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Targets Recommended: FXR RAR/RXR 

58

抑制剂 & 化合物

1

TargetMol 试剂盒

24

重组蛋白

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Cat. No. Product Name Form Specificity Of Inhibition
CL0099 RAR/RXR agonist kit

RAR/RXR agonist kit

TargetMol 试剂盒

RAR/RXR agonist kit
Cat.No: CL0099
Cat. No. Product Name Target Signaling Pathways
T35187 XR 5944

XR-5944,MLN-944,MLN944,XR5944,MLN 944

XR 5944 is an effective DNA binder that stabilizes topoisomerase-dependent cleavage and has shown superior efficacy in a variety of mouse and human tumor models.
T26339L XR-11576 HCl

XR-11576 HCl(346689-77-8 Free base)

Topoisomerase DNA Damage/DNA Repair
XR-11576 HCl 是一种新型口服活性拓扑异构酶I 和II 双重抑制剂,具有抗肿瘤活性。
T35188 XR 808

XR808,XR-808

XR 808 is a biochemical.
T15143 DMP-543

XR-543

Others; Potassium Channel Membrane transporter/Ion channel; Others
DMP-543 (XR-543) 是一种钾离子通道 (KV7 channel) 阻滞剂。DMP-543可以增强神经递质的释放。
T35186 XR 334

XR-334,XR334

XR 334 is a biochemical.
T26339 XR-11576

MLN-576,MLN 576,MLN576,XR 11576

XR-11576 is a DNA topoisomerase I and II inhibitor for the treatment of solid tumors.
T70417 XR 1853

XR 1853 is a low molecular weight modulator of human plasminogen activator inhibitor-1 activity.
T29168 XR-5000

NSC-601316,CRC8805,SN-22995,DACA,CRC-8805

XR-5000 is a DNA topoisomerase I and II inhibitor.
T30356 USAF XR-37

Benzenecarboximidamide, 4,4'-iminobis-, dihydrochloride (9CI)

Benzenecarboximidamide, 4,4'-iminobis-, dihydrochloride (9CI) is a bioactive chemical.
T21233 Dihydrolipoic acid

Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid,二氢硫辛酸

Antioxidant oxidation-reduction
Dihydrolipoic acid (USAF XR-12) 是高效的抗氧化剂,对所有以氧为中心的自由基都有很强的清除能力。它在多种疾病中表现出抗炎特性。在 LPS 诱导的疾病行为大鼠中,它通过 ERK/Nrf2/HO-1/ROS/NLRP3 通路发挥预防作用。它还可以可用于抑郁症的研究。
T32397 Kinoprene

XR 777,XR-777,XR777

Kinoprene is a biochemical.
T68737 XR9051

XR9051 is as a potent modulator of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) following a synthetic chemistry programme based on a natural product lead compound. XR9051 was shown to be a potent inhibitor of the binding of the cytotoxic to P-glycoprotein (EC50 = 1.4 +/- 0.5 nM). XR9051 reverses the MDR phenotype through direct interaction with P-glycoprotein.
T6287L Tariquidar dimesylate

D 06008,XR9576,D06008,XR 9576,Tariquidar dimesilate,XR-9576

Tariquidar is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs.
T125507 Antibiotic XR 586

Antibiotic XR 586 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125507,CAS号为 185981-24-2。
T6287 Tariquidar

XR9576,他立喹达

P-gp Membrane transporter/Ion channel; Neuroscience
Tariquidar (XR9576) 是一种特异性有效的P-糖蛋白抑制剂,Kd 为 5.1 nM。
T69618 XR3054

XR3054 is a novel inhibitor of farnesyl protein transferase (FPTase). XR3054 inhibited the proliferation of the prostatic cancer cell lines LnCAP and PC3 and the colon carcinoma SW480 and HT1080 (IC50 values of 12.4, 12.2, 21.4 and 8.8 microM, respectively) but was relatively inactive when tested against a panel of breast carcinoma cell lines. The activity did not relate to the presence of mutant or wild-type ras in the cell lines tested. In conclusion XR3054 inhibits ras farnesylation, MAP kina...
T32758 Linagliptin mixture with metformin

Jentadueto Xr,Linagliptin / metformin,Jentadueto

Linagliptin mixture with metformin is used for the treatment of type 2 diabetes.
T32040 Halauxifen

XDE 729,XDE729,DE-729,XDE-729,XR-729

Halauxifen is a biochemical.
T20028 Janumet

Efficib,Janumet XR,Metformin / sitagliptin,Metformin hydrochloride mixture with sitagliptin phosphate

Metformin hydrochloride mixture with sitagliptin phosphate is an AMP-activated protein kinase stimulant. It is also a CD26 antigen inhibitor, Gluconeogenesis inhibitor, and Glucose modulator.
T27531 Hedaquinium chloride

BIQ 16,Teoquil,B1Q 16,USAF XR-39,Teoquil chloride

Hedaquinium chloride has antibacterial activity.
T29169 XR9051 Hydrochloride

XR9051 Hydrochloride, a potent modulator of P-glycoprotein-mediated multidrug resistance (MDR), inhibits the binding of cytotoxics to P-glycoprotein.
T72186 Tariquidar dihydrochloride

XR9576 dihydrochloride

Tariquidar dihydrochloride (XR9576 dihydrochloride) 是一种有效的特异性 P-glycoprotein(P-gp) 抑制剂,Kd 为 5.1 nM。
T69617 ER-67880

ER-67880 is a novel and potent microtubule inhibitor with potential anticancer activity.
T70416 PD 154075

PD 154075 is a a non-peptide tachykinin NK1 receptor antagonist.
T63443 XR8-89

XR8-89, 作为一种高效的类木瓜蛋白酶(PLpro)抑制剂,展现出0.1 μM的IC50值。通过诱导SARS-COV-2木瓜蛋白酶样蛋白酶的构象变化,XR8-89抑制了SARS-COV-2的复制,适用于SARS-CoV-2相关研究。
T62928 XR8-69

XR8-69 是一种 SARS-CoV-2 PLpro 抑制剂。XR8-69 在 SARS-CoV-2 感染的人类细胞中具有低微摩尔抗病毒作用。
T41255 Specific PXR antagonist 70

Others Others
Specific PXR antagonist 70 是一种特异性孕烷 X 受体 (PXR) 拮抗剂,对人源 PXR 的 IC50 为 540 nM,Ki 为 390 nM,可增强癌细胞的化学敏感性。
T13360 XRK3F2

Autophagy Autophagy
XRK3F2 是 p62-ZZ 结构域的抑制剂,在体外减弱 MM 诱导的 Runx2 抑制,在体内肿瘤存在的情况下诱导新骨形成和重塑。
T1783 LXR-623

LXR623,WAY 252623

Liver X Receptor Metabolism
LXR-623 (WAY 252623) 是一种LXRα部分激动剂和LXRβ完全激动剂,可透过血脑屏障,IC50分别为 179 nM 和 24 nM 。
T20759 XRP44X

XRP-44-X,XRP 44X,XRP-44X,XRP 44 X

Ras GPCR/G Protein; MAPK
XRP44X (XRP 44X) 是Ras 诱导的转录激活的抑制剂,IC50为 10 nM,通过 FGF-2 抑制 Ras-Erk-1/2 通路激活。它抑制Elk3。它还对微管有影响。
T22305 Dexrazoxane

右雷佐生,ICRF-187

Others Others
Dexrazoxane (ICRF-187) 是一种心脏保护剂。
T29017 TrxR1-IN-B19

TrxR1INB19,Go Y015,TrxR1 IN B19,Go-Y015

Others Others
TrxR1-IN-B19 (TrxR1 IN B19) 是一种 TrxR1 抑制剂,通过靶向 TrxR1 和 ROS 介导的 ER 应激激活,通过小分子选择性杀死胃癌细胞。
T62021 TrxR-IN-2

TrxR-IN-2 是潜在的硫氧还蛋白还原酶(TrxR)抑制剂。TrxR-IN-2在治疗耐药性肝细胞癌中有研究价值。
T64171 LXR antagonist 2

LXR antagonist 2 (compound 10rr) 是一种有效的 LXR (肝 X 受体) 反向激动剂,能够作用于 LXRβ (IC50: 0.36 μM) 和 LXRα (IC50: 2.25 μM)。 LXR antagonist 2 是一种脂肪生成抑制剂,能够下调 LXR 靶基因 SREBP-1c、ACC、FAS 和 SCD-1。LXR antagonist 2 对 Triton WR-1339 诱导的高脂血症小鼠表现出降脂活性。
T69273 Mexrenoate potassium

Mexrenoate potassium is a steroidal aldosterone antagonist and antihypertensive.
T35189 XRD 489

XRD489,XRD-489,D 489

XRD 489 is a biochemical.
T63723 LXR agonist 1

LXR (Liver X receptor) agonist 1 是 LXR 的有效激动剂,能够作用于 LXR-α (AC50: 1.5 nM) 和 LXR-β (AC50: 12 nM)。LXR agonist 1 对动脉粥样硬化表现出研究潜力。
T74754 FXR antagonist 2

Compound A-26, also known as FXR antagonist 2, is a diarylamide derivative that functions as a moderate FXR antagonist. It is utilized in researching hyperlipidemia and type 2 diabetes [1].
T64144 FXR antagonist 1

FXR antagonist 1 是一种选择性的、口服具有活力的肠道 FXR 拮抗剂,其 IC50 值为 2.1 μM。FXR antagonist 1 能够拮抗肠道 FXR,并反馈激活肝脏 FXR,进而选择性地抑制肠道 FXR 信号。FXR antagonist 1 可改善 NASH (非酒精性脂肪性肝炎) 模型中的肝脏脂肪变性、炎症和纤维化,能够用于研究 NASH。
T60453 TrxR-IN-3

TrxR-IN-3 (Compound 2c) 是TrxR 的有效抑制剂。TrxR-IN-3 对五种人类癌细胞系表现出强大的抗增殖活性,特别是对乳腺肿瘤细胞。TrxR-IN-3 增加 ROS 水平并通过调节乳腺癌细胞中细胞凋亡相关蛋白的表达导致明显的细胞凋亡。TrxR-IN-3 还通过促进 LC3-II 和 Beclin-1 的表达并减少 LC3-I 和 p62 蛋白的表达,来触发自噬体和自溶酶体的形成。
T83885 DXR Inhibitor 11a sodium

1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitor 11a

DXR抑制剂11a是P. falciparum 1-去氧-D-木糖-5-磷酸还原异构酶(DXR; IC50 = 0.11 µM)的抑制剂。它抑制在分离的人类红细胞中P. falciparum的生长(IC50 = 0.37 µM)。
T75160 FXR agonist 5

FXR agonist5 (compound 1) 是一种FXR 激动剂。FXR agonist5 可用于研究代谢性炎症引起的疾病或紊乱。
T41062 HXR9

HXR9 is a cell-permeable peptide that acts as a competitive antagonist of the HOX/PBX interaction. It effectively inhibits the binding between HOX proteins and the transcription factor PBX, specifically in paralogue groups 1 to 8. HXR9 selectively impairs cell proliferation and induces apoptosis in cells with a high expression of the HOXA/PBX3 genes, for instance, MLL-rearranged leukemic cells.
T11899 LXRβ agonist-2

Others Others
LXRβ agonist-2 is a highly potent and β-selective liver X receptor (LXRβ) agonist with EC50 of 7 nM.
T29018 TrxR inhibitor D9

D9,TrxR-IN-D9

TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR).
T63597 RXR antagonist 2

RXR antagonist 2 是一种 RXR 的有效拮抗剂 (Ki: 0.391 μM, Kd: 0.281 μM)。RXR antagonist 2 对 RXR 相关疾病表现出研究潜力。
T73254 TrxR-IN-4

TrxR-IN-4 (Compound 1b) 是一种针对 TrxR 的有效抑制剂,能够通过激活 ERS 诱导 HepG2 细胞的凋亡。此外,TrxR-IN-4 通过下调 TrxR 表达量和降低炎症水平,有效改善了 CCl4 诱导的肝损伤。
T83908 DXR Inhibitor 11a (free acid)

1-Deoxy-D-Xylulose-5-phosphate Reductoisomerase Inhibitor 11a

DXR inhibitor 11a是一种针对P. falciparum 1-脱氧-D-木糖-5-磷酸还原异构酶(DXR; IC50 = 0.11 µM)的抑制剂。它能够抑制在分离的人类红细胞中P. falciparum的生长(IC50 = 0.37 µM)。
T61647 TrxR-IN-5

TrxR-IN-5 (compound 4f) is an efficacious inhibitor of TrxR (thioredoxin reductase) with an IC50 of 0.16 μM. By elevating the levels of reactive oxygen species (ROS), TrxR-IN-5 fosters robust antiproliferative impacts. Additionally, TrxR-IN-5 demonstrates pronounced effects against cancer proliferation and metastasis [1].
T74996 FXR agonist 3

FXR agonist3 是一种抗 NASH 试剂,通过激活 FXR 起作用。FXR agonist3 抑制 COL1A1、TGF-β1、α-SMA 和 TIMP1的表达,具有抗纤维化活性。FXR agonist3 显著减轻肝脏脂肪变性和炎症,改善肝纤维化水平。

化合物

XR 5944
Cat.No: T35187
Synonym: XR-5944,MLN-944,MLN944,XR5944,MLN 944
Target:
XR-11576 HCl
Cat.No: T26339L
Synonym: XR-11576 HCl(346689-77-8 Free base)
Target: Topoisomerase
XR 808
Cat.No: T35188
Synonym: XR808,XR-808
Target:
DMP-543
Cat.No: T15143
Synonym: XR-543
Target: Others, Potassium Channel
XR 334
Cat.No: T35186
Synonym: XR-334,XR334
Target:
XR-11576
Cat.No: T26339
Synonym: MLN-576,MLN 576,MLN576,XR 11576
Target:
XR 1853
Cat.No: T70417
Synonym:
Target:
XR-5000
Cat.No: T29168
Synonym: NSC-601316,CRC8805,SN-22995,DACA,CRC-8805
Target:
USAF XR-37
Cat.No: T30356
Synonym: Benzenecarboximidamide, 4,4'-iminobis-, dihydrochloride (9CI)
Target:
Dihydrolipoic acid
Cat.No: T21233
Synonym: Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid,二氢硫辛酸
Target: Antioxidant
Kinoprene
Cat.No: T32397
Synonym: XR 777,XR-777,XR777
Target:
XR9051
Cat.No: T68737
Synonym:
Target:
Tariquidar dimesylate
Cat.No: T6287L
Synonym: D 06008,XR9576,D06008,XR 9576,Tariquidar dimesilate,XR-9576
Target:
Antibiotic XR 586
Cat.No: T125507
Synonym:
Target:
Tariquidar
Cat.No: T6287
Synonym: XR9576,他立喹达
Target: P-gp
XR3054
Cat.No: T69618
Synonym:
Target:
Linagliptin mixture with metformin
Cat.No: T32758
Synonym: Jentadueto Xr,Linagliptin / metformin,Jentadueto
Target:
Halauxifen
Cat.No: T32040
Synonym: XDE 729,XDE729,DE-729,XDE-729,XR-729
Target:
Janumet
Cat.No: T20028
Synonym: Efficib,Janumet XR,Metformin / sitagliptin,Metformin hydrochloride mixture with sitagliptin phosphate
Target:
Hedaquinium chloride
Cat.No: T27531
Synonym: BIQ 16,Teoquil,B1Q 16,USAF XR-39,Teoquil chloride
Target:
XR9051 Hydrochloride
Cat.No: T29169
Synonym:
Target:
Tariquidar dihydrochloride
Cat.No: T72186
Synonym: XR9576 dihydrochloride
Target:
ER-67880
Cat.No: T69617
Synonym:
Target:
PD 154075
Cat.No: T70416
Synonym:
Target:
XR8-89
Cat.No: T63443
Synonym:
Target:
XR8-69
Cat.No: T62928
Synonym:
Target:
Specific PXR antagonist 70
Cat.No: T41255
Synonym:
Target: Others
XRK3F2
Cat.No: T13360
Synonym:
Target: Autophagy
LXR-623
Cat.No: T1783
Synonym: LXR623,WAY 252623
Target: Liver X Receptor
XRP44X
Cat.No: T20759
Synonym: XRP-44-X,XRP 44X,XRP-44X,XRP 44 X
Target: Ras
Dexrazoxane
Cat.No: T22305
Synonym: 右雷佐生,ICRF-187
Target: Others
TrxR1-IN-B19
Cat.No: T29017
Synonym: TrxR1INB19,Go Y015,TrxR1 IN B19,Go-Y015
Target: Others
TrxR-IN-2
Cat.No: T62021
Synonym:
Target:
LXR antagonist 2
Cat.No: T64171
Synonym:
Target:
Mexrenoate potassium
Cat.No: T69273
Synonym:
Target:
XRD 489
Cat.No: T35189
Synonym: XRD489,XRD-489,D 489
Target:
LXR agonist 1
Cat.No: T63723
Synonym:
Target:
FXR antagonist 2
Cat.No: T74754
Synonym:
Target:
FXR antagonist 1
Cat.No: T64144
Synonym:
Target:
TrxR-IN-3
Cat.No: T60453
Synonym:
Target:
DXR Inhibitor 11a sodium
Cat.No: T83885
Synonym: 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitor 11a
Target:
FXR agonist 5
Cat.No: T75160
Synonym:
Target:
HXR9
Cat.No: T41062
Synonym:
Target:
LXRβ agonist-2
Cat.No: T11899
Synonym:
Target: Others
TrxR inhibitor D9
Cat.No: T29018
Synonym: D9,TrxR-IN-D9
Target:
RXR antagonist 2
Cat.No: T63597
Synonym:
Target:
TrxR-IN-4
Cat.No: T73254
Synonym:
Target:
DXR Inhibitor 11a (free acid)
Cat.No: T83908
Synonym: 1-Deoxy-D-Xylulose-5-phosphate Reductoisomerase Inhibitor 11a
Target:
TrxR-IN-5
Cat.No: T61647
Synonym:
Target:
FXR agonist 3
Cat.No: T74996
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-03460 DCXR Protein, Human, Recombinant (His)

XR,P34H,HCR2,HCRII,PNTSU,SDR20C1,DCR,dicarbonyl/L-x...

Human E. coli
DCXR, also known as HCR2, belongs to the short-chain dehydrogenases/reductases (SDR) family. It is highly expressed in kidney, liver and epididymis. In the epididymis, DCXR is mainly expressed in the proximal and distal sections of the corpus region. HCR2 is weakly or not expressed in brain, lung, heart, spleen and testis. DCXR catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. DCXR participates in the uronate cycle of...
TMPK-01331 TSLPR Protein, Cynomolgus, Recombinant (His)

CRL2,CRLF2,IL-XR,CRLF2Y,p2RY8/CRLF2 fusion,TSLPR,TS...

Cynomolgus HEK293 Cells
Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of the IL-7 receptor alpha chain (IL-7Ralpha) and the TSLP receptor (TSLPR, also known as CRLF2).
TMPJ-00530 TSLPR Protein, Mouse, Recombinant (hFc)

CRLF2,CRL2 cytokine receptor,TSLPR,CRL2,P2RY8/CRLF2 fusion,I...

Mouse HEK293 Cells
TSLPR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 62-88 KDa and the accession number is AAH23788.1.
TMPJ-00531 TSLPR Protein, Mouse, Recombinant (His)

Cytokine receptor-like 2,Thymic stromal-derived lymphopoieti...

Mouse HEK293 Cells
TSLPR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-40 KDa and the accession number is AAH23788.1.
TMPK-01151 MXRA8 Protein, Human, Recombinant (His)

Asp3,Limitrin,Adipocyte-specific 3,DICAM,Adipocyte-specific ...

Human HEK293 Cells
Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses. MXRA8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 36.70 kDa and the accession number is Q9BRK3-1.
TMPY-02953 TEM8/ANTXR1 Protein, Human, Recombinant (hFc)

ATR,TEM8,anthrax toxin receptor 1,GAPO

Human HEK293 Cells
ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are serine-threonine protein kinases and belongs to the phosphatidylinositol 3' kinase-like kinase (PIKK) family. Upon recruitment by the DNA damage binding proteins/complexes (ATRIP for ATR; MRN for ATM), ATM/ATR initiate the DNA damage checkpoint by phosphorylating a number of key pro...
TMPH-02512 TEM8/ANTXR1 Protein, Mouse, Recombinant (His)

Mouse E. coli
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells.
TMPK-00702 ANTXR2 Protein, Human, Recombinant (His)

cI-35,Antxr2,JHS,CMG-2,CMG2,JHF,HFS,ISH

Human HEK293 Cells
The Capillary Morphogenesis Gene 2 (CMG2) gene encodes an Anthrax toxin receptor (ANTXR2),ANTXR2/CMG2 was originally identified as a result of up-regulation during capillary morphogenesis of endothelial cells (ECs) cultured in vitro. ANTXR2/CMG2 functions to promote endothelial proliferation and morphogenesis during sprouting angiogenesis, consistent with the endothelial expression of ANTXR2/CMG2 in several vascular beds.
TMPH-02314 XRCC5 Protein, Human, Recombinant (His & MBP)

Human Baculovirus Insect Cells
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind...
TMPH-03167 toxR Protein, Pseudomonas aeruginosa, Recombinant (His)

Pseudomonas aeruginosa E. coli
Positive regulation of toxA gene transcription. toxR Protein, Pseudomonas aeruginosa, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.9 kDa and the accession number is P09852.
TMPY-00615 ANTXR2 Protein, Mouse, Recombinant (hFc)

AW561899,anthrax toxin receptor 2,2310046B19Rik,CMG-2,CMG2,c...

Mouse HEK293 Cells
ANTXR2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.9 kDa and the accession number is Q3TCL6.
TMPK-01166 MXRA8 Protein, Mouse, Recombinant (His)

Asp3,DICAM,Adipocyte-specific protein 3,Adipocyte-specific 3...

Mouse HEK293 Cells
Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses. MXRA8 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.11 kDa and the accession number is Q9DBV4.
TMPH-01747 FDXR Protein, Human, Recombinant (His & SUMO)

Human E. coli
Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. FDXR Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 61.6 kDa and the accession number is P22570.
TMPY-05000 NPTXR Protein, Human, Recombinant (His)

neuronal pentraxin receptor,NPR

Human HEK293 Cells
NPTXR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.8 kDa and the accession number is O95502.
TMPH-01819 LXR-alpha Protein, Human, Recombinant (His & Myc)

Human E. coli
LXR-alpha Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.1 kDa and the accession number is Q13133.
TMPY-02271 TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)

thioredoxin reductase 1,TR1,TXNR,TR,TRXR1,GRIM-12

Human E. coli
Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor th...
TMPJ-01333 TEM8/ANTXR1 Protein, Human, Recombinant (His)

ATR,ANTXR1,TEM8,Tumor Endothelial Marker 8,Anthrax ...

Human HEK293 Cells
Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It ...
TMPH-01355 FXR1 Protein, Human, Recombinant (His)

Human E. coli
RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs. FXR1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 70.5 kDa and the accession number is P51114.
TMPH-02315 XRCC5 Protein, Human, Recombinant (His & Myc)

Human E. coli
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind...
TMPY-04094 ANTXR2 Protein, Mouse, Recombinant (His)

cI-35,CMG2,2310046B19Rik,CMG-2,anthrax toxin receptor 2,AW56...

Mouse HEK293 Cells
ANTXR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q3TCL6.
TMPH-02686 GLXR Protein, Mouse, Recombinant (His & SUMO)

Mouse E. coli
Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.
TMPH-02513 TEM8/ANTXR1 Protein, Mouse, Recombinant (His & Myc)

Mouse HEK293 Cells
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells.
TMPH-02807 NPTXR Protein, Mouse, Recombinant (His & Myc)

Mouse Baculovirus Insect Cells
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
TMPY-00380 ANTXR2 Protein, Human, Recombinant (hFc)

HFS,JHF,anthrax toxin receptor 2,ISH,CMG-2,CMG2

Human HEK293 Cells
ANTXR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.4 kDa and the accession number is P58335-4.

重组蛋白

DCXR Protein, Human, Recombinant (His)
Cat.No: TMPY-03460
Species: Human
Expression System: E. coli
TSLPR Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01331
Species: Cynomolgus
Expression System: HEK293 Cells
TSLPR Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00530
Species: Mouse
Expression System: HEK293 Cells
TSLPR Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00531
Species: Mouse
Expression System: HEK293 Cells
MXRA8 Protein, Human, Recombinant (His)
Cat.No: TMPK-01151
Species: Human
Expression System: HEK293 Cells
TEM8/ANTXR1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02953
Species: Human
Expression System: HEK293 Cells
TEM8/ANTXR1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02512
Species: Mouse
Expression System: E. coli
ANTXR2 Protein, Human, Recombinant (His)
Cat.No: TMPK-00702
Species: Human
Expression System: HEK293 Cells
XRCC5 Protein, Human, Recombinant (His & MBP)
Cat.No: TMPH-02314
Species: Human
Expression System: Baculovirus Insect Cells
toxR Protein, Pseudomonas aeruginosa, Recombinant (His)
Cat.No: TMPH-03167
Species: Pseudomonas aeruginosa
Expression System: E. coli
ANTXR2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-00615
Species: Mouse
Expression System: HEK293 Cells
MXRA8 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01166
Species: Mouse
Expression System: HEK293 Cells
FDXR Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01747
Species: Human
Expression System: E. coli
NPTXR Protein, Human, Recombinant (His)
Cat.No: TMPY-05000
Species: Human
Expression System: HEK293 Cells
LXR-alpha Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01819
Species: Human
Expression System: E. coli
TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)
Cat.No: TMPY-02271
Species: Human
Expression System: E. coli
TEM8/ANTXR1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01333
Species: Human
Expression System: HEK293 Cells
FXR1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01355
Species: Human
Expression System: E. coli
XRCC5 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02315
Species: Human
Expression System: E. coli
ANTXR2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04094
Species: Mouse
Expression System: HEK293 Cells
GLXR Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02686
Species: Mouse
Expression System: E. coli
TEM8/ANTXR1 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02513
Species: Mouse
Expression System: HEK293 Cells
NPTXR Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02807
Species: Mouse
Expression System: Baculovirus Insect Cells
ANTXR2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00380
Species: Human
Expression System: HEK293 Cells
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