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Search Results for " 松二糖 "

1

抑制剂 & 化合物

25

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T83807	Rp-Adenosine-5'-O-(1-thiotriphosphate) sodium Rp-ATP-α-S
	Rp-Adenosine-5'-O-(1-thiotriphosphate)（Rp-ATP-α-S）是一种含硫核苷酸衍生物ATP-α-S的异构体，同时也是嘌呤P2Y1受体的激动剂。在表达人类P2Y1受体的HEK293细胞中，Rp-ATP-α-S能增加钙的动员（EC50 = 75 nM）。该化合物与洗涤的人类孤立血小板结合（Ki = 156 nM），抑制由ADP引发的人类富血小板血浆（PRP）的聚集（pA2 = 4.74），并且能够抑制前列腺素E1（PGE1）在人类孤立PRP中引发的cAMP产生（pA2 = 5.26）。同时，Rp-ATP-α-S还能引起用氨基甲酰胆碱预先缩紧的豚鼠结肠条带的松弛（EC50 = 56 nM）。此外，Rp-ATP-α-S已经被用于合成被细菌核糖开关识别的环状二核苷酸。

化合物

Rp-Adenosine-5'-O-(1-thiotriphosphate) sodium

Cat.No: T83807

Synonym: Rp-ATP-α-S

Cat. No.	Product Name	Target	Signaling Pathways
T5583	Turanose 松二糖,D-(+)-Turanose	Endogenous Metabolite	Metabolism
	Turanose (D-(+)-Turanose) 是天然存在于蜂蜜中的蔗糖异构体。它具有抗炎和调节脂肪形成的活性。它具有肥胖症和相关慢性病的研究潜力。
T6S0535	Pinoresinol diglucoside Pinoresinol Diglucopyranoside,松脂醇二葡萄糖苷	Glucosidase	Metabolism
	Pinoresinol diglucoside (Pinoresinol Diglucopyranoside) 是一种分离自杜仲和其他植物物种中的主要木脂素，具有多种药理活性。
TN3077	5,5'-Dimethoxylariciresinol 4-O-glucoside 5,5'-二甲氧基落叶松脂素4-O-葡萄糖苷	Others	Others
	5,5'-Dimethoxylariciresinol-4'-O-beta-D-glucoside is shown to effectively enhance chemosensitivity of resistant cells, which makes it may be a suitable candidate for potential multidrug resistance (MDR)-reversing agents.
TN1915	Matairesinol 4′-O-β-D-glucopyranoside Matairesinol 4'-O-beta-gentiobioside,罗汉松树脂酚-4'-O-Β-龙胆二糖苷,(3R-反式)-3-[[4-[(6-O-BETA-D-吡喃葡萄糖基-BETA-D-吡喃葡萄糖基)氧基]-3-甲氧基苯基]甲基]二氢-4-[(4-羟基-3-甲氧基苯基)甲基]-2(3H)-呋喃酮	Others	Others
	Matairesinol 4′-O-β-D-glucopyranoside 对 HeLa 细胞具有细胞毒活性(IC50:47.1 μM)。
TN2244	Sulfuretin 硫黄菊素	NF-κB; Autophagy	Autophagy; NF-κB
	Sulfuretin 是竞争性单酚酶和二酚酶活性抑制剂，IC50=13.64 μM。它通过抑制NF-κB 通路来抑制炎症反应。它可用于过敏性气道炎症的研究。它减少氧化应激、血小板聚集和诱变。
TJS0328	Nordalbergin 6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One,6,7-二羟基-4苯基香豆素	Others	Others
	Nordalbergin 是一种香豆素，分离自Dalbergia sissoo 的木皮中。它能够显著性的诱导 HL-60 细胞的分化。
T6S0722	Isoorientin Homoorientin,Luteolin-6-C-glucoside,异荭草苷;异荭草素,异荭草素	Antioxidant; COX	Immunology/Inflammation; Neuroscience; oxidation-reduction
	Isoorientin (Homoorientin) 是一种 COX-2抑制剂，IC50值为 39 μM，具有抗氧化活性。
TN2027	Oxysanguinarine 8-Oxosanguinarine,氧化血根碱,Hydroxysanguinarine	Parasite	Microbiology/Virology
	Oxysanguinarine (Hydroxysanguinarine) 是一种来自Meconopsis simplicifolia 的小檗生物碱，具有抗疟和抗血小板聚集活性，对登革热病毒具有潜在的抑制作用。
T21205	Ponasterone A 坡那甾酮A,AI3-44686	Others	Others
	Ponasterone A (AI3-44686) 是一种蜕皮激素，能够高度亲和蜕皮激素受体。它能够使报告基因能够快速打开和关闭，是细胞和转基因动物中基因表达的有效调节剂。
T4762	L-Pipecolic acid L-哌啶酸,L-Homoproline,H-HoPro-OH	Endogenous Metabolite	Metabolism
	L-Pipecolic acid (L-Homoproline) 是赖氨酸的分解产物，它能在患有常染色体遗传性疾病的婴儿体液中积累，比如新生儿肾上腺机能障碍， Zellweger 综合征等。
TN2006	Odoriflavene	Others	Others
	Odoriflavene has antioxidant activity, and it also shows inhibition effects on the decrease of glutathione level of rat lens induced by UV irradiation. Odoriflavene shows cytotoxic activity against a SH-SY5Y cell line in vitro.
TN4296	Isohemiphloin 异半皮桉苷	Others	Others
	Isohemiphloin 是一种从 Abrus precatorius Linn 中分离出来的黄酮类化合物。
TN1462	Cajanin 2',4',5-三羟基-7-甲氧基异黄酮,木豆异黄酮	ERK; MEK; Akt	Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
	Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol efflux and RCT, it can significantly improve basal glucose uptake in HepG2 cells, its improving effect is concentration dependent, it exhibits effects stronger than that of rosiglitazone, which has been used as an antidiabetic drug.
TN2180	Sappanchalcone 苏木查耳酮	IL Receptor; BCL; TNF	Apoptosis; Immunology/Inflammation
	Sappanchalcone shows xanthine oxidase inhibitory activity, is a xanthine oxidase inhibitor.
TN2469	(1R)-α-Pinene (+)-alpha-Pinene,(+)-α-蒎烯	Others	Others
	(1R)-α-Pinene 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2469，CAS号为 7785-70-8。
TN3330	9-Oxonerolidol	Others	Others
	9-Oxonerolidol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3330，CAS号为 58865-88-6。
TN5798	(R)-4-Methoxydalbergione (+)-4-Methoxydalbergione,(R)-4-甲氧基黄檀醌
	(R)-4-Methoxydalbergione 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5798，CAS号为 4646-86-0。
TN5906	2,3-Dimethoxyxanthone
	2,3-Dimethoxyxanthone 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5906，CAS号为 42833-49-8。
TN5726	2,5,2'-Trihydroxy-4-methoxybenzophenone
	2,5,2'-Trihydroxy-4-methoxybenzophenone 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5726，CAS号为 202463-52-3。
TN1653	Fustin	ERK; Beta Amyloid; AChR	MAPK; Neuroscience
	Fustin 是植物漆树 (Rhus verniciflua Stokes) 的植物性黄烷醇成分。 Fustin 对 6-羟基多巴胺诱导的神经元细胞死亡具有保护作用。
TN5227	(+/-)-Vestitol	NOS; CXCR; Antifection	Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology
	Vestitol has antioxidation, anti-inflammatory and antimicrobial activities, it can strongly act in a low dose and concentration and have a promising potential to be applied in the pharmaceutical and food industries. Vestitol inhibits neutrophils migration
TN5883	4'-O-Methylcoumestrol 4'-O-甲基香豆雌酚,9-O-Methylcoumestrol
	4'-O-Methylcoumestrol is a natural product from Glycyrrhiza pallidiflora Maxim.
T25246	Chrysanthemic acid NSC 11779,NSC11779,NSC-11779
	Chrysanthemic acid is used as an insecticide.
TN5074	Suavioside A	Others	Others
	Suavioside A tastes sweet, it could be used as a sweetener.
TN1890	Lupeol acetate	Others; TNF; NOS	Apoptosis; Immunology/Inflammation; Others
	Lupeol acetate possesses antinociceptive, antifertility, and anti-inflammatory properties, the effect probably involves the opioid system, as indicated by the complete blockade of the opioid antagonist naloxone.

天然产物

Cat.No: T5583

Synonym: 松二糖,D-(+)-Turanose

Target: Endogenous Metabolite

Pinoresinol diglucoside

Cat.No: T6S0535

Synonym: Pinoresinol Diglucopyranoside,松脂醇二葡萄糖苷

Target: Glucosidase

5,5'-Dimethoxylariciresinol 4-O-glucoside

Cat.No: TN3077

Synonym: 5,5'-二甲氧基落叶松脂素4-O-葡萄糖苷

Target: Others

Matairesinol 4′-O-β-D-glucopyranoside

Cat.No: TN1915

Synonym: Matairesinol 4'-O-beta-gentiobioside,罗汉松树脂酚-4'-O-Β-龙胆二糖苷,(3R-反式)-3-[[4-[(6-O-BETA-D-吡喃葡萄糖基-BETA-D-吡喃葡萄糖基)氧基]-3-甲氧基苯基]甲基]二氢-4-[(4-羟基-3-甲氧基苯基)甲基]-2(3H)-呋喃酮

Target: Others

Cat.No: TN2244

Synonym: 硫黄菊素

Target: NF-κB, Autophagy

Cat.No: TJS0328

Synonym: 6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One,6,7-二羟基-4苯基香豆素

Target: Others

Cat.No: T6S0722

Synonym: Homoorientin,Luteolin-6-C-glucoside,异荭草苷;异荭草素,异荭草素

Target: Antioxidant, COX

Oxysanguinarine

Cat.No: TN2027

Synonym: 8-Oxosanguinarine,氧化血根碱,Hydroxysanguinarine

Target: Parasite

Cat.No: T21205

Synonym: 坡那甾酮A,AI3-44686

Target: Others

L-Pipecolic acid

Cat.No: T4762

Synonym: L-哌啶酸,L-Homoproline,H-HoPro-OH

Target: Endogenous Metabolite

Cat.No: TN2006

Target: Others

Cat.No: TN4296

Synonym: 异半皮桉苷

Target: Others

Cat.No: TN1462

Synonym: 2',4',5-三羟基-7-甲氧基异黄酮,木豆异黄酮

Target: ERK, MEK, Akt

Cat.No: TN2180

Synonym: 苏木查耳酮

Target: IL Receptor, BCL, TNF

Cat.No: TN2469

Synonym: (+)-alpha-Pinene,(+)-α-蒎烯

Target: Others

Cat.No: TN3330

Target: Others

(R)-4-Methoxydalbergione

Cat.No: TN5798

Synonym: (+)-4-Methoxydalbergione,(R)-4-甲氧基黄檀醌

2,3-Dimethoxyxanthone

Cat.No: TN5906

2,5,2'-Trihydroxy-4-methoxybenzophenone

Cat.No: TN5726

Cat.No: TN1653

Target: ERK, Beta Amyloid, AChR

Cat.No: TN5227

Target: NOS, CXCR, Antifection

4'-O-Methylcoumestrol

Cat.No: TN5883

Synonym: 4'-O-甲基香豆雌酚,9-O-Methylcoumestrol

Chrysanthemic acid

Cat.No: T25246

Synonym: NSC 11779,NSC11779,NSC-11779

Cat.No: TN5074

Target: Others

Cat.No: TN1890

Target: Others, TNF, NOS

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