17
4
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1532 |
Pidotimod
|
Others; Antibacterial | Microbiology/Virology; Others |
Pidotimod 是一种具有免疫调节特性的合成二肽。它增加巨噬细胞活性和体液免疫功能。它可研究慢性支气管炎、慢性阻塞性肺疾病 、支气管扩张、慢性特发性荨麻疹等。 | |||
T15543 |
IA-Alkyne
N-Hex-5-ynyl-2-iodo-acetamide,Iodoacetamide-alkyne |
TRP/TRPV Channel | Membrane transporter/Ion channel |
IA-Alkyne (Iodoacetamide-alkyne) 是TRP 通道 (TRPC) 的激动剂,有用于呼吸道感染相关疾病研究的潜力。IA-Alkyne 可以用于开发同位素标记的探针,在定量的半胱氨酸反应分析 (cysteine-reactivity)有应用的价值。 | |||
T0331 |
Moxifloxacin hydrochloride
盐酸莫西沙星,莫西沙星盐酸盐,BAY-128039,Moxifloxacin HCl,BAY12-8039 HCl |
Topoisomerase; Antibacterial; Antibiotic | DNA Damage/DNA Repair; Microbiology/Virology |
Moxifloxacin hydrochloride (BAY12-8039 HCl) 是一种口服有效的 8-甲氧基喹诺酮类抗菌药物,可研究感染性肺炎,急性细菌性鼻窦炎和慢性支气管炎的急性细菌性加重。 | |||
T4543 |
Telithromycin
HMR3647,泰利霉素,Ketek,RU66647 |
Antibacterial; Antibiotic | Microbiology/Virology |
Telithromycin (HMR3647) 是一种社区获得性肺炎抗生素。 | |||
T15447 |
Guacetisal
|
Others | Others |
Guacetisal 是从乙酰水杨酸与愈创木酚的酯化反应中提取的,可用于治疗慢性支气管炎的相关研究。 | |||
T68099 |
midesteine
MR-889 |
Others | Others |
Midesteine (MR-889) 是一种可逆、慢结合、完全竞争的蛋白酶抑制剂。 | |||
T0026 |
Sulfalene
磺胺林,Sulfalene(SMPZ),Sulfalen,SMP2,Butadiene sulfone,AS-18908,Sulfametopyrazine,3-Sulfolene |
Antibacterial; Antibiotic; Parasite; Autophagy | Autophagy; Microbiology/Virology |
Sulfalene (SMP2) 是一种长效磺胺类抗生素,用于治疗慢性支气管炎、尿路感染和疟疾。 | |||
T6547 |
Ipratropium Bromide
Sch 1000,异丙托溴铵,Itrop,Atrovent |
AChR | Neuroscience |
Ipratropium Bromide (Sch 1000) 是毒蕈碱的受体的拮抗剂,可用于 COPD 和哮喘等研究,对 M1、M2 和 M3 受体的结合的IC50值分别为 2.9、2 和 1.7 nM。 | |||
T10987 |
Decarboxy Moxifloxacin
|
Others | Others |
Decarboxy Moxifloxacin 是一种莫西沙星的脱羧化合物。Moxifloxacin 是一种能够口服的 8-甲氧基喹诺酮类抗菌药物,可用于急性细菌性鼻窦炎,慢性支气管炎的急性细菌性加重和感染性肺炎。 | |||
T2555 |
Aclidinium bromide
LAS 34273,LAS-W 330,阿地溴铵 |
AChR | Neuroscience |
Aclidinium bromide (LAS-W 330) 是长效可吸入型的毒蕈碱拮抗剂,有用于慢性阻塞性肺病 (COPD) 的研究潜力。 | |||
T23164 |
PIT
2,2'-Pyridylisatogen tosylate |
P2Y Receptor | GPCR/G Protein; Neuroscience |
PIT (2,2'-Pyridylisatogen tosylate) 是嘌呤能受体 P2Y1 的特异性非竞争性拮抗剂,对人 P2Y1 的 IC50 为 0.14 μM。 PIT 不影响核苷酸结合,可用于慢性支气管炎和哮喘的研究。 | |||
T26666 |
ASM-024
|
AChR | Neuroscience |
ASM-024是一种有效的烟碱受体激动剂,是一种小分子合成哌嗪化合物,可促进β2-肾上腺素受体不同的靶点和信号通路介导平滑肌松弛,是治疗哮喘和慢性阻塞性支气管炎的潜在化合物,具有抗炎活性。 | |||
T0910 |
Terpin hydrate
Terpin Monohydrate,cis-Terpin hydrate,萜品(水合结晶) |
Others | Others |
Terpin hydrate 是一种祛痰药,可除去急慢性支气管炎病人的黏液。 | |||
T26638 |
Antofloxacin Hydrochloride
(S)-Antofloxacin hydrochloride,Antofloxacin HCl |
||
Antofloxacin Hydrochloride, a fluoroquinolone antimicrobial, is used to treat acute exacerbation of chronic bronchitis (AECB), acute pyelonephritis(AP), acute cystitis and multiple folliculitis. | |||
T36993 |
Moxifloxacin N-Sulfate (sodium salt)
|
||
Moxifloxacin N-sulfate is a metabolite of moxifloxacin . Moxifloxacin is a fluoroquinolone antibiotic. Formulations containing moxifloxacin have been used in the treatment of bacterial infections, including sinusitis, chronic bronchitis, and pneumonia. | |||
T71286 |
Guaifenesin-d3
|
||
Guaifenesin-d3 is intended for use as an internal standard for the quantification of guaifenesin by GC- or LC-MS. Guaifenesin is an expectorant. It inhibits production of mucin 5AC (MUC5AC), reduces mucus viscosity and elasticity, and increases the mucociliary transport rate of endogenous particles in primary human tracheobronchial epithelial cells in a concentration-dependent manner. Guaifenesin increases phenol red secretion, a marker of expectorant activity, in rats.3 Formulations containing ... | |||
T70097 | Acefylline piperazine | ||
Acefylline piperazine is a stimulant drug of the xanthine chemical class. It acts as an adenosine receptor antagonist. Acephylline piperazine is a theophylline derivative with a direct bronchodilator action. It has the advantages over theophylline in being far less toxic and producing minimal gastric irritation. It is indicated for the treatment of asthma, emphysema, acute and chronic bronchitis associated with bronchospasm.Acefylline relaxes smooth muscles, relieves bronchospasm & has a stimula... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3872 |
Nodakenin
紫花前胡苷,(+)-Marmesinin |
AChE | Neuroscience |
Nodakenin ((+)-Marmesinin) 是一种Peucedanum decursivum Maxim 根中的主要香豆素苷。它能够抑制乙酰胆碱酯酶活性,IC50=84.7 μM。 | |||
TN5284 |
Sodium Houttuyfonate
Houttuynin sodium bisulfite,新鱼腥草素钠 |
NF-κB; Antibacterial; Antifungal | Microbiology/Virology; NF-κB |
Sodium Houttuyfonate (Houttuynin sodium bisulfite) 是亚硫酸氢钠与鱼腥草结合而成的活性化合物,具有抗真菌、抗菌、抗炎和心血管保护活性,主要用于治疗化脓性皮肤感染、呼吸道感染,包括老年患者的肺炎和慢性支气管炎。 | |||
T0892 |
Diphylline
二羟丙茶碱,Dyphylline,Diprophylline |
PDE; Adenosine Receptor | GPCR/G Protein; Metabolism; Neuroscience |
Diphylline (Diprophylline) 是一种A1/A2腺苷受体拮抗剂,也是环状核苷酸磷酸二酯酶抑制剂。它是一种黄嘌呤衍生物,具有支气管扩张和血管扩张作用,有用于治疗慢性支气管炎和肺气肿的潜力。 | |||
T75494 | Shinjulactone M | ||
Shinjulactone M 是一种从 Ailanthus 中分离出来的一种苦木苦味素类化合物。Ailanthus 可用作退热药 (抗疟) 和驱虫药,用于慢性支气管炎、癫痫和哮喘的研究。 |