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19

抑制剂 & 化合物

28

天然产物

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Cat. No. Product Name Target Signaling Pathways
T0940 Acesulfame Potassium

Others Others
Acesulfame potassium 是一种人造甜味剂,长期使用会影响认知功能,可能改变小鼠的神经代谢功能。
T33639 Neotame

NC 00723,HSDB 7965,NC-00723,NC00723,纽甜

Others Others
Neotame (HSDB 7965) 是阿斯巴甜的衍生物,是低热量、高效的人造甜味剂,非营养性甜味剂和增味剂,其甜度是糖的 7000-13,000 倍,可用于多种食品。
T0697 Aspartame

阿斯巴甜,SC-18862

Others; Taste receptor Metabolism; Others
Aspartame (SC-18862) 是一种二肽的甲酯,由苯丙氨酸 (50%),天门冬氨酸 (40%) 和甲醇 (10%) 组成。它可用作合成的非营养性甜味剂。
T0941 Cyclamic acid

Cyclamate,NSC 220327,Cyclohexylsulfamic acid,环己基氨基磺酸,环拉酸

Others Others
Cyclamic acid (NSC-220327) 是食品和药品中应用最广泛的一种人造甜味剂。
T0889 Saccharin

O-Sulfobenzimide,O-Benzoic sulfimide,Saccharimide,Benzoic sulfimide,糖精

Others; Antibacterial Microbiology/Virology; Others
Saccharin (O-Sulfobenzimide) 是一种口服有效的人造甜味剂,具有抑菌和微生物调节特性。
T0585L Isomaltitol

Isomalt,Palatinit

Isomaltitol is sugar alcohol. Isomaltitol is commonly used as a sweetener in food products.
T34770 Tagatose

Tagatose is a sweetener based on its properties as a monosaccharide, specifically a hexose.
T40739 L-Mannitol

L-mannitol is a compound can be used for the compound sweetener synthesis.
T31707 Ethyl aspartylphenylalaninate

Ethyl aspartylphenylalaninate is an artificial non-saccharide sweetener used as a sugar substitute.
T33610 NC-174

CPDpmGA,CP Dpm GA,CP-Dpm-GA,CP-DpmGA,CPDpm-GA

NC-174 is a trisubstituted guanidine high potency synthetic sweetener.
T30172 Aspartame acesulfame

乙酰舒泛-阿司帕坦盐,Aspartame acesulfame salt,Acesulfame mixture with aspartame

Aspartame acesulfame, as an artificial sweetener, is 350 times sweeter than sucrose.
T20165 Alitame anhydrous

CP54802,CP-54802,CP 54802

Alitame anhydrous is a non-nutritive sweetener. It is 2000 times sweeter than sucrose.
T25004 Advantame anhydrous

Advantame

Advantame anhydrous is a non-caloric sweetener, synthesized from isovanillin and aspartame. The U.S. Food and Drug Administration has approved Advantame for general use in foods and beverages except for meat and poultry as a food additive.
T29866 Alitame

HSDB 7825,CP-54,802,CP 54802

Alitame is a non-nutritive sweetener that is 2000 times sweeter than sucrose. It is formed from aspartic acid, alanine & an amide.
T19977 Saccharin sodium

CCRIS 706,Saccharin, sodium

Saccharin sodium is a type of artificial or nonnutritive sweetener. Saccharin sodium is used in the production of various foods and pharmaceutical products.
T30429 beta-Alitame

beta-Alitame is a non-nutritive sweetener that is 2000 times sweeter than sucrose. It is formed from aspartic acid, alanine & an amide.
T83179 Ac-Phe-Lys-OH

Ac-Phe-Lys-OH是一种人工合成的氨基酸肽类甜味剂,具有阿斯巴甜类似的甜度。
T83161 Advantame

Advantame为阿斯巴甜衍生物,属于无热量合成甜味剂,广泛应用于食品添加剂领域。
T72909 D-(+)-Sorbose

D-(+)-Sorbose,一种 D-Sorbose 的活性对映异构体,可抑制双糖酶活性并对大鼠餐后血糖和胰岛素水平有抑制作用。D-Sorbose 作为甜味剂有助于预防相关疾病,如 2 型糖尿病。

化合物

Acesulfame Potassium
Cat.No: T0940
Synonym:
Target: Others
Neotame
Cat.No: T33639
Synonym: NC 00723,HSDB 7965,NC-00723,NC00723,纽甜
Target: Others
Aspartame
Cat.No: T0697
Synonym: 阿斯巴甜,SC-18862
Target: Others, Taste receptor
Cyclamic acid
Cat.No: T0941
Synonym: Cyclamate,NSC 220327,Cyclohexylsulfamic acid,环己基氨基磺酸,环拉酸
Target: Others
Saccharin
Cat.No: T0889
Synonym: O-Sulfobenzimide,O-Benzoic sulfimide,Saccharimide,Benzoic sulfimide,糖精
Target: Others, Antibacterial
Isomaltitol
Cat.No: T0585L
Synonym: Isomalt,Palatinit
Target:
Tagatose
Cat.No: T34770
Synonym:
Target:
L-Mannitol
Cat.No: T40739
Synonym:
Target:
Ethyl aspartylphenylalaninate
Cat.No: T31707
Synonym:
Target:
NC-174
Cat.No: T33610
Synonym: CPDpmGA,CP Dpm GA,CP-Dpm-GA,CP-DpmGA,CPDpm-GA
Target:
Aspartame acesulfame
Cat.No: T30172
Synonym: 乙酰舒泛-阿司帕坦盐,Aspartame acesulfame salt,Acesulfame mixture with aspartame
Target:
Alitame anhydrous
Cat.No: T20165
Synonym: CP54802,CP-54802,CP 54802
Target:
Advantame anhydrous
Cat.No: T25004
Synonym: Advantame
Target:
Alitame
Cat.No: T29866
Synonym: HSDB 7825,CP-54,802,CP 54802
Target:
Saccharin sodium
Cat.No: T19977
Synonym: CCRIS 706,Saccharin, sodium
Target:
beta-Alitame
Cat.No: T30429
Synonym:
Target:
Ac-Phe-Lys-OH
Cat.No: T83179
Synonym:
Target:
Advantame
Cat.No: T83161
Synonym:
Target:
D-(+)-Sorbose
Cat.No: T72909
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T2911 Stevioside

甜菊苷,蛇菊苷

TLR Immunology/Inflammation
Stevioside 是一种天然甜味剂,从甜叶菊叶中提取的获得,具有抗癌作用。
T2S1840 Rebaudioside D

莱苞迪苷D,瑞鲍迪甙D

Others Others
Rebaudioside D 是一种苷类化合物,存在于甜菊叶中,可用作甜味剂。
T1399 Sucralose

Trichlorosucrose,三氯蔗糖,E955

Others; Endogenous Metabolite Metabolism; Others
Sucralose (Trichlorosucrose) 是一种无营养的人工甜味剂 (sweetener) 和代糖,它能够激活保守神经的禁食响应,从而刺激啮齿动物产生食欲。
T0332 D-Sorbitol

山梨醇,Glucitol,Sorbitol,D-Glucitol

Others; Endogenous Metabolite Metabolism; Others
D-Sorbitol (Sorbitol) 是一种六碳糖醇,能够用作糖的替代品。D-Sorbitol 能够用作稳定的赋形剂和/或等渗剂,保湿剂,增稠剂,甜味剂和膳食补充剂。
T2767 Neohesperidin Dihydrochalcone

NHDC,新橙皮苷二氢查尔酮,新橙皮苷二氢查耳酮,Neohesperidin DC,NCI-c60764

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
Neohesperidin Dihydrochalcone (Neohesperidin DC) 是一种合成的糖苷查耳酮,可用作低热量人造甜味剂,添加到各种食品和饮料中。
TCS1188 Mogroside III

Others Others
Mogroside III 是一种三萜糖苷和非糖甜味剂。 Mogroside III 被人体肠道细菌转化,释放出次生Mogroside IIA1 和苷元莫格罗。
T2S1193 Mogroside III-A1

罗汉果苷 III-A1

Others Others
Mogroside III-A1 是一种来自罗汉果 Swingle 的三萜糖苷。 Mogroside III-A1 一种无糖甜味剂。
T2S1992 Perillartine

Perilla sugar,Peryllartine,紫苏葶,DL-Perillartine

Others; Endogenous Metabolite Metabolism; Others
Perillartine (DL-Perillartine) 是甜味剂,能够激活味觉受体 1 型成员 2 。
T12090 Mogroside I E1

罗汉果苷 I E1

Others Others
Mogroside I E1 是三萜糖苷,是非糖类甜味剂。其中 Mogroside 的甜度比蔗糖高,具有抗氧化,抗糖尿病和抗癌特性。
TN1704 Glycyrrhetic acid 3-O-β-D-glucuronide

Glycyrrhetic acid 3-O-mono-beta-D-glucuronide,单葡萄糖醛酸甘草次酸

Others Others
Glycyrrhetic acid 3-O-β-D-glucuronide 是从甘草中分离出的甘草酸 3-O-β-D-葡萄糖醛酸,是甘草甜素的重要衍生物。它具有抗过敏活性,可作为甜味剂。
TN1597 Dulcoside A

Others Others
Dulcoside A 是从甜叶菊中分离得到的。 Dulcoside A 是一种甜味剂,具有抗氧化活性。
T2761 Naringin dihydrochalcone

Naringin DC,柚皮苷二氢查尔酮,柚皮甙二氢查尔酮

P450; NF-κB Metabolism; NF-κB
Naringin dihydrochalcone (Naringin DC) 是一种新型甜味剂,是来自柚皮苷的一种人工甜味剂。它也是一种CYP enzymes 的抑制剂。
T3S2027 Rubusoside

Others Others
Rubusoside 是天然的增溶剂及甜味剂,具有良好的抗血管新生和抗过敏药的特性。
T0589 Xylitol

木糖醇,Adonitol,Ribitol,Xylite,D-Xylitol,Adonite

Others; Endogenous Metabolite; Autophagy Autophagy; Metabolism; Others
Xylitol (Ribitol) 是一种五碳糖醇,通过还原羰基衍生自木糖。它和蔗糖一样甜,可用作防龋甜味剂。
T5792 Rebaudioside M

瑞鲍迪苷M,瑞鲍迪甙M

Others Others
Rebaudioside M 是一种天然无热量甜味剂,是戊二烯二萜苷元的糖苷,提取自 Stevia rebaudianaBertoni 中。
TN1934 Mogroside IIA1

Mogroside II-A1,罗汉果苷II A1

Others; NO Synthase Immunology/Inflammation; Others
Mogroside IIA1 (Mogroside II-A1) 是从罗汉果的果实中分离得到的。Mogroside IIA1 是一种无糖甜味剂,比蔗糖更甜。 Mogroside IIA1 具有抗氧化、抗糖尿病和抗癌活性。
TN1770 Isomogroside V

Iso-mogroside V,异罗汉果皂苷 V

Others Others
Isomogroside V (Iso-mogroside V) 是一种从罗汉果提取的甜味剂,其甜度约为 0.5% (w/v) 蔗糖的 500 倍。
TN6745 PALATINOSE

TNP-470,帕拉金糖水合物,Isomaltulose

Others Others
PALATINOSE (TNP-470) 是一种天然存在的二糖,由α-1,6-连接的葡萄糖和果糖组成。PALATINOSE 对肝脏代谢功能具有有益的影响,因此可能是蔗糖甜味剂的良好替代品。
T2978 Mogroside V

AMPK Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Mogroside V 是三萜糖苷,是非糖类甜味剂,甜度比蔗糖甜高300倍。它具有抗氧化,抗糖尿病和抗癌作用。
T4964 steviolbioside

CCRIS-6025,菊双糖甙,甜菊双糖苷

Others Others
Steviolbioside (CCRIS-6025) 是一种存在于甜菊叶中的罕见甜味剂。它对几种人类癌细胞有抑制作用,对乳腺癌具有潜在的研究价值。
T3332 Isosteviol

异甜菊醇,(-)-Isosteviol

IL Receptor; Potassium Channel; TNF; NF-κB; Reactive Oxygen Species; COX; Topoisomerase Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB
Isosteviol ((-)-Isosteviol) 是一种常见的天然甜味剂,属于四环二萜糖苷,是甜菊糖苷通过酸催化水解产生的。它抑制 DNA 聚合酶和 DNA 拓扑异构酶,具有抗菌、抗癌和抗结核作用。
T2S1837 Steviol

甜菊醇,NSC 226902,Hydroxydehydrostevic acid

Others Others
Steviol (NSC-226902) 是一种甜菊糖甙的主要代谢物。它能降低 AQP2 的表达,并促进 AQP2 的降解,从而减缓肾囊肿的生长。
TN1056 Mogroside IIe

IL Receptor Immunology/Inflammation
Mogroside IIe 是一种天然来源的三萜糖苷,作为非糖类甜味剂,Mogroside 比蔗糖更甜。Mogroside 具有抗氧化,抗糖尿病和抗癌活性。
T4776 Glycerol

Glycerin,甘油

Endogenous Metabolite Metabolism
Glycerol 是甘油三酯(即脂肪和油)和磷脂的重要成分。它在食品工业中被广泛用作甜味剂和保湿剂以及药物制剂。
TN5074 Suavioside A

Others Others
Suavioside A tastes sweet, it could be used as a sweetener.
T39614 Mogroside VI A

Mogroside VI A is a saccharide compound, an isomer of Mogroside VI, that has been extracted from the Luo Han Guo plant. It possesses inherent sweetness properties. Mogroside VI A holds potential for application in sweetener and taste modifier studies.
T38706 Erlose

Erlose, a trisaccharide present in soybean aphid honeydew and composed of sucrose, acts as a sweetener substitute to inhibit dental caries formation by oral microorganisms, primarily Streptococcus mutans. Erlose can serve as a reference compound in high-performance liquid chromatography (HPLC) methods employed for the analysis of sugar content in various food samples.
T78494 Rebaudioside O

Rebaudioside O是从选育的S.rebaudiana Bertoni中分离出的一种甜菊糖苷,通常在S.rebaudiana Morita中发现,常作为甜味剂使用。

天然产物

Stevioside
Cat.No: T2911
Synonym: 甜菊苷,蛇菊苷
Target: TLR
Rebaudioside D
Cat.No: T2S1840
Synonym: 莱苞迪苷D,瑞鲍迪甙D
Target: Others
Sucralose
Cat.No: T1399
Synonym: Trichlorosucrose,三氯蔗糖,E955
Target: Others, Endogenous Metabolite
D-Sorbitol
Cat.No: T0332
Synonym: 山梨醇,Glucitol,Sorbitol,D-Glucitol
Target: Others, Endogenous Metabolite
Neohesperidin Dihydrochalcone
Cat.No: T2767
Synonym: NHDC,新橙皮苷二氢查尔酮,新橙皮苷二氢查耳酮,Neohesperidin DC,NCI-c60764
Target: Reactive Oxygen Species
Mogroside III
Cat.No: TCS1188
Synonym:
Target: Others
Mogroside III-A1
Cat.No: T2S1193
Synonym: 罗汉果苷 III-A1
Target: Others
Perillartine
Cat.No: T2S1992
Synonym: Perilla sugar,Peryllartine,紫苏葶,DL-Perillartine
Target: Others, Endogenous Metabolite
Mogroside I E1
Cat.No: T12090
Synonym: 罗汉果苷 I E1
Target: Others
Glycyrrhetic acid 3-O-β-D-glucuronide
Cat.No: TN1704
Synonym: Glycyrrhetic acid 3-O-mono-beta-D-glucuronide,单葡萄糖醛酸甘草次酸
Target: Others
Dulcoside A
Cat.No: TN1597
Synonym:
Target: Others
Naringin dihydrochalcone
Cat.No: T2761
Synonym: Naringin DC,柚皮苷二氢查尔酮,柚皮甙二氢查尔酮
Target: P450, NF-κB
Rubusoside
Cat.No: T3S2027
Synonym:
Target: Others
Xylitol
Cat.No: T0589
Synonym: 木糖醇,Adonitol,Ribitol,Xylite,D-Xylitol,Adonite
Target: Others, Endogenous Metabolite, Autophagy
Rebaudioside M
Cat.No: T5792
Synonym: 瑞鲍迪苷M,瑞鲍迪甙M
Target: Others
Mogroside IIA1
Cat.No: TN1934
Synonym: Mogroside II-A1,罗汉果苷II A1
Target: Others, NO Synthase
Isomogroside V
Cat.No: TN1770
Synonym: Iso-mogroside V,异罗汉果皂苷 V
Target: Others
PALATINOSE
Cat.No: TN6745
Synonym: TNP-470,帕拉金糖水合物,Isomaltulose
Target: Others
Mogroside V
Cat.No: T2978
Synonym:
Target: AMPK
steviolbioside
Cat.No: T4964
Synonym: CCRIS-6025,菊双糖甙,甜菊双糖苷
Target: Others
Isosteviol
Cat.No: T3332
Synonym: 异甜菊醇,(-)-Isosteviol
Target: IL Receptor, Potassium Channel, TNF, NF-κB, Reactive Oxygen Species, COX, Topoisomerase
Steviol
Cat.No: T2S1837
Synonym: 甜菊醇,NSC 226902,Hydroxydehydrostevic acid
Target: Others
Mogroside IIe
Cat.No: TN1056
Synonym:
Target: IL Receptor
Glycerol
Cat.No: T4776
Synonym: Glycerin,甘油
Target: Endogenous Metabolite
Suavioside A
Cat.No: TN5074
Synonym:
Target: Others
Mogroside VI A
Cat.No: T39614
Synonym:
Target:
Erlose
Cat.No: T38706
Synonym:
Target:
Rebaudioside O
Cat.No: T78494
Synonym:
Target:
TargetMol Loading
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