首页工具

登录

搜索结果

Search Results for " postoperative "

25

抑制剂 & 化合物

1

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T1242	Alvimopan 爱维莫潘	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Alvimopan (LY 246736) 是一种选择性和竞争性 μ 阿片受体拮抗剂，IC50值为 1.7 nM。它存在于肌间和黏膜下神经元以及人体肠道固有层的免疫细胞中，可用于术后肠梗阻的研究。
T9833	Opiranserin hydrochloride	P2X Receptor; GlyT; 5-HT Receptor	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	Opiranserin hydrochloride 是甘氨酸转运蛋白 2 型 (GlyT2) 和 5-羟色胺受体 2A (5HT2A) 的双重拮抗剂，IC50 分别为 0.86 和 1.3 μM。它显示对 rP2X3 的拮抗活性 (IC50=0.87 μM)。它正在开发为用于治疗术后疼痛的注射剂。
T1780	Parecoxib SC 69124,帕瑞昔布,Vorth-P,Valus-P	COX	Immunology/Inflammation; Neuroscience
	Parecoxib (SC 69124) 是一种有效的选择性 COX-2 抑制剂，是 Valdecoxib 的前药。
T21412	Ketorolac Toradol,Sprix,Acuvail,Macril,酮咯酸,Acular	COX	Immunology/Inflammation; Neuroscience
	Ketorolac (Acuvail) 是非甾体抗炎剂，是非选择性的COX 抑制剂，对 COX-1 和 COX-2 的IC50值分别为 20 和 120 nM。
T3126	Bethanechol chloride (±)-Bethanechol,Urecholine,Myocholine,氯贝胆碱,Carbamyl-β-methylcholine chloride	AChR	Neuroscience
	Bethanechol chloride (Carbamyl-β-methylcholine chloride) 是一种拟副交感神经剂，是毒蕈碱型受体 (mAChR) 激动剂，通过直接刺激副交感神经系统的 mAChR 发挥作用。
T16399	Opiranserin	P2X Receptor; GlyT; 5-HT Receptor	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	Opiranserin 是一种非阿片类和非 NSAID 镇痛候选药物，是 2 型甘氨酸转运蛋白 (GlyT2) 和 5-羟色胺受体 2A (5HT2A) 的双重拮抗剂，IC50分别为 0.86 和 1.3 μM。它可用于术后疼痛的研究，对 rP2X3 有拮抗作用，IC50为0.87 μM。
T1406	Amantadine hydrochloride 盐酸金刚烷胺,1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride	Dopamine Receptor; Influenza Virus	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Amantadine hydrochloride (CI-719) 是一种抗病毒药物，用于预防或对症治疗甲型流感和帕金森病。它阻断质子流通过 M2 离子通道，从而阻止病毒 RNA 释放到感染细胞的细胞质中。
T28703	SC-75416 SC75416
	SC-75416, a cyclooxygenase-2 (COX-2) inhibitor, is used potentially for the treatment of postoperative inflammation.
T68057	Doxpicomine	Others	Others
	Doxpicomine 具有镇痛活性，可用于治疗术后疼痛。
T8157	Centhaquin PMZ-2010,Centhaquine	Others	Others
	Centhaquin (Centhaquine)e 是一种具有研究出血性休克的潜力的试剂。在出血模型中，它能够减少全身血管阻力。
T6625	Ozagrel hydrochloride Ozagrel HCl,盐酸奥扎格雷,OKY-046 HCl	Thrombin; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Proteases/Proteasome
	Ozagrel hydrochloride (OKY-046 HCl) 是一种选择性血栓素 A(2) 合成酶抑制剂，用于改善术后脑血管收缩和伴随的脑缺血。它是一种抗血小板剂，可选择性抑制人血小板聚集，IC50为 53.12 μM。
T6236	Ozagrel 奥扎格雷,OKY-046,Domenan	Thrombin; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Proteases/Proteasome
	Ozagrel (Domenan) 是血栓烷 A2(TXA2) 合酶抑制剂，可抑制哮喘。它也是一种抗血小板剂，可选择性抑制人血小板聚集，IC50为 53.12 μM。
T31759	Felbinac Trometamol L141,Felbinac,L-141,L 141
	Felbinac Trometamol is an intravenous preparation used to treat severe postoperative pain.
T27079	CR-665 Acetate FE200665,CR-665,JNJ-38488502,CR665,FE-200665,JNJ38488502
	CR-665, a kappa-opioid agonist, is used potentially for the treatment of postoperative pain.
T80501	Myr-TAT-CBD3	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Myr-TAT-CBD3是CRMP2-CaV2.2交互作用的抑制剂，有效减弱角叉菜胶诱导的热超敏反应，并能逆转大鼠术后疼痛模型的热超敏反应，适用于炎症和术后疼痛研究。
T71601	CU-2010
	CU-2010 is a synthetic serine protease inhibitor with antifibrinolytic and anticoagulant properties. CU-2010 dose-dependently reduces postoperative blood loss and improves postischemic recovery after cardiac surgery in a canine model.
T71551	KAI-1678
	KAI-1678 is an inhibitor of epsilon protein kinase C (εPKC). KAI-1678 is effective in the treatment of postoperative pain following total hip or total knee replacement.
T68563	Piroxicam olamine
	Piroxicam olamine is a cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
T73233	Ciramadol WY 15705
	Ciramadol (WY 15705) 是一种有效的镇痛剂，具有麻醉激动剂和拮抗剂的特点。Ciramadol (WY 15705) 可用于术后疼痛治疗研究。
T60435	Propacetamol
	Propacetamol 是可代谢为 paracetamol 的前体药物，是一种镇痛剂，可用于术后疼痛、急性创伤和胃肠道疾病。
T1780L	Parecoxib sodium SC 69124A,SC-69124A,帕瑞昔布钠,SC69124A,Dynastat
	Parecoxib is a cyclooxygenase-2 inhibitor used for the short-term treatment of postoperative pain in adults. Parecoxib is a water-soluble and injectable prodrug of valdecoxib. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib and r
T68211	Piroxicam betadex
	Piroxicam betadex is a nonsteroidal anti-inflammatory drug. The mechanism of action of piroxicam is as a cyclooxygenase Inhibitor. It is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. It is used to reduce pain, swelling, and joint stiffness from arthritis. Reducing these symptoms helps you do more of your normal daily activities.
T22238	Alvimopan dihydrate (LY246736 dihydrate)
	Alvimopan dihydrate（ADL 8-2698 dihydrate）是一种有效的μ-阿片受体（μ-opioid receptor）可逆拮抗剂，具备口服活性，选择性强，IC50值为1.7 nM。其对μ-阿片受体的选择性（Ki=0.47 nM）远高于κ-（Ki=100 nM）和δ-阿片受体（Ki=12 nM），显示出在术后肠梗阻研究中的潜力。
T60496	Ketorolac hemicalcium
	Ketorolac (RS37619) hemicalcium 是一种非选择性的 COX 抑制剂，对 COX-1 的 IC50 为 20 nM，对 COX-2 的 IC50 为 120 nM。 Ketorolac hemicalcium 是一种非甾体类抗炎药 (NSAID)，可用作 0.5% 滴眼液，用于研究过敏性结膜炎、黄斑囊样水肿、术中瞳孔缩小和术后眼部炎症和疼痛等。 Ketorolac hemicalcium 也是一种可用于癌症研究的 DDX3 抑制剂 [1] [4]。
T71212	Lornoxicam-d4
	Lornoxicam-d4 is intended for use as an internal standard for the quantification of lornoxicam by GC- or LC-MS. Lornoxicam is a COX inhibitor and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties. It inhibits production of thromboxane B2 from arachidonic acid in HEL human erythroleukemic cells, which endogenously express COX-1, as well as inhibits LPS-induced formation of prostaglandin F1α from arachidonic acid in Mono-Mac-6 cells, which endogenously e...

化合物

Cat.No: T1242

Synonym: 爱维莫潘

Target: Opioid Receptor

Opiranserin hydrochloride

Cat.No: T9833

Target: P2X Receptor, GlyT, 5-HT Receptor

Cat.No: T1780

Synonym: SC 69124,帕瑞昔布,Vorth-P,Valus-P

Target: COX

Cat.No: T21412

Synonym: Toradol,Sprix,Acuvail,Macril,酮咯酸,Acular

Target: COX

Bethanechol chloride

Cat.No: T3126

Synonym: (±)-Bethanechol,Urecholine,Myocholine,氯贝胆碱,Carbamyl-β-methylcholine chloride

Target: AChR

Cat.No: T16399

Target: P2X Receptor, GlyT, 5-HT Receptor

Amantadine hydrochloride

Cat.No: T1406

Synonym: 盐酸金刚烷胺,1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride

Target: Dopamine Receptor, Influenza Virus

Cat.No: T28703

Synonym: SC75416

Cat.No: T68057

Target: Others

Cat.No: T8157

Synonym: PMZ-2010,Centhaquine

Target: Others

Ozagrel hydrochloride

Cat.No: T6625

Synonym: Ozagrel HCl,盐酸奥扎格雷,OKY-046 HCl

Target: Thrombin, Prostaglandin Receptor

Cat.No: T6236

Synonym: 奥扎格雷,OKY-046,Domenan

Target: Thrombin, Prostaglandin Receptor

Felbinac Trometamol

Cat.No: T31759

Synonym: L141,Felbinac,L-141,L 141

Cat.No: T27079

Synonym: FE200665,CR-665,JNJ-38488502,CR665,FE-200665,JNJ38488502

Cat.No: T80501

Target: Calcium Channel

Cat.No: T71601

Cat.No: T71551

Piroxicam olamine

Cat.No: T68563

Cat.No: T73233

Synonym: WY 15705

Cat.No: T60435

Parecoxib sodium

Cat.No: T1780L

Synonym: SC 69124A,SC-69124A,帕瑞昔布钠,SC69124A,Dynastat

Piroxicam betadex

Cat.No: T68211

Alvimopan dihydrate (LY246736 dihydrate)

Cat.No: T22238

Ketorolac hemicalcium

Cat.No: T60496

Cat.No: T71212

Cat. No.	Product Name	Target	Signaling Pathways
T7060	Amantadine 1-Aminoadamantane,1-金刚烷胺,金刚烷胺,1-Adamantanamine,1-Adamantylamine	Others	Others
	Amantadine (1-Aminoadamantane) 是抗病毒药物，也是是 NMDA 型谷氨酸受体的弱拮抗剂，能促进高多巴胺的释放，并阻断多巴胺的再摄取。

天然产物

Cat.No: T7060

Synonym: 1-Aminoadamantane,1-金刚烷胺,金刚烷胺,1-Adamantanamine,1-Adamantylamine

Target: Others

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼