首页工具

登录

搜索结果

Search Results for " irap "

Targets Recommended: Apoptosis Others PARP

27

抑制剂 & 化合物

3

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T3231	Niraparib 尼拉帕尼,MK-4827	Apoptosis; Others; PARP	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	Niraparib (MK-4827) 是一种 PARP 抑制剂，可以抑制 PARP1 和 PARP2 (IC50=3.8/2.1 nM)，具有选择性。Niraparib 具有抗肿瘤活性，可以抑制 DNA 损伤修复、诱导细胞凋亡。
T4434	Tirapazamine Tirazone,Win59075,SR4233,替拉扎明,SR259075	Others	Others
	Tirapazamine (Win59075) 是抗癌剂，对实体瘤中的缺氧细胞具有选择性细胞毒性，促使 DNA 中的单链和双链断裂，碱基损伤和细胞死亡。
T3353	Niraparib hydrochloride 尼拉帕利盐酸盐,MK-4827 hydrochloride,MK-4827 (hydrochloride)	Apoptosis; Others; PARP	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	Niraparib hydrochloride (MK-4827 hydrochloride) 是一种具有口服活性的PARP1和PARP2抑制剂，IC50值分别为 3.8 nM 和 2.1 nM。它抑制 DNA 损伤修复，诱导凋亡并具有抗肿瘤活性。
T6892	Niraparib tosylate 尼拉帕利,MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate,尼拉帕尼对苯甲磺酸盐	Apoptosis; PARP	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Niraparib tosylate (MK-4827(tosylate)) 是一种高效的，具有生物口服利用度的PARP1和PARP2抑制剂，IC50分别为 3.8 和 2.1 nM。它抑制 DNA 损伤修复，诱导凋亡并具有抗肿瘤活性。
T1595	Nevirapine NSC 641530,奈韦拉平,BI-RG 587,奈伟拉平,NVP	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Nevirapine (NVP) 是一种 HIV-1逆转录酶非核苷抑制剂，Ki 值为 270 μM，可用于研究 HIV/AIDS。
T10820L1	Ciraparantag acetate Ciraparantag acetate(1438492-26-2 Free base)	Others	Others
	Ciraparantag acetate 是一种抗凝逆转剂，是一种小分子，专门设计用于通过电荷-电荷相互作用与普通肝素和低分子量肝素非共价结合。它显示出与直接口服抗凝剂 (DOAC) 相似的结合特性。
T12064	Niraparib (R-enantiomer) MK 4827 (R-enantiomer),Niraparib R-enantiomer	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Niraparib R-enantiomer (MK 4827 R-enantiomer) 是一种 PARP1抑制剂，IC50为 2.4 nM。
T9497	Niraparib tosylate monohyrate	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Niraparib tosylate monohyrate 也称为 MK-4827，是一种聚 (ADP-核糖) 聚合酶 (PARP) 抑制剂，具有潜在的抗肿瘤活性。 MK4827 抑制 PARP 活性，增强 DNA 链断裂的积累，促进基因组不稳定性和细胞凋亡。 PARP 蛋白家族通过碱基切除修复 (BER) 途径检测和修复单链 DNA 断裂。
T71517	Nevirapine quinone methide
	Nevirapine quinone methide is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.
T63425	Spirapril hydrochloride
	Spirapril (SCH 33844) hydrochloride 是血管紧张素转换酶 (ACE) 的有效抑制剂，是一种口服具有活力的螺普利拉前药。Spirapril hydrochloride 能够竞争性地与 ACE 结合，阻断血管紧张素I 向血管紧张素 II 的转化，表现出降压活性。Spirapril hydrochloride 能够用于研究高血压、充血性心力衰竭。
T68214	Famiraprinium chloride
	Famiraprinium chloride is a competitive antagonist at the GABA receptor site.
T69796	Nevirapine hemihydrate
	Nevirapine hemihydrate is a non-nucleoside reverse transcriptase inhibitor (NNRTI) studied for potential treatment of HIV-1 infection and AIDS.
T34696	Spirapril HCl BRN4277924,BRN-4277924,BRN 4277924,Spiraprilum,Spirapril,Espirapril
	Spiropril is an ACE inhibitor antihypertensive drug, which belongs to the bicarboxyl group of ACE inhibitors and is used in the treatment of hypertension.
T24820	Spiraprilat Spiraprilate,SCH-33861,SCH 33861,SCH33861
	Spiraprilat is an ACE inhibitor. It also is an active metabolite of spirapril.
T70794	Nevirapine dimer
	Nevirapine dimer is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
T10820	Ciraparantag PER977	Others	Others
	Ciraparantag is an inhibitor of thrombin and factor Xa. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including unfractionated heparin, low-molecular-weight heparin, and certain direct oral anticoagulants.
T71524	Famiraprinium
	Famiraprinium is a competitive antagonist at the GABA receptor site.
T12229	Niraparib metabolite M1 尼拉帕尼代谢物,M1 metabolite of niraparib,Niraparib carboxylic acid metabolite M1	Others	Others
	Niraparib metabolite M1 is niraparib metabolite, niraparib is a novel poly(ADP-Ribose) polymerase (PARP) inhibitor.
T10820L	Ciraparantag TFA PER977 TFA	Others	Others
	Ciraparantag TFA is an inhibitor of thrombin and factor Xa. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including unfractionated heparin, low-molecular-weight heparin, and certain direct oral anticoagulants.
T74717	12-Hydroxynevirapine
	12-Hydroxyvirapine (12-hydroxy-NVP; 12-OH-NVP) 是奈韦拉平的主要氧化代谢产物。奈韦拉平是一种非核苷类逆转录酶抑制剂，适用于 HIV-1感染，会引起特异性肝毒性和轻度至重度皮疹。12-Hydroxynevirapine 是一种非反应性代谢物，可被肝脏和皮肤中的磺基转移酶 (SULT) 生物激活，产生活性物质 12-Sulphoxy-nevirapine。
T74084	28-Epirapamycin
	28-Epirapamycin 是 Rapamycin 的一种杂质。Rapamycin 是一种高效特异的mTOR 抑制剂，在 HEK293 细胞中的 IC50为 0.1 nM。
T28981	Tivirapine R-86183,R86183,8-Cl-TIBO,R 86183
	Tivirapine, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.
T61278	Aminopeptidase-IN-1	Aminopeptidase	Metabolism
	Aminopeptidase-IN-1 是一种有效的胰岛素调节氨肽酶 (IRAP) 抑制剂（Ki： 7.7 μM）。Aminopeptidase-IN-1 可用于认知和记忆障碍的研究。
T15479	HFI-142	Others	Others
	HFI-142 is an inhibitor of insulin-regulated aminopeptidase (IRAP) (Ki: 2.01 μM).
T32240	IVDE77 IVDE-77,IVDE 77
	IVDE77 is the first Ang IV-analogue with the ability to abolish IRAP-availability completely at the cell surface in vitro.
T61258	HFI-419
	HFI-419 is a potent inhibitor of insulin-regulated aminopeptidase (IRAP) with a K i value of 0.48 μM. It is utilized in research pertaining to cognitive and memory impairments, including Alzheimer's disease, brain trauma, and stroke [1].
T27160	DG026 DG 026,DG-026
	DG026 is a IRAP inhibitor. DG026 ables to selectively downregulate IRAP-dependent cross-presentation by dendritic cells but leave ERAP1-dependent cross-presentation unaffected.

化合物

Cat.No: T3231

Synonym: 尼拉帕尼,MK-4827

Target: Apoptosis, Others, PARP

Cat.No: T4434

Synonym: Tirazone,Win59075,SR4233,替拉扎明,SR259075

Target: Others

Niraparib hydrochloride

Cat.No: T3353

Synonym: 尼拉帕利盐酸盐,MK-4827 hydrochloride,MK-4827 (hydrochloride)

Target: Apoptosis, Others, PARP

Niraparib tosylate

Cat.No: T6892

Synonym: 尼拉帕利,MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate,尼拉帕尼对苯甲磺酸盐

Target: Apoptosis, PARP

Cat.No: T1595

Synonym: NSC 641530,奈韦拉平,BI-RG 587,奈伟拉平,NVP

Target: HIV Protease, Reverse Transcriptase

Ciraparantag acetate

Cat.No: T10820L1

Synonym: Ciraparantag acetate(1438492-26-2 Free base)

Target: Others

Niraparib (R-enantiomer)

Cat.No: T12064

Synonym: MK 4827 (R-enantiomer),Niraparib R-enantiomer

Target: PARP

Niraparib tosylate monohyrate

Cat.No: T9497

Target: PARP

Nevirapine quinone methide

Cat.No: T71517

Spirapril hydrochloride

Cat.No: T63425

Famiraprinium chloride

Cat.No: T68214

Nevirapine hemihydrate

Cat.No: T69796

Cat.No: T34696

Synonym: BRN4277924,BRN-4277924,BRN 4277924,Spiraprilum,Spirapril,Espirapril

Cat.No: T24820

Synonym: Spiraprilate,SCH-33861,SCH 33861,SCH33861

Nevirapine dimer

Cat.No: T70794

Cat.No: T10820

Synonym: PER977

Target: Others

Cat.No: T71524

Niraparib metabolite M1

Cat.No: T12229

Synonym: 尼拉帕尼代谢物,M1 metabolite of niraparib,Niraparib carboxylic acid metabolite M1

Target: Others

Ciraparantag TFA

Cat.No: T10820L

Synonym: PER977 TFA

Target: Others

12-Hydroxynevirapine

Cat.No: T74717

28-Epirapamycin

Cat.No: T74084

Cat.No: T28981

Synonym: R-86183,R86183,8-Cl-TIBO,R 86183

Aminopeptidase-IN-1

Cat.No: T61278

Target: Aminopeptidase

Cat.No: T15479

Target: Others

Cat.No: T32240

Synonym: IVDE-77,IVDE 77

Cat.No: T61258

Cat.No: T27160

Synonym: DG 026,DG-026

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00853	IL-1RA Protein, Human, Recombinant DIRA,IL1RA,interleukin 1 receptor antagonist,ICIL-1RA,MVCD4,...	Human	E. coli
	IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPJ-00909	IL-1RA Protein, Mouse, Recombinant IL-1RN,IRAP,Interleukin-1 Receptor Antagonist Prote...	Mouse	E. coli
	Interleukin-1 receptor antagonist protein (Il1rn), also known as IL-1ra, IRAP or IL1 inhibitor, is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1 alpha (IL1A) and interleukin 1 beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. The mouse Il1rn gene encodes a 178 amino acids (aa) protein with a 26 aa signal peptide. Mouse Il1rn protein shares 26% and 19% identity with its homologues IL-1 beta and I...
TMPY-00852	IL-1RA Protein, Human, Recombinant (hFc) interleukin 1 receptor antagonist,MVCD4,IRAP,IL1RA,...	Human	HEK293 Cells
	IL-1RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.8 kDa and the accession number is P18510-1.

重组蛋白

IL-1RA Protein, Human, Recombinant

Cat.No: TMPY-00853

Species: Human

Expression System: E. coli

IL-1RA Protein, Mouse, Recombinant

Cat.No: TMPJ-00909

Species: Mouse

Expression System: E. coli

IL-1RA Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00852

Species: Human

Expression System: HEK293 Cells

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼