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Cat. No. | Product Name | ||
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LF1000 | 多样性核心预制库 | 50000 compounds | |
For your convenience, there are Diversity Sets of 5,000, 10,000, 15,000, and 20,000 compounds with no structure overlap. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T68065 |
Enloplatin
|
||
Enloplatin 是一种卡铂类似物,在治疗晚期卵巢癌有部分作用。 | |||
T77688 |
Dipotassium tetrachloroplatinate
Potassium tetrachloroplatinate |
Others | Others |
Dipotassium tetrachloroplatinate (Potassium tetrachloroplatinate) 在实体肿瘤系中表现出抗肿瘤活性,可用于有治疗肿瘤疾病。Dipotassium tetrachloroplatinate 还可充当放射增敏剂,可增强热疗杀伤作用。 | |||
T2410 |
Nedaplatin
奈达铂,NSC 375101D |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Nedaplatin (NSC-375101D) 是顺铂的衍生物,是肿瘤集落形成单位的 DNA 损伤剂,IC50为94 μM。 | |||
T1058 |
Carboplatin
NSC 241240,卡铂,CBDCA,JM-8 |
DNA Alkylator/Crosslinker; DNA/RNA Synthesis; Autophagy | Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Carboplatin (JM-8) 是一种顺铂衍生物,一种 DNA 合成抑制剂。Carboplatin 能够与 DNA 结合,抑制复制和转录并诱导细胞死亡。Carboplatin 具有抗肿瘤活性。 | |||
T38738 |
Imifoplatin
Imifoplatin,PT-112 |
||
Imifoplatin is a platinum-based agent belonging to the phosphaplatin family. Imifoplatin exhibits antineoplastic activity. | |||
T7221 |
Satraplatin
BMS182751,JM216,顺式-二氯-反式-二乙酸-氨-环己胺合铂,BMY45594 |
DNA Alkylator/Crosslinker; DNA Alkylation | DNA Damage/DNA Repair |
Satraplatin (BMS182751) 是一种烷化剂 ,是一种口服的抗肿瘤铂 (IV) 复合物,具有广泛的抗肿瘤效果。 | |||
T4368 |
Miriplatin
米铂,SM-11355 |
DNA Alkylator/Crosslinker | DNA Damage/DNA Repair |
Miriplatin (SM-11355) 是一种烷化剂,是一种用于 TACE 的铂络合物,有望用于治疗肝细胞癌。 | |||
T0117 |
Suplatast (Tosilate)
IPD 1151T,甲磺司特,Suplatast tosilate,Suplatast Tosylate |
IL Receptor; Interleukin | Immunology/Inflammation |
Suplatast Tosilate (IPD 1151T) 是一种口服有活性的 Th2 细胞因子抑制剂,能够阻碍 Th2 细胞产生 IL-4 和 IL-5 ,并对 IgE 的合成具有抑制作用。它是一种抗过敏剂,它具有抗纤维化、抗哮喘及抗炎特性。 | |||
T15771 |
Lobaplatin
D-19466,络铂 |
DNA Alkylation | DNA Damage/DNA Repair |
Lobaplatin (D-19466) 是一种铂 (II) 复合物的非对映混合物,是一种有前途的抗肿瘤化疗药物,在多种肿瘤类型的患者中具有活性。 | |||
T35300 |
Zeniplatin
Zeniplatinum |
Others | Others |
Zeniplatin (Zeniplatinum) 是一种新顺铂复合物,具有抗癌活性,可用于治疗转移性黑色素瘤和肾癌。 | |||
T21297 |
Miriplatin hydrate
SM-11355 (hydrate),Miripla,Miriplatin,SM 11355,SM11355,SM-11355,Miriplatin hydrate |
DNA Alkylation | DNA Damage/DNA Repair |
Miriplatin hydrate (SM-11355 (hydrate)) (MPT)是一种用于TACE 的新型铂类化合物,在肝细胞癌(HCC)的治疗中显示出良好的前景。米铂是一种亲脂性铂复合物,容易悬浮在碘油中,并在肿瘤组织中逐渐释放活性铂化合物。 | |||
T27271 |
Enzaplatovir
BTA-585,BTA 585,BTAC585,BTA585,BTA-C585 |
||
Enzaplatovir is an inhibitor of Respiratory Syncytial Virus (RSV), can be used as a viral fusion protein inhibitor. | |||
T1564 |
Cisplatin
cis-Diaminodichloroplatinum,CDDP,顺铂 |
DNA Alkylator/Crosslinker; Ferroptosis; DNA/RNA Synthesis; Autophagy | Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Cisplatin (CDDP) 是一种 DNA 交联剂。Cisplatin 具有抗肿瘤活性,能够通过在癌细胞中形成 DNA 加合物来抑制 DNA 合成。Cisplatin 还可激活铁死亡并诱导自噬。 | |||
T68144 |
Spiroplatin
|
Others | Others |
Spiroplatin(TNO-6)是一种新型含铂类似物,具有抗肿瘤活性,常用用于研究实体肿瘤。 | |||
T0164 |
Oxaliplatin
L-OHP,奥沙利铂 |
DNA Alkylator/Crosslinker; DNA/RNA Synthesis; Autophagy | Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Oxaliplatin (L-OHP) 是一种 DNA 烷化剂,一种 DNA 合成抑制剂。Oxaliplatin 会导致 DNA 交联损伤,阻止 DNA 复制和转录并导致细胞死亡。Oxaliplatin 可以诱导细胞自噬。 | |||
T34085 | Platenolide I | ||
Platenolide I is a macrolactone extracted from Streptomyces platensis. | |||
T28398 |
Phenanthriplatin
cis-[Pt(NH3)2-(phenanthridine)Cl]NO3 |
||
Phenanthriplatin, also known as cis-[Pt(NH3)2-(phenanthridine)Cl]NO3, is a new drug candidate. It belongs to a family of platinum(II)-based agents which includes cisplatin, oxaliplatin and carboplatin. Phenanthriplatin Acts As a Covalent Poison of Topoiso | |||
T68105 | monohydroxycisplatin | ||
monohydroxycisplatin 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T68105,CAS号为 101311-26-6。 | |||
T124100 |
Platycoside G3
|
||
Platycoside G3 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124100,CAS号为 849758-44-7。 | |||
T63335 |
Antiplatelet agent 2
|
||
Antiplatelet agent 2 是一种替卡格雷 (Ticagrelor) 类似物,表现出抗血小板作用,能够用于血小板凝集的研究。 | |||
T21307 |
Heptaplatin
NSC644591 NSCD644591 SKI2053R,Heptaplatin Sunpla,HTP |
||
Heptaplatin, a new platinum derivative with anticancer activity, is used against various cancer cell lines, including cisplatin-resistant cancer cell lines. It has been reported to have a response rate of 17% as a single agent, and tolerable toxicity in t | |||
TP2240 |
Deapio platycodin D
|
Others | Others |
Deapio platycodin D is extracted from Platycodon grandiforus. | |||
T21323 |
Picoplatin
NX 473,AMD-473,AMD473,NX-473,NX473,AMD 473 |
||
Picoplatin has a broad spectrum of antineoplastic activity and is designed to overcome platinum drug resistance. Picoplatin alkylates DNA, forming both intra- and inter-strand cross-linkages, resulting in the inhibition of DNA replication and transcriptio | |||
T131503 |
Betulinic acid (Mairin; Gratiolone; Platanol)
|
||
Betulinic acid (Mairin; Gratiolone; Platanol) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131503。 | |||
T32189 |
Iproplatin
JM-9,CHIP,Code name: JM9,JM 9 |
||
Iproplatin is a synthetic second-generation platinum-containing compound related to cisplatin. Iproplatin binds to and forms DNA crosslinks and platinum-DNA adducts, resulting in DNA replication failure and cell death. Although less prone to glutathione i | |||
T34086 |
Platonin
NK 19 |
||
Platonin is a therapeutic immunomodulating medicine and a possible medicine against ischemic stroke. | |||
TP2198 |
Platelet Membrane Glycoprotein IIB Peptide (296-306)
|
Others | Others |
GPllb is composed of a 125 Kd heavy chain that is disulfide-linked to a 23 Kd light chain. Hydropathicity analysis of the cDNA sequence indicates that GPllb is anchored to the platelet through a single transmembrane domain located within 20 amino acids of | |||
TP2466 |
Platelet factor 4 (59-70)
PF4 (59-70) |
||
Platelet factor 4 (59-70) elicits human neutrophil & monocyte chemotaxis. | |||
T63334 |
Antiplatelet agent 1
|
||
Antiplatelet agent 1 是一种替卡格雷 (Ticagrelor) 类似物,表现出抗血小板作用,能够用于血小板凝集的研究。 | |||
T61870 |
(rel)-Oxaliplatin
|
||
(rel)-Oxaliplatin is a DNA synthesis inhibitor that induces DNA crosslinking damage, inhibits DNA replication and transcription, and stimulates apoptosis. This compound has applications in cancer research [1] [2] [3]. | |||
T68140 |
sebriplatin
|
||
sebriplatin 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T68140,CAS号为 110172-45-7。 | |||
T82715 | Cisplatin-resistant cells-IN-1 | ||
Cisplatin-resistant cells-IN-1(化合物8)对顽固的铂类药物抗性细胞具有较高的细胞毒性。在低纳摩尔浓度范围内(IC50:0.14–1.79 μM in A549/A549-R, K562/K562-R, and MCF-7/MCF-7TamR cells),该化合物能有效降低代谢活性。 | |||
T71401 | Oxaliplatin-d10 | ||
Oxaliplatin-d10 is intended for use as an internal standard for the quantification of oxaliplatin by GC- or LC-MS. Oxaliplatin is a platinum-containing DNA-crosslinking agent. It induces the formation of DNA inter- and intrastrand crosslinks and DNA-protein adducts, inhibits DNA and RNA synthesis, and induces apoptosis in cancer cells. Oxaliplatin is cytotoxic to cisplatin-sensitive A2780(1A9) and KB-3-1 cells and cisplatin-resistant A2780-E(80) and KB-CP20 cells (IC50s = 0.12, 0.39, 4.7, and 2.... | |||
T71385 | Aroplatin | ||
Aroplatin is a synthetic liposomal formulation of bis-neodecanoate diaminocyclohexane platinum (NDDP), a third-generation platinum complex analogue of cisplatin, with potential antineoplastic activity. After displacement of the 2 long-chain aliphatic leaving groups (neodecanoic acid), platinum diaminocyclohexane (DACH) complexes become highly reactive and alkylate macromolecules, forming both inter- and intra-strand DNA crosslinks and inhibiting DNA synthesis, which results in tumor cell cytotox... | |||
TP1667 |
Platelet Factor 4 (58-70), human
|
||
Platelet Factor 4 (58-70), human is a polypeptide based on the 58-70 amino acid sequence of Platelet Factor 4 (pf-4) residues. | |||
T35634 |
Platensimycin
|
||
Platensimycin (PTM) is an antibiotic produced by S. platensis that inhibits Gram-positve bacteria by selectively inhibiting cellular lipid biosynthesis (IC50 = 0.1 μM). It targets the β-ketoacyl-acyl-carrier-protein synthase I/II, FabF/B, an enzyme that participates in the biosynthesis of fatty acids (IC50s = 48 and 160 nM for S. aureus and E. coli enzymes, respectively). By specifically targeting fatty acid synthesis in bacteria, PTM is thought to be a promising agent for overcoming antibiotic ... | |||
T68971 |
Ormaplatin
|
||
Ormaplatin is a platinum(IV) analogue with antineoplastic activity. Ormaplatin alkylates DNA, forming both inter- and intra-strand platinum-DNA crosslinks, which result in inhibition of DNA replication and transcription and cell-cycle nonspecific cytotoxicity. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) | |||
T12316 |
Oral antiplatelet agent 1
|
Others | Others |
Oral antiplatelet agent 1 is a potent antiplatelet agent with an IC50 of 2.94 μM in vitro. | |||
T123949 |
Platyphylloside
|
||
Platyphylloside 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T123949,CAS号为 90803-80-8。 | |||
T37883 |
(S)-Enzaplatovir
|
||
(S)-Enzaplatovir ((S)-BTA-C585) is the S-enantiomer of Enzaplatovir. (S)-Enzaplatovir shows antiviral activities with an EC50 of 56 nM for respiratory syncytial viral (RSV)[1]. | |||
T38125 |
Platencin
|
||
Platencin is a natural, broad spectrum Gram-positive antibiotic isolated from S. platensis, which is also the source of platensimycin . Platencin inhibits two key enzymes in bacterial fatty acid synthesis, β-ketoacyl-ACP synthases II and III (FabF and FabH, respectively), unlike platensimycin which only targets FabF. The IC50 values for platencin against FabF and FabH are 1.95 and 3.91 μg/ml, respectively. It does not exhibit cross-resistance to antibiotic resistant bacterial strains, including ... | |||
T69766 | Gusacitinib HCl | ||
Gusacitinib, also known as ASN-002 and EN-3351, is a potent dual inhibitor of SYK/JAK kinases. ASN002 showed strong antitumor activity in both hematological and solid tumor xenograft models. ASN002 strongly suppressed the SYK and JAK family kinase signaling pathways as measured in pLAT and pSTAT assays, respectively. When profiled in a panel of 178 cell lines, ASN002 showed strong anti-proliferative activity in many lymphoid/leukemia cell lines, including SU-DHL-6, SU-DHL-4, OCI-LY10, H929 and... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1260 |
3-O-beta-D-Glucopyranosylplatycodigenin
|
Others | Others |
3-O-Beta-D-Glucopyranosylplatycodigenin 是分离自桔梗根的一种齐墩果烷型三萜类化合物。它具有抗 HSC-T6 细胞增殖活性,IC50为 13.36 μM。 | |||
TMA0835 |
Deapi-platycodin D3
去芹糖桔梗皂苷D3,去芹-桔梗皂苷D3 |
Others | Others |
Deapi-platycodin D3 是一种三萜皂苷,从桔梗根中提取得到。 | |||
T3821 |
Deapioplatycodin D
Deapi-platycodin D,去芹糖桔梗皂苷 D,去芹糖桔梗皂苷D,DesapioplatycodinD |
Others; HCV Protease | Microbiology/Virology; Others; Proteases/Proteasome |
Deapioplatycodin D 是从桔梗中分离出的一种三萜皂苷,具有抗丙型肝炎病毒活性。 | |||
TN1555 |
Platycoside G1
桔梗皂苷G1,Deapi-platycoside E |
Others | Others |
Platycoside G1 (Deapi-platycoside E) 是一种从桔梗中发现的天然三萜皂苷。它具有较强的抗氧化作用。 | |||
TMS0943 |
Platicodigenin
桔梗皂苷元,Platycodigenin |
Others | Others |
Platicodigenin (Platycodigenin) 是从桔梗中分离出的桔梗素,在体外对 HSC-T6 细胞系具有抗增殖活性。 | |||
TN2088 |
Platycodin D2
桔梗皂苷D2 |
IL Receptor; HBV | Immunology/Inflammation; Microbiology/Virology |
Platycodin D2 是分离自桔梗的皂苷类物质,显示除抗癌活性。 | |||
T3889 |
Platycodin D
|
Prostaglandin Receptor; AMPK | Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; PI3K/Akt/mTOR signaling |
Platycodin D 是从桔梗中分离得到的一种皂苷类天然产物,是AMPKα的激活剂,具有抗肥胖活性。它可刺激 TNF-α 合成或抑制 TNF-α mRNA 的降解。 | |||
TN2089 |
Platycodin D3
桔梗皂苷D3,桔梗皂苷 D3 |
HCV Protease; NF-κB | Microbiology/Virology; NF-κB; Proteases/Proteasome |
Platycodin D3 是桔梗中有抗HCV 活性的一种三萜皂苷类天然产物。 | |||
T12500 |
Platycoside E
Platycodin E,桔梗苷E |
Others | Others |
Platycoside E (Platycodin E) 是一种桔梗皂苷元型皂苷,从桔梗的根中分离获得,能够促进 ovalbumin 免疫小鼠中血清 OVA 特异性IgG2a 和IgG2b 抗体的产生。它具有溶血活性和佐剂潜力。 | |||
TN2966 |
3''-O-acetyl-platyconic acid A
|
Others | Others |
3''-O-acetyl-platyconic acid A是一种天然产物,属于桔梗科桔梗属,其产品编号为 TN2966,CAS号为 1256935-28-0。3''-O-acetyl-platyconic acid A可用作对照参考。 | |||
TN4804 |
Platycoside A
|
Antifection | Microbiology/Virology |
Platycoside A has hemolytic activity and adjuvant potential on the immune responses to Newcastle disease virus-based recombinant avian influenza vaccine. It induces the IgG and IgG1 antibody responses in the immunized mice. | |||
TN4805 |
Platycoside K
|
Others | Others |
Platycoside K 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4805,CAS号为 899447-64-4。 | |||
TN4809 | Platyphylline | Others | Others |
Platyphylline 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4809,CAS号为 480-78-4。 | |||
TN6176 |
Platachromone B
5,7,4'-Trihydroxy-8-isoprenyl-2-styrylchromone |
||
Platachromone B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6176,CAS号为 1606149-63-6。 | |||
TN5759 |
Platachromone A
5,7,4'-Trihydroxy-6-isoprenyl-2-styrylchromone |
||
Platachromone A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5759,CAS号为 1606149-62-5。 | |||
TN2780 |
2''-O-acetyl-platyconic acid A
|
Others | Others |
2''-O-acetyl-platyconic acid A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2780,CAS号为 1256935-30-4。 | |||
TN6373 |
(5R)-Platyphyllone
|
||
(5R)-Platyphyllone 在生命科学相关研究中具有广泛的应用。 | |||
TN4806 | Platycoside M1 | Others | Others |
Platycoside M1 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4806,CAS号为 917482-67-8。 | |||
TN4802 |
Plathymenin
|
Others | Others |
Plathymenin 是一种从 Spatholobus suberectus 中分离出来的天然产物。 | |||
T40787 |
Platyconic acid A
|
||
Platyconic Acid A, derived from changkil saponins extracted from platycodon grandiflorum, is a potent compound employed for studying the mitigation of airway inflammation. | |||
TN5703 |
Platyphyllonol 5-O-β-D-xylopyranoside
Platyphyllonol 5-xylpyranoside |
||
Platyphyllonol 5-O-β-D-xylopyranoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5703,CAS号为 288141-04-8。 | |||
TN4803 |
Platycodin A
|
Others | Others |
Platycodin A是一种天然产物,属于桔梗科桔梗属,其产品编号为 TN4803,CAS号为 66779-34-8。Platycodin A可用作对照参考。 | |||
TN2770 |
2-Hydroxyplatyphyllide
|
Others | Others |
2-Hydroxyplatyphyllide is a natural product from Ligularia songarica. | |||
TN4807 | Platycoside M3 | Others | Others |
Platycoside M3 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4807,CAS号为 917482-69-0。 | |||
TN5516 |
Platanoside
|
||
Platanoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5516,CAS号为 133740-25-7。 | |||
TN4808 |
Platyphyllenone
|
Antifection | Microbiology/Virology |
Platyphyllenone 存在于 Alnus nepalensis 中并显示出抗丝虫活性。 | |||
TN6441 | Platycogenin A | ||
Platycogenin A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6441,CAS号为 1459719-53-9。 | |||
TN4810 |
Platyphyllonol
|
Influenza Virus | Microbiology/Virology |
Platyphyllonol 来自赤杨树皮,对 KBNP-0028 (H9N2) 禽流感病毒表现出中等活性。 | |||
TN5512 |
E,Z-Platanoside
|
||
E,Z-Platanoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5512,CAS号为 1197343-17-1。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00810 |
tPA Protein, Mouse, Recombinant (His)
PLAT,Reteplase,t-PA,tPA,Alteplase |
Mouse | HEK293 Cells |
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predominant route for enhancing cell survival is via an mTORdependent mechanism. | |||
TMPY-05019 |
Pla a 2 Protein, Platanus acerifolia, Recombinant (His)
|
Platanus acerifolia | HEK293 Cells |
PLA A2 Protein, Platanus acerifolia, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.7 kDa and the accession number is Q6H9K0.1. | |||
TMPJ-00332 |
tPA Protein, Human, Recombinant (His)
TPA,T-PA,t-plasminogen activator,Tissue plasminogen activato... |
Human | HEK293 Cells |
Tissue-type plasminogen activator (PLAT) is a protein that secreted into extracellular space. PLAT contains five domains: EGF-like domain, fibronectin type-I domain, 2 kringle domains and peptidase S1 domain. It belongs to the peptidase S1 family. The main function of this protein is to convert plasminogen into biologically active plasmin. As a protease, PLAT plays a crucial role in regulating blood fibrinolysis, maintaining the homeostasis of extracellular matrix and in modulating the post-tra... | |||
TMPH-02834 |
PAI-1 Protein, Mouse, Recombinant (His & SUMO)
|
Mouse | E. coli |
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of ... | |||
TMPJ-00625 |
Serpin E1 Protein, Mouse, Recombinant (His)
Pai1,Planh1,Plasminogen activator inhibitor 1,Serpin E1,Mr1,... |
Mouse | HEK293 Cells |
Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis. |