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Search Results for " rama "

Targets Recommended: Potassium Channel Calcium Channel GABA Receptor Sodium Channel GluR Carbonic Anhydrase iGluR

15

抑制剂 & 化合物

1

天然产物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T0675	Topiramate RWJ 17021,McN 4853,托吡酯	Potassium Channel; Calcium Channel; GABA Receptor; Sodium Channel; GluR; Carbonic Anhydrase; iGluR	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Topiramate (RWJ 17021) 是一种GluR5受体拮抗剂，可通过增强GABAergic 活性，抑制kainate/AMPA 受体，抑制钠和钙通道的电压敏感，增加钾电导并抑制碳酸酐酶来产生抗癫痫作用，用于治疗部分性和全身性癫痫发作。
T6277	Doramapimod BIRB 796,达马莫德,度马莫德	Raf; p38 MAPK; Autophagy	Autophagy; MAPK
	Doramapimod (BIRB 796) 是一种具有口服活性的p38 MAPK 抑制剂，Kd 值为0.1nM。它也抑制B-Raf 和 Abl，IC50分别为 83 nM 和 14.6 μM。
T2396	Ramatroban BAY u3405,雷马曲班	GPR; Prostaglandin Receptor; PPAR	DNA Damage/DNA Repair; Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism
	Ramatroban (BAY u3405) 是一种血栓素 A(2) (TxA(2)) 拮抗剂，IC50为 14 nM。它还通过抑制PGD2结合从而拮抗CRTH2，IC50为113 nM。它用于治疗过敏性鼻炎，可用于治疗哮喘的研究。
T83168	Aderamastat FP-003,FP-025	MMP	Proteases/Proteasome
	Aderamastat (FP-025) 是一种具有口服活性的基质金属蛋白酶12（MMP-12）抑制剂，适用于过敏性哮喘、COPD与肺纤维化的研究。
T1588	Idramantone 5-Hydroxy-2-adamantanone,伊决孟酮,Kemantane,伊屈孟酮 (INN)	Others	Others
	Idramantone (Kemantane) 是一种免疫激活剂，是 Adamantane 衍生物。
T8588	Buramate	Antibacterial	Microbiology/Virology
	Buramate 是抗精神病药和抗惊厥药。
T61145	Topiramate lithium
	Topiramate lithium (McN 4853) is a wide-ranging antiepileptic compound with GluR5 receptor antagonistic properties. Its mechanism of action involves enhancing GABAergic activity, inhibiting kainate/AMPA receptors, voltage-sensitive sodium and calcium channels, and increasing potassium conductance. Additionally, this compound inhibits carbonic anhydrase. [1][2][3]
T73233	Ciramadol WY 15705
	Ciramadol (WY 15705) 是一种有效的镇痛剂，具有麻醉激动剂和拮抗剂的特点。Ciramadol (WY 15705) 可用于术后疼痛治疗研究。
T125749	Pramanicin
	Pramanicin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125749。
T26233	Styramate
	Styramate is an anticonvulsant.
T13185	Topiramate D12 RWJ 17021 D12,McN 4853 D12	Others	Others
	Topiramate D12 is a deuterium labeled Topiramate. Topiramate is an agent of broad-spectrum antiepileptic. Topiramate is an antagonist of GluR5 receptor.
T69341	Tramazoline hydrochloride
	Tramazoline hydrochloride is commonly used in nasal spray as a nasal decongestant by acting as an α-adrenergic receptor agonist that inhibits secretion of nasal mucus.
T27315	Fexaramate
	Fexaramate is a potent, selective agonist of farnesoid X receptor.
T71058	Doramapimod HCl
	Doramapimod HCl is the salt form of Doramapimod, a member of the N-pyrazole-N'-naphthly urea class of p38MAPK inhibitors, which binds to the kinase with both slow association and dissociation rates. BIRB -796 has entered clinical trials for the treatment of autoimmune diseases.
T37186	D-(-)-Citramalic Acid (lithium salt)
	D-(-)-Citramalic acid (lithium salt) is a biochemical intermediate involved in the anaerobic metabolism of glutamate through the methylaspartate pathway of C. tetanomorphum. It also plays various roles in other aspects of bacterial metabolism.

化合物

Cat.No: T0675

Synonym: RWJ 17021,McN 4853,托吡酯

Target: Potassium Channel, Calcium Channel, GABA Receptor, Sodium Channel, GluR, Carbonic Anhydrase, iGluR

Cat.No: T6277

Synonym: BIRB 796,达马莫德,度马莫德

Target: Raf, p38 MAPK, Autophagy

Cat.No: T2396

Synonym: BAY u3405,雷马曲班

Target: GPR, Prostaglandin Receptor, PPAR

Cat.No: T83168

Synonym: FP-003,FP-025

Target: MMP

Cat.No: T1588

Synonym: 5-Hydroxy-2-adamantanone,伊决孟酮,Kemantane,伊屈孟酮 (INN)

Target: Others

Cat.No: T8588

Target: Antibacterial

Topiramate lithium

Cat.No: T61145

Cat.No: T73233

Synonym: WY 15705

Cat.No: T125749

Cat.No: T26233

Cat.No: T13185

Synonym: RWJ 17021 D12,McN 4853 D12

Target: Others

Tramazoline hydrochloride

Cat.No: T69341

Cat.No: T27315

Doramapimod HCl

Cat.No: T71058

D-(-)-Citramalic Acid (lithium salt)

Cat.No: T37186

Cat. No.	Product Name	Target	Signaling Pathways
T38981	D-Tetramannuronic acid
	D-Tetramannuronic acid, an alginate oligomer, is derived from marine brown algae and certain Gram negative bacteria. It serves as a valuable compound for pain and vascular dementia research[4].

天然产物

D-Tetramannuronic acid

Cat.No: T38981

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00561	30S ribosomal protein S4 Protein, E. coli, Recombinant (His) Small ribosomal subunit protein uS4,ramA,rpsD,30S r...	E. coli	E. coli
	One of two assembly initiator proteins for the 30S subunit, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; With S5 and S12 plays an important role in translational accuracy; many suppressors of streptomycin-dependent mutants of protein S12 are found in this protein, some but not all of which decrease translational accuracy (ram, ribosomal ambiguity mutations).; Plays a role in mRNA unwinding by the ribosome, possibly by forming part of a processivity c...
TMPY-06924	Scy p 1 Protein, Scylla paramamosain, Recombinant	Scylla paramamosain	E. coli
	Scy p 1 Protein, Scylla paramamosain, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.75 kDa.

重组蛋白

30S ribosomal protein S4 Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00561

Species: E. coli

Expression System: E. coli

Scy p 1 Protein, Scylla paramamosain, Recombinant

Cat.No: TMPY-06924

Species: Scylla paramamosain

Expression System: E. coli

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