11
2
40
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T31544 |
DL8F11
DL8F 11,DL8 F11,DL-8F11,DL8-F11,DL 8F11 |
||
DL8F11 is a biochemical. | |||
T77745 |
N6F11
|
GPX | oxidation-reduction |
N6F11是一种新型且具有选择性和有效性的铁死亡诱导剂,具有抗癌抗肿瘤活性,通过与癌细胞中的TRIM25结合从而促进GPX4降解。N6F11 可用于研究胰腺癌。 | |||
T13324 |
VUF11207 fumarate
|
CXCR; Arrestin | Autophagy; GPCR/G Protein; Immunology/Inflammation |
VUF11207 fumarate 是一种 CXCR7激动剂和高效CXCR7配体,pKi 为 8.1。它可诱导CXCR7的β-arrestin2募集和随后的内在化,pEC50分别为 8.8 和 7.9。 | |||
T75782 |
LF11 TFA
|
||
LF11 TFA 是一种具有抗菌 (antibacterial) 活性的肽。 | |||
T27860 |
Lu-AF11205
|
||
Lu-AF11205 is a potent positive allosteric modulator (PAM) of mGlu5 receptor. | |||
T66657 |
VUF11207 trifluoroacetate salt
|
||
VUF11207 trifluoroacetate salt 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66657,CAS号为 1378524-41-4。 | |||
T69921 |
BRF110
|
||
BRF110 is a brain penetrant, potent and selective agonist of nuclear receptor-related 1 (Nurr1):Retinoid X receptor α (RXRα) heterodimer. BRF110 is a neuroprotective agent that prevents dopaminergic neuron demise and striatal dopaminergic denervation in vivo against PD-causing toxins. It induced dopamine biosynthesis in vivo. BRF110 chronic dosing does not induce dyskinesia in mice model. | |||
T16875 |
SF1126
|
Others | Others |
SF1126 is a relevant pan and dual first-in-class PI3K/BRD4 inhibitor. SF1126 is an RGDS-conjugated LY294002 prodrug, which is designed to exhibit increased solubility and bind to specific integrins within the tumor compartment. | |||
T23656 |
VUF11211
VUF-11211,VUF 11211 |
||
VUF11211 is an effective antagonist of CXCR3 that acts by extending from the minor pocket into the major pocket of the transmembrane domains. | |||
TP2266 |
LF11
LF 11 |
Others | Others |
LF11 displays antimicrobial activity. | |||
TP2273 |
NF110
NF 110 |
Others | Others |
P2X3 antagonist |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3920 |
Pseudoginsenoside F11
Ginsenoside A1,拟人参皂苷 F11,拟人参皂苷F11 |
Others; Endogenous Metabolite | Metabolism; Others |
Pseudoginsenoside F11 (Ginsenoside A1) 从人参根和叶中分离得到。PF11在一系列心血管和中枢神经系统疾病中具有广泛的保护作用。 | |||
T19329 |
Fructo-oligosaccharide DP12/GF11
蔗果十二糖 |
Others | Others |
Fructo-oligosaccharide DP12/GF11 is a member of fructooligosaccharides (FOS) characterized by a degree of polymerization (DP) of 12. FOS compounds consist of 11 fructose units connected by (2→1)-β-glycosidic bonds, with a lone D-glucosyl unit located at the non-reducing end. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01104 |
Coagulation factor XI/F11 Protein, Human, Recombinant (His)
coagulation factor 11,coagulation factor XI,FXI |
Human | HEK293 Cells |
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the presence of calcium ions. It is an unusual dimeric protease, with structural features that distinguish it from vitamin K-dependent coagulation proteases. The factor XI is synthesized in the liver as a single polypeptide chain with a molecular weight estimated between 125 ~160 kDa ... | |||
TMPY-03161 |
JAM-A Protein, Rat, Recombinant (His)
F11 receptor |
Rat | HEK293 Cells |
JAM-A Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.3 kDa and the accession number is Q9JHY1. | |||
TMPY-03000 |
JAM-A Protein, Rat, Recombinant (hFc)
F11 receptor |
Rat | HEK293 Cells |
JAM-A Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.9 kDa and the accession number is Q9JHY1. | |||
TMPH-03268 |
Coagulation factor XI Protein, Rat, Recombinant (His & Myc)
Coagulation factor XI,F11 |
Rat | E. coli |
Coagulation factor XI Protein, Rat, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPK-01271 |
Coagulation factor XI Protein, Cynomolgus, Recombinant (His)
F11,PTA,FXI,Coagulation factor XI |
Cynomolgus | HEK293 Cells |
Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS). | |||
TMPY-01035 |
JAM-A Protein, Human, Recombinant (His)
PAM-1,F11 receptor,JAMA,JAM1,KAT,CD321,JCAM,JAM |
Human | HEK293 Cells |
JAM-A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is Q9Y624-1. | |||
TMPY-00865 |
JAM-A Protein, Human, Recombinant (hFc)
F11 receptor,JAM1,JAMA,KAT,CD321,JCAM,JAM,PAM-1 |
Human | HEK293 Cells |
JAM-A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50 kDa and the accession number is Q9BQB4-1. | |||
TMPY-01788 |
JAM-A Protein, Mouse, Recombinant (hFc)
ESTM33,F11 receptor,JAM,JAM-A,JAM-1,Ly106,Jcam,Jcam... |
Mouse | HEK293 Cells |
JAM-A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.2 kDa and the accession number is O88792. | |||
TMPK-00188 |
JAM-A Protein, Mouse, Recombinant (His)
F11R,JCAM1,PAM-1,PAM-1KAT,JAM-1,JAM,JCAM,JAM-A,KAT,... |
Mouse | HEK293 Cells |
junctional adhesion molecule A (JAM-A), a cell adhesion molecule, is highly elevated in human GBM cancer stem cells and predicts poor patient prognosis. While JAM-A is also highly expressed in other cells in the tumor microenvironment, specifically microglia and macrophages,JAM-A functions to suppress pathogenic microglial activation in the female tumor microenvironment, highlighting an emerging role for sex differences in the GBM microenvironment and suggesting that sex differences extend beyon... | |||
TMPY-03364 |
RANKL/TNFSF11/CD254 Protein, Human, Recombinant
sOdf,OPTB2,TNFSF11,TRANCE,hRANKL2,ODF,OPGL,RANKL,tu... |
Human | HEK293 Cells |
RANKL/TNFSF11/CD254 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.5 kDa and the accession number is AAC51762.1. | |||
TMPJ-00662 |
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)
Receptor activator of nuclear factor kappa-B ligand,Receptor... |
Human | E. coli |
CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL is the ligand of nuclear factor (NF)-κB (RANK). When RANKL binds to RANK, it will undergo trimerization and then bind to an adaptor molecule TNF receptor-associated factor 6 (TRAF6). This results in the activation of several downstream signaling cascades, including the NFκB, mitog... | |||
TMPY-03674 |
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (mFc)
sOdf,tumor necrosis factor (ligand) superfamily, member 11,T... |
Human | HEK293 Cells |
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 52.4 kDa and the accession number is AAC51762.1. | |||
TMPJ-00607 |
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)
Receptor activator of nuclear factor κ-B ligand,Osteoprotege... |
Mouse | HEK293 Cells |
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 30-35 KDa and the accession number is BAA97257.1. | |||
TMPY-02292 |
IGSF11 Protein, Human, Recombinant (His)
CT119,immunoglobulin superfamily, member 11,BT-IgSF,Igsf13,C... |
Human | HEK293 Cells |
Immunoglobulin superfamily member 11(IGSF11) is expressed on the plasma membrane in the testis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions. In clinical, the IGSF11 has been reported to overexpressed in colorectal cancers and hep... | |||
TMPY-02726 |
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc)
RANKL,OPGL,Trance,OPG,tumor necrosis factor (ligand) superfa... |
Mouse | HEK293 Cells |
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56 kDa and the accession number is AAC40113.1. | |||
TMPY-04142 |
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
OPTB7,OFE,OSTS,LOH18CR1,FEO,TRANCER,tumor necrosis factor re... |
Human | HEK293 Cells |
RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3. | |||
TMPK-00716 |
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244)
OPGL,TRANCE,OPTB2,TNFSF11,ODF,sOdf,RANKL,CD254 |
Human | HEK293 Cells |
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Human, Recombinant ... | |||
TMPJ-00273 |
IGSF11 Protein, Human, Recombinant (hFc)
CXADRL1,BT-IgSF,CT119,Igsf13,VSIG3 |
Human | HEK293 Cells |
Immunoglobulin superfamily member 11(IGSF11) is abundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle.IGSF11 functions as a cell adhesion molecule through homophilic interaction and can also stimulates cell growth.IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions. | |||
TMPJ-01472 |
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His)
|
Mouse | HEK293 Cells |
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 23-29 KDa and the accession number is O35235-1. | |||
TMPY-03026 |
RANK/TNFRSF11A Protein, Rat, Recombinant (hFc)
TNFRSF11A,tumor necrosis factor receptor superfamil... |
Rat | HEK293 Cells |
RANK/TNFRSF11A Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.1 kDa and the accession number is F1M8Z6. | |||
TMPK-00351 |
RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc)
NF-KB,ODFR,PDB2,Rank,OSTS,NFKB,OPTB7,TNFRSF11A,LOH1... |
Human | HEK293 Cells |
TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in gliomas, which affects apoptotic activity and focus formation thereby contributing to the molecular pathogenesis of gliomas. RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.85 kDa ... | |||
TMPJ-00674 |
RANK/TNFRSF11A Protein, Mouse, Recombinant (His)
Receptor activator of NF-KB,TNFRSF11A,Osteoclast di... |
Mouse | HEK293 Cells |
Receptor activator of NF-κB(RANK,TNFRSF11A) belongs to one member of tumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acids (aa) signal peptide, 184 aa extracellular region , a 20 aa transmembrane domain and a 391 aa cytoplasmic region. Human and murine RANK share 81% aa identity in their extracellular domains. RANK is ubiquitous highly expressed in trabecular bone, thymus, small intestine, lung, br... | |||
TMPK-00591 |
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)
CD254,OPGL,TNFSF11,TRANCE,ODF,sOdf,OPTB2,RANKL |
Mouse | HEK293 Cells |
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant ... | |||
TMPH-02960 |
TNFSF11 Protein, Mouse, Recombinant (His & SUMO)
|
Mouse | E. coli |
TNFSF11 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.9 kDa and the accession number is O35235. | |||
TMPH-02050 |
RNF114 Protein, Human, Recombinant (GST)
|
Human | E. coli |
RNF114 Protein, Human, Recombinant (GST) is expressed in E. coli. | |||
TMPK-00798 |
IGSF11 Protein, Mouse, Recombinant (His)
Bt-IGSF,BtIGSF,IgSF11,VSIG3,Bt IGSF,CXADRL1,CT119 |
Mouse | HEK293 Cells |
Immunoglobulin superfamily member 11 (IgSF11), a homophilic adhesion molecule that preferentially expressed in the brain, is a dual-binding partner of the postsynaptic scaffolding protein PSD-95 and AMPA glutamate receptors (AMPARs). | |||
TMPK-00723 |
RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc)
CD265,Rank,FEO,ODFR,NF-KB,OSTS,TNFRSF11A,OPTB7,NFKB... |
Mouse | HEK293 Cells |
TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in gliomas, which affects apoptotic activity and focus formation thereby contributing to the molecular pathogenesis of gliomas. RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 47.0 kDa and the acce... | |||
TMPY-05514 |
RANK/TNFRSF11A Protein, Human, Recombinant (mFc)
OFE,RANK,OPTB7,FEO,tumor necrosis factor receptor superfamil... |
Human | HEK293 Cells |
RANK/TNFRSF11A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q9Y6Q6-3. | |||
TMPH-02264 |
TNFSF11 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. Induces osteoclastogenesis by activating multipl... | |||
TMPY-01471 |
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (hFc)
TRANCE,sOdf,CD254,hRANKL2,TNFSF11,ODF,OPTB2,tumor n... |
Human | HEK293 Cells |
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.9 kDa and the accession number is AAC51762.1. | |||
TMPY-01546 |
Influenza A H6N1 (A/northern shoveler/California/HKWF115/2007) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H6N1 | HEK293 Cells |
Influenza A H6N1 (A/northern shoveler/California/HKWF115/2007) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is B3RDB8. | |||
TMPH-01413 |
GDF11 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues. It is required for proper vertebral patterning and orofacial development. Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3. GDF11 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression... | |||
TMPY-03527 |
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc)
CD254,tumor necrosis factor (ligand) superfamily, member 11,... |
Human | HEK293 Cells |
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 47.9 kDa and the accession number is O14788-2. | |||
TMPJ-00349 |
RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)
CD265 antigen,FEO,TRANCER,ODFR,ODFROSTS,TRANCE R,TNFRSF1... |
Human | HEK293 Cells |
Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutive... | |||
TMPK-00717 |
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag)
OPGL,CD254,TRANCE,ODF,RANKL,TNFSF11,OPTB2,sOdf |
Human | HEK293 Cells |
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Human, Recombinant ... | |||
TMPY-04157 |
RANK/TNFRSF11A Protein, Human, Recombinant (His)
ODFR,OFE,CD265,PDB2,RANK,tumor necrosis factor receptor supe... |
Human | HEK293 Cells |
RANK/TNFRSF11A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.5 kDa and the accession number is Q9Y6Q6-3. | |||
TMPY-06561 |
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (rFc)
OPTB2,OPGL,hRANKL2,CD254,sOdf,tumor necrosis factor (ligand)... |
Human | HEK293 Cells |
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 46.18 kDa and the accession number is AAC51762.1. | |||
TMPY-00537 |
RANKL/TNFSF11/CD254 Protein, Cynomolgus, Recombinant (hFc)
tumor necrosis factor (ligand) superfamily, member 11 |
Cynomolgus | HEK293 Cells |
RANKL/TNFSF11/CD254 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.9 kDa and the accession number is G7PW41. | |||
TMPY-01629 |
Influenza A H6N1 (A/northern shoveler/California/HKWF115/2007) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H6N1 | HEK293 Cells |
Influenza A H6N1 (A/northern shoveler/California/HKWF115/2007) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is B3RDB8. | |||
TMPY-02851 |
RANK/TNFRSF11A Protein, Rat, Recombinant (His)
tumor necrosis factor receptor superfamily member 11a,TNFRS<... |
Rat | HEK293 Cells |
RANK/TNFRSF11A Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.5 kDa and the accession number is F1M8Z6. |