Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Telithromycin (HMR3647) 是一种社区获得性肺炎抗生素。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 460 | 待询 | ||
5 mg | ¥ 1,170 | 待询 | ||
10 mg | ¥ 1,930 | 待询 | ||
25 mg | ¥ 4,170 | 待询 | ||
50 mg | ¥ 6,750 | 待询 | ||
100 mg | ¥ 9,830 | 待询 | ||
1 mL * 10 mM (in DMSO) | ¥ 1,290 | 待询 |
产品描述 | Telithromycin (HMR3647) is a ketolide antibiotic to treat community acquired pneumonia of mild to moderate severity. Antibacterial Telithromycin prevents bacteria from growing, by interfering with their protein synthesis. Telithromycin binds to the subunit 50S of the bacterial ribosome, and blocks the progression of the growing polypeptide chain. Telithromycin has over 10 times higher affinity to the subunit 50S than erythromycin. In addition, telithromycin strongly bind simultaneously to two domains of 23S RNA of the 50 S ribosomal subunit, where older macrolides bind strongly only to one domain and weakly to the second domain. Telithromycin can also inhibit the formation of ribosomal subunits 50S and 30S. |
别名 | HMR3647, 泰利霉素, Ketek, RU66647 |
分子量 | 812.02 |
分子式 | C43H65N5O10 |
CAS No. | 191114-48-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: Insoluble
Ethanol: 30 mg/mL
DMSO: 30 mg/mL
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Telithromycin 191114-48-4 Microbiology/Virology Antibacterial Antibiotic inhibit chronic bronchitis infections RAW 264.7 cells acute sinusitis HMR3647 immunomodulatory TNF-α Inhibitor 泰利霉素 bacteria HMR 3647 NF-kB RU-66647 Bacterial ketolide antibiotic Ketek MLE-12 cells RU 66647 RU66647 HMR-3647 inhibitor