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Search Results for " ufo "

Targets Recommended: Histamine Receptor

19

抑制剂 & 化合物

17

天然产物

11

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T68146	Sufotidine AH 25352X,AH25352X,AH-25352X	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Sufotidine (AH 25352X) 是一种具有高度选择性的竞争性 H2 受体拮抗剂。
T15390	Glufosfamide D 19575,Glucosylifosfamide mustard	Others	Others
	Glufosfamide 是一种新型噁唑磷胺化合物，具有抗癌活性，可用于研究晚期非小细胞肺癌。
T20029	Buformin hydrochloride NSC528218,NSC-528218,盐酸丁双胍,NSC 528218	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	Buformin hydrochloride (NSC-528218) 是一种有效的 AMPK 激活剂，是一种双胍类的口服抗糖尿病药物。Buformin 延缓胃肠道对葡萄糖的吸收，增加胰岛素敏感性和葡萄糖对细胞的吸收，并抑制肝脏对葡萄糖的合成。Buformin 也具有抗癌活性，可用于各种癌症研究。
T15391	Glufosinate ammonium	Others	Others
	Glufosinate ammonium 是谷氨酸的一种膦酸类似物，是一种除草剂，在植物细胞中转化为 PT (L-phosphinothricin) 。Glufosinate ammonium 显示出神经毒性作用。
T31224	Piflufolastat DCFPYL	Epigenetic Reader Domain	Chromatin/Epigenetic
	Piflufolastat (DCFPYL) 是一种针对前列腺癌 PSMA 的 PET 显像剂。是一种含氟前列腺特异性膜抗原（PSMA）制剂。Piflufolastat 可用于制备 piflufolastat F 18 (DCFPyL F-18)。
T61011	Izuforant
	Izuforant (JW1601) (Compound 24) 具有有效的抗炎和止痒活性。 Izuforant 对人血清素3受体 (h5-HT3R) 具有结合亲和力，IC50值为 9.1 μM。它也是组胺 H4 受体 (H4R) 的口服活性拮抗剂，对人 H4R 的IC50值为 36 nM。
T32590	Lauformine
	Lauformine is a isoquinoline alkaloid.
T131542	Arenobufagin (Arenobufogenin)
	Arenobufagin (Arenobufogenin) 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131542。
T30610	Bufotoxin Vulgarobufotoxin
	Bufotoxin, a toxic steroid lactone, exists in the parotoid glands, skin, and poison of many toads and other amphibians, and in some plants and mushrooms.
T15391L	Glufosinate	Others	Others
	Glufosinate, a phosphinic acid analog of glutamic acid, is a herbicide that is converted by plant cells into PT (L-phosphinothricin). It has neurotoxic activity.
T10116	3-O-Acetylbufotalin	Others	Others
	3-O-Acetylbufotalin is a derivate of bufadienolide with anti-cancer activity.
T125720	Ajuforrestin A
	Ajuforrestin A 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125720。
T27146	Denufosol tetrasodium INS37217,INS 37217,INS-37217
	Denufosol is a P2Y2 agonist potentially for the treatment of cystic fibrosis.
T20772	Crufomate Ruelene,M 1261,M1261,Crufomatum,M-1261
	Crufomate, an insecticide, is used extensively for the control of hornflies, cattle grubs and cattle lice.
T23837	Buformin 丁双胍,W37,W 37,H 224,W-37
	Buformin (1-butylbiguanide) is an oral antidiabetic drug of the biguanide class. It also inhibits the synthesis of glucose by the liver. Buformin delays absorption of glucose from the gastrointestinal tract increases insulin sensitivity and glucose uptake
T75992	Buforin II
	Buforin II，来源于 buforin I，从亚洲蟾蜍 Bufo bufo gargarizans 胃中分离得到的蛋白，是一种高效的抗菌 (antimicrobial) 肽。Buforin II 对广谱的革兰氏阳性和革兰氏阴性细菌具有抗菌活性。
T124283	5beta-Hydroxybufotalin
	5beta-Hydroxybufotalin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124283。
T131543	Gamabufotalin (Gamabufagin; Gamabufogenin)
	Gamabufotalin (Gamabufagin; Gamabufogenin) 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131543。
T76864	Enapotamab	TAM Receptor	Tyrosine Kinase/Adaptors
	Enapotamab 是一种 AXL/UFO 相关抗体，可用于合成抗体-药物偶联物（Enapotamab Vedotin）。

化合物

Cat.No: T68146

Synonym: AH 25352X,AH25352X,AH-25352X

Target: Histamine Receptor

Cat.No: T15390

Synonym: D 19575,Glucosylifosfamide mustard

Target: Others

Buformin hydrochloride

Cat.No: T20029

Synonym: NSC528218,NSC-528218,盐酸丁双胍,NSC 528218

Target: AMPK

Glufosinate ammonium

Cat.No: T15391

Target: Others

Cat.No: T31224

Synonym: DCFPYL

Target: Epigenetic Reader Domain

Cat.No: T61011

Cat.No: T32590

Arenobufagin (Arenobufogenin)

Cat.No: T131542

Cat.No: T30610

Synonym: Vulgarobufotoxin

Cat.No: T15391L

Target: Others

3-O-Acetylbufotalin

Cat.No: T10116

Target: Others

Cat.No: T125720

Denufosol tetrasodium

Cat.No: T27146

Synonym: INS37217,INS 37217,INS-37217

Cat.No: T20772

Synonym: Ruelene,M 1261,M1261,Crufomatum,M-1261

Cat.No: T23837

Synonym: 丁双胍,W37,W 37,H 224,W-37

Cat.No: T75992

5beta-Hydroxybufotalin

Cat.No: T124283

Gamabufotalin (Gamabufagin; Gamabufogenin)

Cat.No: T131543

Cat.No: T76864

Target: TAM Receptor

Cat. No.	Product Name	Target	Signaling Pathways
T4A2399	Cinobufotalin 华蟾毒它灵,华蟾素	IL Receptor; Akt; MRP; P-gp	Cytoskeletal Signaling; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; PI3K/Akt/mTOR signaling
	Cinobufotalin 是一种从蟾蜍的皮肤分泌物中提取的强心类固醇或丁二烯内酯。它已被用作强心药，利尿药和止血药，也是潜在的抗肺癌药物。
T4A2456	Gamabufotalin Gamabufagin,日本蟾蜍毒苷元	COX	Immunology/Inflammation; Neuroscience
	Gamabufotalin (Gamabufagin) 是一种蟾蜍甾烯，存在于蟾酥中。它稳定性高，毒性低，被广泛用于癌症的研究。
T4A2458	Resibufogenin 酯蟾毒配基,Bufogenin,Recibufogenin,酯蟾毒配基，蟾力苏	Others	Others
	Resibufogenin (Bufogenin) 是华蟾素的成分之一，表现出抑制氧化应激及肿瘤再生的活性。
TN7062L	Bufotenidine hydrochloride(487-91-2 Free base)
	Bufotenidine hydrochloride(487-91-2 Free base) 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN7062L，CAS号为 40581-89-3。
T5A2461	Bufotalin 蟾蜍他灵,Bufotaline,蟾毒它灵,蟾蜍他灵	Apoptosis; Others; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; Others
	Bufotalin (Bufotaline) 是一种从蟾酥中分离的类固醇内酯，可诱导癌细胞凋亡，也诱导内质网应激的激活，具有强大的抗肿瘤活性。
TN2877	3,4-Dihydroxy-2-O-methylanigorufone	Others	Others
	3,4-Dihydroxy-2-O-methylanigorufone 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2877，CAS号为 1392307-42-4。
TN4238	Hydroxyanigorufone	Others	Others
	Hydroxyanigorufone is a natural product from Musa itinerans Cheesm.
TN1912	Marinobufogenin 南美蟾毒精,Marinobufagenin	ATPase; EGFR	Angiogenesis; JAK/STAT signaling; Membrane transporter/Ion channel; Tyrosine Kinase/Adaptors
	Marinobufagenin, a cardiotonic steroid, its increased concentrations are important in the cardiac disease and oxidant stress state seen with renal failure.
TN2787	2-O-Methylanigorufone	Others	Others
	2-O-Methylanigorufone is a natural product from Monochoria vaginalis.
TN3035	4'-Hydroxy-2-O-methylanigorufone	Others	Others
	9-(4'-Hydroxyphenyl)-2-methoxyphenalen-1-one(4'-Hydroxy-2-O-methylanigorufone) is a phytoalexin. It shows a strong α-glucosidase inhibitory effect.
T5527	Anigorufone	Antifection	Microbiology/Virology
	Anigorufone is a phytoalexin, it shows striking antinematode activity. Anigorufone has shown inhibitory activity on the growth of the germinative tube of Fusarium oxysporum f. sp. cubense race 4.
T83282	5β-Hydroxybufotalin
	5β-Hydroxybufotalin (化合物 6) 是一种来源于中药蟾酥的天然产物，具有有效的抗癌作用，能够抑制癌细胞的生长活性。
T82808	Bufoserotonin C
	Bufoserotonin C为蟾酥中新发现的吲哚生物碱，展现出对抗肿瘤的活性。其在A549细胞系中的IC50为34.3 μM。
TN1200	19-Oxocinobufotalin	Others	Others
	19-Oxocinobufotalin 3-adipoylarginine ester shows significant inhibition effect against human hepatocellular carcinoma cell line SMMC-7721 in vitro.
T82807	Bufospirostenin A
	Bufospirostenin A是首次从动物体内分离得到的螺甾醇类化合物。
TN1572	Desacetylcinobufotalin	Others	Others
	Desacetylcinobufotalin has significant antitumor activity through induction apoptosis via mitochondria pathway, it also shows potent cytotoxic activities against HL-60 cell lines.
T31876	Frangufoline
	Frangufoline is a sedative 14-membered frangulanine-type cyclopeptide alkaloid.

天然产物

Cat.No: T4A2399

Synonym: 华蟾毒它灵,华蟾素

Target: IL Receptor, Akt, MRP, P-gp

Cat.No: T4A2456

Synonym: Gamabufagin,日本蟾蜍毒苷元

Target: COX

Cat.No: T4A2458

Synonym: 酯蟾毒配基,Bufogenin,Recibufogenin,酯蟾毒配基，蟾力苏

Target: Others

Bufotenidine hydrochloride(487-91-2 Free base)

Cat.No: TN7062L

Cat.No: T5A2461

Synonym: 蟾蜍他灵,Bufotaline,蟾毒它灵,蟾蜍他灵

Target: Apoptosis, Others, Reactive Oxygen Species

3,4-Dihydroxy-2-O-methylanigorufone

Cat.No: TN2877

Target: Others

Hydroxyanigorufone

Cat.No: TN4238

Target: Others

Marinobufogenin

Cat.No: TN1912

Synonym: 南美蟾毒精,Marinobufagenin

Target: ATPase, EGFR

2-O-Methylanigorufone

Cat.No: TN2787

Target: Others

4'-Hydroxy-2-O-methylanigorufone

Cat.No: TN3035

Target: Others

Cat.No: T5527

Target: Antifection

5β-Hydroxybufotalin

Cat.No: T83282

Bufoserotonin C

Cat.No: T82808

19-Oxocinobufotalin

Cat.No: TN1200

Target: Others

Bufospirostenin A

Cat.No: T82807

Desacetylcinobufotalin

Cat.No: TN1572

Target: Others

Cat.No: T31876

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01601	AXL Protein, Human, Recombinant (His) UFO,ARK,JTK11,AXL receptor tyrosine kinase,Tyro7	Human	HEK293 Cells
	AXL Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.5 kDa and the accession number is AAB20305.1.
TMPJ-00449	AXL Protein, Human, Recombinant (hFc) UFO,Tyrosine-protein kinase receptor UFO,A...	Human	HEK293 Cells
	AXL Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-115 KDa and the accession number is AAA61243.
TMPJ-00399	AXL Protein, Mouse, Recombinant (hFc) Tyrosine-protein kinase receptor UFO,UFO,A...	Mouse	HEK293 Cells
	AXL Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is Q00993.
TMPY-01021	AXL Protein, Mouse, Recombinant (His & hFc) AI323647,AXL receptor tyrosine kinase,Tyro7,Ufo,Ark	Mouse	HEK293 Cells
	AXL Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 74.5 kDa and the accession number is Q00993.
TMPY-06478	AXL Protein, Human, Recombinant (mFc) UFO,JTK11,ARK,Tyro7,AXL receptor tyrosine kinase	Human	HEK293 Cells
	AXL Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 72.11 kDa and the accession number is AAH32229.1.
TMPY-01364	AXL Protein, Mouse, Recombinant (His) Ark,AXL receptor tyrosine kinase,Ufo,Tyro7,AI323647	Mouse	HEK293 Cells
	AXL Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.8 kDa and the accession number is Q00993.
TMPK-00410	AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated ARK,EC 2.7.10.1,EC 2.7.10,Axl,JTK11,AXL oncogene,UFO	Human	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein (Primary Amine Labeling), Human, Rec...
TMPK-00408	AXL Protein, Human, Recombinant (His & Avi), Biotinylated AXL oncogene,EC 2.7.10.1,AI323647,Axl,JTK11,ARK,EC 2.7.10,	Human	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Human, Recombinant (His & Avi), Bio...
TMPK-00407	AXL Protein, Human, Recombinant (His & Avi) AXL oncogene,Axl,EC 2.7.10.1,Tyro7,UFO,ARK,EC 2.7.1...	Human	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Human, Recombinant (His & Avi) is e...
TMPK-00472	AXL Protein, Cynomolgus, Recombinant (His) Tyro7,JTK11,AI323647,AXL oncogene,EC 2.7.10.1,EC 2.7.10,...	Cynomolgus	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Cynomolgus, Recombinant (His) is ex...
TMPJ-01081	Dtk Protein, Human, Recombinant (His) RSE,SKY,DTK,Tyrosine-protein kinase DTK,Tyrosine-protein kin...	Human	HEK293 Cells
	Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs and two fibronectin type III motifs. This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases. All three receptors bind the vitamin K-dependent protein growth-arrest specific gene 6 (Gas6) which is structurally related to th...

重组蛋白

AXL Protein, Human, Recombinant (His)

Cat.No: TMPY-01601

Species: Human

Expression System: HEK293 Cells

AXL Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00449

Species: Human

Expression System: HEK293 Cells

AXL Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00399

Species: Mouse

Expression System: HEK293 Cells

AXL Protein, Mouse, Recombinant (His & hFc)

Cat.No: TMPY-01021

Species: Mouse

Expression System: HEK293 Cells

AXL Protein, Human, Recombinant (mFc)

Cat.No: TMPY-06478

Species: Human

Expression System: HEK293 Cells

AXL Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01364

Species: Mouse

Expression System: HEK293 Cells

AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated

Cat.No: TMPK-00410

Species: Human

Expression System: HEK293 Cells

AXL Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00408

Species: Human

Expression System: HEK293 Cells

AXL Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00407

Species: Human

Expression System: HEK293 Cells

AXL Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00472

Species: Cynomolgus

Expression System: HEK293 Cells

Dtk Protein, Human, Recombinant (His)

Cat.No: TMPJ-01081

Species: Human

Expression System: HEK293 Cells

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