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Search Results for " ilex "

6

抑制剂 & 化合物

21

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T2400	Candesartan Cilexetil TCV-116,坎地沙坦酯,坎地沙坦西酯	Apoptosis; RAAS	Apoptosis; Endocrinology/Hormones
	Candesartan Cilexetil (TCV-116) 是一种血管紧张素II 拮抗剂，可用于治疗高血压。
T21591	1H-1-ethyl Candesartan Cilexetil	Others	Others
	1H-1-ethyl Candesartan Cilexetil 是 Candesartan cilexetil 批量合成中的一种工艺相关杂质，坎地沙坦酯是一种强效、长效和选择性血管紧张素 II 1 型受体 (AT1) 拮抗剂。
T25174	Brassilexin Brassilexine
	Brassilexin is a cyclobrassinin hydrolase inhibitor, a unique enzyme from the fungal pathogen Alternaria brassicicola.
T124123	Ilexside I
	Ilexside I 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124123。
T35705	20-hydroxy Arachidic Acid
	20-hydroxy Arachidic acid is a hydroxylated fatty acid that has been found in the suberin component of silver birch (B. pendula) outer bark as well as the leaves, roots, and wood of Q. ilex from Cala Violina and Colognole, Italy. 20-hydroxy Arachidic acid was identified as a potential inhibitor of human rhinovirus coat protein in a structure-based virtual screen.
T36174	Methyl 3,4-Dihydroxyphenylacetate
	Methyl 3,4-dihydroxyphenylacetate is a polyphenol that has been found inI. aquifoliumseeds and has antioxidant and antiviral activities.1,2It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50= 0.0025 mg/ml).1Methyl 3,4-dihydroxyphenylacetate (0.01 μg/ml) inhibits enterovirus 71 replication in rhabdomyosarcoma cells.2 1.Nahar, L., Russell, W.R., Middleton, M., et al.Antioxidant phenylacetic acid derivatives from the seeds of Ilex aquifoliumActa Pharm.55(2)187-193(2005) 2...

化合物

Candesartan Cilexetil

Cat.No: T2400

Synonym: TCV-116,坎地沙坦酯,坎地沙坦西酯

Target: Apoptosis, RAAS

1H-1-ethyl Candesartan Cilexetil

Cat.No: T21591

Target: Others

Cat.No: T25174

Synonym: Brassilexine

Cat.No: T124123

20-hydroxy Arachidic Acid

Cat.No: T35705

Methyl 3,4-Dihydroxyphenylacetate

Cat.No: T36174

Cat. No.	Product Name	Target	Signaling Pathways
T2S0501	Ilexgenin A	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	Ilexgenin A 是一种五环三萜类化合物，提取自海南冬青，可用于研究炎症及癌症。
T2S0504	Ilexoside D	Others	Others
	Ilexoside D has ant-allergic, and anti-coagulant activities, it shows anti-tissue factor activity as well as the antithrombotic activity.
T2S0500	Ilexsaponin A 毛冬青皂苷A,毛冬青皂苷甲,Ilexsaponin A1	Others	Others
	Ilexsaponin A (Ilexsaponin A1)1 是分离自冬凌草的根中，利用抗凋亡途径减轻缺血再灌注引起的心肌损伤。它能够减少心肌梗塞的大小，减少 LDH，AST 和 CK-MB 的血清水平，促进细胞活力并抑制缺氧/复氧心肌细胞的凋亡。
TN1474	Caulilexin C 板蓝根,1-甲氧基-3-吲哚乙腈	Others; Antifungal	Microbiology/Virology; Others
	Caulilexin C 是一种来自十字花科植物的植物抗毒素，具有抗真菌活性。
TJS0502	Ilexsaponin B2
	Ilexsaponin B2 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TJS0502，CAS号为 108906-69-0。
TN1763	Ilexsaponin B3 冬青苷K,Ilexoside K	Others	Others
	Ilexoside K is a natural product from Ilex pubescens.
T38777	Ilexoside O
	Ilexoside O, a triterpene saponin derived from Ilex pubescens roots, demonstrates modest inhibition of xanthine oxidase (XOD) activity with an IC50 value of 53.05 μM.
TN2421	Ilexgenin B	Others	Others
	Ilexgenin B is a natural product from Ilex chinensis Sims
T75696	Ilexoside XLVIII
	Ilexoside XLVIII为一种三萜皂苷，自苦冬青叶片水提物分离而得，功能为抑制酰基辅酶A胆固醇酰基转移酶（ACAT）。
TN1762	Ilexhainanoside D	Others	Others
	Ilexhainanoside D is a natural product from Periploca sepiumBge.
T2824	Pedunculoside	Others; Fatty Acid Synthase	Metabolism; Others
	Pedunculoside 是从 Ilex rotunda Thunb 中提取的，通过对脂质形成和脂肪酸 β-氧化的调节而发挥降脂作用。
T3S0208	Hederagenin 28-O-beta-D-glucopyranosyl ester Hederagenin-28-beta-D-glucopyranoside,常春苷元-28-BETA-D-吡喃葡萄糖苷,常春藤皂苷元28-O-beta-D-吡喃葡萄糖酯	Others	Others
	Hederagenin-28-beta-D-glucopyranoside 是一种分离自 Ilex cornuta 中的三萜皂苷，能够保护H2O2诱导的心肌细胞免于损伤。
TN1836	Kudinoside D	LDL; AMPK; PPAR	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism; PI3K/Akt/mTOR signaling
	Kudinoside D 是 Ilex kudingcha 中三萜皂苷的主要天然成分之一。它能够调节 3T3-L1 脂肪细胞中 AMPK 途径，并可抑制脂肪形成。
TN4081	Fraxiresinol 1-O-glucoside	Others	Others
	Fraxiresinol 1-O-glucoside is a natural product from Ilex pubescens.
TN5962	Rotundanonic acid
	Rotundanonic acid is a natural product from Ilex Rotunda.
T39107	5-O-(3'-O-Glucosylcaffeoyl)quinic acid
	5-O-(3'-O-Glucosylcaffeoyl)quinic acid (compound 19) is a phenolic compound primarily located in the leaves of Ilex glabra L. Gray (Aquifoliaceae).
T3S0507	Homovanillic acid Homovaniuic acid,Vanilacetic acid,高香草酸,Vanillacetic acid	Others; Endogenous Metabolite	Metabolism; Others
	Homovanillic acid (Vanillacetic acid) 是一种多巴胺代谢物，它与乳糜泻、生长激素缺乏、芳香族氨基酸脱羧酶缺乏症以及脂联素还原酶缺乏症相关。
TN2985	30-Oxolupeol	Others	Others
	30-Oxolupeol是一种天然产物，属于冬青科冬青属，其产品编号为 TN2985，CAS号为 64181-07-3。30-Oxolupeol可用作对照参考。
T5S0506	Rotundic acid Rutundic acid,铁冬青酸	Apoptosis; Others; p38 MAPK; Akt; mTOR	Apoptosis; Cytoskeletal Signaling; MAPK; Others; PI3K/Akt/mTOR signaling
	Rotundic acid (Rutundic acid) 是一种从圆形肠球菌中获得的三萜类天然产物，具有抗炎和保护心脏的能力。它可通过 AKT/mTOR 和 MAPK 途径在肝细胞癌中诱导 DNA 损伤和细胞凋亡。
TN4943	Sanguisorbigenin 地榆皂苷元,Tomentosolic acid,3β-Hydroxyurs-12,19-dien-28-oic acid,19-Dehydroursolic acid,Ursa-12,19-dien-28-oic acid	Antibacterial	Microbiology/Virology
	Sanguisorbigenin (Tomentosolic acid) 抑制耐甲氧西林金黄色葡萄球菌，是一种天然抗菌剂。
T3819	Ursolic acid acetate 熊果酸乙酸酯,Acetylursolic acid,3-Acetylursolic Acid	AChE	Neuroscience
	Ursolic acid acetate (Acetylursolic acid) 分离于 Ficus microcarpa 的气根中，对 KB 细胞显示细胞毒性(IC50:8.4 μM)。

天然产物

Cat.No: T2S0501

Target: IL Receptor, TNF

Cat.No: T2S0504

Target: Others

Ilexsaponin A

Cat.No: T2S0500

Synonym: 毛冬青皂苷A,毛冬青皂苷甲,Ilexsaponin A1

Target: Others

Cat.No: TN1474

Synonym: 板蓝根,1-甲氧基-3-吲哚乙腈

Target: Others, Antifungal

Ilexsaponin B2

Cat.No: TJS0502

Ilexsaponin B3

Cat.No: TN1763

Synonym: 冬青苷K,Ilexoside K

Target: Others

Cat.No: T38777

Cat.No: TN2421

Target: Others

Ilexoside XLVIII

Cat.No: T75696

Ilexhainanoside D

Cat.No: TN1762

Target: Others

Cat.No: T2824

Target: Others, Fatty Acid Synthase

Hederagenin 28-O-beta-D-glucopyranosyl ester

Cat.No: T3S0208

Synonym: Hederagenin-28-beta-D-glucopyranoside,常春苷元-28-BETA-D-吡喃葡萄糖苷,常春藤皂苷元28-O-beta-D-吡喃葡萄糖酯

Target: Others

Cat.No: TN1836

Target: LDL, AMPK, PPAR

Fraxiresinol 1-O-glucoside

Cat.No: TN4081

Target: Others

Rotundanonic acid

Cat.No: TN5962

5-O-(3'-O-Glucosylcaffeoyl)quinic acid

Cat.No: T39107

Homovanillic acid

Cat.No: T3S0507

Synonym: Homovaniuic acid,Vanilacetic acid,高香草酸,Vanillacetic acid

Target: Others, Endogenous Metabolite

Cat.No: TN2985

Target: Others

Cat.No: T5S0506

Synonym: Rutundic acid,铁冬青酸

Target: Apoptosis, Others, p38 MAPK, Akt, mTOR

Sanguisorbigenin

Cat.No: TN4943

Synonym: 地榆皂苷元,Tomentosolic acid,3β-Hydroxyurs-12,19-dien-28-oic acid,19-Dehydroursolic acid,Ursa-12,19-dien-28-oic acid

Target: Antibacterial

Ursolic acid acetate

Cat.No: T3819

Synonym: 熊果酸乙酸酯,Acetylursolic acid,3-Acetylursolic Acid

Target: AChE

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