58
1
24
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
CL0099 |
RAR/RXR agonist kit
RAR/RXR agonist kit |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35187 |
XR 5944
XR-5944,MLN-944,MLN944,XR5944,MLN 944 |
||
XR 5944 is an effective DNA binder that stabilizes topoisomerase-dependent cleavage and has shown superior efficacy in a variety of mouse and human tumor models. | |||
T26339L |
XR-11576 HCl
XR-11576 HCl(346689-77-8 Free base) |
Topoisomerase | DNA Damage/DNA Repair |
XR-11576 HCl 是一种新型口服活性拓扑异构酶I 和II 双重抑制剂,具有抗肿瘤活性。 | |||
T35188 |
XR 808
XR808,XR-808 |
||
XR 808 is a biochemical. | |||
T15143 |
DMP-543
XR-543 |
Others; Potassium Channel | Membrane transporter/Ion channel; Others |
DMP-543 (XR-543) 是一种钾离子通道 (KV7 channel) 阻滞剂。DMP-543可以增强神经递质的释放。 | |||
T35186 |
XR 334
XR-334,XR334 |
||
XR 334 is a biochemical. | |||
T26339 |
XR-11576
MLN-576,MLN 576,MLN576,XR 11576 |
||
XR-11576 is a DNA topoisomerase I and II inhibitor for the treatment of solid tumors. | |||
T70417 |
XR 1853
|
||
XR 1853 is a low molecular weight modulator of human plasminogen activator inhibitor-1 activity. | |||
T29168 |
XR-5000
NSC-601316,CRC8805,SN-22995,DACA,CRC-8805 |
||
XR-5000 is a DNA topoisomerase I and II inhibitor. | |||
T30356 |
USAF XR-37
Benzenecarboximidamide, 4,4'-iminobis-, dihydrochloride (9CI) |
||
Benzenecarboximidamide, 4,4'-iminobis-, dihydrochloride (9CI) is a bioactive chemical. | |||
T21233 |
Dihydrolipoic acid
Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid,二氢硫辛酸 |
Antioxidant | oxidation-reduction |
Dihydrolipoic acid (USAF XR-12) 是高效的抗氧化剂,对所有以氧为中心的自由基都有很强的清除能力。它在多种疾病中表现出抗炎特性。在 LPS 诱导的疾病行为大鼠中,它通过 ERK/Nrf2/HO-1/ROS/NLRP3 通路发挥预防作用。它还可以可用于抑郁症的研究。 | |||
T32397 |
Kinoprene
XR 777,XR-777,XR777 |
||
Kinoprene is a biochemical. | |||
T68737 |
XR9051
|
||
XR9051 is as a potent modulator of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) following a synthetic chemistry programme based on a natural product lead compound. XR9051 was shown to be a potent inhibitor of the binding of the cytotoxic to P-glycoprotein (EC50 = 1.4 +/- 0.5 nM). XR9051 reverses the MDR phenotype through direct interaction with P-glycoprotein. | |||
T6287L |
Tariquidar dimesylate
D 06008,XR9576,D06008,XR 9576,Tariquidar dimesilate,XR-9576 |
||
Tariquidar is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. | |||
T125507 |
Antibiotic XR 586
|
||
Antibiotic XR 586 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125507,CAS号为 185981-24-2。 | |||
T6287 |
Tariquidar
XR9576,他立喹达 |
P-gp | Membrane transporter/Ion channel; Neuroscience |
Tariquidar (XR9576) 是一种特异性有效的P-糖蛋白抑制剂,Kd 为 5.1 nM。 | |||
T69618 |
XR3054
|
||
XR3054 is a novel inhibitor of farnesyl protein transferase (FPTase). XR3054 inhibited the proliferation of the prostatic cancer cell lines LnCAP and PC3 and the colon carcinoma SW480 and HT1080 (IC50 values of 12.4, 12.2, 21.4 and 8.8 microM, respectively) but was relatively inactive when tested against a panel of breast carcinoma cell lines. The activity did not relate to the presence of mutant or wild-type ras in the cell lines tested. In conclusion XR3054 inhibits ras farnesylation, MAP kina... | |||
T32758 |
Linagliptin mixture with metformin
Jentadueto Xr,Linagliptin / metformin,Jentadueto |
||
Linagliptin mixture with metformin is used for the treatment of type 2 diabetes. | |||
T32040 |
Halauxifen
XDE 729,XDE729,DE-729,XDE-729,XR-729 |
||
Halauxifen is a biochemical. | |||
T20028 |
Janumet
Efficib,Janumet XR,Metformin / sitagliptin,Metformin hydrochloride mixture with sitagliptin phosphate |
||
Metformin hydrochloride mixture with sitagliptin phosphate is an AMP-activated protein kinase stimulant. It is also a CD26 antigen inhibitor, Gluconeogenesis inhibitor, and Glucose modulator. | |||
T27531 |
Hedaquinium chloride
BIQ 16,Teoquil,B1Q 16,USAF XR-39,Teoquil chloride |
||
Hedaquinium chloride has antibacterial activity. | |||
T29169 |
XR9051 Hydrochloride
|
||
XR9051 Hydrochloride, a potent modulator of P-glycoprotein-mediated multidrug resistance (MDR), inhibits the binding of cytotoxics to P-glycoprotein. | |||
T72186 |
Tariquidar dihydrochloride
XR9576 dihydrochloride |
||
Tariquidar dihydrochloride (XR9576 dihydrochloride) 是一种有效的特异性 P-glycoprotein(P-gp) 抑制剂,Kd 为 5.1 nM。 | |||
T69617 |
ER-67880
|
||
ER-67880 is a novel and potent microtubule inhibitor with potential anticancer activity. | |||
T70416 |
PD 154075
|
||
PD 154075 is a a non-peptide tachykinin NK1 receptor antagonist. | |||
T63443 |
XR8-89
|
||
XR8-89, 作为一种高效的类木瓜蛋白酶(PLpro)抑制剂,展现出0.1 μM的IC50值。通过诱导SARS-COV-2木瓜蛋白酶样蛋白酶的构象变化,XR8-89抑制了SARS-COV-2的复制,适用于SARS-CoV-2相关研究。 | |||
T62928 |
XR8-69
|
||
XR8-69 是一种 SARS-CoV-2 PLpro 抑制剂。XR8-69 在 SARS-CoV-2 感染的人类细胞中具有低微摩尔抗病毒作用。 | |||
T41255 |
Specific PXR antagonist 70
|
Others | Others |
Specific PXR antagonist 70 是一种特异性孕烷 X 受体 (PXR) 拮抗剂,对人源 PXR 的 IC50 为 540 nM,Ki 为 390 nM,可增强癌细胞的化学敏感性。 | |||
T13360 |
XRK3F2
|
Autophagy | Autophagy |
XRK3F2 是 p62-ZZ 结构域的抑制剂,在体外减弱 MM 诱导的 Runx2 抑制,在体内肿瘤存在的情况下诱导新骨形成和重塑。 | |||
T1783 |
LXR-623
LXR623,WAY 252623 |
Liver X Receptor | Metabolism |
LXR-623 (WAY 252623) 是一种LXRα部分激动剂和LXRβ完全激动剂,可透过血脑屏障,IC50分别为 179 nM 和 24 nM 。 | |||
T20759 |
XRP44X
XRP-44-X,XRP 44X,XRP-44X,XRP 44 X |
Ras | GPCR/G Protein; MAPK |
XRP44X (XRP 44X) 是Ras 诱导的转录激活的抑制剂,IC50为 10 nM,通过 FGF-2 抑制 Ras-Erk-1/2 通路激活。它抑制Elk3。它还对微管有影响。 | |||
T22305 |
Dexrazoxane
右雷佐生,ICRF-187 |
Others | Others |
Dexrazoxane (ICRF-187) 是一种心脏保护剂。 | |||
T29017 |
TrxR1-IN-B19
TrxR1INB19,Go Y015,TrxR1 IN B19,Go-Y015 |
Others | Others |
TrxR1-IN-B19 (TrxR1 IN B19) 是一种 TrxR1 抑制剂,通过靶向 TrxR1 和 ROS 介导的 ER 应激激活,通过小分子选择性杀死胃癌细胞。 | |||
T62021 | TrxR-IN-2 | ||
TrxR-IN-2 是潜在的硫氧还蛋白还原酶(TrxR)抑制剂。TrxR-IN-2在治疗耐药性肝细胞癌中有研究价值。 | |||
T64171 | LXR antagonist 2 | ||
LXR antagonist 2 (compound 10rr) 是一种有效的 LXR (肝 X 受体) 反向激动剂,能够作用于 LXRβ (IC50: 0.36 μM) 和 LXRα (IC50: 2.25 μM)。 LXR antagonist 2 是一种脂肪生成抑制剂,能够下调 LXR 靶基因 SREBP-1c、ACC、FAS 和 SCD-1。LXR antagonist 2 对 Triton WR-1339 诱导的高脂血症小鼠表现出降脂活性。 | |||
T69273 | Mexrenoate potassium | ||
Mexrenoate potassium is a steroidal aldosterone antagonist and antihypertensive. | |||
T35189 |
XRD 489
XRD489,XRD-489,D 489 |
||
XRD 489 is a biochemical. | |||
T63723 | LXR agonist 1 | ||
LXR (Liver X receptor) agonist 1 是 LXR 的有效激动剂,能够作用于 LXR-α (AC50: 1.5 nM) 和 LXR-β (AC50: 12 nM)。LXR agonist 1 对动脉粥样硬化表现出研究潜力。 | |||
T74754 |
FXR antagonist 2
|
||
Compound A-26, also known as FXR antagonist 2, is a diarylamide derivative that functions as a moderate FXR antagonist. It is utilized in researching hyperlipidemia and type 2 diabetes [1]. | |||
T64144 |
FXR antagonist 1
|
||
FXR antagonist 1 是一种选择性的、口服具有活力的肠道 FXR 拮抗剂,其 IC50 值为 2.1 μM。FXR antagonist 1 能够拮抗肠道 FXR,并反馈激活肝脏 FXR,进而选择性地抑制肠道 FXR 信号。FXR antagonist 1 可改善 NASH (非酒精性脂肪性肝炎) 模型中的肝脏脂肪变性、炎症和纤维化,能够用于研究 NASH。 | |||
T60453 |
TrxR-IN-3
|
||
TrxR-IN-3 (Compound 2c) 是TrxR 的有效抑制剂。TrxR-IN-3 对五种人类癌细胞系表现出强大的抗增殖活性,特别是对乳腺肿瘤细胞。TrxR-IN-3 增加 ROS 水平并通过调节乳腺癌细胞中细胞凋亡相关蛋白的表达导致明显的细胞凋亡。TrxR-IN-3 还通过促进 LC3-II 和 Beclin-1 的表达并减少 LC3-I 和 p62 蛋白的表达,来触发自噬体和自溶酶体的形成。 | |||
T83885 |
DXR Inhibitor 11a sodium
1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitor 11a |
||
DXR抑制剂11a是P. falciparum 1-去氧-D-木糖-5-磷酸还原异构酶(DXR; IC50 = 0.11 µM)的抑制剂。它抑制在分离的人类红细胞中P. falciparum的生长(IC50 = 0.37 µM)。 | |||
T75160 | FXR agonist 5 | ||
FXR agonist5 (compound 1) 是一种FXR 激动剂。FXR agonist5 可用于研究代谢性炎症引起的疾病或紊乱。 | |||
T41062 |
HXR9
|
||
HXR9 is a cell-permeable peptide that acts as a competitive antagonist of the HOX/PBX interaction. It effectively inhibits the binding between HOX proteins and the transcription factor PBX, specifically in paralogue groups 1 to 8. HXR9 selectively impairs cell proliferation and induces apoptosis in cells with a high expression of the HOXA/PBX3 genes, for instance, MLL-rearranged leukemic cells. | |||
T11899 |
LXRβ agonist-2
|
Others | Others |
LXRβ agonist-2 is a highly potent and β-selective liver X receptor (LXRβ) agonist with EC50 of 7 nM. | |||
T29018 |
TrxR inhibitor D9
D9,TrxR-IN-D9 |
||
TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR). | |||
T63597 | RXR antagonist 2 | ||
RXR antagonist 2 是一种 RXR 的有效拮抗剂 (Ki: 0.391 μM, Kd: 0.281 μM)。RXR antagonist 2 对 RXR 相关疾病表现出研究潜力。 | |||
T73254 | TrxR-IN-4 | ||
TrxR-IN-4 (Compound 1b) 是一种针对 TrxR 的有效抑制剂,能够通过激活 ERS 诱导 HepG2 细胞的凋亡。此外,TrxR-IN-4 通过下调 TrxR 表达量和降低炎症水平,有效改善了 CCl4 诱导的肝损伤。 | |||
T83908 |
DXR Inhibitor 11a (free acid)
1-Deoxy-D-Xylulose-5-phosphate Reductoisomerase Inhibitor 11a |
||
DXR inhibitor 11a是一种针对P. falciparum 1-脱氧-D-木糖-5-磷酸还原异构酶(DXR; IC50 = 0.11 µM)的抑制剂。它能够抑制在分离的人类红细胞中P. falciparum的生长(IC50 = 0.37 µM)。 | |||
T61647 | TrxR-IN-5 | ||
TrxR-IN-5 (compound 4f) is an efficacious inhibitor of TrxR (thioredoxin reductase) with an IC50 of 0.16 μM. By elevating the levels of reactive oxygen species (ROS), TrxR-IN-5 fosters robust antiproliferative impacts. Additionally, TrxR-IN-5 demonstrates pronounced effects against cancer proliferation and metastasis [1]. | |||
T74996 |
FXR agonist 3
|
||
FXR agonist3 是一种抗 NASH 试剂,通过激活 FXR 起作用。FXR agonist3 抑制 COL1A1、TGF-β1、α-SMA 和 TIMP1的表达,具有抗纤维化活性。FXR agonist3 显著减轻肝脏脂肪变性和炎症,改善肝纤维化水平。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03460 |
DCXR Protein, Human, Recombinant (His)
XR,P34H,HCR2,HCRII,PNTSU,SDR20C1,DCR,dicarbonyl/L-x... |
Human | E. coli |
DCXR, also known as HCR2, belongs to the short-chain dehydrogenases/reductases (SDR) family. It is highly expressed in kidney, liver and epididymis. In the epididymis, DCXR is mainly expressed in the proximal and distal sections of the corpus region. HCR2 is weakly or not expressed in brain, lung, heart, spleen and testis. DCXR catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. DCXR participates in the uronate cycle of... | |||
TMPK-01331 |
TSLPR Protein, Cynomolgus, Recombinant (His)
CRL2,CRLF2,IL-XR,CRLF2Y,p2RY8/CRLF2 fusion,TSLPR,TS... |
Cynomolgus | HEK293 Cells |
Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of the IL-7 receptor alpha chain (IL-7Ralpha) and the TSLP receptor (TSLPR, also known as CRLF2). | |||
TMPJ-00530 |
TSLPR Protein, Mouse, Recombinant (hFc)
CRLF2,CRL2 cytokine receptor,TSLPR,CRL2,P2RY8/CRLF2 fusion,I... |
Mouse | HEK293 Cells |
TSLPR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 62-88 KDa and the accession number is AAH23788.1. | |||
TMPJ-00531 |
TSLPR Protein, Mouse, Recombinant (His)
Cytokine receptor-like 2,Thymic stromal-derived lymphopoieti... |
Mouse | HEK293 Cells |
TSLPR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-40 KDa and the accession number is AAH23788.1. | |||
TMPK-01151 |
MXRA8 Protein, Human, Recombinant (His)
Asp3,Limitrin,Adipocyte-specific 3,DICAM,Adipocyte-specific ... |
Human | HEK293 Cells |
Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses. MXRA8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 36.70 kDa and the accession number is Q9BRK3-1. | |||
TMPY-02953 |
TEM8/ANTXR1 Protein, Human, Recombinant (hFc)
ATR,TEM8,anthrax toxin receptor 1,GAPO |
Human | HEK293 Cells |
ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are serine-threonine protein kinases and belongs to the phosphatidylinositol 3' kinase-like kinase (PIKK) family. Upon recruitment by the DNA damage binding proteins/complexes (ATRIP for ATR; MRN for ATM), ATM/ATR initiate the DNA damage checkpoint by phosphorylating a number of key pro... | |||
TMPH-02512 |
TEM8/ANTXR1 Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. | |||
TMPK-00702 |
ANTXR2 Protein, Human, Recombinant (His)
cI-35,Antxr2,JHS,CMG-2,CMG2,JHF,HFS,ISH |
Human | HEK293 Cells |
The Capillary Morphogenesis Gene 2 (CMG2) gene encodes an Anthrax toxin receptor (ANTXR2),ANTXR2/CMG2 was originally identified as a result of up-regulation during capillary morphogenesis of endothelial cells (ECs) cultured in vitro. ANTXR2/CMG2 functions to promote endothelial proliferation and morphogenesis during sprouting angiogenesis, consistent with the endothelial expression of ANTXR2/CMG2 in several vascular beds. | |||
TMPH-02314 |
XRCC5 Protein, Human, Recombinant (His & MBP)
|
Human | Baculovirus Insect Cells |
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind... | |||
TMPH-03167 |
toxR Protein, Pseudomonas aeruginosa, Recombinant (His)
|
Pseudomonas aeruginosa | E. coli |
Positive regulation of toxA gene transcription. toxR Protein, Pseudomonas aeruginosa, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.9 kDa and the accession number is P09852. | |||
TMPY-00615 |
ANTXR2 Protein, Mouse, Recombinant (hFc)
AW561899,anthrax toxin receptor 2,2310046B19Rik,CMG-2,CMG2,c... |
Mouse | HEK293 Cells |
ANTXR2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.9 kDa and the accession number is Q3TCL6. | |||
TMPK-01166 |
MXRA8 Protein, Mouse, Recombinant (His)
Asp3,DICAM,Adipocyte-specific protein 3,Adipocyte-specific 3... |
Mouse | HEK293 Cells |
Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses. MXRA8 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.11 kDa and the accession number is Q9DBV4. | |||
TMPH-01747 |
FDXR Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. FDXR Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 61.6 kDa and the accession number is P22570. | |||
TMPY-05000 |
NPTXR Protein, Human, Recombinant (His)
neuronal pentraxin receptor,NPR |
Human | HEK293 Cells |
NPTXR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.8 kDa and the accession number is O95502. | |||
TMPH-01819 |
LXR-alpha Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
LXR-alpha Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.1 kDa and the accession number is Q13133. | |||
TMPY-02271 |
TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)
thioredoxin reductase 1,TR1,TXNR,TR,TRXR1,GRIM-12 |
Human | E. coli |
Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor th... | |||
TMPJ-01333 |
TEM8/ANTXR1 Protein, Human, Recombinant (His)
ATR,ANTXR1,TEM8,Tumor Endothelial Marker 8,Anthrax ... |
Human | HEK293 Cells |
Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It ... | |||
TMPH-01355 |
FXR1 Protein, Human, Recombinant (His)
|
Human | E. coli |
RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs. FXR1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 70.5 kDa and the accession number is P51114. | |||
TMPH-02315 |
XRCC5 Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind... | |||
TMPY-04094 |
ANTXR2 Protein, Mouse, Recombinant (His)
cI-35,CMG2,2310046B19Rik,CMG-2,anthrax toxin receptor 2,AW56... |
Mouse | HEK293 Cells |
ANTXR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q3TCL6. | |||
TMPH-02686 |
GLXR Protein, Mouse, Recombinant (His & SUMO)
|
Mouse | E. coli |
Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate. | |||
TMPH-02513 |
TEM8/ANTXR1 Protein, Mouse, Recombinant (His & Myc)
|
Mouse | HEK293 Cells |
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. | |||
TMPH-02807 |
NPTXR Protein, Mouse, Recombinant (His & Myc)
|
Mouse | Baculovirus Insect Cells |
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. | |||
TMPY-00380 |
ANTXR2 Protein, Human, Recombinant (hFc)
HFS,JHF,anthrax toxin receptor 2,ISH,CMG-2,CMG2 |
Human | HEK293 Cells |
ANTXR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.4 kDa and the accession number is P58335-4. |