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代谢 微生物学 神经科学 NF-κB信号通路 氧化还原 PI3K/Akt/mTOR信号通路 蛋白酶体
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细胞因子和生长因子 •   细胞因子 •   生长因子 受体蛋白 •   Fc 受体 •   细胞因子和生长因子受体
CD 蛋白 •   T 细胞 CD 蛋白 •   B 细胞 CD 蛋白 免疫检查点蛋白 •   抑制性免疫检查点蛋白 •   刺激性免疫检查点蛋白
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搜索结果

Search Results for " her3 "
Targets Recommended: Others

16

抑制剂 & 化合物

22

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T13841 PROTAC Her3-binding moiety 1

Others Others
PROTAC Her3-binding moiety 1 is a Her3 Ligand for PROTAC.
T77910 Patritumab deruxtecan

U3-1287,HER3-DXd
Patritumab deruxtecan (HER3-DXd)为一抗体-药物偶联物（ADC），其结构为全人源IgG1单克隆抗体Patritumab通过含四肽的裂解性连接子与拓扑异构酶 I 抑制剂药效团相连。
T77976 PROTAC Her3 Degrader-8

PROTACs PROTAC
PROTACHer3 Degrader-8（Compound PP2）是一类PROTAC，能在体外及细胞实验中降解Her3蛋白，适用于HER家族蛋白调控的疾病研究。
T17182 TX1-85-1

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
TX1-85-1 是不可逆 Her3 抑制剂，IC50值为 23 nM。它诱导 Her3 蛋白部分降解，并减弱 Her3 依赖性信号传导。它是选择性 Her3 配体，与位于 Her3 的 ATP 结合位点的 Cys721 形成共价键。
T76796 Patritumab

U3-1287,AMG-888

 ERK; EGFR; Akt; HER Angiogenesis; Cytoskeletal Signaling; JAK/STAT signaling; MAPK; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
Patritumab（U3-1287）是抗 HER3 单克隆抗体，具有潜在的抗肿瘤活性，对 EGFR，HER2，HER3，ERK 和 AKT 的磷酸化有抑制作用和。Patritumab 促使细胞凋亡 (apoptosis)，抑制非小细胞肺癌的增殖。
T7819 TAS0728

EGFR; HER Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
TAS0728 是一种 HER2 抑制剂，与HER2的 C805 位点共价结合，IC50值为 13 nM。它抑制 HER2、HER3 及其下游效应蛋白的磷酸化，具有抗肿瘤活性。
T72075 HyT36

HyT36 是一种小分子疏水标签，可选择性的破坏稳定，促进融合蛋白和假激酶 Her3 的降解。HyT36可治疗表达 erht 的细胞诱导急性。
T29024 TX2-121-1

TX 21211,TX 2-121-1
TX2-121-1 targets HER3 for proteasome-mediated degradation to inhibit HER3-dependent signalling and growth.
T76818 Lumretuzumab

Lumretuzumab (Anti-Human ERBB3 Recombinant Antibody)为人源化抗HER3 (ERBB3)单克隆抗体，应用于癌症研究。
T77047 Izalontamab

Izalontamab (SI-B001) 是双特异性抗EGFR/HER3单克隆抗体，高度选择性针对EGFR/HER3异源二聚体，用于癌症研究。
T77176 Elgemtumab

Elgemtumab(LJM716) 是一种全人IgG 单克隆抗体。Elgemtumab 可特异性结合 HER3，阻断配体依赖性和非依赖性 HER3 信号转导和细胞增殖，具有良好的抗肿瘤潜力。
T81679 Nezutatug

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Nezutatug为抗HER3抗体，在癌症研究中应用。
T76948 Zenocutuzumab

Zenocutuzumab (MCLA-128) 为一种双特异性人源化IgG1 抗体，其包含靶向HER2及HER3细胞外结构域的两个不同Fab臂。
T80604 Duligotuzumab

RG 7597,MEHD-7945A

 EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Duligotuzumab (MEHD-7945A; RG 7597)为一种人源化IgG-κ单克隆抗体，具有针对Her3 (ErbB3) 的特异性靶向能力。
T5398 BMS 599626 2HCl (873837-23-1(HCl))

AC480 dihydrochloride

 HER Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
BMS 599626 2HCl (873837-23-1(HCl)) (AC480 dihydrochloride) 是 HER1 和 HER2 的选择性抑制剂（IC50：20 nM 和 30 nM），对 HER4 的效力降低约 8 倍，对 Lck、VEGFR2、c-Kit、MET 等的效力降低 100 倍以上。
T76791 Seribantumab

Seribantumab (MM 121) 是一种完全人 IgG2单克隆抗体，靶向 HER3。Seribantumab 阻断 ErbB 家族成员及其下游信号的激活。Seribantumab 在体内、外抑制乳腺癌、肺癌和卵巢癌患者源性癌症模型中神经调节蛋白 (NRG1) 融合依赖的肿瘤发生。

化合物

PROTAC Her3-binding moiety 1
Cat.No: T13841
Synonym:
Target: Others
Patritumab deruxtecan
Cat.No: T77910
Synonym: U3-1287,HER3-DXd
Target:
PROTAC Her3 Degrader-8
Cat.No: T77976
Synonym:
Target: PROTACs
TX1-85-1
Cat.No: T17182
Synonym:
Target: EGFR
Patritumab
Cat.No: T76796
Synonym: U3-1287,AMG-888
Target: ERK, EGFR, Akt, HER
TAS0728
Cat.No: T7819
Synonym:
Target: EGFR, HER
HyT36
Cat.No: T72075
Synonym:
Target:
TX2-121-1
Cat.No: T29024
Synonym: TX 21211,TX 2-121-1
Target:
Lumretuzumab
Cat.No: T76818
Synonym:
Target:
Izalontamab
Cat.No: T77047
Synonym:
Target:
Elgemtumab
Cat.No: T77176
Synonym:
Target:
Nezutatug
Cat.No: T81679
Synonym:
Target: EGFR
Zenocutuzumab
Cat.No: T76948
Synonym:
Target:
Duligotuzumab
Cat.No: T80604
Synonym: RG 7597,MEHD-7945A
Target: EGFR
BMS 599626 2HCl (873837-23-1(HCl))
Cat.No: T5398
Synonym: AC480 dihydrochloride
Target: HER
Seribantumab
Cat.No: T76791
Synonym:
Target:
Species：
Human (12)
Rhesus (4)
Mouse (3)
Rat (2)
Cynomolgus,Rhesus (1)
Expression System：
HEK293 Cells (21)
Baculovirus Insect Cells (1)
Tag：
C-hFc (4)
His (4)
His, Avi (3)
C-His (2)
C-His-Avi (2)
Tag Free (2)
hFc (2)
C-6xHis-Avi (1)
His, GST (1)
mFc (1)
Cat. No. Product Name Species Expression System
TMPY-02365 HER3/ERBB3 Protein, Mouse, Recombinant (His)

Erbb-3r,Erbb3r,erb-b2 receptor tyrosine ki...

 Mouse HEK293 Cells
HER3/ERBB3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70 kDa and the accession number is Q61526.
TMPY-00399 HER3/ERBB3 Protein, Human, Recombinant

LCCS2,c-erbB-3,HER3,p180-ErbB...

 Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 69.3 kDa and the accession number is P21860-1.
TMPY-01389 HER3/ERBB3 Protein, Human, Recombinant (His)

MDA-BF-1,EEBB3,erbB3-S,p45-sErbB3...

 Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1.
TMPY-04956 HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated

MDA-BF-1,c-erbB-3,HER3,p85-sErbB<...

 Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1.
TMPJ-00899 HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)

HER3,Proto-oncogene-like protein c-ErbB-

Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 65 KDa and the accession number is P21860-3.
TMPY-00246 HER3/ERBB3 Protein, Rhesus, Recombinant

erb-b2 receptor tyrosine kinase 3

 Rhesus HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 69.5 kDa and the accession number is XP_001113953.2.
TMPY-03024 HER3/ERBB3 Protein, Rat, Recombinant (His)

erb-b2 receptor tyrosine kinase 3

 Rat HEK293 Cells
HER3/ERBB3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.9 kDa and the accession number is A6KSF8.
TMPY-02477 HER3/ERBB3 Protein, Rhesus, Recombinant (His)

erb-b2 receptor tyrosine kinase 3

 Rhesus HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.1 kDa and the accession number is XP_005571238.1&XP_001113953.2.
TMPJ-00413 HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated

Proto-oncogene-like protein c-ErbB-3,HER

Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 90-120 KDa and the accession number is P21860.
TMPY-06658 HER3/ERBB3 Protein, Mouse, Recombinant (hFc)

Erbb3,C76256,Erbb-3,erb-b2 receptor tyrosi...

 Mouse HEK293 Cells
HER3/ERBB3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.23 kDa and the accession number is Q61526.
TMPY-06659 HER3/ERBB3 Protein, Mouse, Recombinant (His & Avi), Biotinylated

C76256,Her3,Erbb-3,Erbb3...

 Mouse HEK293 Cells
HER3/ERBB3 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 71.76 kDa and the accession number is Q61526.
TMPK-00453 HER3/ERBB3 Protein, Human, Recombinant (His & Avi)

p45-sErbB3,MDA-BF-1,ErbB-3,HER

Human HEK293 Cells
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession number is P21860-1.
TMPY-03761 HER3/ERBB3 Protein, Human, Recombinant (mFc)

c-erbB-3,c-erbB3,HER3,er...

 Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 95 kDa and the accession number is P21860-1.
TMPK-01280 HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

p85-sErbB3,HER3,LCCS2,p180-ErbB

Cynomolgus,Rhesus HEK293 Cells
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.54 kDa and the accession number i...
TMPY-00795 HER3/ERBB3 Protein, Human, Recombinant (hFc)

HER3,c-erbB-3,p180-ErbB3...

 Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.4 kDa and the accession number is P21860-1.
TMPK-00452 HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled

LCCS2,HER3c-erbB-3,p180-ErbB3...

 Human HEK293 Cells
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession numbe...
TMPY-05753 HER3/ERBB3 Protein, Human, Recombinant (hFc), Biotinylated

HER3,p180-ErbB3,MDA-BF-1,erbB...

 Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.4 kDa and the accession number is P21860-1.
TMPY-06631 HER3/ERBB3 Protein, Human, Recombinant (His & Avi), Biotinylated

c-erbB3,MDA-BF-1,ErbB-3,erbB3-S,c...

 Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 71.93 kDa and the accession number is NP_001973.2.
TMPY-04541 HER3/ERBB3 Protein, Human, Recombinant (aa 730-1065, His & GST)

c-erbB3,ErbB-3,p45-sErbB3,LCCS2,p...

 Human Baculovirus Insect Cells
HER3/ERBB3 Protein, Human, Recombinant (aa 730-1065, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 65 kDa and the accession number is P21860-1.
TMPY-03023 HER3/ERBB3 Protein, Rat, Recombinant (hFc)

erb-b2 receptor tyrosine kinase 3

 Rat HEK293 Cells
HER3/ERBB3 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.5 kDa and the accession number is A6KSF8.
TMPY-02478 HER3/ERBB3 Protein, Rhesus, Recombinant (hFc)

erb-b2 receptor tyrosine kinase 3

 Rhesus HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.7 kDa and the accession number is XP_001113953.2.
TMPY-06660 HER3/ERBB3 Protein, Rhesus, Recombinant (His & Avi), Biotinylated

erb-b2 receptor tyrosine kinase 3

 Rhesus HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 71.92 kDa and the accession number is XP_001113953.2.

重组蛋白

HER3/ERBB3 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02365
Species: Mouse
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant
Cat.No: TMPY-00399
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01389
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04956
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)
Cat.No: TMPJ-00899
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant
Cat.No: TMPY-00246
Species: Rhesus
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03024
Species: Rat
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-02477
Species: Rhesus
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated
Cat.No: TMPJ-00413
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-06658
Species: Mouse
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06659
Species: Mouse
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00453
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03761
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
Cat.No: TMPK-01280
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00795
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled
Cat.No: TMPK-00452
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05753
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06631
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (aa 730-1065, His & GST)
Cat.No: TMPY-04541
Species: Human
Expression System: Baculovirus Insect Cells
HER3/ERBB3 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03023
Species: Rat
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-02478
Species: Rhesus
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06660
Species: Rhesus
Expression System: HEK293 Cells
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