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Search Results for " andrographis "

2

抑制剂 & 化合物

20

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T125901	14-Epiandrographolide
	14-Epiandrographolide 是从穿心莲地上部分提取到的化合物，可诱导细胞分化，可用于研究多发性硬化症。
T40971	Dehydroandrographolide succinate potassium sodium salt
	Dehydroandrographolide succinate (potassium sodium salt), derived from the herbal medicine Andrographis paniculata (Burm f) Nees, is a versatile compound highly utilized for the treatment of viral pneumonia and viral upper respiratory tract infections due to its potent immunostimulatory, anti-infective, and anti-inflammatory properties.

化合物

14-Epiandrographolide

Cat.No: T125901

Dehydroandrographolide succinate potassium sodium salt

Cat.No: T40971

Cat. No.	Product Name	Target	Signaling Pathways
T2898	Andrographolide Andrographis,穿心莲内酯	SARS-CoV; Influenza Virus; NF-κB; Autophagy	Autophagy; Microbiology/Virology; NF-κB
	Andrographolide (Andrographis) 是 NF-κB 的不可逆拮抗剂，具有抗病毒、抗炎和抗血小板聚集活性和潜在的抗肿瘤作用。
TN2622	14-Deoxy-11,12-didehydroandrographiside	Others	Others
	14-Deoxy-11,12-didehydroandrographiside是一种天然产物，属于爵床科穿心莲属，其产品编号为 TN2622，CAS号为 141973-41-3。14-Deoxy-11,12-didehydroandrographiside可用作对照参考。
TN3412	Andrographiside	Others	Others
	Andrographiside shows protective effects on hepatotoxicity induced in mice by carbon tetrachloride or tert-butylhydroperoxide (tBHP) intoxication, the effects could be due to its glucoside groups which may act as strong antioxidants.
TN1995	5,7,8-Trimethoxyflavone Norwogonin 5,7,8-trimethyl ether	NO Synthase	Immunology/Inflammation
	5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether) 是从穿心莲中提取的化合物，具有抗炎活性，对 NO 有抑制作用。
T8288	14-Deoxyandrographolide 去氧穿心莲内酯,14-去氧穿心莲内酯	Apoptosis; Others	Apoptosis; Others
	14-Deoxyandrographolide 是穿心莲中的一种天然产物，是一种钙通道阻断剂，具有保肝功效。它通过诱导 TNFRSF1A 的释放，使肝细胞对 TNF-α 介导的凋亡脱敏。
T9218	Andrograpanin 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE,新穿心莲内酯苷元	p38 MAPK	MAPK
	Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) 是来自穿心莲的一种天然产物，具有抗炎和抗感染活性。
T2738	Dehydroandrographolide	NOS; Influenza Virus	Immunology/Inflammation; Microbiology/Virology
	Dehydroandrographolide 是从草药穿心莲中提取的一种天然产物。它通过使 iNOS 失活来降低 LPS 诱导的急性肺损伤中的氧化应激，有抗感染活性。
T13582	Bisandrographolide C	Others	Others
	Bisandrographolide C is identified from Andrographis paniculata. Bisandrographolide C activates TRPV1 and TRPV3 channels (Kds: 289 and 341 μM) and protects cardiomyocytes from hypoxia-reoxygenation injury.
TN2463	14-Deoxy-11-oxoandrographolide	Others	Others
	14-Deoxy-11-oxoandrographolide is a natural product from Andrographis paniculata
TN3518	Bisandrographolide A	Others	Others
	Bisandrographolide A activates TRPV4 channels, could play a role in some of the effects of Andrographis extract described in traditional medicine.
TN3119	5-Hydroxy-7,8-dimethoxyflavanone	IL Receptor; TNF; NF-κB; HIV Protease; NO Synthase; CCR	Apoptosis; Immunology/Inflammation; Microbiology/Virology; NF-κB; Proteases/Proteasome
	5-Hydroxy-7,8-dimethoxyflavanone 是从穿心莲叶和根中分离出来的，具有抗炎活性。
TN1381	Andropanoside	Others	Others
	Andropanoside是一种天然产物，属于爵床科穿心莲属，其产品编号为 TN1381，CAS号为 82209-72-1。Andropanoside可用作对照参考。
TN2623	14-Deoxy-17-hydroxyandrographolide	Antifection	Microbiology/Virology
	14-Deoxy-17-hydroxyandrographolide是一种天然产物，属于爵床科穿心莲属，其产品编号为 TN2623，CAS号为 869384-82-7。14-Deoxy-17-hydroxyandrographolide可用作对照参考。
TN3411	Andrographidine C	Others	Others
	Andrographidine C是一种天然产物，属于爵床科穿心莲属，其产品编号为 TN3411，CAS号为 113963-39-6。Andrographidine C可用作对照参考。
TN5586	14-Deoxy-12-hydroxyandrographolide
	14-Deoxy-12-hydroxyandrographolide是一种天然产物，属于爵床科穿心莲属，其产品编号为 TN5586，CAS号为 219721-33-2。14-Deoxy-12-hydroxyandrographolide可用作对照参考。
TQ0073	Andropanolide	HIV Protease; NO Synthase; Parasite	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Andropanolide 是一种来自穿心莲的二帖类化合物，具有抗HIV、抗疟和抗癌活性，对 Lipopolysaccharides (LPS) 刺激的 RAW264.7 巨噬细胞中一氧化氮 (NO) 的过量产生有抑制作用。
TQ0185	14-Deoxy-11,12-didehydroandrographolide AP10,14-脱氧-11,12-二去氢穿心莲内酯,14-dehydro Andrographolide	NF-κB	NF-κB
	14-Deoxy-11,12-didehydroandrographolide (AP10) 是一种 Andrographolide 的类似物，能够抑制 NF-κB 活性。
T2S0257	Dehydroandrographolide succinate	Others; Influenza Virus	Microbiology/Virology; Others
	Dehydroandrographolide succinate 是从中药穿心莲中提取的一种天然产物，具有免疫刺激、抗感染和抗炎作用，有潜力研究病毒性肺炎和病毒性上呼吸道感染。
T8152	6-Demethoxytangeretin	MAPK; ALK	Angiogenesis; MAPK; Tyrosine Kinase/Adaptors
	6-Demethoxytangeretin 是一种从柑橘分离的黄酮。它能够促进 CRE 介导的转录 (与海马神经元的学习和记忆相关)。它具有抗炎和抗过敏作用，通过间变性淋巴瘤激酶和丝裂原活化蛋白激酶途径抑制人肥大细胞中 IL-6 的产生和基因表达。
TQ0218	Deoxyandrographolide 去氧穿心莲内酯,14-deoxyandrographolide	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	Deoxyandrographolide (14-deoxyandrographolide) 抑制 LPS 诱导的 iNOS mRNA 水平升高以及促炎症介质 TNF-α 和 IL-6 的产生。它增强 NGF 诱导的神经突起生长。

天然产物

Andrographolide

Cat.No: T2898

Synonym: Andrographis,穿心莲内酯

Target: SARS-CoV, Influenza Virus, NF-κB, Autophagy

14-Deoxy-11,12-didehydroandrographiside

Cat.No: TN2622

Target: Others

Andrographiside

Cat.No: TN3412

Target: Others

5,7,8-Trimethoxyflavone

Cat.No: TN1995

Synonym: Norwogonin 5,7,8-trimethyl ether

Target: NO Synthase

14-Deoxyandrographolide

Cat.No: T8288

Synonym: 去氧穿心莲内酯,14-去氧穿心莲内酯

Target: Apoptosis, Others

Cat.No: T9218

Synonym: 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE,新穿心莲内酯苷元

Target: p38 MAPK

Dehydroandrographolide

Cat.No: T2738

Target: NOS, Influenza Virus

Bisandrographolide C

Cat.No: T13582

Target: Others

14-Deoxy-11-oxoandrographolide

Cat.No: TN2463

Target: Others

Bisandrographolide A

Cat.No: TN3518

Target: Others

5-Hydroxy-7,8-dimethoxyflavanone

Cat.No: TN3119

Target: IL Receptor, TNF, NF-κB, HIV Protease, NO Synthase, CCR

Cat.No: TN1381

Target: Others

14-Deoxy-17-hydroxyandrographolide

Cat.No: TN2623

Target: Antifection

Andrographidine C

Cat.No: TN3411

Target: Others

14-Deoxy-12-hydroxyandrographolide

Cat.No: TN5586

Cat.No: TQ0073

Target: HIV Protease, NO Synthase, Parasite

14-Deoxy-11,12-didehydroandrographolide

Cat.No: TQ0185

Synonym: AP10,14-脱氧-11,12-二去氢穿心莲内酯,14-dehydro Andrographolide

Target: NF-κB

Dehydroandrographolide succinate

Cat.No: T2S0257

Target: Others, Influenza Virus

6-Demethoxytangeretin

Cat.No: T8152

Target: MAPK, ALK

Deoxyandrographolide

Cat.No: TQ0218

Synonym: 去氧穿心莲内酯,14-deoxyandrographolide

Target: IL Receptor, TNF

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