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Search Results for " a-6 peptide "

97

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T26629	Angstrom6 A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide	PAI-1	Metabolism
	Angstrom6 (A-6 peptide) 是一种从单链尿激酶纤溶酶原激活剂(scuPA)中提取的 8 肽，它能干扰 uPA/uPAR 级联反应并抑制下游效应。Angstrom6 具有抗肿瘤活性，能通过与 CD44 结合并调节 CD44 介导的细胞信号传导，抑制肿瘤细胞的迁移、侵袭和转移。
TP1422	Interleukin (IL)-6 Receptor	Others	Others
	Interleukin (IL)-6 Receptor 是一种肽，来源于白细胞介素6受体。
T38852L	TRAP-6 amide acetate	Protease-activated Receptor	GPCR/G Protein
	TRAP-6 amide acetate 是一种 PAR-1 凝血酶受体激动剂肽。
TP1579	Angiotensin I/II (1-6) Angiotensin I/II 1-6	RAAS; Others	Endocrinology/Hormones; Others
	Angiotensin I/II (1-6) 是由血管紧张素 I/II 肽转化而来，含有 1-6 个氨基酸的多肽。血管紧张素 I 被血管紧张素转换酶水解，形成具有生物活性的血管紧张素 II。血管紧张素 II 用于高血压、特发性膜性肾病和肾素-血管紧张素系统的研究。
TP1484L	α2β1 Integrin Ligand Peptide acetate α2β1 Integrin Ligand Peptide acetate (134580-64-6)	Integrin	Cytoskeletal Signaling
	α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) 是 α2β1 整合素受体的潜在拮抗剂。它与细胞膜上的 α2β1 整合素受体相互作用，介导细胞外信号进入细胞。
T21674L	PKA inhibitor fragment (6-22) amide Acetate PKA inhibitor fragment (6-22) amide Acetate(121932-06-7 Free base)	PKA	Tyrosine Kinase/Adaptors
	PKA inhibitor fragment (6-22) amide Acetate 是一种通过结合底物位点选择性抑制PKA 活性的合成肽(IC50 < 2 nM)。
T9280	CS-0047390 (S)-Di-tert-butyl 2-(3-((S)-6-amino-1-(tert-butoxy)-1-oxohexan-2-yl)ureido)pentanedioate	Others	Others
	CS-0047390 ((S)-Di-tert-butyl 2-(3-((S)-6-amino-1-(tert-butoxy)-1-oxohexan-2-yl)ureido)pentanedioate)又称 tert-Butyl-DCL，PSMA 抑制剂，是一种放射显影多肽试剂。
TP2047L	CRF (6-33) acetate(120066-38-8 free base)	CRFR	GPCR/G Protein
	CRF (6-33) acetate(120066-38-8 free base) 是促肾上腺皮质激素释放因子结合蛋白 (CRFBP) 抑制肽；从 CRFBP 中替换 CRF。在体内抑制肥胖大鼠的体重增加并增加运动活动。
TP1289	Cardiotoxin Analog (CTX) IV (6-12) TFA Cardiotoxin Analog (CTX) IV (6-12) (TFA)(115722-23-1,FREE)	Others	Others
	Cardiotoxin Analog (CTX) IV (6-12) TFA(115722-23-1 free base) 是 Cardiotoxin Analog (CTX) IV 的部分肽。从台湾眼镜蛇毒液中分离出的心脏毒素类似物 IV。 CTX IV 是一种独特的蛇毒心脏毒素。
TP1315	c-Myc Peptide Trifluoroacetate	Others	Others
	c-Myc Peptide Trifluoroacetate (145646-22-6 free base) 是一种合成肽，对应于人类 c-myc 蛋白的 C 末端氨基酸 (410-419)，参与调控生长相关基因的转录。
TP1866L	β-amyloid 1-11 acetate(190436-05-6 free base)	Beta Amyloid	Neuroscience
	β-amyloid 1-11 acetate(190436-05-6 free base) 是 Amyloid-β 肽的片段，可用于神经系统疾病的研究。
T8559	Galnon TFA(475115-35-6(free base))	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	GALNON TFA(475115-35-6(free base)) 是一种新型非肽甘丙肽受体激动剂（GAL1 和 GAL2，Ki 分别为 11.7 和 34.1 μM）。
TP1104L	Melanin Concentrating Hormone, salmon acetate MCH (salmon),Melanin Concentrating Hormone, salmon acetate(87218-84-6 free base)	Others; Melanin-concentrating Hormone Receptor (MCHR)	GPCR/G Protein; Others
	Melanin Concentrating Hormone, salmon acetate (MCH (salmon))(87218-84-6 free base) 是一种 19 个氨基酸的环状肽，主要在下丘脑中表达。
T21618L	Myelin Basic Protein (87-99) Acetate Myelin Basic Protein (87-99) Acetate (118506-26-6 Free base)	Others	Others
	Myelin Basic Protein (87-99) Acetate (Myelin Basic Protein (87-99) Acetate (118506-26-6 Free base)) 是一种致脑炎肽，可诱导碱性蛋白特异性 T 细胞增殖。它导致外周血单核细胞中的 Th1 极化，这与多发性硬化症 (MS) 有牵连。
TP1458L	Arg-Gly-Glu-Ser acetate(93674-97-6 free base)	Others	Others
	Arg-Gly-Glu-Ser acetate(93674-97-6 free base) 是一种 RGD 相关肽，可控制纤维蛋白原与活化血小板结合的 RGDS 活性。
TP1943L1	pep2-EVKI acetate(1315378-67-6 free base)	GluR	Neuroscience
	pep2-EVKI acetate(1315378-67-6 free base) 是一种细胞渗透性肽。它干扰与 C 激酶 (PICK1) 相互作用的蛋白质和 GluR2 AMPA 受体亚基之间的相互作用。
TP1605L1	Allatostatin IV TFA(123338-13-6 free base)	Others	Others
	Allatostatin IV TFA(123338-13-6 free base) 是一种八肽胺，是在昆虫中发现的抑制（allatostatins）或刺激（allatotropins）保幼激素（JH）合成的调节肽家族的成员。
TP1293	Jagged-1 (188-204) TFA(219127-21-6 free base) Jagged-1 (188-204) TFA	Gamma-secretase	Neuroscience; Proteases/Proteasome; Stem Cells
	Jagged-1 (188-204) TFA(219127-21-6 free base) 是 JAG-1 蛋白的一个片段。 JAG-1 是 Notch 配体，是一种在皮肤中表达最明显的肽。 JAG-1 诱导表皮成熟。将淹没的角质形成细胞单层暴露于钙浓度升高的 JAG-1 会产生具有 loricrin 表达和 NF-alphaB 激活的分层。
TP1606L	NLS PKKKRKV acetate(95088-49-6 free base)	Others	Others
	NLS PKKKRKV acetate(95088-49-6 free base) 是从大猿病毒40肿瘤抗原（SV40大T 抗原）衍生的肽，是基因转移研究领域中增强核入口的一种方法。
T15368L	Galantide acetate Galantide acetate(138579-66-5 Free base)	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	Galantide acetate 是一种特殊的甘丙肽受体 (galanin receptor) 拮抗剂，是一种由甘丙肽和 P 物质片段组成的肽段，在大鼠下丘脑可识别两类甘丙肽结合位点 (KD 分别小于 0.1 nM 和 ~6 nM)。Galantide 剂量依赖性 (IC50=1.0 nM) 拮抗甘丙肽介导的葡萄糖诱导的小鼠胰岛胰岛素分泌抑制。Galantide acetate 似乎与单一的 SP 受体群结合 (KD~40 nM)。
TP1696L	CGGRGD acetate(1260223-44-6 free base)	Others	Others
	CGGRGD acetate(1260223-44-6 free base) 是一种以半胱氨酸为 n 端的 RGD 衍生物。 CGGRGD 采用固相多肽合成技术合成，在PCL 纤维表面添加氨基2-氰基苯并噻唑(2-cyanobenzothiazole)(2-cyanobenzothiazole (CBT))进行氨化。
TP2312	MOTS-c(Human) Acetate（1627580-64-6 free）	Others; AMPK	Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling
	MOTS-c(Human) Acetate（1627580-64-6 free）是一种线粒体衍生肽。它诱导 AMP 类似物 AICAR 的积累，增加 AMPK 的激活和其下游 GLUT4 的表达。它可诱导葡萄糖摄取并提高胰岛素敏感性。它对调节肥胖、糖尿病、运动和长寿有重要意义。
TP1930L1	Spexin acetate(1370290-58-6 free base)	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	Spexin acetate(1370290-58-6 free base) 是一种有效的甘丙肽受体 2/3 (GAL2/GAL3) 激动剂（EC50 值分别为 45.7 和 112.2 nM）。对甘丙肽受体 1 没有显着的活性。抑制脂肪细胞对长链脂肪酸的摄取并减少饮食诱导的肥胖小鼠和大鼠的食物消耗。减少金鱼的 LH 分泌。在体内表现出抗焦虑作用。
T38852	TRAP-6 amide
	TRAP-6 amide is a PAR-1 thrombin receptor agonist peptide.
T38887	TRAP-6 amide TFA
	TRAP-6 amide TFA is a PAR-1 thrombin receptor agonist peptide.
T76650	PAR-2 (1-6) (human)
	PAR-2 (1-6) (human) (SLIGKV) 是 PAR-2的多肽激动剂。
T41012	Mad1 (6-21) Mad1 (6-21)
	Mad1 (6-21) is a peptide fragment derived from the Mad1 protein, specifically encompassing residues 6 to 21. This fragment exhibits binding affinity towards the mammalian Sin3A PAH2 domain, with a Kd value of approximately 29 nM.
T36289	Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA
	Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a peptide that acts as an agonist for the proteinase-activated receptor (PAR-3)[1].
T13560	AT-1002	Others	Others
	AT-1002 is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide.
TP1283	VIP(6-28)(human, rat, porcine, bovine)
	VIP(6-28)(human, rat, porcine, bovine) is a potent antagonist that effectively counteracts the effects of exogenous vasoactive intestinal peptide (VIP) on cyclic adenosine monophosphate (cAMP) signaling.
TP1603	β-Casomorphin (1-6), bovine
	β-Casomorphin (1-6), bovine is a opioid-like bioactive peptide of β-Casomorphin.
T13560L	AT-1002 TFA (835872-35-0 free base) AT-1002 TFA	Others	Others
	AT-1002 TFA is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide.
T73811	AT-1002 TFA
	AT-1002 TFA 是一种 6 聚体合成肽，是一种紧密连接 (junction) 的调节剂和吸收增强剂。
T81613	Oligopeptide-6
	Oligopeptide-6作为一种生物活性肽，具备显著的保湿功能，并广泛作为化妆品配料使用。
TP2047	CRF(6-33)(human) CRF (6-33)
	CRF(6-33)(human) is a Corticotropin-releasing factor binding protein (CRFBP) inhibitor peptide; displaces CRF from CRFBP. Suppresses body weight gain and increases motor activity in obese rats in vivo.
TP1747	Bradykinin (1-6)
	Bradykinin (1-6) is an amino-truncated Bradykinin peptide. Bradykinin (1-6) is a stable metabolite of Bradykinin, cleaved by carboxypeptidase Y (CPY).Bradykinin (1-6) is a fragment of bradykinin. Bradykinin activates pain receptors. It induces smooth musc
T25481	H 77 H77,H-77
	H 77 is a new effective renin inhibitor. H 77 is angiotensinogen (6-13)-octapeptide in which the peptide bond -CO-NH- at the Leu(9)-Leu(11) linkage is replaced by a -CH2-NH- bond.
TD0062	6-CR110 [6-Carboxyrhodamine 110] Single isomer 6-羧基罗丹明110（单一化合物）
	6-CR110 [6-Carboxyrhodamine 110] Single isomer is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM.
T81565	Palmitoyl hexapeptide-14 Palmitoyl hexapeptide-6
	Palmitoyl hexapeptide-14（亦称为Palmitoyl hexapeptide-6）是一种生物活性肽，因其抗皱功能而常作为化妆品成分。
TP1455	Cardiotoxin Analog (CTX) IV (6-12) Cardiotoxin Analog (CTX) IV 6-12
	Cardiotoxin Analog (CTX) IV (6-12) is a part peptide of Cardiotoxin Analog (CTX) IV. Cardiotoxin analogues IV isolated from the venom of Taiwan Cobra.
TP1284	LL-37, Human TFA (154947-66-7 free base) LL-37, Human TFA
	Human LL-37 is a 37 amino acid cationic (6+) peptide and has been widely studied. LL-37 penetrates the bacterial membrane and forms pores in the membrane.
TP2291	signal transducer and activator of transcription 6 fragment	Others	Others
	The signal transducer and activator of transcription 6 fragments is a peptide with the sequence H2N-Ser-Tyr-Trp-Ser-Asp-Arg-Leu-Ile-Ile-OH, MW= 1152.3.
TD0063	5(6)-CR110, SE [5-(and 6)-Carboxyrhodamine 110, succinimidyl ester] Mixed isomers 5(6)-羧基罗丹明110琥珀酰亚胺酯（混合物）
	5(6)-CR110, SE [5-(and 6)-Carboxyrhodamine 110, succinimidyl ester] Mixed isomers is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM.
T26936	C188 Cpd188,STAT3-IN-C188,Cpd-188,C 188,C-188
	C188 is a cell-permeable naphthol compound and a STAT3 inhibitor. C188 inhibits IL-6-stimulated STAT3 Tyr705 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket, while exhibiting little effect agai
TD0065	6-CR110, SE [6-Carboxyrhodamine 110, succinimidyl ester]Single isomer 6-羧基罗丹明110琥珀酰亚胺酯（单一化合物）
	6-CR110, SE [6-Carboxyrhodamine 110, succinimidyl ester]Single isomer is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM.
TD0060	5(6)-CR110 [5-(and 6)-Carboxyrhodamine 110] Mixed isomers 5(6)-羧基罗丹明110（混合物）
	5(6)-CR110 [5-(and 6)-Carboxyrhodamine 110] Mixed isomers is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM.
T35867	TRAP-6 Peptide (trifluoroacetate salt)
	TRAP-6 peptide is a hexapeptide corresponding to residues 42-47 of protease-activated receptor 1 (PAR1). It acts as an agonist of PAR1, inducing platelet aggregation in human platelet-rich plasma ex vivo (EC50 = 0.8 μM). TRAP-6 (0.3 and 0.6 mg/kg) has a triphasic effect on mean arterial blood pressure (MAP) in anesthetized rats with a short decrease, an increase, and then a longer decrease in MAP following intravenous administration.
T78434	Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) TFA
	Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) TFA 为基于荧光共振能量转移的多肽底物，通过裂解引起的荧光强度变化来确定其活性。
T74033	6-Me-ATP
	6-Me-ATP（N6-Methyl-ATP）为ATP的N6修饰衍生物。该化合物与GSK3β结合亲和力显著，能有效作为GSK3β催化底物肽磷酸化的磷酸基团供体。
T80266	GB-6	Bombesin Receptor	GPCR/G Protein
	GB-6是一种短线性肽，专门针对胃泌素释放肽受体（GRPR）。该受体在胰腺癌细胞中高表达。由于GB-6具有肿瘤选择性和肿瘤特异性积累的特点，其结合近红外（NIR）荧光染料或99mTc标记后可作为提供高对比度的成像探针。此外，GB-6在体内具有良好稳定性，并在SW1990皮下异种移植模型中显示出5.2和6.3的高肿瘤/胰腺及肿瘤/肠道荧光信号比。因此，GB-6能迅速定位肿瘤并准确描绘其边界，展示出其在临床应用中的巨大潜力。

化合物

Cat.No: T26629

Synonym: A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide

Target: PAI-1

Interleukin (IL)-6 Receptor

Cat.No: TP1422

Target: Others

TRAP-6 amide acetate

Cat.No: T38852L

Target: Protease-activated Receptor

Angiotensin I/II (1-6)

Cat.No: TP1579

Synonym: Angiotensin I/II 1-6

Target: RAAS, Others

α2β1 Integrin Ligand Peptide acetate

Cat.No: TP1484L

Synonym: α2β1 Integrin Ligand Peptide acetate (134580-64-6)

Target: Integrin

PKA inhibitor fragment (6-22) amide Acetate

Cat.No: T21674L

Synonym: PKA inhibitor fragment (6-22) amide Acetate(121932-06-7 Free base)

Target: PKA

Cat.No: T9280

Synonym: (S)-Di-tert-butyl 2-(3-((S)-6-amino-1-(tert-butoxy)-1-oxohexan-2-yl)ureido)pentanedioate

Target: Others

CRF (6-33) acetate(120066-38-8 free base)

Cat.No: TP2047L

Target: CRFR

Cardiotoxin Analog (CTX) IV (6-12) TFA

Cat.No: TP1289

Synonym: Cardiotoxin Analog (CTX) IV (6-12) (TFA)(115722-23-1,FREE)

Target: Others

c-Myc Peptide Trifluoroacetate

Cat.No: TP1315

Target: Others

β-amyloid 1-11 acetate(190436-05-6 free base)

Cat.No: TP1866L

Target: Beta Amyloid

Galnon TFA(475115-35-6(free base))

Cat.No: T8559

Target: Neuropeptide Y Receptor

Melanin Concentrating Hormone, salmon acetate

Cat.No: TP1104L

Synonym: MCH (salmon),Melanin Concentrating Hormone, salmon acetate(87218-84-6 free base)

Target: Others, Melanin-concentrating Hormone Receptor (MCHR)

Myelin Basic Protein (87-99) Acetate

Cat.No: T21618L

Synonym: Myelin Basic Protein (87-99) Acetate (118506-26-6 Free base)

Target: Others

Arg-Gly-Glu-Ser acetate(93674-97-6 free base)

Cat.No: TP1458L

Target: Others

pep2-EVKI acetate(1315378-67-6 free base)

Cat.No: TP1943L1

Target: GluR

Allatostatin IV TFA(123338-13-6 free base)

Cat.No: TP1605L1

Target: Others

Jagged-1 (188-204) TFA(219127-21-6 free base)

Cat.No: TP1293

Synonym: Jagged-1 (188-204) TFA

Target: Gamma-secretase

NLS PKKKRKV acetate(95088-49-6 free base)

Cat.No: TP1606L

Target: Others

Galantide acetate

Cat.No: T15368L

Synonym: Galantide acetate(138579-66-5 Free base)

Target: Neuropeptide Y Receptor

CGGRGD acetate(1260223-44-6 free base)

Cat.No: TP1696L

Target: Others

MOTS-c(Human) Acetate（1627580-64-6 free）

Cat.No: TP2312

Target: Others, AMPK

Spexin acetate(1370290-58-6 free base)

Cat.No: TP1930L1

Target: Neuropeptide Y Receptor

Cat.No: T38852

TRAP-6 amide TFA

Cat.No: T38887

PAR-2 (1-6) (human)

Cat.No: T76650

Cat.No: T41012

Synonym: Mad1 (6-21)

Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA

Cat.No: T36289

Cat.No: T13560

Target: Others

VIP(6-28)(human, rat, porcine, bovine)

Cat.No: TP1283

β-Casomorphin (1-6), bovine

Cat.No: TP1603

AT-1002 TFA (835872-35-0 free base)

Cat.No: T13560L

Synonym: AT-1002 TFA

Target: Others

Cat.No: T73811

Cat.No: T81613

CRF(6-33)(human)

Cat.No: TP2047

Synonym: CRF (6-33)

Bradykinin (1-6)

Cat.No: TP1747

Cat.No: T25481

Synonym: H77,H-77

6-CR110 [6-Carboxyrhodamine 110] *Single isomer*

Cat.No: TD0062

Synonym: 6-羧基罗丹明110（单一化合物）

Palmitoyl hexapeptide-14

Cat.No: T81565

Synonym: Palmitoyl hexapeptide-6

Cardiotoxin Analog (CTX) IV (6-12)

Cat.No: TP1455

Synonym: Cardiotoxin Analog (CTX) IV 6-12

LL-37, Human TFA (154947-66-7 free base)

Cat.No: TP1284

Synonym: LL-37, Human TFA

signal transducer and activator of transcription 6 fragment

Cat.No: TP2291

Target: Others

5(6)-CR110, SE [5-(and 6)-Carboxyrhodamine 110, succinimidyl ester] *Mixed isomers*

Cat.No: TD0063

Synonym: 5(6)-羧基罗丹明110琥珀酰亚胺酯（混合物）

Cat.No: T26936

Synonym: Cpd188,STAT3-IN-C188,Cpd-188,C 188,C-188

6-CR110, SE [6-Carboxyrhodamine 110, succinimidyl ester]*Single isomer*

Cat.No: TD0065

Synonym: 6-羧基罗丹明110琥珀酰亚胺酯（单一化合物）

5(6)-CR110 [5-(and 6)-Carboxyrhodamine 110] *Mixed isomers*

Cat.No: TD0060

Synonym: 5(6)-羧基罗丹明110（混合物）

TRAP-6 Peptide (trifluoroacetate salt)

Cat.No: T35867

Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) TFA

Cat.No: T78434

Cat.No: T74033

Cat.No: T80266

Target: Bombesin Receptor

Cat. No.	Product Name	Target	Signaling Pathways
T5145	Oxytocin acetate Oxytocic hormone acetate,α-Hypophamine acetate,Oxytocin acetate (50-56-6 free base),醋酸催产素	Oxytocin Receptor	Endocrinology/Hormones; GPCR/G Protein
	Oxytocin acetate (α-Hypophamine acetate) 是哺乳动物的神经垂体激素，是多效的下丘脑肽，是催产素受体的配体，有助于分娩、哺乳和亲社会行为。它可作为一种压力应对分子，具有抗炎、抗氧化剂和保护作用。
T80349	Maximin H4
	Maximin H4是一种来自中华红腹蟾蜍(Bombina maxima)皮肤分泌物的抗菌肽，具有针对Escherichia coli ATCC25922、Staphylococcus aureus ATCC2592、Bacillus pyocyaneus CMCCB1010和Candida albicans ATCC2002的抗菌活性。其最小抑菌浓度(MIC)值依次为12、6、12、6 μg/ml。

天然产物

Oxytocin acetate

Cat.No: T5145

Synonym: Oxytocic hormone acetate,α-Hypophamine acetate,Oxytocin acetate (50-56-6 free base),醋酸催产素

Target: Oxytocin Receptor

Cat.No: T80349

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