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Search Results for " anti-anxiety "

13

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T9272	Xaliproden hydrochloride	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Xaliproden hydrochloride 是选择性和具有口服活性的5-HT1A 受体激动剂，对大鼠海马中的 5-HT1A 特异性结合位点表现出高亲和力。它也是选择性的多巴胺D2受体拮抗剂，具有抗抑郁和抗焦虑作用，有用于神经退行性疾病的研究潜力。
T7644	DPN Diarylpropionitrile,2,3-双(4-羟苯基)丙腈	Apoptosis; Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Autophagy	Apoptosis; Autophagy; Endocrinology/Hormones
	DPN (Diarylpropionitrile) 是一种非甾体雌激素受体 ERβ选择性配体，其 EC50值为 0.85 nM。DPN 在许多神经系统疾病具有神经保护作用。
T1696	2-(1-Piperazinyl)pyrimidine	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	2-(1-Piperazinyl)pyrimidine 用作抗焦虑药。
T35707	3'-Sialyllactose sodium 3'-SL sodium	NF-κB	NF-κB
	3'-Sialyllactose sodium 是一种益生元，具有抗炎活性，可维持免疫稳态。3'-Sialyllactose sodium 可减少压力源引起的焦虑样行为，可用于研究炎症和关节炎。
T1279	Vilazodone 维拉佐酮,SB659746A,EMD 68843	5-HT Receptor; Serotonin Transporter	GPCR/G Protein; Neuroscience
	Vilazodone (SB659746A) 是一种可口服的选择性 5 -羟色胺再摄取抑制剂 (SSRI) 和部分5-HT1A 受体激动剂。它有抗抑郁作用，可用于抑郁症和情绪性疾病的研究。
T16418	Oxyfenamate P 301,Oxyphenamate,奥芬达唑	Others	Others
	Oxyfenamate has anti-anxiety actions. It is also used in anxiety neuroses.
T10869L	CP-409092	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.
T10869	CP-409092 hydrochloride	Others	Others
	CP-409092 hydrochloride is a partial agonist of the GABAA receptor with anti-anxiety activity.
T30321	Bentazepam Tiadipone,CI-718,Knoll brand of bentazepam,Thiadipone
	Bentazepam is a thienodiazepine, which is a benzodiazepine analogue. It has anti-anxiety, anti-convulsion, sedative and skeletal muscle relaxation properties.
T31039	CP-122721 UNII-R7OYP6N58F,CP122721
	CP-122721 is an NK1 receptor antagonist with a unique antidepressant, anti-anxiety, and antiemetic properties. It is also an effective selective substance P receptor antagonist.
T26772	Tacitin Tacitin,Benzoctamine HCl,Methyl(methyl-9,10-ethano-9(10H)-anthryl)ammonium chloride,Tacitine,Benzoctamine Hydrochloride,Benzoctamine (hydrochloride)	Others	Others
	Tacitin (Benzoctamine Hydrochloride) 显示出镇静和抗焦虑的特性。Tacitin 能阻断中枢突触后5-羟色胺受体。
T61476	Thioridazine
	Thioridazine is a chemical compound characterized by its potent anti-psychotic and anti-anxiety activities. As an antagonist of the dopamine receptor D2 family proteins, it exhibits a strong inhibitory effect on the PI3K-Akt-mTOR signaling pathways, resulting in anti-angiogenic effects. It also demonstrates significant antiproliferative and apoptosis induction effects in a diverse range of cancer cells, specifically targeting cancer stem cells (CSCs) [1] [2] [3] [4].
T73608	Muscimol hydrochloride
	Muscimol (Agarin; Agarine) hydrochloride 是一种具有精神活性的异恶唑。Muscimol hydrochloride 也是抑制性神经递质 GABA 离子型受体的选择性激动剂。Muscimol hydrochloride 可以从毒蝇伞和相关蘑菇中分离出来。总之，Muscimol 是一种有效的 GABAA 受体激动剂 (EC50=0.2 μM)，部分 GABAC 受体激动剂和无活性的 GABAB 受体激动剂。Muscimol hydrochloride 具有镇静、抗焦虑和致幻作用。

化合物

Xaliproden hydrochloride

Cat.No: T9272

Target: Dopamine Receptor, 5-HT Receptor

Cat.No: T7644

Synonym: Diarylpropionitrile,2,3-双(4-羟苯基)丙腈

Target: Apoptosis, Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Autophagy

2-(1-Piperazinyl)pyrimidine

Cat.No: T1696

Target: Adrenergic Receptor

3'-Sialyllactose sodium

Cat.No: T35707

Synonym: 3'-SL sodium

Target: NF-κB

Cat.No: T1279

Synonym: 维拉佐酮,SB659746A,EMD 68843

Target: 5-HT Receptor, Serotonin Transporter

Cat.No: T16418

Synonym: P 301,Oxyphenamate,奥芬达唑

Target: Others

Cat.No: T10869L

Target: GABA Receptor

CP-409092 hydrochloride

Cat.No: T10869

Target: Others

Cat.No: T30321

Synonym: Tiadipone,CI-718,Knoll brand of bentazepam,Thiadipone

Cat.No: T31039

Synonym: UNII-R7OYP6N58F,CP122721

Cat.No: T26772

Synonym: Tacitin,Benzoctamine HCl,Methyl(methyl-9,10-ethano-9(10H)-anthryl)ammonium chloride,Tacitine,Benzoctamine Hydrochloride,Benzoctamine (hydrochloride)

Target: Others

Cat.No: T61476

Muscimol hydrochloride

Cat.No: T73608

Cat. No.	Product Name	Target	Signaling Pathways
T4814	(R)-5-Oxopyrrolidine-2-carboxylic acid D-Pyroglutamic acid,(R)-(+)-2-Pyrrolidone-5-carboxylic acid,D-焦谷氨酸	Others; Endogenous Metabolite	Metabolism; Others
	(R)-5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) 是内源性代谢产物的一种。
T68953	Arecoline	Reactive Oxygen Species; AChR	Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	Arecoline 是一种来自棕榈科植物槟榔的天然生物碱，是有效的烟碱和毒蕈碱乙酰胆碱受体的部分激动剂。Arecoline 具有抗焦虑和抗寄生虫活性，可诱导氧化应激，可用于研究阿尔茨海默病和老年性痴呆。
TCS2170	2,5-Dihydroxyacetophenone Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,2 '，5'-二羟基苯乙酮,Acetylhydroquinone,2,5-二羟基苯乙酮,DHAP	ERK; NF-κB; Tyrosinase	MAPK; NF-κB; Proteases/Proteasome
	2,5-Dihydroxyacetophenone (Quinacetophenone) 是从熟地黄中分离出的一种天然产物，通过阻断 ERK1/2和 NF-κB 信号通路，抑制活化巨噬细胞中炎症介质的产生。

天然产物

(R)-5-Oxopyrrolidine-2-carboxylic acid

Cat.No: T4814

Synonym: D-Pyroglutamic acid,(R)-(+)-2-Pyrrolidone-5-carboxylic acid,D-焦谷氨酸

Target: Others, Endogenous Metabolite

Cat.No: T68953

Target: Reactive Oxygen Species, AChR

2,5-Dihydroxyacetophenone

Cat.No: TCS2170

Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,2 '，5'-二羟基苯乙酮,Acetylhydroquinone,2,5-二羟基苯乙酮,DHAP

Target: ERK, NF-κB, Tyrosinase

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