92
11
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7125 |
4-Butylresorcinol
Butylresorcinol,4-正丁基间苯二酚,4-丁基间苯二酚 |
Tyrosinase | Proteases/Proteasome |
4-Butylresorcinol (Butylresorcinol) 是苯酚衍生物,可以抑制酪氨酸酶,其IC50=11.27 μM。 | |||
T0314 |
Hexylresorcinol
己雷锁辛,4-己基间苯二酚,4-Hexylresorcinol |
Apoptosis; Tyrosinase; Antibacterial; Parasite | Apoptosis; Microbiology/Virology; Proteases/Proteasome |
Hexylresorcinol (4-Hexylresorcinol) 是在植物中发现的一种天然产物,具有抗菌、驱虫、防腐和抗肿瘤活性。它是一种可逆、非竞争性的 α-葡萄糖苷酶抑制剂,有抗 DNA 氧化损伤的保护作用。它可诱导鳞癌细胞凋亡。 | |||
T21582L |
Acetyl Angiotensinogen (1-14), porcine Acetate
Acetyl Angiotensinogen (1-14), porcine Acetate(66641-26-7 Free base) |
Others | Others |
Acetyl Angiotensinogen (1-14), porcine Acetate 是一种肽,序列为 AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH。由血管紧张素原基因编码的蛋白质被称为前血管紧张素原或血管紧张素原前体。 | |||
T76341L |
[DPro10] Dynorphin A (1-11)acetate,porcine
[DPro10] Dynorphin A (1-11)acetate,porcine(94596-26-6 Free base) |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
[DPro10] Dynorphin A (1-11)acetate,porcine 是一种高效的 κ-阿片受体激动剂,其 Ki 值为 0.13 nM。[DPro10] Dynorphin A (1-11), porcine 是一种 N-烷基化衍生物,具有镇痛活性。 | |||
T66491 |
4-(1-Phenylethyl)resorcinol
4-(1-Phenylethyl)benzene-1,3-diol,Phenylethyl resorcinol |
Others | Others |
4-(1-Phenylethyl)resorcinol (4-(1-Phenylethyl)benzene-1,3-diol) 是一种亮肤剂,属于化妆品添加。它的作用是抑制黑色素的产生,减少黑斑、色素沉着和肤色不均的出现,提亮肤色减少皮肤暗沉。4-(1-Phenylethyl)resorcinol 在化妆品行业一般认为是安全的,在多个国家和地区广泛使用。 | |||
TP1880L1 |
PAMP-12 (human, porcine) acetate
PAMP-12 (human, porcine) acetate(196305-05-2 free base) |
Others | Others |
PAMP-12 (human, porcine) acetate (PAMP-12 (human, porcine) acetate (196305-05-2 free base)) 是 ir-PAMP 的主要成分,由 AM 前体加工而成,PAMP-20 也是如此,并且可能参与心血管控制。 | |||
TP1283L |
VIP(6-28)(human, rat, porcine, bovine) acetate
|
Others | Others |
VIP(6-28)(human, rat, porcine, bovine) acetate 是外源性血管活性肠肽 (VIP) 受体对颈上神经节 (SCG) 中 cAMP 作用的拮抗剂。 | |||
TP2026L |
GRP (porcine) acetate
GRP (porcine) acetate(74815-57-9 Free base) |
Others | Others |
GRP (porcine) acetate 是从猪胰腺中提取的胃泌素释放肽。 GRP (porcine) acetate 可能在猪胰腺内分泌和外分泌的副交感神经调节中起作用。 | |||
TP1380 |
Galanin (1-16), mouse, porcine, rat
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Galanin (1-16), mouse, porcine, rat 是一种有效的甘丙肽受体激动剂,Kd 为 3 nM。 | |||
T13865 |
Resorcinolnaphthalein
|
RAAS | Endocrinology/Hormones |
Resorcinolnaphthalein 是一种特异性的血管紧张素转换酶 2 激活剂,EC50=19.5 μM。Resorcinolnaphthalein 能够用于高血压和肾纤维化的研究 | |||
TP1425 |
Motilin (26-47), human, porcine
胃动素 (人类,猪) |
Motilin Receptor | GPCR/G Protein |
Motilin (26-47), human, porcine 是内源性 motilin 受体的激动剂,在中国仓鼠卵巢细胞中,Ki 值和EC50值分别为 2.3 和 0.3 nM。 | |||
TP2206 |
[Leu31,Pro34]-Neuropeptide Y (porcine)
LEU 31, PRO34]-神经肽Y(猪) |
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
[Leu31,Pro34]- Neuropeptide Y (porcine) 是神经肽 Y (NPY) 的一种类似物,是对NPY Y1受体有选择性的激动作用。它表现出抗焦虑作用。 | |||
TP1179L |
Porcine dynorphin A(1-13) acetate
Dynorphin A Porcine Fragment 1-13 acetate,Porcine dynorphin A(1-13) acetate(72957-38-1 free base) |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Porcine dynorphin A(1-13) acetate (Dynorphin A Porcine Fragment 1-13 acetate)(72957-38-1 free base) 是一种有效的内源性 κ opioid 受体激动剂,在生理浓度下具有镇痛作用。暴露于强啡肽 A (1-13) 会导致单个神经元中 [Ca2+]i 的急剧增加,类似于急性 NMDA 治疗所见的增加。 | |||
TD0092 |
Naphthoresorcinol
间萘二酚,1,3-二羟基萘,1,3-Dihydroxynaphthalene |
Others | Others |
Naphthoresorcinol (1,3-Dihydroxynaphthalene) 是一种荧光染料 (λex=330 nm, λem=380 nm),与 NPPD (一种示踪剂) 和浓 HCl 反应显示出红色。它也能够作为测定碳水化合物的背景电解质 (BGE) 。 | |||
TP1219 |
Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate
ANP (1-28), human, porcineANP(1-28) |
||
Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate 是颗粒鸟苷酸环化酶的刺激剂,已被发现通过增加环鸟苷单磷酸的合成来保护分离的心肌细胞免受复氧诱导的高收缩。Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate 也有助于在反复运动期间刺激脂解,并在运动期间控制脂解。 | |||
T9934 |
5-Methoxyresorcinol
Flamenol,夫拉美诺 |
Others | Others |
5-Methoxyresorcinol (Flamenol) 是一个化学中间体。 | |||
T15389L |
Glucagon (1-29), bovine, human, porcine hydrochloride
盐酸胰高血糖素,Porcine glucagon hydrochloride,Glucagon hydrochloride |
Glucocorticoid Receptor; Glucagon Receptor | Endocrinology/Hormones; GPCR/G Protein |
Glucagon (1-29), bovine, human, porcine hydrochloride 是一种由胰腺 α 细胞产生的多肽激素。它可激活 HNF4α 并促进 HNF4α 磷酸化,促进糖异生。 | |||
T21743L |
Beta-Lipotropin (1-10), porcine Acetate
Beta-Lipotropin (1-10), porcine Acetate(77875-68-4 Free base) |
Others | Others |
Beta-Lipotropin (1-10), porcine Acetate (Beta-Lipotropin ) 被发现在其 C 末端序列中包含这些肽的一级结构。 | |||
T38648L |
Cecropin P1, porcine acetate
|
Endogenous Metabolite | Metabolism |
Cecropin P1, porcine acetate 是一种在 Hyalophora cecropia 和猪肠道中发现的抗菌肽。 | |||
T37588L |
GIP (1-30) amide, porcine acetate
|
IGF-1R | Tyrosine Kinase/Adaptors |
GIP (1-30) amide, porcine acetate 是完全葡萄糖依赖性促胰岛素多肽 (GIP) 受体的激动剂。它可弱抑制胃酸分泌,强烈刺激胰岛素。 | |||
T40495 |
Elastase from porcine pancreas
弹性蛋白酶,EC 3.2.1.35 |
Others | Others |
Elastase from porcine pancreas 由 240 个氨基酸残基组成,是一种丝氨酸蛋白酶,可以水解蛋白质和多肽。它可诱发仓鼠气肿。 | |||
T83677 |
Neuropeptide Y (porcine, bovine) TFA
NPY (porcine, bovine) |
||
神经肽Y(Neuropeptide Y, NPY)是一种参与调节食欲、血管收缩、心脏收缩力和肠道分泌的神经肽,同时也是NPY受体Y1、Y2和Y5的激动剂。它在全身范围内表达。NPY能够在表达大鼠Y1或Y2以及表达大鼠Y5的HEK293细胞中选择性抑制由forskolin诱导的cAMP积累,而对表达大鼠Y4受体的L-M(TK-)细胞的影响较小(EC50分别为0.15、2.7、0.66和>1,000 nM)。在分离的豚鼠心脏模型中,NPY能够增加灌注压(EC30 = 1.3 nM)。神经内注射NPY(300 pmol/动物)能够在大鼠中增加食物摄取量。 | |||
T37601 |
GIP (1-30) amide, porcine TFA
|
||
GIP (1-30) amide, porcine TFA is a high-affinity full agonist of the glucose-dependent insulinotropic polypeptide (GIP) receptor, having a similar potency as the native GIP(1-42) [1]. Furthermore, GIP (1-30) amide, porcine displays weak inhibitory effects on gastric acid secretion while exhibiting potent insulin-stimulating properties. | |||
T80503 |
Proadrenomedullin (N-20) (bovine, porcine)
ProADM N20(bovine, porcine),PAMP-20(bovine, porcine) |
||
Proadrenomedullin (N-20) (bovine, porcine) 是一种来源于嗜铬细胞的、具有降压及抑制 catecholamine release 的非竞争性肽类。该化合物能显著抑制 PC12 嗜铬细胞瘤细胞的 catecholamine 分泌,显示出 350 nM 的 IC50 值。此外,Proadrenomedullin (N-20) (bovine, porcine) 作为 EC50 约为 270 nM 的阻断剂,能够有效抵抗烟碱能激动剂引起的 catecholamine release 脱敏现象和烟碱相关的信号通道 (22Na+摄取)。 | |||
T81681 |
Neuromedin U-25 (porcine)
|
||
Neuromedin U-25 (porcine) 是一类具有子宫刺激和升高血压作用的肽。 | |||
T76355 |
Neuropeptide Y (3-36) (porcine)
|
||
Neuropeptide Y (3-36) (porcine) 是一种针对 Y2 亚型的 NPY 受体的激动剂,同时也通过一种尚未明确的受体来调控大鼠的摄食行为。 | |||
T75973 |
Secretin, porcine TFA
|
||
Porcine secretin TFA (Porcine secretin TFA) 是一种含有27个氨基酸的多肽,能够影响胰腺腺泡细胞和导管上皮细胞,促进碳酸氢盐丰富的流体生成。 | |||
T80145 |
Galanin-Like Peptide (porcine)
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Galanin-Like Peptide (porcine) 是由60个氨基酸组成的神经肽,原始分离自猪下丘脑。这一肽类对GALR2受体表现出高度亲和力(IC50为0.24 nM),而对GALR1受体则表现出较低的亲和性(IC50为4.3 nM)。 | |||
TP1179 |
Porcine dynorphin A(1-13)
Dynorphin A Porcine Fragment 1-13 |
||
Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acut | |||
T80881 |
Valosin (porcine)
|
||
Valosin (porcine)是一种含有25个氨基酸的生物活性肽,最近从猪肠中分离得到,主要用于消化系统研究。 | |||
T40364 |
Proinsulin C-Peptide (31-63), porcine
|
||
Proinsulin C-Peptide (31-63), porcine, is a peptide derived from the cleavage of porcine proinsulin, specifically spanning the 31st to 63rd amino acid residues. | |||
TP1048 |
Secretin, porcine
Porcine secretin acetate |
||
Secretin, porcine (Porcine secretin acetate) is a 27-amino acid peptide, acting on pancreatic acinar cells and ductal epithelial cells stimulating the production of bicarbonate rich fluid. Secretin porcine stimulates pancreatic and gastric secretions to a | |||
T82520 |
Dynorphin (2-17) (porcine)
|
||
Dynorphin (2-17) (porcine),一种源自Prodynorphin的肽类化合物,具有缓解Morphine依赖性戒断症状的功能。 | |||
T76337 |
[DAla2, DArg6] Dynorphin A, (1-13) (porcine)
|
||
[DAla2, DArg6] Dynorphin A, (1-13) (porcine) (DADAD) 是猪脑垂体提取物中发现的阿片肽(dynorphinl-13, DYN)的一个衍生物。该化合物对GPI和MVD的外周阿片受体有高效力,但在体内易被快速分解。与原始肽相比,[DAla2, DArg6] Dynorphin A, (1-13) (porcine) 更具酶解稳定性,能有效抵抗酶的裂解作用。 | |||
T36427 |
PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)
|
PACAP | GPCR/G Protein |
Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells. It binds to PACAP receptors on SH-SY5Y and SK-N-MC human neuroblastoma and T47D human breast cancer cells (IC50s = 24.5, 106, and 105 nM, respectively) and inhibits cAMP accumulation induced by PACAP (1-38) (Kis = 457, 102, and 283 nM, respectively, in SH-SY5Y, ... | |||
T83550 |
(Asp28)-Glucagon (1-29) (human, rat, porcine)
|
||
'(Asp28)-Glucagon (1-29) (human, rat, porcine)' 为胰高血糖素的一种改良型结构,在第28位氨基酸残基上天冬氨酸(Asp)替换原有残基,显著提高了该化合物在生理pH条件下的溶解性,且保持了与天然胰高血糖素相同的生物活性。 | |||
TP1047 |
Secretin, porcine TFA (17034-34-3 free base)
Porcine secretin TFA,Secretin, porcine TFA |
||
Secretin, porcine TFA (Porcine secretin TFA) is a 27-amino acid peptide, acting on pancreatic acinar cells and ductal epithelial cells stimulating the production of bicarbonate rich fluid.Secretin porcine stimulates pancreatic and gastric secretions to ai | |||
T36925 |
Neuromedin C (porcine)
|
||
Neuromedin C (porcine) 是一种铃蟾肽样神经肽,可从猪脊髓中获得。Neuromedin C (porcine) 对大鼠子宫具有收缩活性。Neuromedin C (porcine) 有研究神经系统相关疾病的潜力。 | |||
TNU1454 |
2-Amino-1,3-benzenediol; 2-Aminoresorcinol
|
||
Fine Chemicals; Intermediates and Building Blocks - Nucleophiles | |||
T66292 |
4-Chlororesorcinol
|
||
4-Chlororesorcinol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66292,CAS号为 95-88-5。 | |||
T124708 | 4,5-Dimethyl-1,3-benzenediol; o-Xylorcinol | ||
4,5-Dimethyl-1,3-benzenediol; o-Xylorcinol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124708,CAS号为 527-55-9。 | |||
T41065 |
Atrial natriuretic factor (1-28) (human, porcine)
Atrial natriuretic factor (1-28) (human, porcine),Atrial natriuretic peptide (1-28) |
||
Atrial natriuretic factor (1-28) from both human and porcine sources is a powerful suppressor of pro-opiomelanocortin (POMC) mRNA, while it only has a modest inhibition effect on βEP-LI release. | |||
T81489 |
PHI-27 (porcine)
|
||
PHI-27 (porcine)是由27个氨基酸组成的肽类化合物,主要用于探索肽激素及其他活性肽。 | |||
T75773 |
Peptide YY (PYY) (3-36), porcine TFA
|
||
Peptide YY (PYY) (3-36), porcine TFA,为一种肠胃激素肽,作用于Y2受体,具有降低食欲的功能。 | |||
TP1317 |
Galanin (1-16), mouse, porcine, rat TFA
|
||
Galanin (1-16), mouse, porcine, rat is an agonist of the hippocampal galanin receptor, with a Kd of 3 nM. Galanin (1-16), mouse, porcine, rat shows high biological activity on locus coeruleus neurons. | |||
TP2243 |
Dynorphin (2-17), amide, porcine
|
Others | Others |
Dynorphins are a class of opioid peptides that arise from the precursor protein prodynorphin. When prodynorphin is cleaved during processing by proprotein convertase 2 (PC2), multiple active peptides are released: dynorphin A, dynorphin B, and α/β-neo-end | |||
T76356 |
Neuropeptide Y (2-36) (porcine)
|
||
Neuropeptide Y (2-36) (porcine) 是一种具有 97.14% 与大鼠/人类同源性的猪源性神经肽。作为一种大鼠神经肽受体激动剂,其对Y5、Y2和Y1受体的EC50值为1.2, 1.6 和 3.4 nM,能显著增加食物摄入量,适用于肥胖和饮食失调研究。 | |||
T76357 |
Neuropeptide Y (18-36) (porcine)
|
||
Neuropeptide Y (18-36) (porcine) 是一种与Neuropeptide Y(NPY)心脏受体进行竞争性拮抗的化合物。该化合物通过浓度依赖的方式,抑制I-NPY与心室膜的结合,具有IC50值158 nM和Ki值140 nM。Neuropeptide Y (18-36) (porcine) 主要用于充血性心力衰竭的研究。 | |||
TP1961L |
PR 39 (porcine) acetate
|
Proteasome; Antibacterial | Microbiology/Virology; Proteases/Proteasome; Ubiquitination |
PR 39 (porcine) acetate 是一种非竞争性、可逆的变构蛋白酶体抑制剂。 它可逆地与蛋白酶体的 α7 亚基结合,并通过泛素-蛋白酶体途径阻断 NF-κB 抑制剂 IκBα 的降解。 | |||
T38048 |
Globotetraosylceramides (porcine RBC)
|
||
Globotetraosylceramides are bioactive neutral glycosphingolipids. They are the major glycolipids in human erythrocytes. They act as receptors for the Shiga toxins Stx1, Stx2, and Stx2e, the cytotoxic protein pierisin-1, and parvovirus B19. Globotetraosylceramides increase the expression of proteins responsible for enamel deposition, including ameloblastin, amelogenin, and enamelin, in dental epithelial cells and activate the ERK and p38 MAPK signaling pathways. Levels of globotetraosylceramides ... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3748 |
orcinol
5-Methylresorcinol,苔黑素、苔黑酚、地衣酚,3,5-Dihydroxytoluene,3,5-二羟基甲苯,地衣酚,5-Methylresorcin,3,5-ToluenediolOrcin,5-Methyl-1,3-benzenediol,Orcin |
Others | Others |
orcinol (5-Methylresorcin) 可用于生物染料和蛋白质组学研究。 | |||
T2771 |
Orcinol glucoside
Sakakin,苔黑酚葡萄糖苷 |
Antioxidant | oxidation-reduction |
Orcinol glucoside (Sakakin) 是一种提取自莪术中的活性成分,具有抗抑郁活性。它能诱导 MSC 转化为成骨细胞,并通过 Wnt/β-catenin 信号通路阻断脂肪形成。 | |||
TN6488 |
Orcinol 1-O-beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside
|
||
Orcinol 1-O-beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside has antioxidative activity. | |||
TN3112 |
5-Heneicosylresorcinol
|
NADPH-oxidase; Antifection | Immunology/Inflammation; Microbiology/Virology |
5-Heneicosylresorcinol 对 RBL-2H3 细胞中 β-己糖胺酶的释放具有抑制作用,它还可以防止 3T3-L1 细胞中甘油三酯的积累。它对红线虫、秀丽隐杆线虫和松材线虫具有杀线虫活性,ED50 值分别为 80、30 和 180 ug/mL。 | |||
T60859 |
5-Pentadecylresorcinol
|
||
5-Pentadecylresorcinol (Adipostatin A) 对埃及伊蚊具有良好的杀幼虫活性,它是甘油3-磷酸脱氢酶 (GPDH) 抑制剂,IC50值为 4.1 μM。 | |||
T5S1963 |
Orcinol gentiobioside
Anacardoside,苔黑酚龙胆二糖苷 |
Others | Others |
Orcinol gentiobioside 是一种提取自C. breviscapa 根茎块中的天然产物。 | |||
TN5637 |
5-(Z-Heptadec-8-enyl)resorcinol
5-(8-Heptadecenyl)-1,3-benzenediol |
||
5-(Z-Heptadec-8-enyl)resorcinol是一种天然产物,属于紫金牛科紫金牛属,其产品编号为 TN5637,CAS号为 52483-19-9。5-(Z-Heptadec-8-enyl)resorcinol可用作对照参考。 | |||
TN5640 |
5-Pentacosylresorcinol
5-Pentacosyl-1,3-benzenediol,5-二十五烷基间苯二酚 |
||
5-Pentacosylresorcinol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5640,CAS号为 70110-61-1。 | |||
T40368 | 4-Ethylresorcinol | ||
4-Ethylresorcinol, a derivative of resorcinol, functions as a tyrosinase substrate, possesses hypopigmentary effects, attenuates mRNA and protein expression of tyrosinase-related protein-2 (TRP-2), and exhibits antioxidative properties through inhibition of lipid peroxidation. | |||
TN3113 |
5-Heptadecylresorcinol
芒果 |
Others | Others |
5-Heptadecylresorcinol has strong inhibitory property against the growth of PC3 cells. | |||
TN3129 |
5-Nonadecylresorcinol
|
Others | Others |
5-Nonadecylresorcinol shows inhibitory effects on the release of β-hexosaminidase from RBL-2H3 cells. |