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47

抑制剂 & 化合物

15

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T78408	Nicotinamide 1,N6-ethenoadenine dinucleotide ε-NAD
	Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) 是一种NAD的荧光类似物，它可作为底物参与细菌毒素催化的信号转导G蛋白G-ADP核糖基化反应。此外，ε-NAD还常用作ADP核糖基化反应研究的荧光底物。
T83801	ε-NAADP+ sodium Etheno-NAADP,β-Nicotinic Acid-1,N6-Ethenoadenine dinucleotide phosphate,Nicotinic Acid adenine dinucleotide phosphate
	ε-NAADP+是钙动员诱导剂NAADP的荧光衍生物。在海胆卵细胞匀浆中诱导钙释放(EC50 = 5 µM)。ε-NAADP+在275 nm和410 nm分别显示激发/发射峰值，且在DMSO中的相对发射增加了三倍。
T83675	Thio-NAD Thionicotinamide NAD,Thionicotinamide adenine dinucleotide
	Thio-NAD是一种经硫酮改造的信号分子和酶辅因子NAD+的衍生物。它能够在碱性磷酸酶(ALP)酶活性检测中替代NAD+作为辅因子。Thio-NAD被用作双酶循环ELISA的底物，以识别严重急性呼吸综合征冠状病毒2（SARS-CoV-2)刺突糖蛋白，亦称为表面糖蛋白，以及患者痰液中的活M. tuberculosis细菌。其在405 nm处表现出吸收，使其能够与其他辅因子区分开来。
T83800	6-Biotin-17-NAD+ sodium 6-Biotin-17-Nicotinamide adenine dinucleotide,β-Nicotinamide-N6-(2-(6-(6-[biotinyl]aminohexanoyl)aminohexanoyl)aminoethyl)adenine dinucleotide
	6-Biotin-17-NAD+ 是信号分子及酶辅因子NAD+的生物素化衍生物，已应用于高通量筛选(HTS)中，用于测定线粒体复合物I（又称NADH脱氢酶）的活性。
T83799	6-alkyne NAD+ sodium β-Nicotinamide-N6-propargyladenine dinucleotide,6-Parg NAD,6-alkyne Nicotinamide adenine dinucleotide,Click Tag™ 6-alkyne NAD
	6-炔基NAD+是一种可点击的信号分子及酶辅因子NAD+形式。它与荧光标签联用，用于检测聚(ADP-核糖)聚合酶(PARP)蛋白质底物。
T77253	β-Nicotinamide adenine dinucleotide reduced dipotassium
	β-Nicotinamide adenine dinucleotide reduced dipotassium 作为一种口服有效的还原型辅酶，在ADP-核糖基转移酶反应中担任ADP-核糖单元的供体及环状ADP-核糖的前体。该化合物在细胞能量代谢，包含糖酵解、β-氧化及三羧酸(TCA)循环中，发挥重要的再生电子供体角色。
T31261	Deaminocozymase Deamino-NAD,Deamino DPN,Nicotinamide-hypoxanthine dinucleotide,Deamino NAD,Desamino-DPN
	Deaminocozymase also known as Nicotinamide-hypoxanthine dinucleotide, is a biochemical.
T64590	Flavin Adenine Dinucleotide DiSodium Salt xhydrate
	Flavin Adenine Dinucleotide DiSodium Salt xhydrate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64590。
T83798	8-bromo NAD+ sodium 8-bromo Nicotinamide adenine dinucleotide,N(8-bromo-A)D+
	8-bromo NAD+ 作为循环ADP-核糖（cADPR）抑制剂8-bromo cADPR的前药形式，通过CD38转化为8-bromo-cADPR。在1 mM浓度下，8-bromo NAD+ 阻止由N-formyl-Met-Leu-Phe (fMLP) 在分离的小鼠骨髓衍生的中性粒细胞内引起的细胞内钙水平增加和趋化作用。同时，在100 µM浓度下使用，减少了小鼠原代小胶质细胞中LPS诱导的亚硝酸盐产生以及TNF-α和IL-2的分泌。
T83844	8-(2-azidobenzylthio) NAD+ sodium 8-(2-azidobenzylthio) Nicotinamide adenine dinucleotide,Click Tag™ 8-(2-azidobenzylthio) NAD+
	8-(2-azidobenzylthio) NAD+ 是一种可点击形式的信号分子及酶辅因子NAD+。
T83845	8-(4-azidophenacylthio) NAD+ sodium Click Tag™ 8-(4-azidophenacylthio) NAD+,8-(4-azidophenacylthio) Nicotinamide adenine dinucleotide
	8-(4-azidophenacylthio) NAD+ 是NAD+信号分子及酶辅因子的一种可点击形式。
T9137	SN-011 [1,1'-Biphenyl]-4-carboxamide, N-[3-[[(4-fluorophenyl)sulfonyl]amino]-4-hydroxyphenyl]-,GUN35901	STING	Immunology/Inflammation
	SN-011 (GUN35901) 是选择性 STING 抑制剂，可与环状二核苷酸 (CDN) 竞争 STING 二聚体的结合口袋，从而阻断 CDN 结合和 STING 激活。它用于 STING 驱动的自身免疫和炎症性疾病的研究，抑制 STING 信号传导的 IC50值为 76 nM。
T20466	Keto-pantoyllactone 二氢-4,4-二甲基-2,3-呋喃二酮,Keto pantoyllactone,Ketopantoyllactone,Dihydro-4,4-dimethyl-2,3-furandione	Others	Others
	Keto-pantoyllactone (Dihydro-4,4-dimethyl-2,3-furandione) 通过烟酰胺腺嘌呤二核苷酸磷酸的酮泛酰内酯依赖性氧化来测定。
T40686	Tiazofurin NSC 286193,Riboxamide,噻唑呋林	Dehydrogenase	Metabolism
	Tiazofurin (NSC-286193) 是一种合成的核苷类似物，显示出抗肿瘤活性。它在细胞内合成为 tiazole-4-carboxamide adenine dinucleotide (TAD)，TAD 可有效抑制 IMP 脱氢酶。
T33565	NAAD sodium salt NAAD钠盐,NAAD Na salt,Deamido Nad Sodium Salt,NAAD Na, NaAD
	NAAD sodium salt (NAAD Na salt) 是烟酰胺腺嘌呤二核苷酸合酶的底物，可用于研究底物的特异性和动力学。
TP2083L	Ac9-25 acetate Ac9-25 acetate(284040-76-2 free base)	Others	Others
	Ac9-25 acetate 通过 FPR 激活中性粒细胞还原的烟酰胺腺嘌呤二核苷酸磷酸氧化酶。
T7092	NADPH tetrasodium salt	Others; Ferroptosis; Endogenous Metabolite	Apoptosis; Metabolism; Others
	NADPH tetrasodium salt 是电子受体烟酰胺腺嘌呤二核苷酸磷酸的还原形式，在各种生物反应中充当电子供体。NADPH tetrasodium salt 也是一种内源性铁死亡抑制剂。
T9518	Inarigivir ammonium ORI-9020 ammonium,SB-9200 ammonium,Inarigivir铵	HBV	Microbiology/Virology
	Inarigivir ammonium (SB-9200 ammonium) 是一种二核苷酸抗病毒化合物，可显着降低表达乙型肝炎病毒的转基因小鼠的 HBV DNA。它是一种激活细胞内先天免疫的视黄酸诱导基因-I 激动剂。
T1880	P7C3	Others	Others
	P7C3 是一种 aminopropyl carbazole 类化合物，具有口服活性，可透过血脑屏障，具有神经保护作用。它可用于神经退行性疾病，如帕金森病的研究。
T12781	RV01	Others	Others
	RV01 是一种新型的白藜芦醇喹啉取代类似物，可抑制 DNA 损伤，降低乙醇诱导的乙醛脱氢酶 (ALDH2) 的 mRNA 表达，具有清除羟自由基的活性。RV01 降低 iNOS 的表达，具有抗神经炎症作用。RV01降低肿瘤坏死因子-a (TNF-a)和白细胞介素-6 (IL-6) mRNA 水平和分泌，抑制lps 诱导的ROS 生成和烟酰胺腺嘌呤二核苷酸磷酸(NADPH)氧化酶活化，降低toll 样受体4 (TLR4)的蛋白表达，抑制lps 诱导的丝裂原活化蛋白激酶(MAPK)和核转录因子-кB (NF-кB)信号通路的激活。
T11596	IACS-8803	Others	Others
	IACS-8803 is a potent cyclic dinucleotide STING agonist that exhibits strong systemic antitumor efficacy.
T7365	Inarigivir ORI-9020,SB-9000	HBV	Microbiology/Virology
	Inarigivir (ORI-9020) is a dinucleotide that can significantly reduce liver HBV DNA.
T22670	cis-Ned 19	Others	Others
	nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist
T37309	Diadenosine pentaphosphate pentaammonium
	Diadenosine pentaphosphate pentaammonium, an endogenous vasoactive purine dinucleotide isolated from thrombocytes, is one component of the diadenosine polyphosphates (ApnA, n=2-7) family. These compounds are found in secretory vesicles, including those in platelets, chromaffin cells, Torpedo synaptic terminals, and brain synaptosomes[1][2].
T40721	N7-Methyl-guanosine-5'-triphosphate-5'-adenosine N7-Methyl-guanosine-5'-triphosphate-5'-adenosine,m7GpppA
	N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog employed in the process of in vitro RNA transcription.
T73939	IACS-8803 diammonium
	IACS-8803 diammonium 是一种高效环状二核苷酸的STING 激动剂，具有强大的全身抗肿瘤作用。
T73938	IACS-8803 disodium
	IACS-8803 disodium 是一种高效环状二核苷酸的STING 激动剂，具有强大的全身抗肿瘤作用。
T15412	GPP78 CAY10618	Autophagy	Autophagy
	GPP78 is a potent inhibitor of Nampt (IC50: 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion). GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells (IC50: 3.8 nM by inducing autophagy). GPP78 has anti-cancer and anti-inflammatory effect
T74135	N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium
	N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium 是体外 RNA 转录中使用的二核苷酸帽类似物。
T74998	LmNADK1-IN-1
	LmNADK1-IN-1 (compound MC1) 是利斯特氏菌烟酰胺腺嘌呤二核苷酸激酶 (NADK1) 的抑制剂，Ki 值为 54 nM。LmNADK1-IN-1 可用于细菌感染的研究。
T74727	CL845-PAB-Ala-Val-C5-MC
	CL845-PAB-Ala-Val-C5-MC 是一种可结合的 STING 配体，由专有的环状二核苷酸 CL845 合成。CL845-PAB-Ala-Val-C5-MC 可用于生物偶联。
T75289	NAD sodium
	NAD sodium（β-Nicotinamide Adenine Dinucleotide sodium）为NAD的同类物，能在有机底物氧化反应中被还原为β-烟酰胺腺嘌呤二核苷酸（NADH）。此外，NAD sodium转化成的NADH能传递至线粒体内，间接促进ATP的生成。
T39829	BPK-25
	BPK-25 is an active acrylamide compound that enhances the degradation of proteins in the nucleosome remodeling and deacetylation (NuRD) complex through a post-translational mechanism involving covalent protein interaction. Additionally, BPK-25 acts as an inhibitor of TMEM173 activation by the cyclic dinucleotide ligand cGAMP.
T63649	Ned-K
	Ned-K 是一种烟酸腺嘌呤二核苷酸磷酸 (NAADP) 拮抗剂，对心肌缺血和再灌注 (sIR) 诱导的钙振荡表现出抑制作用。
T38091	3'3'-cGAMP (sodium salt)
	3'3'-cGAMP is a second messenger produced in bacteria by specific dinucleotide cyclases. It contains canonical 3'5'-phosphodiester bonds and regulates chemotaxis, colonization, and other cellular functions. 3'3'-cGAMP shows weaker binding to the adapter protein stimulator of interferon genes (STING; Kd = 1.04 μM) than 2'2'-cGAMP and 2'3'-cGAMP but has similar binding affinity to 3'2'-cGAMP (Kd = 1.61 μM) and cyclic di-GMP . 3'3'-cGAMP induces IFN-β mRNA expression in L929 cells (EC50 = 40.5 nM).
T41088	Diadenosine pentaphosphate pentalithium
	Diadenosine pentaphosphate pentalithium is an endogenous vasoactive purine dinucleotide, isolated from thrombocytes. It is a member of the diadenosine polyphosphates (ApnA, n=2–7) and is found in secretory vesicles of platelets, chromaffin cells, Torpedo synaptic terminals, and brain synaptosomes.
T36996	MSA-2 dimer
	MSA-2 dimer is a selective, orally active non-nucleotide STING agonist (Kd=145 μM) with long-term antitumor and immunogenic activity. MSA-2 dimer is bound to STING as a non-covalent dimer exhibiting higher permeability than cyclic dinucleotide[1]. MSA-2 dimer (60 mg/kg; p.o.; 50 days) inhibits tumor growth and prolongs overall survival[1]. MSA-2 dimer (40 mg/kg; s.c.; 25 days) induces complete tumor regression[1].MSA-2 dimer (60 mg/kg; p.o.; 4 hours) increases proinflammatory cytokine (IFN-β) le...
T76118	Malate dehydrogenase
	Malate dehydrogenase 催化草酰乙酸盐和苹果酸盐的相互转化，与二核苷酸辅酶的氧化/还原相关。
T76171	L-Amino acid oxidase
	L-Amino acid oxidase（L-氨基酸氧化酶）是一种含黄素腺嘌呤二核苷酸的同源二聚体，能够将L-氨基酸立体特异性地催化氧化脱氨，生成α-酮酸和氨。
T37310	Diadenosine pentaphosphate pentasodium
	Diadenosine pentaphosphate pentasodium, an endogenous vasoactive purine dinucleotide isolated from thrombocytes, serves as a key component of secretory vesicles in platelets, chromaffin cells, Torpedo synaptic terminals, and brain synaptosomes. This compound, along with other diadenosine polyphosphates (ApnA, n=2-7), plays a crucial role in physiological processes[1][2].
T78360	Glyceraldehyde phosphate dehydrogenase GAPDH,G3PDH,GADPH
	Glyceraldehyde phosphate dehydrogenase是一种酶，既是抗胸腺细胞剂也是抗凋亡剂的靶点，它负责催化过羟基自由基对还原型烟酰胺腺嘌呤二核苷酸（NADH）的链氧化反应。
T81648	NOX2-IN-1
	NOX2-IN-1 是 NOX2 (烟酰胺腺嘌呤二核苷酸磷酸氧化酶异构体 2) 的抑制剂。该化合物旨在针对 p47phox-p22phox 蛋白间相互作用，展现出优秀的结合亲和力及细胞活性。
T36985	Cyclic di-UMP (sodium salt)
	Cyclic di-UMP is a pyrimidine-containing cyclic dinucleotide (CDN).1It is produced by bacterial cGAS/DncV-like nucleotidyltransferases (CD-NTases), such as LpCdnE02 fromL. pneumophila, and binds to cGAS, in the apo or dsDNA-bound forms, with reduced affinity compared to 2'3'-cGAMP or 3'3'-cGAMP .1,2Cyclic di-UMP is intended for use as a negative control for cyclic di-GMP signaling. 1.Whiteley, A.T., Eaglesham, J.B., de Oliveira Mann, C.C., et al.Bacterial cGAS-like enzymes synthesize diverse nuc...
T36066	NADP+ (sodium salt hydrate)
	NADP+ is the oxidized form of the electron donor nicotinamide adenine dinucleotide phosphate . It serves as a cofactor in various biological reactions. In addition, the balance between these reduced and oxidized forms plays key roles in diverse cellular functions, including cell survival, the maintenance of redox status, and intracellular signaling. For example, binding of NADP+ to β-subunits of Kv channels activates ion transport, whereas NADPH stabilizes channel inactivation. NADP+ is biosynth...
T35654	2'2'-cGAMP (sodium salt)
	2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds. It binds to the adapter protein stimulator of interferon genes , which is a component of the innate immune response that activates the type I interferon pathway when bound to cyclic dinucleotides. 2'2-cGAMP shows weaker binding to STING than 2'3'-cGAMP but binds more strongly than 3'3'-cGAMP , cyclic di-GMP , or 3'2'-cGAMP, which bind in the micromolar range (Kds = 1.04, 1.21, or 1.61 μM, respecti...
T35922	NAADP (sodium salt)
	Nicotinic acid adenine dinucleotide phosphate (NAADP) is a secondary messenger that induces calcium mobilization. It induces calcium release from endosomes and lysosomes via two-pore channel 2 (TPC2) and TPC1, which then stimulates large-scale calcium release from granules and the endoplasmic reticulum mediated by type 1 ryanodine receptors (RyR2s), RyR3s, and inositol-(1,4,5)-triphosphate receptors (IP3Rs). NAADP induces calcium mobilization in sea urchin and starfish eggs post fertilization to...
T79313	BI 7446	STING	Immunology/Inflammation
	BI 7446 是一种基于环状二核苷酸 (CDN) 的高效、特异性STING (干扰素基因刺激蛋白) 激动剂。它能激活所有五种STING变体并在体外诱导肿瘤特异性的免疫介导反应，从而消除肿瘤。此化合物适用于免疫肿瘤学领域的研究。

化合物

Nicotinamide 1,N6-ethenoadenine dinucleotide

Cat.No: T78408

Synonym: ε-NAD

ε-NAADP+ sodium

Cat.No: T83801

Synonym: Etheno-NAADP,β-Nicotinic Acid-1,N6-Ethenoadenine dinucleotide phosphate,Nicotinic Acid adenine dinucleotide phosphate

Cat.No: T83675

Synonym: Thionicotinamide NAD,Thionicotinamide adenine dinucleotide

6-Biotin-17-NAD+ sodium

Cat.No: T83800

Synonym: 6-Biotin-17-Nicotinamide adenine dinucleotide,β-Nicotinamide-N6-(2-(6-(6-[biotinyl]aminohexanoyl)aminohexanoyl)aminoethyl)adenine dinucleotide

6-alkyne NAD+ sodium

Cat.No: T83799

Synonym: β-Nicotinamide-N6-propargyladenine dinucleotide,6-Parg NAD,6-alkyne Nicotinamide adenine dinucleotide,Click Tag™ 6-alkyne NAD

β-Nicotinamide adenine dinucleotide reduced dipotassium

Cat.No: T77253

Deaminocozymase

Cat.No: T31261

Synonym: Deamino-NAD,Deamino DPN,Nicotinamide-hypoxanthine dinucleotide,Deamino NAD,Desamino-DPN

Flavin Adenine Dinucleotide DiSodium Salt xhydrate

Cat.No: T64590

8-bromo NAD+ sodium

Cat.No: T83798

Synonym: 8-bromo Nicotinamide adenine dinucleotide,N(8-bromo-A)D+

8-(2-azidobenzylthio) NAD+ sodium

Cat.No: T83844

Synonym: 8-(2-azidobenzylthio) Nicotinamide adenine dinucleotide,Click Tag™ 8-(2-azidobenzylthio) NAD+

8-(4-azidophenacylthio) NAD+ sodium

Cat.No: T83845

Synonym: Click Tag™ 8-(4-azidophenacylthio) NAD+,8-(4-azidophenacylthio) Nicotinamide adenine dinucleotide

Cat.No: T9137

Synonym: [1,1'-Biphenyl]-4-carboxamide, N-[3-[[(4-fluorophenyl)sulfonyl]amino]-4-hydroxyphenyl]-,GUN35901

Target: STING

Keto-pantoyllactone

Cat.No: T20466

Synonym: 二氢-4,4-二甲基-2,3-呋喃二酮,Keto pantoyllactone,Ketopantoyllactone,Dihydro-4,4-dimethyl-2,3-furandione

Target: Others

Cat.No: T40686

Synonym: NSC 286193,Riboxamide,噻唑呋林

Target: Dehydrogenase

NAAD sodium salt

Cat.No: T33565

Synonym: NAAD钠盐,NAAD Na salt,Deamido Nad Sodium Salt,NAAD Na, NaAD

Cat.No: TP2083L

Synonym: Ac9-25 acetate(284040-76-2 free base)

Target: Others

NADPH tetrasodium salt

Cat.No: T7092

Target: Others, Ferroptosis, Endogenous Metabolite

Inarigivir ammonium

Cat.No: T9518

Synonym: ORI-9020 ammonium,SB-9200 ammonium,Inarigivir铵

Target: HBV

Cat.No: T1880

Target: Others

Cat.No: T12781

Target: Others

Cat.No: T11596

Target: Others

Cat.No: T7365

Synonym: ORI-9020,SB-9000

Target: HBV

Cat.No: T22670

Target: Others

Diadenosine pentaphosphate pentaammonium

Cat.No: T37309

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine

Cat.No: T40721

Synonym: N7-Methyl-guanosine-5'-triphosphate-5'-adenosine,m7GpppA

IACS-8803 diammonium

Cat.No: T73939

IACS-8803 disodium

Cat.No: T73938

Cat.No: T15412

Synonym: CAY10618

Target: Autophagy

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium

Cat.No: T74135

Cat.No: T74998

CL845-PAB-Ala-Val-C5-MC

Cat.No: T74727

Cat.No: T75289

Cat.No: T39829

Cat.No: T63649

3'3'-cGAMP (sodium salt)

Cat.No: T38091

Diadenosine pentaphosphate pentalithium

Cat.No: T41088

Cat.No: T36996

Malate dehydrogenase

Cat.No: T76118

L-Amino acid oxidase

Cat.No: T76171

Diadenosine pentaphosphate pentasodium

Cat.No: T37310

Glyceraldehyde phosphate dehydrogenase

Cat.No: T78360

Synonym: GAPDH,G3PDH,GADPH

Cat.No: T81648

Cyclic di-UMP (sodium salt)

Cat.No: T36985

NADP+ (sodium salt hydrate)

Cat.No: T36066

2'2'-cGAMP (sodium salt)

Cat.No: T35654

NAADP (sodium salt)

Cat.No: T35922

Cat.No: T79313

Target: STING

Cat. No.	Product Name	Target	Signaling Pathways
T5067	Flavin adenine dinucleotide disodium salt Flavin Adenine Dinucleotide Disodium,黄素腺嘌呤二核苷酸二钠,FAD sodium salt,FAD-Na2	Others; Endogenous Metabolite	Metabolism; Others
	Flavin adenine dinucleotide disodium salt (FAD sodium salt) 是一种辅酶，作用是促进细胞氧化还原反应中黄素酶的电子转移。
T65172	Flavin adenine dinucleotide FAD	Endogenous Metabolite	Metabolism
	Flavin adenine dinucleotide (FAD) 是一种氧化还原辅因子，是蛋白质的辅基，参与机体多种代谢反应。
T1609	NAD+ 烟酰胺腺嘌呤二核苷酸,Cozymase,煙酸胺,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD	NADPH; Endogenous Metabolite	Metabolism
	NAD+ (β-Nicotinamide Adenine Dinucleotide) 即烟酰胺腺嘌呤二核苷酸，是转递氢离子的辅酶。
T8150	Nudifloramide 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide,1-甲基-6-氧代吡啶-3-甲酰胺	PARP; Endogenous Metabolite	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) 是烟酰胺-腺嘌呤二核苷酸(NAD) 降解的一种最终产物，可显著抑制PARP-1活性。
T6220	Nicotinamide riboside chloride 烟酰胺核糖氯酸盐,烟酰胺核苷	Sirtuin; Endogenous Metabolite	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Nicotinamide riboside Chloride 是维生素 B3 的来源，可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。它是具有口服活性的 NAD+的前体，增加 NAD+水平并激活SIRT1和SIRT3，可用于研究阿尔茨海默氏病的认知退化。
T0617	Nicotinamide N-oxide Nicotinamide-N-oxide,Nicotinamide 1-oxide,N-氧代烟酰胺,烟酰胺-N-氧化物,1-oxynicotinamide	c-Myc; Endogenous Metabolite; CXCR; Drug Metabolite	Autophagy; Cell Cycle/Checkpoint; GPCR/G Protein; Immunology/Inflammation; Metabolism
	Nicotinamide N-oxide (Nicotinamide 1-oxide) 是生物体内烟酰胺分解代谢物，是高效选择性CXCR2受体拮抗剂。
T5283	NADH disodium salt Disodium NADH,NADH, disodium salt hydrate,beta-烟酰胺腺嘌呤二核苷二钠	Others; Endogenous Metabolite	Metabolism; Others
	NADH disodium salt (Disodium NADH) hydrate 是氧化还原酶的辅酶。NADH disodium salt hydrate 在分解代谢过程中起到再生电子供体的作用，包括糖酵解，柠檬酸循环和β-氧化。
T0879	Niacin Vitamin B3,烟酸(维生素B3),Nicotinic acid	Endogenous Metabolite; Autophagy	Autophagy; Metabolism
	Niacin (Nicotinic acid)，也称为烟酸和维生素 B3，是一种水溶性必需的 B 族维生素，用于治疗维生素缺乏症以及高脂血症，血脂异常，高甘油三酯血症，并降低心肌梗塞的风险
T22446	NADP disodium salt Disodium NADP,Triphosphopyridine nucleotide disodium salt,beta-烟酰胺腺嘌呤二核苷酸磷酸二钠盐	Others	Others
	NADP disodium salt (Disodium NADP) 是一种氧化还原辅助因子，是一种烟酰胺腺嘌呤二核苷酸。它是代谢中电子转移的关键辅因子，可以被交替氧化 (NADP+) 和还原 (NADPH)。
T1331	Riboflavin phosphate sodium Riboflavin 5'-phosphate sodium,核黄素磷酸钠(维生素B2),Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,核黄素磷酸钠,FMN-Na,riboflavin-5'-phosphate	Endogenous Metabolite	Metabolism
	Riboflavin phosphate sodium (FMN) 是 riboflavin 的磷酸钠盐形式，riboflavin 是一种水溶性和必需的微量营养素，是自然产生的维生素B复合物的主要生长促进因子。Riboflavin phosphate sodium 转化为2种辅酶，黄素单核苷酸(FMN)和黄素腺嘌呤二核苷酸(FAD)，这两种辅酶通过帮助脂肪、碳水化合物和蛋白质的代谢来产生能量，并且是红细胞形成和呼吸、抗体产生以及调节人体生长和繁殖所必需的。
T4721	β-Nicotinamide mononucleotide β-NM,β烟酰胺单核苷酸,烟酰胺单核苷酸	Others; Endogenous Metabolite	Metabolism; Others
	β-Nicotinamide mononucleotide (β-NM) 是烟酰胺磷酸核糖转移酶 (NAMPT) 反应的产物。β-nicotinamide mononucleotide 的作用包括其在细胞生化功能、心脏保护、糖尿病、肥胖相关并发症和阿尔茨海默病中的作用。
TN2725	2',5,6',7-Tetrahydroxyflavanone	Others	Others
	(2S)-2',5,6',7-Tetrahydroxyflavanone can inhibit the lipid peroxide formation induced by adenosine diphosphate and reduced nicotinamide adenine dinucleotide phosphate in rat liver homogenate.
T0937	Riboflavin Vitamin B2,维生素B2,E101	Endogenous Metabolite	Metabolism
	Riboflavin (E101)，一种人内源性代谢物，是极易吸收的微量营养素。
T13606L	cGAMP disodium
	cGAMP disodium 是在细菌中发现的一种环二核苷酸 (CDN) ，可作为内源性第二信使，影响干扰素的产生以响应胞浆 DNA。cGAMP disodium 通过激活干扰素基因刺激因子 (STING)使 I 型干扰素和其他免疫介质的信号产生级联现象。cGAMP disodium 是一种有效的舌下免疫佐剂，能使免疫功能（血清抗 PA 中和和气道分泌物抗 PA SIgA 反应）更好的发挥作用。
T4448	NADP
	NADP，也称为烟酰胺腺嘌呤二核苷酸磷酸，是各种代谢过程中电子转移所必需的重要氧化还原辅因子。它在促进细胞能量产生和维持细胞内氧化还原平衡方面发挥着关键作用。

天然产物

Flavin adenine dinucleotide disodium salt

Cat.No: T5067

Synonym: Flavin Adenine Dinucleotide Disodium,黄素腺嘌呤二核苷酸二钠,FAD sodium salt,FAD-Na2

Target: Others, Endogenous Metabolite

Flavin adenine dinucleotide

Cat.No: T65172

Synonym: FAD

Target: Endogenous Metabolite

Cat.No: T1609

Synonym: 烟酰胺腺嘌呤二核苷酸,Cozymase,煙酸胺,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD

Target: NADPH, Endogenous Metabolite

Cat.No: T8150

Synonym: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide,1-甲基-6-氧代吡啶-3-甲酰胺

Target: PARP, Endogenous Metabolite

Nicotinamide riboside chloride

Cat.No: T6220

Synonym: 烟酰胺核糖氯酸盐,烟酰胺核苷

Target: Sirtuin, Endogenous Metabolite

Nicotinamide N-oxide

Cat.No: T0617

Synonym: Nicotinamide-N-oxide,Nicotinamide 1-oxide,N-氧代烟酰胺,烟酰胺-N-氧化物,1-oxynicotinamide

Target: c-Myc, Endogenous Metabolite, CXCR, Drug Metabolite

NADH disodium salt

Cat.No: T5283

Synonym: Disodium NADH,NADH, disodium salt hydrate,beta-烟酰胺腺嘌呤二核苷二钠

Target: Others, Endogenous Metabolite

Cat.No: T0879

Synonym: Vitamin B3,烟酸(维生素B3),Nicotinic acid

Target: Endogenous Metabolite, Autophagy

NADP disodium salt

Cat.No: T22446

Synonym: Disodium NADP,Triphosphopyridine nucleotide disodium salt,beta-烟酰胺腺嘌呤二核苷酸磷酸二钠盐

Target: Others

Riboflavin phosphate sodium

Cat.No: T1331

Synonym: Riboflavin 5'-phosphate sodium,核黄素磷酸钠(维生素B2),Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,核黄素磷酸钠,FMN-Na,riboflavin-5'-phosphate

Target: Endogenous Metabolite

β-Nicotinamide mononucleotide

Cat.No: T4721

Synonym: β-NM,β烟酰胺单核苷酸,烟酰胺单核苷酸

Target: Others, Endogenous Metabolite

2',5,6',7-Tetrahydroxyflavanone

Cat.No: TN2725

Target: Others

Cat.No: T0937

Synonym: Vitamin B2,维生素B2,E101

Target: Endogenous Metabolite

Cat.No: T13606L

Cat.No: T4448

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