithium potassium acetyl phosphate) 是内源性代谢产物的一种。
TN5283	L-Cysteine hydrochloride hydrate L-Cysteine hydrochloride monohydrate,L-半胱氨酸盐酸盐一水物,L-半胱氨酸盐酸盐一水合物	Others; Endogenous Metabolite	Metabolism; Others
	L-Cysteine hydrochloride hydrate (L-Cysteine hydrochloride monohydrate) 是条件必需氨基酸，是硫化氢、谷胱甘肽和牛磺酸等生物活性分子的前体。它可以抑制胃饥饿素，抑制啮齿动物和人类的食欲。
T2965	Deoxycholic acid Cholorebic,去氧胆酸,脱氧胆酸,Deoxycholate,Desoxycholic acid,Cholanoic Acid,Cholerebic	Endogenous Metabolite; GPCR19	GPCR/G Protein; Metabolism
	Deoxycholic acid (Cholanoic Acid) 是 G 蛋白偶联胆汁酸受体 TGR5的激活剂。
T5303	Isethionic acid sodium salt Sodium isethionate,羟乙基磺酸钠	Others; Endogenous Metabolite	Metabolism; Others
	Isethionic acid sodium salt (Sodium isethionate) 是内源性代谢产物的一种。
T0847	Chenodeoxycholic acid CDCA,鹅去氧胆酸,Chenodiol	Potassium Channel; FXR; Endogenous Metabolite; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism
	Chenodeoxycholic acid (CDCA) 是一种胆汁酸，通常与甘氨酸或牛磺酸结合。它作为清洁剂溶解脂肪以供肠道吸收，并被小肠重新吸收。它被用作利胆剂、利胆泻药，以及预防或溶解胆结石。
T1138	Taurocholic acid sodium salt hydrate 牛胆酸钠,牛磺胆酸钠水合物,Sodium taurocholate hydrate,Taurocholic Acid sodium hydrate	Others; Potassium Channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism; Others
	Taurocholic acid sodium salt hydrate (Sodium taurocholate hydrate) 是一种胆汁酸钠盐水合物，作用是参与脂肪的乳化。
T2202	Lithocholic acid 3α-Hydroxy-5β-cholanic acid,石胆酸	Apoptosis; Others; FXR; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Metabolism; Others
	Lithocholic acid (3α-Hydroxy-5β-cholanic acid) 是由鹅去氧胆酸盐通过细菌作用形成的胆汁酸，通常与甘氨酸或牛磺酸结合，被用作利胆剂。它作为清洁剂溶解脂肪以供吸收，并且本身被吸收。
T75319	Taurodeoxycholic acid Taurodeoxychloic acid	Apoptosis; Calcium Channel; Caspase	Apoptosis; Membrane transporter/Ion channel; Metabolism; Proteases/Proteasome
	Taurodeoxycholic acid (Taurodeoxychloic acid) 是脱氧胆酸的胆汁酸牛磺酸共轭物，是一种人体代谢物，可稳定线粒体膜，减少自由基形成。Taurodeoxycholic acid 通过阻断钙介导的凋亡通路以及 Caspase-12 激活来抑制凋亡 (apoptosis)。Taurodeoxycholic acid具有神经保护活性，可用于研究 3-硝基丙酸诱导或稳定遗传的亨廷顿舞蹈病 (HD) 。
T75427	Cholic acid sodium hydrate
	Cholic acid sodium hydrate, 为肝脏主要产生的胆汁酸，常与甘氨酸或牛磺酸结合，促进脂肪吸收及胆固醇排出，具备口服活性。
T37997	Murideoxycholic Acid
	Murideoxycholic acid (MDCA) is a secondary bile acid produced from α-muricholic acid and β-muricholic acid.[1] It is also a metabolite of lithocholic acid in liver S9 fractions from humans and other species.[2] MDCA prevents gallstone formation in hamsters fed a lithogenic diet but does not resolve gallstones in prairie dogs fed a high cholesterol diet.[3],[4] Gallstones formed during MDCA administration after a high cholesterol diet are comprised of an insoluble calcium salt of murideoxycholyl ...
T37770	Taurohyodeoxycholic acid
	Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid .1THDCA decreases the size and weight of human gallstonesin vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats.2Co-administration of THDCA with taurochenodeoxycholic acid prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats.3THDCA also reduces myeloperoxidase activity, expressi...

天然产物

Cat.No: T0022

Synonym: 牛磺酸,2-Aminoethanesulfonic acid

Target: LDL, Endogenous Metabolite, Autophagy

Cat.No: T2963

Synonym: Cholanic acid,胆汁酸,Cholate,Colalin

Target: Endogenous Metabolite

Cholic acid sodium

Cat.No: T4537

Synonym: 胆酸钠,[胆酸钠],SodiumCholate

Target: HIV Protease, Endogenous Metabolite

Cat.No: T2O2721

Synonym: Thioserine,L-半胱氨酸,cysteine,半胱氨酸,L-(+)-Cysteine

Target: Endogenous Metabolite

Guanidinoethyl sulfonate

Cat.No: T21615

Synonym: 脒基牛磺酸,Taurocyamine

Target: Chloride channel

Cat.No: T5225

Synonym: 2-Aminoethanesulfinic acid,亚牛磺酸,2-Aminoethylsulfinic acid

Target: Chloride channel, Endogenous Metabolite

Acetyl phosphate(lithium potassium)

Cat.No: T5213

Synonym: 乙酰磷酸锂钾盐,Lithium potassium acetyl phosphate,Acetylphosphoric acid

Target: Others, Endogenous Metabolite

L-Cysteine hydrochloride hydrate

Cat.No: TN5283

Synonym: L-Cysteine hydrochloride monohydrate,L-半胱氨酸盐酸盐一水物,L-半胱氨酸盐酸盐一水合物

Target: Others, Endogenous Metabolite

Deoxycholic acid

Cat.No: T2965

Synonym: Cholorebic,去氧胆酸,脱氧胆酸,Deoxycholate,Desoxycholic acid,Cholanoic Acid,Cholerebic

Target: Endogenous Metabolite, GPCR19

Isethionic acid sodium salt

Cat.No: T5303

Synonym: Sodium isethionate,羟乙基磺酸钠

Target: Others, Endogenous Metabolite

Chenodeoxycholic acid

Cat.No: T0847

Synonym: CDCA,鹅去氧胆酸,Chenodiol

Target: Potassium Channel, FXR, Endogenous Metabolite, Autophagy

Taurocholic acid sodium salt hydrate

Cat.No: T1138

Synonym: 牛胆酸钠,牛磺胆酸钠水合物,Sodium taurocholate hydrate,Taurocholic Acid sodium hydrate

Target: Others, Potassium Channel, Endogenous Metabolite

Lithocholic acid

Cat.No: T2202

Synonym: 3α-Hydroxy-5β-cholanic acid,石胆酸

Target: Apoptosis, Others, FXR, Endogenous Metabolite, Autophagy

Taurodeoxycholic acid

Cat.No: T75319

Synonym: Taurodeoxychloic acid

Target: Apoptosis, Calcium Channel, Caspase

Cholic acid sodium hydrate

Cat.No: T75427

Murideoxycholic Acid

Cat.No: T37997

Taurohyodeoxycholic acid

Cat.No: T37770

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