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Search Results for " selenocysteine "

6

抑制剂 & 化合物

1

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T9427	Selenocysteine	Others	Others
	Selenocysteine 被认为是核糖体介导的蛋白质合成中的第 21 个氨基酸，其特异性掺入由 UGA 密码子指导。
T8375	ML-210 CID 49766530	Ferroptosis; GPX; Glutathione Peroxidase; Ras	Apoptosis; GPCR/G Protein; MAPK; Metabolism; oxidation-reduction
	ML-210 (CID 49766530) 是一种共价的选择性谷胱甘肽过氧化物酶 4 (GPX4) 抑制剂，EC50为 30 nM。它与 GPX4 硒代半胱氨酸残基结合，具有抗癌活性。
T78587	Se-Methylselenocysteine hydrochloride Methylselenocysteine hydrochloride,Se-Methylseleno-L-cysteine hydrochloride	Beta-Secretase	Neuroscience
	Se-Methylselenocysteine hydrochloride 是一种甲基硒的前体，展现出显著的癌症化学预防和抗氧化活性。该化合物拥有优良的口服生物活性，并能有效诱导细胞凋亡(apoptosis)。
T39664	Ethaselen BBSKE
	Ethaselen (BBSKE), a selective thioredoxin reductase (TrxR) inhibitor, is orally active with IC50s of 0.5 and 0.35 μM for wild-type human TrxR1 and rat TrxR1, respectively. Ethaselen specifically binds to the unique selenocysteine-cysteine redox pair located in the C-terminal active site of mammalian TrxR1. As an organoselenium compound, it demonstrates potent antitumor activity against non-small cell lung cancer (NSCLC) by targeting TrxR.
T34604	Selenodicysteine
	Selenodicysteine is the 21st proteinogenic amino acid. Selenocysteine exists naturally in all three domains of life, but not in every lineage.
T39048	Sel-green
	Sel-green is a selective selenol fluorescent probe used for quantifying the selenocysteine (Sec) content in the selenoenzyme thioredoxin reductase, as well as imaging endogenous Sec in live HepG2 cells.

化合物

Selenocysteine

Cat.No: T9427

Target: Others

Cat.No: T8375

Synonym: CID 49766530

Target: Ferroptosis, GPX, Glutathione Peroxidase, Ras

Se-Methylselenocysteine hydrochloride

Cat.No: T78587

Synonym: Methylselenocysteine hydrochloride,Se-Methylseleno-L-cysteine hydrochloride

Target: Beta-Secretase

Cat.No: T39664

Synonym: BBSKE

Selenodicysteine

Cat.No: T34604

Cat.No: T39048

Cat. No.	Product Name	Target	Signaling Pathways
T7727	Se-Methylselenocysteine Se MSC,SeMCys,MSeC,L-硒甲基硒代半胱氨酸,Se-MSC,SeMSC	BCL; IAP; Caspase	Apoptosis; Proteases/Proteasome
	Se-Methylselenocysteine (Se-MSC) 是具有口服活性的甲基硒前体，具有强大的抗氧化活性和抗癌活性。Se-Methylselenocysteine 可诱导细胞凋亡。

天然产物

Se-Methylselenocysteine

Cat.No: T7727

Synonym: Se MSC,SeMCys,MSeC,L-硒甲基硒代半胱氨酸,Se-MSC,SeMSC

Target: BCL, IAP, Caspase

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