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Search Results for " ar1 "

Targets Recommended: RAAS

17

抑制剂 & 化合物

19

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T7575L1	[Sar1, Ile8]-Angiotensin II acetate	RAAS	Endocrinology/Hormones
	[Sar1, Ile8]-Angiotensin II acetate 可激活 NADPH 和 NADH 氧化酶，并刺激血管平滑肌细胞中超氧阴离子的形成。 [Sar1, Ile8]-Angiotensin II acetate 对血管平滑肌有多种作用，包括正常动脉的收缩和培养细胞或病变血管的肥大或增生。
T5677	SAR125884 hydrochlorid (1116743-46-4(free base))	c-Met/HGFR	Tyrosine Kinase/Adaptors
	SAR125884 hydrochlorid (1116743-46-4(free base)) 是一种有效的选择性 MET 激酶抑制剂，具有良好的临床前毒性特征 (IC50=4.2 nM)。
T6012	SAR131675 SAR 131675	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	SAR131675 是一种选择性的VEGFR3抑制剂，其IC50=23 nM。
T11458	GPR40/FFAR1 modulator 1	GPR	Endocrinology/Hormones; GPCR/G Protein
	GPR40/FFAR1 modulator 1是一种针对Gq偶联的游离脂肪酸受体1 (GPR40/FFAR1) 的激动剂以及异构调节剂。
T7575L	[Sar1, Ile8]-Angiotensin II 3TFA [Sar1, Ile8]-Angiotensin II 3TFA(37827-06-8(free base))	Others	Others
	[Sar1, Ile8]-Angiotensin II 3TFA ([Sar1, Ile8]-Angiotensin II 3TFA (37827-06-8(free base))) 是一种对血管平滑肌具有多种作用的肽。
T5467	SAR125844 SAR125884	Apoptosis; c-Met/HGFR	Apoptosis; Tyrosine Kinase/Adaptors
	SAR125844 是高度选择性可逆ATP 竞争性的MET 受体酪氨酸激酶抑制剂，其IC50值为4.2 nM。能抑制细胞中MET 的自磷酸化。
T3691	(Rac)-SAR131675 SAR131675	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	(Rac)-SAR131675 是一种有效的、选择性的VEGFR3抑制剂，其IC50=23 nM。
T76634	(Sar1,Ile4,8)-Angiotensin II
	(Sar1,Ile4,8)-Angiotensin II是一种对angiotensin II type 1 receptor (AT1R)具有功能选择性的激动剂，能增强胰岛素受体 (IR) 信号和糖原合成，同时还能促进Akt和GSK3α/β的磷酸化，这一过程被胰岛素刺激所增强。
T24758	SAR127303 SAR-127303,SAR 127303
	SAR127303 is an effective covalent inhibitor of MAGL. SAR127303 behaves as a selective and competitive inhibitor of mouse and human MAGL.
T71112	SAR156497
	SAR156497 is an exquisitely selective Aurora A, B, and C inhibitor with in vitro and in vivo efficacy with IC50 = 0.5 nM (Aurora A); 1 nM (Aurora B / incenp); 3 nM (Aurora C / incenp) respectively SAR156497 combines high in vitro potency with satisfactory metabolic stability and limited CYP 3A4 and PDE3 inhibition. In vitro, SAR156497 displayed high antiproliferative activity on a large panel of tumor cell lines without correlation with any particular genetic signature or Aurora kinases expressi...
T60863	GPBAR1-IN-3
	GPBAR1-IN-3 (Compound 14) 是一种选择性 GPBAR1激动剂 (EC50=0.17 μM) 和 CysLT1R 拮抗剂。
T78263	Anti-Mouse IFNAR1 Antibody (MAR1-5A3)	IFNAR	Immunology/Inflammation
	Anti-MouseIFNAR1Antibody (MAR1-5A3) 为IFNAR1中和抗体，可在体内外与IFNAR1结合并阻断信号传导。MouseIgG1kappa, Isotype Control 作为 Anti-MouseIFNAR1Antibody (MAR1-5A3) 的同型对照使用。
T35834	(Sar1)-Angiotensin II (Sar¹)-Angiotensin II
	The substitution with Sar at position 1 of angiotensin II resulted in a partial agonistic activity.
T82797	C5aR1 antagonist peptide
	C5aR1 antagonist peptide 是一种源自C5a (趋化因子补体片段5过敏毒素) C末端的生物活性线性肽。它能在人和大鼠的C5a受体上阻断C5a的结合，对于细胞免疫反应的触发起着关键作用。C5a的过度表达与多种免疫炎性疾病如关节炎、阿尔茨海默病、囊性纤维化和系统性红斑狼疮等有着密切关联。
TP1224	[Sar1, Ile8]-Angiotensin II TFA Angiotensin 2 TFA,AngiotensinII TFA
	[Sar1, Ile8]-Angiotensin II (TFA) is a peptide compound that exerts various effects on vascular smooth muscle. These effects include the contraction of normal arteries as well as the hypertrophy or hyperplasia of cultured cells or diseased vessels.
T7575	[Sar1, Ile8]-Angiotensin II [Sar1, Ile8]-Angiotensin II(3TFA)	RAAS; Others	Endocrinology/Hormones; Others
	[Sar1, Ile8]-Angiotensin II 是一种在血管平滑肌细胞中有多种作用（如正常动脉的收缩，培养的细胞或病变血管的肥大或增生等）的多肽，。
T40471	Azophloxine Acid red 1,Azophloxine
	Azophloxine, also known as acid red 1 (AR1), is a member of synthetic red azo dye family.

化合物

[Sar1, Ile8]-Angiotensin II acetate

Cat.No: T7575L1

Target: RAAS

SAR125884 hydrochlorid (1116743-46-4(free base))

Cat.No: T5677

Target: c-Met/HGFR

Cat.No: T6012

Synonym: SAR 131675

Target: VEGFR

GPR40/FFAR1 modulator 1

Cat.No: T11458

Target: GPR

[Sar1, Ile8]-Angiotensin II 3TFA

Cat.No: T7575L

Synonym: [Sar1, Ile8]-Angiotensin II 3TFA(37827-06-8(free base))

Target: Others

Cat.No: T5467

Synonym: SAR125884

Target: Apoptosis, c-Met/HGFR

(Rac)-SAR131675

Cat.No: T3691

Synonym: SAR131675

Target: VEGFR

(Sar1,Ile4,8)-Angiotensin II

Cat.No: T76634

Cat.No: T24758

Synonym: SAR-127303,SAR 127303

Cat.No: T71112

Cat.No: T60863

Anti-Mouse IFNAR1 Antibody (MAR1-5A3)

Cat.No: T78263

Target: IFNAR

(Sar1)-Angiotensin II

Cat.No: T35834

Synonym: (Sar¹)-Angiotensin II

C5aR1 antagonist peptide

Cat.No: T82797

[Sar1, Ile8]-Angiotensin II TFA

Cat.No: TP1224

Synonym: Angiotensin 2 TFA,AngiotensinII TFA

[Sar1, Ile8]-Angiotensin II

Cat.No: T7575

Synonym: [Sar1, Ile8]-Angiotensin II(3TFA)

Target: RAAS, Others

Cat.No: T40471

Synonym: Acid red 1,Azophloxine

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03233	NKp46/NCR1 Protein, Rat, Recombinant (hFc) natural cytotoxicity triggering receptor 1,Kilr...	Rat	HEK293 Cells
	NKp46/NCR1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.1 kDa and the accession number is Q9Z0H5.
TMPK-00326	IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated IFN-alpha/β R1,IFN-α/β R1,IFN α/β R1	Human	HEK293 Cells
	IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.2 kDa and the accession number is P17181-1.
TMPK-00325	IFNAR1 Protein, Human, Recombinant (His & Avi) AVP,IFN-alpha-REC,IFN-α/β R1,IFNAR,IFN α/β...	Human	HEK293 Cells
	IFNAR1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.2 kDa and the accession number is P17181-1.
TMPK-00343	IFNAR1 Protein, Mouse, Recombinant (hFc) AVP,IFNBR,IFN-alpha/β R1,IFNAR,IFN-aR<...	Mouse	HEK293 Cells
	IFNAR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 72.5 kDa and the accession number is P33896.
TMPK-00342	IFNAR1 Protein, Mouse, Recombinant (His & Avi) IFN-α-REC,IFN-R-1,IFNAR1,IFN-alph...	Mouse	HEK293 Cells
	IFNAR1 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 46.9 kDa and the accession number is P33896.
TMPY-02647	IFNAR1 Protein, Human, Recombinant (His) interferon (alpha, beta and omega) receptor 1,IFN-α...	Human	HEK293 Cells
	IFNAR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.6 kDa and the accession number is P17181-1.
TMPY-02634	IFNAR1 Protein, Human, Recombinant (hFc) interferon (α, β and Ω) receptor 1,IFNBR,AVP,IFN-α-...	Human	HEK293 Cells
	IFNAR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 74 kDa and the accession number is P17181-1.
TMPY-01489	IFNAR1 Protein, Mouse, Recombinant (His) Ifrc,Ifar,CD118,interferon (α, β ...	Mouse	HEK293 Cells
	IFNAR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is P33896.
TMPY-05207	PRKAR1A Protein, Mouse, Recombinant (His) 1300018C22Rik,protein kinase, cAMP-depende...	Mouse	Baculovirus Insect Cells
	PRKAR1A Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 44.6 kDa and the accession number is Q9DBC7.
TMPH-01420	SAR1A Protein, Human, Recombinant (GST)	Human	E. coli
	Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES). SAR1A Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 49.4 kDa and the accession number...
TMPJ-00331	IFNAR1 Protein, Rhesus macaque, Recombinant (His) IFN-al,CRF2-1,IFN-alpha/beta receptor 1,hu...	Rhesus	HEK293 Cells
	Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphory...
TMPY-03656	PRKAR1A Protein, Human, Recombinant (His) PRKAR1,CAR,CNC1,PPNAD	Human	HEK293 Cells
	PRKAR1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is P10644.
TMPH-01022	C5AR1 Protein-VLP, Human, Recombinant (His) C5a anaphylatoxin chemotactic receptor 1,CD88,C5a a...	Human	HEK293 Cells
	Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. C5AR1 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-...
TMPH-01023	C5AR1 Protein, Human, Recombinant (Cell-Free, His) C5a anaphylatoxin chemotactic receptor 1,C5R1	Human	E. coli
	Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. C5AR1 Protein, Human, Recombinant (Cell-Free, His) is expressed in E. coli expression syst...
TMPH-00446	CCHF virus (strain Nigeria/IbAr10200/1970) Envelopment polyprotein (His & MBP) GP,Envelopment polyprotein,M polyprotein	CCHFV	E. coli
	CCHF virus (strain Nigeria/IbAr10200/1970) Envelopment polyprotein (His & MBP) is expressed in E. coli.
TMPY-03927	IFNAR1 Protein, Rhesus, Recombinant interferon (α, β and ω) receptor 1,interferon (alph...	Rhesus	HEK293 Cells
	IFNAR1 Protein, Rhesus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 48.3 kDa and the accession number is H9Z8H4.
TMPY-04254	IFNAR1 Protein, Rhesus, Recombinant (His) interferon (alpha, beta and omega) receptor 1,inter...	Rhesus	HEK293 Cells
	IFNAR1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.7 kDa and the accession number is H9Z8H4.
TMPY-03829	IFNAR1 Protein, Rhesus, Recombinant (hFc) interferon (α, β and Ω) receptor 1,interferon (alph...	Rhesus	HEK293 Cells
	IFNAR1 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 74.5 kDa and the accession number is H9Z8H4.
TMPY-00624	PEAR1 Protein, Rat, Recombinant (His) platelet endothelial aggregation receptor 1	Rat	Baculovirus Insect Cells
	Platelet endothelial aggregation receptor-1 (PEAR1), an epidermal growth factor repeat-containing transmembrane receptor, is known to participate in platelet contact-induced activation. Platelet endothelial aggregation receptor 1 (PEAR1) triggers platelet aggregation and is expressed in platelets and endothelial cells.PEAR1 encodes the Platelet-Endothelial Aggregation Receptor 1, a contact receptor involved in platelet function and megakaryocyte and endothelial cell proliferation. PEAR1 expressi...

重组蛋白

NKp46/NCR1 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-03233

Species: Rat

Expression System: HEK293 Cells

IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00326

Species: Human

Expression System: HEK293 Cells

IFNAR1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00325

Species: Human

Expression System: HEK293 Cells

IFNAR1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00343

Species: Mouse

Expression System: HEK293 Cells

IFNAR1 Protein, Mouse, Recombinant (His & Avi)

Cat.No: TMPK-00342

Species: Mouse

Expression System: HEK293 Cells

IFNAR1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02647

Species: Human

Expression System: HEK293 Cells

IFNAR1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02634

Species: Human

Expression System: HEK293 Cells

IFNAR1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01489

Species: Mouse

Expression System: HEK293 Cells

PRKAR1A Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05207

Species: Mouse

Expression System: Baculovirus Insect Cells

SAR1A Protein, Human, Recombinant (GST)

Cat.No: TMPH-01420

Species: Human

Expression System: E. coli

IFNAR1 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPJ-00331

Species: Rhesus

Expression System: HEK293 Cells

PRKAR1A Protein, Human, Recombinant (His)

Cat.No: TMPY-03656

Species: Human

Expression System: HEK293 Cells

C5AR1 Protein-VLP, Human, Recombinant (His)

Cat.No: TMPH-01022

Species: Human

Expression System: HEK293 Cells

C5AR1 Protein, Human, Recombinant (Cell-Free, His)

Cat.No: TMPH-01023

Species: Human

Expression System: E. coli

CCHF virus (strain Nigeria/IbAr10200/1970) Envelopment polyprotein (His & MBP)

Cat.No: TMPH-00446

Species: CCHFV

Expression System: E. coli

IFNAR1 Protein, Rhesus, Recombinant

Cat.No: TMPY-03927

Species: Rhesus

Expression System: HEK293 Cells

IFNAR1 Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-04254

Species: Rhesus

Expression System: HEK293 Cells

IFNAR1 Protein, Rhesus, Recombinant (hFc)

Cat.No: TMPY-03829

Species: Rhesus

Expression System: HEK293 Cells

PEAR1 Protein, Rat, Recombinant (His)

Cat.No: TMPY-00624

Species: Rat

Expression System: Baculovirus Insect Cells

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