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Search Results for " pla2 "

Targets Recommended: Phospholipase

59

抑制剂 & 化合物

12

天然产物

29

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T15782	Lp-PLA2-IN-1 Lp-PLA2 inhibitor 1,Lp-PLA2 -IN-1	Phospholipase	Metabolism
	Lp-PLA2-IN-1 (Lp-PLA2 inhibitor 1) 是脂蛋白相关磷脂酶 A2(Lp-PLA2) 抑制剂。它有潜力用于动脉粥样硬化、阿尔茨海默氏病的研究。
T11874	Lp-PLA2-IN-3	Phospholipase	Metabolism
	Lp-PLA2-IN-3 是一种强效且具有口服生物活性的脂蛋白相关磷脂酶 A2（Lp-PLA2）抑制剂，对重组人 Lp-PLA2 具有抑制作用，IC50 值为 14 nM。
T11873	Lp-PLA2-IN-2	Phospholipase	Metabolism
	Lp-PLA2-IN-2 is a selective and potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2.
T63344	Lp-PLA2-IN-4
	Lp-PLA2-IN-4 是有效的脂蛋白相关磷脂酶 A2 (Lp-PLA2) 抑制剂。其中 Lp-PLA2 曾经被称作血小板活化因子乙酰水解酶 (PAF-AH)，是参与脂蛋白脂质或磷脂水解的磷脂酶 A2。Lp-PLA2-IN-4 具有潜力进行 Lp-PLA2 活性相关的疾病的研究，如阿尔茨海默病、动脉粥样硬化。
T79073	Lp-PLA2-IN-13	Phospholipase	Metabolism
	Lp-PLA2-IN-13（compound 15）是一种高效Lp-PLA2抑制剂，具备研究神经退行性疾病相关疾病的潜力。
T79076	Lp-PLA2-IN-16	Phospholipase	Metabolism
	Lp-PLA2-IN-16 (example 1) 为Lp-PLA2 (脂蛋白相关磷脂酶A2) 的一种抑制剂，主要在阿尔茨海默病等相关研究中应用。
T63633	Lp-PLA2-IN-6
	Lp-PLA2-IN-6 是四环嘧啶酮化合物，是 Lp-PLA2 的有效抑制剂，能够作用于 rhLp-PLA2 (pIC50: 10.0)。Lp-PLA2-IN-6 对神经退行性疾病表现出研究潜力。
T79010	Lp-PLA2-IN-12	Phospholipase	Metabolism
	Lp-PLA2-IN-12（compound 19）为一种Lp-PLA2抑制剂，主要应用于神经退行性疾病（如AD、青光眼、AMD）及心血管疾病（诸如动脉粥样硬化）的研究。
T62947	Lp-PLA2-IN-11
	Lp-PLA2-IN-11 是一种有效的脂蛋白相关磷脂酶 A2 (Lp-PLA2) 抑制剂。其中 Lp-PLA2 曾被称为血小板活化因子乙酰水解酶 (PAF-AH)，是一种参与脂蛋白脂质或磷脂水解的磷脂酶 A2。Lp-PLA2-IN-11 具有潜力进行与 Lp-PLA2 活性相关的疾病（如动脉粥样硬化、阿尔茨海默病）的研究。
T63345	Lp-PLA2-IN-5
	Lp-PLA2-IN-5 是有效的脂蛋白相关磷脂酶 A2 (Lp-PLA2) 抑制剂。其中 Lp-PLA2 曾经被称作血小板活化因子乙酰水解酶 (PAF-AH)，是参与脂蛋白脂质或磷脂水解的磷脂酶 A2。Lp-PLA2-IN-5 具有潜力进行 Lp-PLA2 活性相关的疾病的研究，如阿尔茨海默病、动脉粥样硬化。
T79074	Lp-PLA2-IN-14	Phospholipase	Metabolism
	Lp-PLA2-IN-14（Compound 19）是一种选择性的Lp-PLA2抑制剂，其对rhLp-PLA2表现出较高亲和力，pIC50值达到8.4。该化合物主要适用于对抗与神经退行性疾病相关的研究，包括阿尔茨海默病（AD）、青光眼、年龄相关性黄斑变性（AMD），以及心血管疾病如动脉粥样硬化等。
T63931	Lp-PLA2-IN-9
	Lp-PLA2-IN-9 (compound 17) 是一种四环嘧啶酮化合物，一种有效的Lp-PLA2抑制剂，能够作用于 rhLp-PLA2 (pIC50: 10.1)。Lp-PLA2-IN-9 对神经退行性疾病表现出研究潜力。
T79075	Lp-PLA2-IN-15	Phospholipase	Metabolism
	Lp-PLA2-IN-15 (example 2) 为一脂蛋白相关磷脂酶 A2 (Lp-PLA 2) 抑制剂，适用于阿尔茨海默病研究。
T63192	Lp-PLA2-IN-10
	Lp-PLA2-IN-10 是一种有效的脂蛋白相关磷脂酶 A2 (Lp-PLA2) 抑制剂。Lp-PLA2-IN-10 能够用于神经退行性相关疾病的研究，如阿尔茨海默病(AD)、青光眼、年龄相关的黄斑变性 (AMD)，或者包括动脉粥样硬化等心血管疾病。Lp-PLA2 曾经被称作血小板活化因子乙酰水解酶 (PAF-AH)，是一种参与脂蛋白脂质或磷脂水解的磷脂酶 A2。
T2044	Varespladib LY315920,伐瑞拉地,伐瑞拉迪	Phospholipase	Metabolism
	Varespladib (LY315920) 是选择性group IIA, secretory phospholipase A2(sPLA2)抑制剂，其IC50=9 nM。它对大鼠，兔，豚鼠和人等各种物种血清的sPLA2活性具有明显的抑制作用，IC50分别为 8.1 nM，5.0 nM，3.2 nM 和 6.2 nM。
T5580	1-Naphthaleneacetic acid potassium salt α-萘醋酸钾,α-Naphthaleneacetic acid,Potassium alpha-naphthylacetate,Potassium 1-Naphthaleneacetate,1-NAA Potassium Salt	Phospholipase	Metabolism
	1-Naphthaleneacetic acid potassium salt (1-NAA Potassium Salt) 是一种合成的植物生长素，能够促进植物生长，也是一种PLA2抑制剂，IC50=13.16 μM。
T12990	sPLA2-X Inhibitor 31	Others	Others
	sPLA2-X Inhibitor 31 is a selective inhibitor of secreted phospholipase A2 type X (sPLA2-X) (IC50s of 26 nM, 310 nM, and 2230 nM for sPLA2-X, sPLA2-IIa, and sPLA2-V, respectively).
T81115	sPLA2-IIA Inhibitor
	sPLA2-IIA Inhibitor 是 FLSYK 的环状五肽类似物，具有环2-Nal-Leu-Ser-2-Nal-Arg (c2) 结构，能够特异性结合 hGIIA（人类 IIA 磷脂酶 A2），有效抑制其酯键水解活性。该化合物作为酯酶超家族的一员，主要作用于甘油磷脂 sn-2 位置的酯键，从而阻断游离脂肪酸和花生四烯酸等物质的释放。
T82421	FAAH/cPLA2α-IN-1	Phospholipase	Metabolism
	FAAH/cPLA2α-IN-1为FAAH及cPLA2α的双重抑制剂，IC50值分别为32 nM和47 nM。
T27731	sPLA2 inhibitor 1 KH-064,KH 064,KH064,5-BPP acid
	KH064 is a sPLA2-IIA inhibitor of oral activity.
T6109	Darapladib 达拉地,SB-480848	Phospholipase	Metabolism
	Darapladib (SB-480848) 是脂蛋白相关磷脂酶A2 (Lp-PLA2) 抑制剂，IC50=0.25 nM。
T16751	Rilapladib SB 659032	Phospholipase	Metabolism
	Rilapladib (SB 659032) 是 Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) 的选择性抑制剂 (IC50 = 230 pM) 和血小板活化因子受体的拮抗剂。
TP1299L1	Melittin Acetate Melittin Acetate(20449-79-0 Free base),Forapin Acetate	Phospholipase	Metabolism
	Melittin Acetate (Forapin Acetate) 是一种PLA2激活剂。Melittin Acetate 低分子量 PLA2 的活性具有刺激，而不会增加高分子量 PLA2 的活性。
TP1299	Melittin 蜂毒素,蜂毒肽	Phospholipase	Metabolism
	Melittin 是 PLA2激活剂，能够刺激低分子量 PLA2的活性，而不刺激高分子量 PLA2的活性。
TP1299L	Melittin TFA(20449-79-0(free base))	Phospholipase	Metabolism
	Melittin TFA(20449-79-0(free base)) 是一种含有 26 个氨基酸残基的小蛋白质，是蜂毒的主要毒性成分。它是一种 PLA2 活化剂，可刺激低分子量 PLA2 的活性，而不会增加高分子量 PLA2 的活性。
T60967	Atg4B-IN-2	Phospholipase; Autophagy	Autophagy; Metabolism
	Atg4B-IN-2 是一种具有有效性的选择性的Atg4B 抑制剂，具有抗癌活性，对 Atg4B 和 PLA2 的活性有抑制作用。Atg4B-IN-2 通过细胞自噬 (autophagy) 来抵抗抗去势抗性前列腺癌药物的抗癌活性。
T31204	Darapladib-impurity	Others	Others
	Darapladib-impurity 是 Darapladib 的杂质。Darapladib 对脂蛋白相关磷脂酶 A2 (Lp-PLA2)有抑制作用。
T5454	N-(p-amylcinnamoyl) Anthranilic Acid 2-(3-(4-戊基苯基)丙烯酰胺基)苯甲酸,ACA	Phospholipase; TRP/TRPV Channel	Membrane transporter/Ion channel; Metabolism
	N-(p-amylcinnamoyl) Anthranilic Acid (ACA) 是一种广谱磷脂酶 A2(PLA2) 抑制剂，也是TRP channel 的阻滞剂。ACA 也可逆的抑制钙离子激活氯通道 (calcium-activated chloride channels) ，在心律失常方面具有研究的潜力。
T38404	MJ33 lithium salt	ROS	Immunology/Inflammation
	MJ33 lithium salt 是 NADPH 氧化酶 2 型介导的 ROS 生成抑制剂，是一种氟化磷脂类似物，可抑制过氧化物还蛋白 6 （Prdx6）的磷脂酶 A2 （PLA2）活性，可用于研究急性肺损伤。
T21606L	Anti-Inflammatory Peptide 1 Acetate Anti-Inflammatory Peptide 1 Acetate(118850-70-8 Free base)	Phospholipase	Metabolism
	Anti-Inflammatory Peptide 1 Acetate 在体内具有有效的抗炎活性，是磷脂酶 A2 (PLA2) 的强抑制剂，其存在和活性增加会导致某些身体部位的炎症和疼痛。
T21907	PACOCF3 1,1,1-trifluoroheptadecan-2-one,Palmityltrifluoromethylketone	Phospholipase	Metabolism
	PACOCF3 (Palmityltrifluoromethylketone) (Palmityltrifluoromethylketone) 是一种钙非依赖性的磷脂酶 A2 (phospholipase A2) 抑制剂，IC50为 3.8 μM。PACOCF3 改变肾小管细胞中的 Ca2+信号传导。
T1666	Fludrocortisone acetate 9α-Fluorcortisol acetate,9α-Fludrocortisone acetate,醋酸氟氢可的松,9α-fluorocortisol acetate	Glucocorticoid Receptor; Autophagy	Autophagy; Endocrinology/Hormones
	Fludrocortisone acetate (9α-Fludrocortisone acetate) 是一种合成的盐皮质激素，可减少尿液中钠丢失量，也用于增加血压，有用于阿狄森氏病的研究潜力。
T21815	ONO-RS-082	Others	Others
	ONO-RS-082 是磷脂酶 A 抑制剂。它抑制PLA2的IC50值为1.0 μM，但即使浓度达到 100 μM 也不抑制 PLC。
T75741	Melittin TFA
	Melittin TFA 是一种PLA2激活剂，可刺激低分子量 PLA2的活性，而不会提高高分子量 PLA2的活性。
T69414	Edunol
	Edunol is a pterocarpan isolated from Harpalyce brasiliana. It has shown antimyotoxic, antiproteolytic and PLA2 inhibitor properties.
T60816	Protizinic acid
	Protizinic acid 抑制磷脂酶 A2 (PLA2)，IC50值为 210 μM。Protizinic acid 是具有抗炎和解热活性的，口服非甾体抗炎剂。
T75255L1	SB-435495 ditartrate
	SB-435495 ditartrate，一种口服有效的Lp-PLA2抑制剂，特点为高效、选择性、可逆且非共价，IC50值为0.06 nM。
T37580	Arachidonoyl thio-PC
	Arachidonoyl Thio-PC is a substrate for many phospholipase A2s (PLA2s) including sPLA2, cPLA2, and iPLA2. Cleavage of the sn-2 fatty acid by PLA2 results in generation of a free thiol which reacts with chromogenic reagents such as DTNB (Ellman's reagent) and DTP to allow quantitation of PLA2 activity. Isozyme-specific cPLA2 activity can be measured by excluding or inhibiting sPLA2 and iPLA2 activities in the assay.
T75255	SB-435495
	SB-435495 是一种有效的、选择性的、可逆的、非共价的、具有口服活性的 Lp-PLA2抑制剂，IC50为 0.06 nM。
T75255L	SB-435495 hydrochloride
	SB-435495 hydrochloride，一种有效的、选择性的、可逆性非共价口服Lp-PLA2抑制剂，IC50值为0.06 nM。
T68752	Manoalide
	Manoalide，一种类萜化合物，有效抑制磷脂酶A2（PLA2）和磷脂酶C（PLC），具有抗炎和抗菌活性。
T37244	Palmitoyl thio-PC
	Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity. Palmitoyl thio-PC is a chromogenic PLA2 substrate that contains a palmitoyl thioester at the sn-2 position of the glycerol backbone. Hydrolysis of the thioester by PLA2 yields a free thiol that reacts readily with DTNB (Ellman's reagent) giving a bright yellow product with an absorbance maximum at 412 nm. Palmitoyl thio-PC has...
T76182	Phospholipase A2
	PhospholipaseA2 (PLA2) 催化膜磷脂质在 sn-2 位置的水解作用，释放出花生四烯酸 (AA)。该酶为钙依赖型且热稳定，广泛应用于生化实验中。
T37182	AX 048
	The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes. AX 048 is a potent group IVA cPLA2 inhibitor that demonstrates 50% inhibition of the enzyme at a mole fraction (XI(50)) of 0.022. Pretreatment with AX 048 (ED50 = 1.2 mg/kg) dose-dependently reduces thermal hyperalgesia evoked by carrageenan injection of r...
T71220	Luffolide
	Luffolide is a minor metabolite of the sponge Luffariella sp. Luffolide has some of the anti-inflammatory properties of manoalide : this may help to define the chemical reaction between manoalide and phospholipase A2. The hydrolisis of phosphatidyl choline PLA2 is completely inhibitted by Luffolide.
T63421	GSK2647544
	GSK2647544 是一种口服具有活力的 Lp-PLA2 的选择性抑制剂，是一种主要由单核细胞衍生的巨噬细胞分泌的钙非依赖性磷脂酶 A2，表现出促炎效果。
T23102	OBAA	Others	Others
	OBAA 是一种有效的磷脂酶 A2 (PLA2) 抑制剂(IC50= 70 nM)，并且在布氏锥虫中阻断 Melittin 诱导的 Ca2+流入(IC50= 0.4 μM)。
T37556	CAY10502
	Phospholipase A2 (PLA2) catalyzes the hydrolysis of phospholipids at the sn-2 position leading to the production of lysophospholipids and free fatty acids. Calcium-dependent cytosolic PLA2 (cPLA2α) is a 85 kDa enzyme that plays a key role in the arachidonic cascade and the inflammatory response associated with this metabolic pathway. CAY10502 is a potent inhibitor of calcium-dependent cytosolic PLA2α (cPLA2α) with an IC50 value of 4.3 nM for the purified enzyme from human platelets. It inhibits ...
T37121	1,2-bis(heptanoylthio) Glycerophosphocholine
	Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH). Interaction of this compound with a PLA2 results in cleavage of the sn-2 fatty acid generating a free thiol on the lysophospholipid. This free thiol can be detected using chromogenic substrates such as DTNB (Ellman's reagent) and DTP.
T37331	Pyrrophenone
	The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid (AA) from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins (PGs) and leukotrienes (LTs). Pyrrophenone inhibits cPLA2α with an IC50 of 4.2 nM in enzyme assays and potently blocks the release of AA and the production of PGE2 and LTC4 in cells (IC50 = 24, 25, and 14 nM, respectively). Its action is reversible and selective, as py...

化合物

Cat.No: T15782

Synonym: Lp-PLA2 inhibitor 1,Lp-PLA2 -IN-1

Target: Phospholipase

Cat.No: T11874

Target: Phospholipase

Cat.No: T11873

Target: Phospholipase

Cat.No: T63344

Lp-PLA2-IN-13

Cat.No: T79073

Target: Phospholipase

Lp-PLA2-IN-16

Cat.No: T79076

Target: Phospholipase

Cat.No: T63633

Lp-PLA2-IN-12

Cat.No: T79010

Target: Phospholipase

Lp-PLA2-IN-11

Cat.No: T62947

Cat.No: T63345

Lp-PLA2-IN-14

Cat.No: T79074

Target: Phospholipase

Cat.No: T63931

Lp-PLA2-IN-15

Cat.No: T79075

Target: Phospholipase

Lp-PLA2-IN-10

Cat.No: T63192

Cat.No: T2044

Synonym: LY315920,伐瑞拉地,伐瑞拉迪

Target: Phospholipase

1-Naphthaleneacetic acid potassium salt

Cat.No: T5580

Synonym: α-萘醋酸钾,α-Naphthaleneacetic acid,Potassium alpha-naphthylacetate,Potassium 1-Naphthaleneacetate,1-NAA Potassium Salt

Target: Phospholipase

sPLA2-X Inhibitor 31

Cat.No: T12990

Target: Others

sPLA2-IIA Inhibitor

Cat.No: T81115

FAAH/cPLA2α-IN-1

Cat.No: T82421

Target: Phospholipase

sPLA2 inhibitor 1

Cat.No: T27731

Synonym: KH-064,KH 064,KH064,5-BPP acid

Cat.No: T6109

Synonym: 达拉地,SB-480848

Target: Phospholipase

Cat.No: T16751

Synonym: SB 659032

Target: Phospholipase

Melittin Acetate

Cat.No: TP1299L1

Synonym: Melittin Acetate(20449-79-0 Free base),Forapin Acetate

Target: Phospholipase

Cat.No: TP1299

Synonym: 蜂毒素,蜂毒肽

Target: Phospholipase

Melittin TFA(20449-79-0(free base))

Cat.No: TP1299L

Target: Phospholipase

Cat.No: T60967

Target: Phospholipase, Autophagy

Darapladib-impurity

Cat.No: T31204

Target: Others

N-(p-amylcinnamoyl) Anthranilic Acid

Cat.No: T5454

Synonym: 2-(3-(4-戊基苯基)丙烯酰胺基)苯甲酸,ACA

Target: Phospholipase, TRP/TRPV Channel

MJ33 lithium salt

Cat.No: T38404

Target: ROS

Anti-Inflammatory Peptide 1 Acetate

Cat.No: T21606L

Synonym: Anti-Inflammatory Peptide 1 Acetate(118850-70-8 Free base)

Target: Phospholipase

Cat.No: T21907

Synonym: 1,1,1-trifluoroheptadecan-2-one,Palmityltrifluoromethylketone

Target: Phospholipase

Fludrocortisone acetate

Cat.No: T1666

Synonym: 9α-Fluorcortisol acetate,9α-Fludrocortisone acetate,醋酸氟氢可的松,9α-fluorocortisol acetate

Target: Glucocorticoid Receptor, Autophagy

Cat.No: T21815

Target: Others

Cat.No: T75741

Cat.No: T69414

Protizinic acid

Cat.No: T60816

SB-435495 ditartrate

Cat.No: T75255L1

Arachidonoyl thio-PC

Cat.No: T37580

Cat.No: T75255

SB-435495 hydrochloride

Cat.No: T75255L

Cat.No: T68752

Palmitoyl thio-PC

Cat.No: T37244

Phospholipase A2

Cat.No: T76182

Cat.No: T37182

Cat.No: T71220

Cat.No: T63421

Cat.No: T23102

Target: Others

Cat.No: T37556

1,2-bis(heptanoylthio) Glycerophosphocholine

Cat.No: T37121

Cat.No: T37331

Cat. No.	Product Name	Target	Signaling Pathways
TMO2790	1-Naphthaleneacetic acid Transplantone,1-Naphthylacetic acid,α-Naphthaleneacetic acid,Phyomone,1-萘乙酸	Phospholipase	Metabolism
	1-Naphthaleneacetic acid (Transplantone) 是一种 PLA2抑制剂，IC50=13.16 μM。它也是一种合成的植物生长素，可以促进植物生长。
TN4893	Rapanone 拉帕酮,2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone,2,5-Dihydroxy-3-tridecylcyclohexa-2,5-diene-1,4-dione,酸藤子醌	Apoptosis; Phospholipase; Antibacterial; Parasite	Apoptosis; Metabolism; Microbiology/Virology
	Rapanone (2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone) 是一种具有广泛生物活性的天然苯醌，如抗肿瘤、抗氧化、抗炎、抗菌和抗寄生虫活性。它还是选择性人滑膜 PLA2抑制剂，IC50值为 2.6 μM。
T10017	1-Linoleoyl Glycerol Glycerol 1-monolinolate,Monolinolein,一亚油酸甘油酯,Glyceryl monolinoleate,1-Linoleoyl-rac-glycerol	Phospholipase	Metabolism
	1-Linoleoyl Glycerol (Monolinolein) 是脂肪酸甘油。
TN6993	Benzylideneacetone Benzalacetone	Phospholipase; Endogenous Metabolite	Metabolism
	Benzylideneacetone 是由昆虫致病细菌 Xenorhabdus nematophila 产生的单萜类化合物，是磷脂酶A2（PLA2）抑制剂，对类花生酸生物合成具有抑制作用，可增强小菜蛾木霉菌的杆状病毒致病性。
T4S0590	Columbin	Phospholipase; COX; Parasite	Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience
	Columbin 是有口服活性的二萜呋喃内酯，选择性抑制COX-1和COX-2，EC50值为 327 μM 和 53.1 μM，具有抗炎和抗锥虫体作用。
T36831	9-Oxononanoic Acid 9-ONA	Phospholipase; CPT	Metabolism
	9-Oxononanoic Acid是一种氧化脂肪酸，由亚油酸自氧化形成，它能提高磷脂酶 A2（PLA2）的活性，并增加离体人体血浆中血栓素 B2 的生成。9-Oxononanoic Acid 能减少肝脏新脂肪酸的合成，并提高大鼠肝脏肉碱棕榈酰转移酶（β-氧化的标志物）的活性。
TCS1554	trans-Benzylideneacetone 反式苯亚甲基丙酮,Acetocinnamone,亚苄基丙酮	Phospholipase	Metabolism
	trans-Benzylideneacetone (Acetocinnamone) 是一种革兰氏阴性致病性线虫细菌嗜线虫(Xenorhabdus nematophila) 的代谢产物，是一种针对磷脂酶 A2 (PLA2) 的酶抑制剂，也是一种免疫抑制剂。
T2907	Tanshinone I 丹参酮I,Tanshinone A	Phospholipase	Metabolism
	Tanshinone I (Tanshinone A) 是IIA 型人重组sPLA2(IC50=11 μM)和兔重组cPLA2(IC50=82 μM)抑制剂。
T21893	Luffariellolide
	Luffariellolide 是人滑膜蛋白磷脂酶A2 (HSF-PLA2) 抑制剂 (IC50=5 μM)。Luffariellolide (ED50=50 μg/耳)可有效抑制佛波酯 (PMA) 引起的耳水肿。
TN5288	Ergosterol peroxide glucoside 过氧化麦角甾醇葡萄糖苷,Ergosterol peroxide 3-O-β-D-glucopyranoside
	Ergosterol peroxide exhibits anti-cancer, amoebicidal, anticomplementary, antibacterial, antiviral, anti-oxdiant, and anti-melanogenic activities. Ergosterol peroxide could as an anti-atherosclerosis agent, it exhibits hACAT-1 and Lp-PLA2 inhibitory effec
TN5221	(-)-Variabilin
	Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (GPIIb-IIIa; αIIbβ3) and the vitronectin receptor αvβ3.Variabilin is also an antimicrobial furanosesterterpene. Variabilin is an inhibitor of human secretory and cytosolic phospholipase A2 (PLA2) activities that controls eicosanoid production in vitro and in vivo, inhibits neutrophil degranulation and superoxide generation in vitro a...
T83864	Plipastatin A1 SNA-60-367-3,Fengycin IX
	Plipastatin A1是一种在B. cereus中发现的脂肽类化合物，具有酶抑制活性和免疫抑制活性。它能抑制磷脂酶A2（PLA2）、PLC和PLD（IC50分别为2.9、1.3和1.4 µM）。Plipastatin A1（100 µg/ml）能抑制LPS诱导的B细胞爆发生成和Concanavalin A诱导的T细胞爆发生成。在体内，Plipastatin A1（0.1 mg/动物）能抑制小鼠的迟发型超敏反应。

天然产物

1-Naphthaleneacetic acid

Cat.No: TMO2790

Synonym: Transplantone,1-Naphthylacetic acid,α-Naphthaleneacetic acid,Phyomone,1-萘乙酸

Target: Phospholipase

Cat.No: TN4893

Synonym: 拉帕酮,2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone,2,5-Dihydroxy-3-tridecylcyclohexa-2,5-diene-1,4-dione,酸藤子醌

Target: Apoptosis, Phospholipase, Antibacterial, Parasite

1-Linoleoyl Glycerol

Cat.No: T10017

Synonym: Glycerol 1-monolinolate,Monolinolein,一亚油酸甘油酯,Glyceryl monolinoleate,1-Linoleoyl-rac-glycerol

Target: Phospholipase

Benzylideneacetone

Cat.No: TN6993

Synonym: Benzalacetone

Target: Phospholipase, Endogenous Metabolite

Cat.No: T4S0590

Target: Phospholipase, COX, Parasite

9-Oxononanoic Acid

Cat.No: T36831

Synonym: 9-ONA

Target: Phospholipase, CPT

trans-Benzylideneacetone

Cat.No: TCS1554

Synonym: 反式苯亚甲基丙酮,Acetocinnamone,亚苄基丙酮

Target: Phospholipase

Cat.No: T2907

Synonym: 丹参酮I,Tanshinone A

Target: Phospholipase

Luffariellolide

Cat.No: T21893

Ergosterol peroxide glucoside

Cat.No: TN5288

Synonym: 过氧化麦角甾醇葡萄糖苷,Ergosterol peroxide 3-O-β-D-glucopyranoside

Cat.No: TN5221

Cat.No: T83864

Synonym: SNA-60-367-3,Fengycin IX

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01881	Lp-PLA2/PLA2G7 Protein, Human, Recombinant (His) LP-PLA2,PAFAD,phospholipase A2 gr...	Human	HEK293 Cells
	Lp-PLA2/PLA2G7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is Q13093-1.
TMPK-00028	PLA2G1B Protein, Human, Recombinant (hFc) PLA2AMGC119834,Phospholipase A2,<...	Human	HEK293 Cells
	PLA2G1B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 40.9 kDa and the accession number is P04054.
TMPK-00027	PLA2G1B Protein, Mouse, Recombinant (hFc) Phospholipase A2,PLA2,PLA	Mouse	HEK293 Cells
	PLA2G1B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 40.9 kDa and the accession number is Q9Z0Y2.
TMPY-01689	PLA2G1B Protein, Human, Recombinant (His) PLA2,PPLA2,phospholipase...	Human	HEK293 Cells
	PLA2G1B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is P04054.
TMPY-04912	PLA2G2A Protein, Mouse, Recombinant (His) Pla2,sPLA2,sPla...	Mouse	P. pastoris (Yeast)
	PLA2G2A Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 15.3 kDa and the accession number is P31482.
TMPJ-00553	Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His) PAF Acetylhydrolase,LDL-Associated Phospholipase A2...	Human	HEK293 Cells
	Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive products. PAFAH is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. PAFAH has been implicated in the development of atherosclerosis and has also been identified as a marker for cardiac disease. PAFAH might have a major physiologic effect in the presen...
TMPY-01705	PLA2G2A Protein, Human, Recombinant (His) PLAS1,phospholipase A2, group IIA (pla...	Human	HEK293 Cells
	PLA2G2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.4 kDa and the accession number is A0A024RA96.
TMPY-04692	Lp-PLA2/PLA2G7 Protein, Mouse, Recombinant (His) R75400,phospholipase A2 group VII	Mouse	HEK293 Cells
	Lp-PLA2/PLA2G7 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.3 kDa and the accession number is Q60963.
TMPY-04016	PLA2G2D Protein, Human, Recombinant (hFc) sPLA2-IID,PLA2IID,sP...	Human	HEK293 Cells
	PLA2G2D Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.5 kDa and the accession number is Q9UNK4.
TMPY-02181	PLA2G12B Protein, Mouse, Recombinant (His) Fksg71,2010002E04Rik,Pla2	Mouse	HEK293 Cells
	Group XIIB secretory phospholipase A2-like protein, also known as Group XIII secretory phospholipase A2-like protein, GXIII sPLA2-like, sPLA2-GXIIB, GXIIB, PLA2G13 and PLA2G12B, is a secreted protein that belongs to the phospholipase A2 family. PLA2G12B / PLA2G13 is strongly expressed in liver, small intestine and kidney. Mammalian secretory phospholipase A2s ( sPLA2s ) form a family of structurally related enzymes that are involved in a variety of physiological and pathological processes via th...
TMPY-02162	Phospholipase A2 IIE/PLA2G2E Protein, Mouse, Recombinant (His) phospholipase A2, group IIE	Mouse	HEK293 Cells
	Group IIE secretory phospholipase A2, also known as GIIE sPLA2, sPLA2-IIE, Phosphatidylcholine 2-acylhydrolase 2E and PLA2G2E is a secreted protein that belongs to the phospholipase A2 family. Mammalian secretory phospholipase A2s (sPLA2s) form a family of structurally related enzymes that are involved in a variety of physiological and pathological processes via the release of arachidonic acid from membrane phospholipids or the binding to specific membrane receptors. Phospholipases A2 / PLA2 are...
TMPH-00497	PLA2G15 Protein, Canine, Recombinant (His & Myc)	Canine	Baculovirus Insect Cells
	PLA2G15 Protein, Canine, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q6XPZ3.
TMPY-06121	PLA2G15 Protein, Chinese hamster, Recombinant (His) phospholipase A2, group XV	Chinese hamster	CHO Cells
	PLA2G15 Protein, Chinese hamster, Recombinant (His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 45 kDa and the accession number is G3HKV9-1.
TMPH-02071	PLA2R1 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus Insect Cells
	PLA2R1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPH-02692	PLA2G15 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	PLA2G15 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 50.5 kDa and the accession number is Q8VEB4.
TMPH-01850	PNPLA2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	PNPLA2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 71.3 kDa and the accession number is Q96AD5.
TMPH-02556	PLA2G5 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	PLA2G5 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 29.8 kDa and the accession number is P97391.
TMPH-02070	PLA2R1 Protein, Human, Recombinant (His)	Human	E. coli
	PLA2R1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-01010	PLA2G16 Protein, Human, Recombinant (His) Renal Carcinoma Antigen NY-REN-65,HRAS-Like Suppressor 1,HRS...	Human	E. coli
	Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models.
TMPH-02690	PLA2G10 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatidylcholines and phosphatidylglycerols over phosphatidylethanolamines. Preferentially releases sn-2 omega-6 and omega-3 polyunsaturated fatty acyl (PUFA) chains over saturated fatty acyls. Contributes to phospholipid remodeling of very low-density lipoprotein (VLDL), low-density li...
TMPY-02132	LYPLA2 Protein, Human, Recombinant (His) APT-2,lysophospholipase II,DJ886K2.4,APT	Human	E. coli
	Lysophospholipase II (LYPLA2, LPL-II, or LysoPLA II), also known as Acyl-protein thioesterase 2 (APT-2), belongs to the AB hydrolase 2 family. This enzyme has lysophospholipase activity and may hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Acyl-protein thioesterase 1 (APT-1) and Acyl-protein thioesterase 2 (APT-2) are cytosolic lysophospholipids hydrolyzing enzymes. The serum activity of APT-1 may play an important role in the dete...
TMPH-03309	PLA2G10 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	PLA2G10 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.4 kDa and the accession number is Q9QZT3.
TMPH-03255	PLA2G5 Protein, Rat, Recombinant (His & SUMO)	Rat	E. coli
	PLA2G5 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 29.8 kDa and the accession number is P51433.
TMPY-01911	PLA2G1B Protein, Mouse, Recombinant (His) Pla2a,sPLA2IB,phospholip...	Mouse	HEK293 Cells
	PLA2G1B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.3 kDa and the accession number is Q9Z0Y2.
TMPY-05255	PLA2G2D Protein, Mouse, Recombinant (hFc) mGIID,Splash,phospholipase A2, group IID	Mouse	HEK293 Cells
	PLA2G2D Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is Q3TYT9.
TMPH-02691	PLA2G12A Protein, Mouse, Recombinant (His & Myc)	Mouse	Baculovirus Insect Cells
	PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine. PLA2G12A Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 22.6 kDa and the accession number is Q9EPR2.
TMPH-00066	Phospholipase A2 Protein, Apis mellifera, Recombinant (His)	Apis mellifera	E. coli
	PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
TMPY-02805	GNGT1 Protein, Human, Recombinant (His) guanine nucleotide binding protein (G protein), γ transducin...	Human	E. coli
	GNGT1 is a subunit of transducin. Heterotrimeric G proteins consist of alpha, beta, and gamma subunits. They are membrane-bound GTPases that are linked to 7-TM receptors. They function as signal transducers for the 7-transmembrane-helix G protein-coupled receptors. They are involved as a modulator or transducer in various transmembrane signaling systems. G proteins are bound to GDP in the 'off' state. GNGT1 is the gamma subunit of transducin. Ligand-receptor binding results in detachment of the ...
TMPY-02802	GNG13 Protein, Human, Recombinant (His) G(gamma)13,h2-35,G(γ)13,guanine nucleotide binding ...	Human	E. coli
	GNG13 is a subunit of heterotrimeric G proteins which consist of alpha, beta, and gamma subunits. Heterotrimeric G proteins are membrane-bound GTPases that are linked to 7-TM receptors. They function as signal transducers for the 7-transmembrane-helix G protein-coupled receptors. They are involved as a modulator or transducer in various transmembrane signaling systems. Each G protein is composed of an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding...

重组蛋白

Lp-PLA2/PLA2G7 Protein, Human, Recombinant (His)

Cat.No: TMPY-01881

Species: Human

Expression System: HEK293 Cells

PLA2G1B Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00028

Species: Human

Expression System: HEK293 Cells

PLA2G1B Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00027

Species: Mouse

Expression System: HEK293 Cells

PLA2G1B Protein, Human, Recombinant (His)

Cat.No: TMPY-01689

Species: Human

Expression System: HEK293 Cells

PLA2G2A Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04912

Species: Mouse

Expression System: P. pastoris (Yeast)

Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His)

Cat.No: TMPJ-00553

Species: Human

Expression System: HEK293 Cells

PLA2G2A Protein, Human, Recombinant (His)

Cat.No: TMPY-01705

Species: Human

Expression System: HEK293 Cells

Lp-PLA2/PLA2G7 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04692

Species: Mouse

Expression System: HEK293 Cells

PLA2G2D Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04016

Species: Human

Expression System: HEK293 Cells

PLA2G12B Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02181

Species: Mouse

Expression System: HEK293 Cells

Phospholipase A2 IIE/PLA2G2E Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02162

Species: Mouse

Expression System: HEK293 Cells

PLA2G15 Protein, Canine, Recombinant (His & Myc)

Cat.No: TMPH-00497

Species: Canine

Expression System: Baculovirus Insect Cells

PLA2G15 Protein, Chinese hamster, Recombinant (His)

Cat.No: TMPY-06121

Species: Chinese hamster

Expression System: CHO Cells

PLA2R1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02071

Species: Human

Expression System: Baculovirus Insect Cells

PLA2G15 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02692

Species: Mouse

Expression System: E. coli

PNPLA2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01850

Species: Human

Expression System: E. coli

PLA2G5 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02556

Species: Mouse

Expression System: E. coli

PLA2R1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02070

Species: Human

Expression System: E. coli

PLA2G16 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01010

Species: Human

Expression System: E. coli

PLA2G10 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02690

Species: Mouse

Expression System: E. coli

LYPLA2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02132

Species: Human

Expression System: E. coli

PLA2G10 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03309

Species: Rat

Expression System: E. coli

PLA2G5 Protein, Rat, Recombinant (His & SUMO)

Cat.No: TMPH-03255

Species: Rat

Expression System: E. coli

PLA2G1B Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01911

Species: Mouse

Expression System: HEK293 Cells

PLA2G2D Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-05255

Species: Mouse

Expression System: HEK293 Cells

PLA2G12A Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02691

Species: Mouse

Expression System: Baculovirus Insect Cells

Phospholipase A2 Protein, Apis mellifera, Recombinant (His)

Cat.No: TMPH-00066

Species: Apis mellifera

Expression System: E. coli

GNGT1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02805

Species: Human

Expression System: E. coli

GNG13 Protein, Human, Recombinant (His)

Cat.No: TMPY-02802

Species: Human

Expression System: E. coli

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