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23

抑制剂 & 化合物

21

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T81424	Polysaccharidase Tremella polysaccharide
	Polysaccharidase (Tremella polysaccharide) 是一种提升免疫功能的真菌多糖。该化合物展现出治疗化疗和放疗导致的白细胞减少症的研究潜力。
TP2365L	Acetyl tetrapeptide-9 Acetate Acetyl tetrapeptide-9 Acetate(928006-50-2 Free base)	Others	Others
	Acetyl tetrapeptide-9 Acetate 在刺激基底膜多糖（lumican）和胶原蛋白 I 的合成中发挥作用。
T40626	Curdlan	Others	Others
	Curdlan 是一种多糖，由细菌产生。
T10110	3-CPs 3-Carbethoxypsoralen,3-Ethoxycarbonylpsoralen	Antibiotic	Microbiology/Virology
	3-CPs (3-Carbethoxypsoralen) 是一种博来霉素诱导的小鼠肺纤维化血清型荚膜多糖，属于补骨脂，可干扰抗体介导的细菌杀伤作用。3-CPs 可延缓博来霉素诱导的小鼠肺纤维化，可用于研究气道炎和哮喘。
T6531	Heparin sodium salt 肝素钠,Sodium heparinate,Heparin sodium	Factor Xa; Thrombin; Autophagy	Autophagy; Metabolism; Proteases/Proteasome
	Heparin sodium salt (Sodium heparinate) 是一种抗凝剂，可与抗凝血酶 III 可逆地结合，使凝血酶因子 IIa 和 Xa 的失活速度加快，显着抑制外泌体-细胞相互作用。
T38246	L-Triguluronic acid
	L-Triguluronic acid, a linear polysaccharide copolymer consisting of three L-guluronic acid (G) units, serves as a precursor for Alginate[1]. Alginate, an unbranched polyanionic polysaccharide, has applications in the development of delivery carriers for anti-fungal agents[2].
T71881	Bromophenol red
	Bromophenol red (BPR) is a chemical indicator. It has been shown to bind to lysozymes and inhibits their activity against bacterial cell walls, but not against the polysaccharide component of peptidoglycan.
T39278	L-Pentaguluronic acid
	L-Pentaguluronic acid, a linear polysaccharide copolymer, consists predominantly of four units of L-guluronic acid (G).
T75673	L-Diguluronic acid disodium
	L-Diguluronic acid disodium 是由两个 L-Guluronic acid 单元直接连接形成的直链多糖共聚物，主要应用于海藻酸的合成。作为无支链的聚阴离子多糖，它在抗真菌试剂载体的研究中也有其用途。
TP2365	Acetyl tetrapeptide-9 LS9745,N-Acetyl-gln-asp-val-his,Dermican,LS-9745,LS 9745
	Acetyl tetrapeptide-9 is important for the stimulation of basement membrane polysaccharide (lumican) and the synthesis of collagen I.
T38982	L-Tetraguluronic acid
	L-Tetraguluronic acid, a linear polysaccharide copolymer, comprises four units of L-guluronic acid (G).
T39279	L-Hexaguluronic acid
	L-Hexaguluronic acid, a linear polysaccharide copolymer, consists of six units of L-guluronic acid (G).
T76755	Panobacumab
	Panobacumab (KBPA101) 是一种完全人 IgM/κ 单克隆抗体，由人类 B 淋巴细胞产生，对血清型 O11P. aeruginosa 的 LPS O 多糖具有抗性。
T37902	Uridine-5'-diphosphoglucuronic Acid (sodium salt hydrate)
	Uridine-5'-diphosphoglucuronic acid is a nucleoside diphosphate sugar that is a source of glucuronic acid for polysaccharide biosynthesis. This compound can be used for the formation of many glucuronides with various aglycones.1 1.Green, M.D., and Tephly, T.R.Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteinsDrug Metab. Dispos.26(9)860-867(1998)
T37045	1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose
	1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-mannopyranose is an analog of N-acetylmannosamine (ManNAc) and a building block.1,2It has been used as a precursor in the synthesis of differently substituted trimers of the group AN. meningitidiscapsular polysaccharide repeating unit for use in immunological experiments.2It has also been used in the synthesis of fluorescent probes for lysosomal labeling.3
T79132	Du011
	Du011为针对MprA的大肠杆菌多糖胶囊生物发生抑制剂，用于探讨抗大肠杆菌感染的潜能。
T37900	UDP-Glucuronic Acid (sodium salt hydrate)
	UDP-Glucuronic acid is a nucleoside diphosphate sugar that is a source of glucuronic acid for polysaccharide biosynthesis. This compound can be used for the formation of many glucuronides with various aglycones.1 1.Green, M.D., and Tephly, T.R.Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteinsDrug Metab. Dispos.26(9)860-867(1998)
TNU1050	3-Deoxy-1,2;5,6-di-O-isopropylidene-D-glucofuranose
	3-Deoxy-1,2;5,6-di-O-isopropylidene-D-glucofuranose 是一种多糖类的低聚糖。它用于糖基化的合成，可以定制合成用作药物中的碳水化合物。它通过抑制病毒蛋白合成而对Epstein-Barr 病毒具有抗病毒活性。
T83672	TTAPE-Me 1,1,2,2-tetrakis[4-(2-Trimethylammonioethoxy)-phenylethene
	TTAPE-Me是一种聚集诱导发光(AIE)荧光团。它被用于检测阴离子磷脂，包括心磷脂、磷脂酰甘油(PG)和磷脂酰丝氨酸(PS)、核酸，以及阴离子多糖肝素。
T78343	Driselase
	Driselase是一种商业真菌原生质酶制剂，该复合壁消化酶混合物在测试多糖消化方面效率极高，并能显著提高材料的拉伸及压痕顺应性。即便经过6小时的消化作用，Driselase也不会引起壁蠕变现象。
T76585	Hepcidin-20 (human)
	Hepcidin-20 (human) 是一种β-折叠结构肽，含有组氨酸和丰富的半胱氨酸，具备抗真菌活性，并能抑制多糖细胞间粘附素 (PIA) 阳性及阴性菌株的生物膜形成及细菌细胞代谢[3]。
T75518	Galactofucan
	Galactofucan (Fucogalactan) 是一种硫酸多糖。Galactofucan 可以从棕色海藻 Saccharina longicruris 中提取，具有抗凝血、抗肿瘤、抗血栓形成、抗炎、抗病毒等特性。Galactofucan 对 HSV-1和 HSV-2具有抗病毒活性，IC50值分别为 0.76 和 1.34 µg/mL 。Galactofucan 可用于癌症和炎症的研究。
T69966	Roxadustat-d5
	Roxadustat-d5 is intended for use as an internal standard for the quantification of roxadustat by GC- or LC-MS. Roxadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH; IC50s = 1.4, 1.26, and 1.32 µM for HIF-PH1, HIF-PH2, and HIF-PH3, respectively). It is selective for HIF-PH over other 2-oxoglutarate-dependent dioxygenases, including lysine-specific demethylase 5A (KDM5A), KDM5B, -5C, -5D, and -6B (IC50s = >100 µM for all). Roxadustat (10-200 µM) stabilizes HIF-1α and ...

化合物

Polysaccharidase

Cat.No: T81424

Synonym: Tremella polysaccharide

Acetyl tetrapeptide-9 Acetate

Cat.No: TP2365L

Synonym: Acetyl tetrapeptide-9 Acetate(928006-50-2 Free base)

Target: Others

Cat.No: T40626

Target: Others

Cat.No: T10110

Synonym: 3-Carbethoxypsoralen,3-Ethoxycarbonylpsoralen

Target: Antibiotic

Heparin sodium salt

Cat.No: T6531

Synonym: 肝素钠,Sodium heparinate,Heparin sodium

Target: Factor Xa, Thrombin, Autophagy

L-Triguluronic acid

Cat.No: T38246

Bromophenol red

Cat.No: T71881

L-Pentaguluronic acid

Cat.No: T39278

L-Diguluronic acid disodium

Cat.No: T75673

Acetyl tetrapeptide-9

Cat.No: TP2365

Synonym: LS9745,N-Acetyl-gln-asp-val-his,Dermican,LS-9745,LS 9745

L-Tetraguluronic acid

Cat.No: T38982

L-Hexaguluronic acid

Cat.No: T39279

Cat.No: T76755

Uridine-5'-diphosphoglucuronic Acid (sodium salt hydrate)

Cat.No: T37902

1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose

Cat.No: T37045

Cat.No: T79132

UDP-Glucuronic Acid (sodium salt hydrate)

Cat.No: T37900

3-Deoxy-1,2;5,6-di-O-isopropylidene-D-glucofuranose

Cat.No: TNU1050

Cat.No: T83672

Synonym: 1,1,2,2-tetrakis[4-(2-Trimethylammonioethoxy)-phenylethene

Cat.No: T78343

Hepcidin-20 (human)

Cat.No: T76585

Cat.No: T75518

Cat.No: T69966

Cat. No.	Product Name	Target	Signaling Pathways
T7544	Fucoidan 岩藻多糖	Others	Others
	Fucoidan 是一种 α-淀粉酶和 α-葡萄糖苷酶的有效抑制剂，是一种生物特性多糖。它具有抗凝血，抗肿瘤，抗氧化和抗脂肪特性。
T20597	Alginic acid Protanal LF,褐藻酸,Snow acid algin G,Kelacid,Sazzio,Norgine	Apoptosis; Autophagy; Histamine Receptor	Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Alginic acid (Snow acid algin G) 是一种从褐海藻中提取的天然多糖，具有抗过敏和抗炎活性。 Alginic acid 抑制组胺释放，可用于食品工业。
T41078	Lipopolysaccharides, Escherichiacoli (11C) LPS E. coli O55:B5,Lipopolysaccharide, E. coli O111:B4	Others	Others
	Lipopolysaccharides, Escherichiacoli (11C) (LPS E. coli O55:B5)是革兰阴性菌外膜的大分子成分，由脂质a、寡糖核心和o -特异性多糖(O-antigen) 3个区域组成。
T11855	Lipopolysaccharides 脂多糖,LPS	Others	Others
	Lipopolysaccharides (LPS) 属于天然产物，是一种来源于革兰氏阴性菌外膜外叶的内毒素。Lipopolysaccharides 是一种高免疫原性抗原，可以增强免疫反应，可以用于炎症模型构建。
T22291	Chitin Chitin (From shrimp and crab shells)	Others	Others
	Chitin 是一种大型的结构多糖，存在于真菌的细胞壁、昆虫的外骨骼以及鱼类和无脊椎动物的某些坚硬结构中。
T19355	Heparan Sulfate 硫酸乙酰肝素,硫酸类肝素	FGFR; Wnt/beta-catenin; Endogenous Metabolite	Angiogenesis; Cytoskeletal Signaling; Metabolism; Stem Cells; Tyrosine Kinase/Adaptors
	Heparan sulfate 是一种复杂的线性多糖。Heparan sulfate 作为硫酸乙酰肝素蛋白聚糖的一部分出现，在细胞外基质和细胞表面表达丰富。
T5733	Xylotetraose	Others	Others
	Xylotetraose 是木聚糖的水解产物，可用于酶生化分析。Xylan 是由木糖单元组成的多糖，主要包含由纤维素连接的 β-D- 木糖单位。
T5043	Lentinan	Others	Others
	Lentinan 是一种 β-葡聚糖，从香菇中提取获得。它在日本已被批准用作胃癌的生物反应调节剂。
T1715	Chitosan (MW 150000) 壳聚糖,Chitosan,Poly(D-glucosamine),Deacetylated chitin	Antibacterial; Antifungal	Microbiology/Virology
	Chitosan (MW 150000) (Deacetylated chitin) 是衍生自几丁质的聚阳离子线性多糖。它无毒，具有低致敏性，生物相容性和可生物降解性。它还具有抗肿瘤，抗细菌，抗真菌和抗氧化活性。
T5120	Rhamnose 6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose	Calcium Channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	alpha-L-Rhamnose (6-Deoxy-L-mannose) 是存在植物和细菌中的一种单糖。Rhamnose- 免疫原连接物能被用于免疫疗法。Rhamnose 能通过胞外途径穿过上皮细胞，能够作为肠吸收的标志。
T4809	Pyrimidine 嘧啶,Metadiazine	Others; Endogenous Metabolite	Metabolism; Others
	Pyrimidine (Metadiazine) 是内源性代谢产物的一种。
T21027	Guar gum Guaran,Gum cyamopsis,Gum guar,Guar flour
	Guar gum is a galactomannan polysaccharide extracted from guar beans, it has stabilizing and thickening properties useful in food, feed, and industrial applications.
T11513	Gum arabic Arabic gum,阿拉伯胶	Others	Others
	Gum Arabic, a branched-chain, complex polysaccharide derived from A. Senegal, exhibits antioxidant properties and offers protection against experimental hepatic, renal, and cardiac toxicities. Additionally, it finds application in immunohistochemistry.
T38245	L-Diguluronic acid
	L-Diguluronic acid, a linear polysaccharide copolymer consisting of two L-guluronic acid (G) units, serves as a precursor for Alginate[1], a categorically unbranched polyanionic polysaccharide. Alginate finds application in the development of antifungal agent delivery carriers[2].
T72730	D-Isofloridoside
	D-Isofloridoside 是多糖前体之一，具有清除自由基、抑制ROS 表达、抑制MMP-2和MMP-9的活性。
T78497	λ-Carrageenan
	λ-Carrageenan是广泛应用于基础研究的海藻多糖，常用作促炎剂，并具有有效的抗肿瘤活性。
T82369	Fructo-oligosaccharide DP14
	Fructo-oligosaccharide DP14为从Atractylodes lancea中提取的寡糖。
T40589	6-O-β-D-Galactopyranosyl-D-galactose
	6-O-beta-D-Galactopyranosyl-D-galactose, a disaccharide, is a constituent of the polysaccharide backbone characterized by beta-(1→6) glycoside linkages, with a side chain attached to the primary chain through a beta-(1→3) bond.
TN6768	Amylopectin	Others	Others
	Amylopectin 是一种基于葡萄糖的高度支化的多糖。它与直链淀粉一起形成淀粉。支链淀粉的糖苷键为α-葡聚糖链α- 1、4和支链点α- 1，6。
T82751	Celloheptaose
	Celloheptaose为含七个葡萄糖残基的低聚糖，作为多糖单加氧酶(PMOs)的底物，催化形成氧化的纤维素寡糖。
T82750	Cellooctaose
	Cellooctaose，由8个葡萄糖残基构成的低聚糖，作为低成本的多糖，在发酵中能促进重组乳酸菌的生长。

天然产物

Cat.No: T7544

Synonym: 岩藻多糖

Target: Others

Cat.No: T20597

Synonym: Protanal LF,褐藻酸,Snow acid algin G,Kelacid,Sazzio,Norgine

Target: Apoptosis, Autophagy, Histamine Receptor

Lipopolysaccharides, Escherichiacoli (11C)

Cat.No: T41078

Synonym: LPS E. coli O55:B5,Lipopolysaccharide, E. coli O111:B4

Target: Others

Lipopolysaccharides

Cat.No: T11855

Synonym: 脂多糖,LPS

Target: Others

Cat.No: T22291

Synonym: Chitin (From shrimp and crab shells)

Target: Others

Heparan Sulfate

Cat.No: T19355

Synonym: 硫酸乙酰肝素,硫酸类肝素

Target: FGFR, Wnt/beta-catenin, Endogenous Metabolite

Cat.No: T5733

Target: Others

Cat.No: T5043

Target: Others

Chitosan (MW 150000)

Cat.No: T1715

Synonym: 壳聚糖,Chitosan,Poly(D-glucosamine),Deacetylated chitin

Target: Antibacterial, Antifungal

Cat.No: T5120

Synonym: 6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose

Target: Calcium Channel, Endogenous Metabolite

Cat.No: T4809

Synonym: 嘧啶,Metadiazine

Target: Others, Endogenous Metabolite

Cat.No: T21027

Synonym: Guaran,Gum cyamopsis,Gum guar,Guar flour

Cat.No: T11513

Synonym: Arabic gum,阿拉伯胶

Target: Others

L-Diguluronic acid

Cat.No: T38245

D-Isofloridoside

Cat.No: T72730

Cat.No: T78497

Fructo-oligosaccharide DP14

Cat.No: T82369

6-O-β-D-Galactopyranosyl-D-galactose

Cat.No: T40589

Cat.No: TN6768

Target: Others

Cat.No: T82751

Cat.No: T82750

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