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Search Results for " anti-alcohol "

8

抑制剂 & 化合物

16

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T11393	GET73 Gamma hydroxybutyric acid analogue,GET 73	GluR	Neuroscience
	GET73 (Gamma hydroxybutyric acid analogue) 是天然神经递质 γ-羟基丁酸的类似物。它对谷氨酸在海马的传递有显著的影响。它具有抗酒精和抗焦虑的作用。
T36520	COR659	Cannabinoid Receptor; GABA Receptor	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	COR659 是一种有效的 GABAB 的阳性变构调节剂。COR659具有缓解大鼠对酒精和巧克力成瘾的作用。
T68919	Nabumetone Alcohol
	Nabumetone alcohol is the alcohol form of nabumetone, a non-steroidal anti-inflammatory drug (NSAID) that is rapidly metabolized in the liver to a major active metabolite, 6-methoxy-2-naphthyl acetic acid, which inhibits the cyclooxygenase enzyme and preferentially blocks COX-2 activity (which is indirectly responsible for the production of inflammation and pain during arthritis).
T72259	3-Chlorogentisyl alcohol
	3-Chlorogentisyl alcohol 是一种有效的 E. coliβ-葡萄糖醛酸酶β-glucuronidase 抑制剂，IC50值为 0.74 µM，Ki 值为 0.58 µM。3-Chlorogentisyl alcohol 显示出抗增殖活性。3-Chlorogentisyl alcohol 具有抗癌和抗炎治疗研究的潜力。
T72864	Perillic acid 紫苏酸
	Perillic acid 是 Perillyl alcohol 的代谢物。Perillic acid 诱导肺癌细胞周期阻滞和凋亡 (apoptosis)。Perillic acid 具有抗HSV-1和免疫调节活性。
T70859	ent-Abacavir
	ent-Abacavir is an enatiomer of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuroni...
T37831	CAY10641
	Cytosolic phospholipase A2α (cPLA2α) specifically catalyzes the hydrolysis of arachidonic acid from thesn-2-ester position of membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes, both important mediators of the inflammatory process.1CAY10641 is an inactive alcohol derivative of a highly potent (IC50= 12 nM) cPLA2α inhibitor.2The parent compound demonstrates strong anti-inflammatory effects when applied topically at a dose of 0.1 mg/ear in...
T64692	AMY-101 acetate
	Complement component C3 plays a particularly versatile role in this process by keeping the cascade alert, acting as a point of convergence of activation pathways, fueling the amplification of the complement response, exerting direct effector functions, and helping to coordinate downstream immune responses[3]. In C3-/- mice alcohol-induced liver steatosis is absent or strongly reduced after chronic or acute alcohol exposure. This suggests that the complement system and its component C3 contribute...

化合物

Cat.No: T11393

Synonym: Gamma hydroxybutyric acid analogue,GET 73

Target: GluR

Cat.No: T36520

Target: Cannabinoid Receptor, GABA Receptor

Nabumetone Alcohol

Cat.No: T68919

3-Chlorogentisyl alcohol

Cat.No: T72259

Cat.No: T72864

Synonym: 紫苏酸

Cat.No: T70859

Cat.No: T37831

AMY-101 acetate

Cat.No: T64692

Cat. No.	Product Name	Target	Signaling Pathways
T2950	Schisandrin Wuweizi alcohol-A,Wuweizichun-A,Schizandrol-A,Schizandrol,五味子醇甲	Autophagy	Autophagy
	Schisandrin (Wuweizi alcohol-A) 是一种从五味子中分离出来的联苯环辛烯类木脂素，可逆转大鼠的记忆障碍，具有保肝、抗氧化、抗哮喘、抗癌和抗炎作用。
T6S1917	Schisandrol B Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B	P450; Reactive Oxygen Species; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Schisandrol B (Besigomsin) 是华中五味子的主要活性成分，具有保肝、抗炎、抗糖尿病和抗氧化的作用。它抑制活性氧的产生，也抑制 P-糖蛋白和CYP3A 的活性。
T8516	Levomenol 没药醇,(-)-α-BISABOLOL,(-)-α-红没药醇	Others	Others
	Levomenol ((-)-α-BISABOLOL) 是一种单环倍半萜醇，具有有神经保护、抗氧化、抗炎和抗凋亡的作用。它可减轻三叉神经性疼痛啮齿动物模型的伤害性行为和中枢敏感性。它通过减少小鼠永久性局灶性脑缺血诱导的促炎标志物，防止神经元损伤和记忆缺陷。
T2860	Vanillyl Alcohol 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,香兰醇,Vanillin alcohol,Vanillic alcohol	Apoptosis; Others	Apoptosis; Others
	Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) 是一种酚类醇，具有抗血管生成、抗惊厥、抗炎、抗氧化、神经保护和抗伤害活性。它由香兰素衍生而来，在食品和饮料中用作调味剂。
T8282	(S)-(−)-Perillyl alcohol Perillyl alcohol,(-)-Perillyl Alcohol,L-紫苏醇	Apoptosis; Endogenous Metabolite	Apoptosis; Metabolism
	(S)-(−)-Perillyl alcohol (Perillyl alcohol) 是一种在薰衣草中发现的单萜，可抑制 Ras 的法尼基化，上调 6-磷酸甘露糖受体并诱导细胞凋亡。它还具有抗癌活性。
T2916	Patchouli alcohol 百秋李醇,Patchouli camphor,Patchoulol,(-)-Patchouli Alcohol,广藿香醇	Antibacterial; Antifungal	Microbiology/Virology
	Patchouli alcohol (Patchoulol) 是一种从广藿香中提取的天然三环倍半萜，有抗幽门螺杆菌和抗炎活性。
T3752	4-Hydroxybenzyl alcohol 4-Methylolphenol,P-Methylolphenol,对羟基苯甲醇	Apoptosis; Endogenous Metabolite	Apoptosis; Metabolism
	4-Hydroxybenzyl alcohol (P-Methylolphenol) 是广泛分布于各种植物中的一种酚类天然产物，具有抗炎、抗氧化和抗伤害感受活性。它抑制肿瘤血管生成和生长，有神经保护作用。
TN1132	Procyanidin A2 原花青素 A2,原花青素A2	IL Receptor; TNF; transporter; Antibacterial	Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology
	Procyanidin A2 是一种具有抗癌、抗氧化、抗菌和抗炎活性的黄酮类天然产物，存在于蔓越莓和越橘中。
T5737	euphol	Others; Lipase; Endogenous Metabolite	Metabolism; Others
	Euphol 是从Euphorbia tirucalli 的汁液中分离出来的四环三萜醇，具有抗炎和免疫调节作用，口服具有活力。它通过能够逆机制抑制单酰基甘油脂肪酶 (MGL) 的特性，IC50=315 nM。外周 MGL 抑制能够调节内源性大麻素系统从而阻止炎症性疼痛的发展。
T3674	Hydroxysafflor yellow A 藏红花,羟基红花黄色素A,HSYA,Safflomin A	TGF-beta/Smad	Stem Cells
	Hydroxysafflor yellow A (Safflomin A) 是一种黄酮类天然产物，从中药红花中分离得到，具有抗癌作用。
T8733	Antrodin A (2-氯苯基)二苯基甲醇,camphorataanhydride A	Others	Others
	Antrodin A (camphorataanhydride A) 是固体发酵樟脑菌菌丝体的一种主要活性成分。它能够增强肝脏的抗炎及抗氧化能力，维持肠道菌群的稳定，避免酒精对肝脏的损伤。
T3254	PHYTOL 植醇,trans-Phytol,(E)-Phytol	Antibacterial; PPAR; Parasite	DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	PHYTOL (trans-Phytol) 是一种从叶绿素中提取的二萜醇，广泛应用于食品添加剂和医药领域，具有很好的抗血吸虫特性。它具有抗伤害、抗氧化、抗炎、抗过敏等作用。它对结核分枝杆菌和金黄色葡萄球菌具有抗菌活性。
T20006	Isopropyl palmitate EINECS 205-571-1,Isopropyl hexadecanoate,BRN 1786567,AI3-05733,Emcol-IP,HSDB 2647
	Isopropyl palmitate is the isopropyl alcohol and palmitic acid ester. It is a moisturizer, emollient, anti-static agent, and thickening agent.
T39570	Cycloartenyl ferulate Cycloartenolferulate,Cycloartenolferulicacidester,环木菠萝烯醇阿魏酸酯
	Cycloartenyl ferulate (also known as cycloartenol ferulate) is a representative triterpene alcohol with diverse biological properties, such as antioxidant, anti-allergic, anti-inflammatory, and anticancer activities.
T79976	Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside	HBV	Microbiology/Virology
	Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside 作为一种抗HBV剂，在Hep G2.2.15细胞系上能够抑制HBsAg和HBeAg的分泌，其IC50值分别约为1.67 mM和>2.15 mM。
T79975	Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside	HBV	Microbiology/Virology
	Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside（化合物1）是一种具有抗HBV活性的木脂素类化合物。该化合物对HBV表面抗原（HBsAg）的IC50为0.58 mM，而对HBV e抗原（HBeAg）的IC50 > 2.4 mM。其可从八角茴香中提取分离。

天然产物

Cat.No: T2950

Synonym: Wuweizi alcohol-A,Wuweizichun-A,Schizandrol-A,Schizandrol,五味子醇甲

Target: Autophagy

Cat.No: T6S1917

Synonym: Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B

Target: P450, Reactive Oxygen Species, Autophagy

Cat.No: T8516

Synonym: 没药醇,(-)-α-BISABOLOL,(-)-α-红没药醇

Target: Others

Vanillyl Alcohol

Cat.No: T2860

Synonym: 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,香兰醇,Vanillin alcohol,Vanillic alcohol

Target: Apoptosis, Others

(S)-(−)-Perillyl alcohol

Cat.No: T8282

Synonym: Perillyl alcohol,(-)-Perillyl Alcohol,L-紫苏醇

Target: Apoptosis, Endogenous Metabolite

Patchouli alcohol

Cat.No: T2916

Synonym: 百秋李醇,Patchouli camphor,Patchoulol,(-)-Patchouli Alcohol,广藿香醇

Target: Antibacterial, Antifungal

4-Hydroxybenzyl alcohol

Cat.No: T3752

Synonym: 4-Methylolphenol,P-Methylolphenol,对羟基苯甲醇

Target: Apoptosis, Endogenous Metabolite

Cat.No: TN1132

Synonym: 原花青素 A2,原花青素A2

Target: IL Receptor, TNF, transporter, Antibacterial

Cat.No: T5737

Target: Others, Lipase, Endogenous Metabolite

Hydroxysafflor yellow A

Cat.No: T3674

Synonym: 藏红花,羟基红花黄色素A,HSYA,Safflomin A

Target: TGF-beta/Smad

Cat.No: T8733

Synonym: (2-氯苯基)二苯基甲醇,camphorataanhydride A

Target: Others

Cat.No: T3254

Synonym: 植醇,trans-Phytol,(E)-Phytol

Target: Antibacterial, PPAR, Parasite

Isopropyl palmitate

Cat.No: T20006

Synonym: EINECS 205-571-1,Isopropyl hexadecanoate,BRN 1786567,AI3-05733,Emcol-IP,HSDB 2647

Cycloartenyl ferulate

Cat.No: T39570

Synonym: Cycloartenolferulate,Cycloartenolferulicacidester,环木菠萝烯醇阿魏酸酯

Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside

Cat.No: T79976

Target: HBV

Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside

Cat.No: T79975

Target: HBV

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