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Search Results for " psychoactive "

19

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T12492	Pivagabine CXB-722,匹伐加宾	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Pivagabine (CXB-722) 是疏水性 4-氨基丁酸的衍生物，具有神经调节活性。它可穿透大鼠的血脑屏障，拮抗足部休克对大鼠脑中 GABAA 受体功能和促肾上腺皮质激素释放因子 (CRF) 浓度的影响。
T4008	Metergoline 甲麦角林,Methergoline,Liserdol	Dopamine Receptor; 5-HT Receptor; Sodium Channel	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	Metergoline (Methergoline) 是多巴胺激动剂和血清素拮抗剂。它是 h5-HT7受体的高亲和力配体，Ki 为 16 nM。它还是可逆神经 Na+通道抑制剂，用于研究季节性情绪障碍、催乳激素调节。
T50076	(2E)-3-(3,5-dimethoxyphenyl)-1-(2-methoxyphenyl)prop-2-en-1-one	Others	Others
	(2E)-3-(3,5-dimethoxyphenyl)-1-(2-methoxyphenyl)prop-2-en-1-one 又称DMPVP，是一种新型的合成化合物，属于卡西酮类，具有精神活性。
T21428	Mianserin Lantanon,Lumin,Norval,Lerivon,Depnon	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Mianserin 是H1受体反向激动剂，是四环抗抑郁药(TeCA)治疗家族中的一种精神活性化合物，具有抗抑郁、抗焦虑、止吐、促氧、催眠和抗组胺作用，可作为去甲肾上腺素和特定的血清素联合用药能治疗抑郁症。
T50039	3-(2-aminopropyl)phenol hydrochloride	Others	Others
	3-(2-aminopropyl)phenol hydrochloride 是一种用作分子结构单元的苯乙胺类化合物。它是一种精神活性药物，是5-HT1A、5-HT1B 和5-HT2C 等几种血清素受体的部分激动剂，也是5-HT2A 受体的拮抗剂。
T7277	SB 242084 6 - 氯-2,3 - 二氢- 5 -甲基- N - [6 - [(2 - 甲基-3 - 吡啶基)氧] -3 - 吡啶基] - 1H -吲哚- 1 - 酰胺盐酸盐,SB 242084 dihydrochloride hydrate	5-HT Receptor	GPCR/G Protein; Neuroscience
	SB 242084 是5-HT2C 选择性抑制剂，pKi 值9.0，是一种精神活性药物和研究化学品。
T0322	Fipexide	Dopamine Receptor; AChR	GPCR/G Protein; Neuroscience
	Fipexide 是对氯苯乙酸衍生物，是哌嗪化学类的精神活性药物，作为促智药物，有用于老年痴呆的研究潜力。它可降低了纹状体腺苷酸环化酶的活性，通过多巴胺能神经传递对认知表现出积极的作用。
T34559	SC-53116 SC 53116 HCl,SC53116 HCl
	SC-53116 HCl can increase the production of serotonin in central nervous system tissues and is a psychoactive agent.
T39962	Valiloxibic acid XWL-008,Acidum valiloxibicum
	Valiloxibic acid is a prodrug of γ-Hydroxybutyric acid (GHB).GHB is a naturally occurring neurotransmitter and a psychoactive drug, it acts on the GHB receptor and is a weak agonist at the GABAB receptor.
T22332	Fipexide hydrochloride 盐酸非哌西特	Others	Others
	Fipexide (hydrochloride) is a kind of psychoactive drug of the piperazine class.
T13596	Carburazepam RGH 3331,Uxepam	Others	Others
	Carburazepam is a derivate of benzodiazepines. Benzodiazepines are a class of psychoactive drugs.
T32131	Iboxygaine Kimvuline
	Iboxygaine is a natural psychoactive substance to ease withdrawal and prevent cravings.
T34359	Ro 3-5940 HCl Ro 3 5940 HCl
	Ro 3-5940 HCl is a psychoactive agent, increasing in production of serotonin in central nervous system tissue.
T15701	Methyldopa hydrochloride L-(-)-α-Methyldopa hydrochloride,MK-351 hydrochloride	Others	Others
	L-(-)-α-Methyldopa hydrochloride is an alpha-adrenergic agonist psychoactive drug. It is used as a sympatholytic or antihypertensive. Methyldopa has a dual mechanism of action. It is a competitive inhibitor of the enzyme DOPA decarboxylase, which converts
T25717	L-Ibotenic acid Ibotenic acid, L-
	L-Ibotenic acid is a chemical compound and psychoactive drug which occurs naturally in Amanita muscaria and related species of mushrooms typically found in the temperate and boreal regions of the northern hemisphere. It is a conformationally-restricted an
T69275	DOV-102677
	DOV-102677 is a psychoactive drug being developed by Merck and is currently in clinical trials. It is a triple reuptake inhibitor, or serotonin-norepinephrine-dopamine reuptake inhibitor. It is the-enantiomer of DOV-216,303, and its-enantiomer is DOV-21,947.
T60368	Benzoctamine
	Benzoctamine 是一种口服有效作用精神剂，具有镇静作用。Benzoctamine 增加儿茶酚胺的周转率。Benzoctamine 增强大鼠心脏中 [3H] 去甲肾上腺素的摄取。Benzoctamine 也可加速脑内注射 [3H] 去甲肾上腺素的消失。
T73608	Muscimol hydrochloride
	Muscimol (Agarin; Agarine) hydrochloride 是一种具有精神活性的异恶唑。Muscimol hydrochloride 也是抑制性神经递质 GABA 离子型受体的选择性激动剂。Muscimol hydrochloride 可以从毒蝇伞和相关蘑菇中分离出来。总之，Muscimol 是一种有效的 GABAA 受体激动剂 (EC50=0.2 μM)，部分 GABAC 受体激动剂和无活性的 GABAB 受体激动剂。Muscimol hydrochloride 具有镇静、抗焦虑和致幻作用。
T69578	D-Ibotenic Acid
	D-Ibotenic Acid is a chemical compound and psychoactive drug which occurs naturally in Amanita muscaria and related species of mushrooms typically found in the temperate and boreal regions of the northern hemisphere. It is a conformationally-restricted analogue of the neurotransmitter glutamate, and due to its structural similarity to this neurotransmitter, acts as a non-selective glutamate receptor agonist. Because of this, ibotenic acid can be a powerful neurotoxin, and is employed as a brain-...

化合物

Cat.No: T12492

Synonym: CXB-722,匹伐加宾

Target: GABA Receptor

Cat.No: T4008

Synonym: 甲麦角林,Methergoline,Liserdol

Target: Dopamine Receptor, 5-HT Receptor, Sodium Channel

(2E)-3-(3,5-dimethoxyphenyl)-1-(2-methoxyphenyl)prop-2-en-1-one

Cat.No: T50076

Target: Others

Cat.No: T21428

Synonym: Lantanon,Lumin,Norval,Lerivon,Depnon

Target: Histamine Receptor

3-(2-aminopropyl)phenol hydrochloride

Cat.No: T50039

Target: Others

Cat.No: T7277

Synonym: 6 - 氯-2,3 - 二氢- 5 -甲基- N - [6 - [(2 - 甲基-3 - 吡啶基)氧] -3 - 吡啶基] - 1H -吲哚- 1 - 酰胺盐酸盐,SB 242084 dihydrochloride hydrate

Target: 5-HT Receptor

Cat.No: T0322

Target: Dopamine Receptor, AChR

Cat.No: T34559

Synonym: SC 53116 HCl,SC53116 HCl

Valiloxibic acid

Cat.No: T39962

Synonym: XWL-008,Acidum valiloxibicum

Fipexide hydrochloride

Cat.No: T22332

Synonym: 盐酸非哌西特

Target: Others

Cat.No: T13596

Synonym: RGH 3331,Uxepam

Target: Others

Cat.No: T32131

Synonym: Kimvuline

Cat.No: T34359

Synonym: Ro 3 5940 HCl

Methyldopa hydrochloride

Cat.No: T15701

Synonym: L-(-)-α-Methyldopa hydrochloride,MK-351 hydrochloride

Target: Others

L-Ibotenic acid

Cat.No: T25717

Synonym: Ibotenic acid, L-

Cat.No: T69275

Cat.No: T60368

Muscimol hydrochloride

Cat.No: T73608

D-Ibotenic Acid

Cat.No: T69578

Cat. No.	Product Name	Target	Signaling Pathways
T2797	Harmaline	Others	Others
	Harmaline 是一种来自harmala 生物碱和β-咔啉的荧光精神活性吲哚生物碱。它是harmine 的还原氢化形式。
T3698	alpha-Asarone α-Asarone,trans-Asarone,α-细辛脑	P450; GABA Receptor; HMG-CoA Reductase	Membrane transporter/Ion channel; Metabolism; Neuroscience
	alpha-Asarone (trans-Asarone) 是来自胡萝卜的一种天然产物，具有抗抑郁等功效。
T0505	Methyldopa L-(-)-α-Methyldopa,MK-351,甲基多巴	Dopamine Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	L-(-)-α-Methyldopa (MK-351) 是一种前药，在中枢神经系统中被代谢成 α-Methylepinephrine。它是 α-肾上腺素能激动剂，对 α2- adrenergic receptors 有选择性。
T74056	epi-Aszonalenin A
	epi-Aszonalenin A 是一种苯二氮卓类真菌代谢物，从Aspergillus novofumigatus 中分离得到。epi-Aszonalenin A 可影响精神活动。

天然产物

Cat.No: T2797

Target: Others

Cat.No: T3698

Synonym: α-Asarone,trans-Asarone,α-细辛脑

Target: P450, GABA Receptor, HMG-CoA Reductase

Cat.No: T0505

Synonym: L-(-)-α-Methyldopa,MK-351,甲基多巴

Target: Dopamine Receptor, Adrenergic Receptor

epi-Aszonalenin A

Cat.No: T74056

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