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Cat. No.	Product Name	Target	Signaling Pathways
TP1122L	IGF-I 30-41 acetate(82177-09-1 free base) Insulin-like Growth Factor I (30-41) acetate	Others	Others
	IGF-I 30-41 acetate(82177-09-1 free base) (Insulin-like Growth Factor I (30-41) acetate) 是胰岛素样生长因子 I (IGF-I) 的氨基酸 30 至 41 片段。
TP1122	IGF-I (30-41) Insulin-like Growth Factor I (30-41),IGF-I 30-41
	IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I).
TP1124	IGF-I (24-41) Insulin-like Growth Factor I (24-41),IGF-I 24-41
	IGF-I (24-41) is a 24-41 amino acid fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective
TP1123	IGF-I (24-41) TFA (135861-49-3 free base) Insulin-like Growth Factor I (24-41) (TFA),IGF-I (24-41) TFA
	IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions).IGF-I (24-41) (TFA) is amino acids 24 to 41 fragment of Insulin-like Growth
TP1121	IGF-I (30-41) TFA(82177-09-1,FREE) Insulin-like Growth Factor I (30-41) (TFA)
	IGF-I (30-41) (TFA) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I).
T76012	IGF-I (30-41) (TFA)
	IGF-I (30-41) (TFA) 是类胰岛素生长因子I 30 至 41 的氨基酸片段。IGF-I 对生长激素的活性有着重要的作用，但是IGF-I 本身也具有一些自身的特性，如合成代谢、抗氧化、抗炎和细胞保护作用。
T76014	IGF-I (24-41) (TFA)
	IGF-I (24-41) TFA（Insulin-like Growth Factor I (24-41) TFA）是类胰岛素生长因子I的一个氨基酸片段，覆盖24至41位点。作为一种70个氨基酸组成的多肽激素，IGF-I TFA对神经元和神经胶质细胞具有营养作用，而且在调节全身生长激素（GH）活性中扮演关键角色。它还具备合成代谢、抗氧化、抗炎及细胞保护功能，对躯体生长及行为发育调节作用显著。
T11593	I-OMe-Tyrphostin AG 538 I-OMe-AG 538	IGF-1R; PI3K	PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	I-OMe-Tyrphostin AG 538是一种特异性 IGF-1R 抑制剂和 PI5P4Kα的 ATP 竞争性抑制剂（IC50：1 µM）。I-OMe-Tyrphostin AG 538可抑制 IGF-1R 介导的信号传导，并对营养缺乏的 PANC1细胞具有优先细胞毒性。
T2085	PQ401 IGF-1R Inhibitor II	Apoptosis; IGF-1R	Apoptosis; Tyrosine Kinase/Adaptors
	PQ401 (IGF-1R Inhibitor II) 是一种IGF-IR 抑制剂。在 MCF-7 细胞中，它抑制 IGF-I 刺激的 IGF-IR 自磷酸化，可有效抑制 IGF-I 刺激的 MCF-7 细胞生长。它诱导 caspase 介导的细胞凋亡，有用于乳腺癌和其他对 IGF-I 敏感的癌症的研究潜力。
T2160	Suramin Sodium Salt 苏拉明钠,BAY-205,Suramin hexasodium salt,苏拉明钠盐,NF-060	Apoptosis; Phosphatase; SARS-CoV; Sirtuin; Reverse Transcriptase; Topoisomerase; Parasite	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Suramin Sodium Salt (BAY-205) 是可逆的竞争性蛋白酪氨酸磷酸酶抑制剂。它抑制 IP5K，是抗寄生虫，抗肿瘤和抗血管生成剂。它是sirtuins 的有效抑制剂，也是 SARS-CoV-2 RNA 依赖性 RNA 聚合酶抑制剂。
TP2207	Pasireotide Acetate	Somatostatin	GPCR/G Protein
	Pasireotide acetate 是长效的环己肽生长激素抑制素类似物，具有抗分泌、抗增殖和促凋亡活性。它可抑制 GH、IGF-I 和 ACTH 的分泌，可用于研究肢端肥大症和库欣病。它还可以提高生长抑素受体的激动剂活性，对sst1、2、3、4、5的pKi 分别为 8.2、9.0、9.1、小于7.0 和 9.9。
T70568	H-1356
	H-1356 is an insulin-like growth factor 1(IGF-I) analog that inhibits autophosphorylation of IGF-I receptor.
T61506	NBI-31772 hydrate
	NBI-31772 hydrate is a powerful inhibitor of the interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs). It acts as a nonpeptide ligand, effectively releasing bioactive IGF-I from the IGF-I/IGFBP-3 complex (Ki values for all six human subtypes range from 1-24 nM). This compound demonstrates significant anxiolytic and antidepressant-like effects [1] [2] [3].
T20534	Lanreotide BIM 23014,Somatulin,Lanreotide Autogel,Somatuline,Ipstyl
	Lanreotide, a somatostatin analogue, suppresses GH/IGF-I hypersecretion in acromegaly patients. It also used to manage neuroendocrine tumours.
T73702	Mecasermin
	Mecasermin（Human IGF-I; FK 780），一种重组人胰岛素样生长因子I（IGF-I），主要用于研究因生长激素（GH）受体缺陷或GH抑制抗体导致的GH不敏感性而引起的生长障碍。
T69682	AEW541 HCl
	AEW541, also known as NVP-AEW541, is a novel, potent IGF-IR kinase inhibitor. NVP-AEW541 is capable of distinguishing between the IGF-IR (IC50 = 0.086 microM) and the closely related InsR (IC50 = 2.3 microM) in cells. NVP- AEW541 abrogates IGF-I-mediated survival and colony formation in soft agar at concentrations that are consistent with inhibition of IGF-IR autophosphorylation. Note: AEW541 has a Cis-configuration on the cyclobutane ring. Its CAS# is 475489-16-8. Many vendors and Sc-finder sc...
T69221	BMS-554417
	BMS-554417 is a novel inhibitor of IGF-IR, which inhibits IGF-IR and insulin receptor kinase activity and proliferation in vitro, and reduces tumor xenograft size in vivo. In a series of carcinoma cell lines, the IC50 for proliferation ranged from 120 nmol/L (Colo205) to >8.5 micromol/L (OV202). BMS-554417 treatment inhibited IGF-IR and insulin receptor signaling through extracellular signal-related kinase as well as the phosphoinositide 3-kinase/Akt pathway, as evidenced by decreased Akt phosph...

化合物

IGF-I 30-41 acetate(82177-09-1 free base)

Cat.No: TP1122L

Synonym: Insulin-like Growth Factor I (30-41) acetate

Target: Others

IGF-I (30-41)

Cat.No: TP1122

Synonym: Insulin-like Growth Factor I (30-41),IGF-I 30-41

IGF-I (24-41)

Cat.No: TP1124

Synonym: Insulin-like Growth Factor I (24-41),IGF-I 24-41

IGF-I (24-41) TFA (135861-49-3 free base)

Cat.No: TP1123

Synonym: Insulin-like Growth Factor I (24-41) (TFA),IGF-I (24-41) TFA

IGF-I (30-41) TFA(82177-09-1,FREE)

Cat.No: TP1121

Synonym: Insulin-like Growth Factor I (30-41) (TFA)

IGF-I (30-41) (TFA)

Cat.No: T76012

IGF-I (24-41) (TFA)

Cat.No: T76014

I-OMe-Tyrphostin AG 538

Cat.No: T11593

Synonym: I-OMe-AG 538

Target: IGF-1R, PI3K

Cat.No: T2085

Synonym: IGF-1R Inhibitor II

Target: Apoptosis, IGF-1R

Suramin Sodium Salt

Cat.No: T2160

Synonym: 苏拉明钠,BAY-205,Suramin hexasodium salt,苏拉明钠盐,NF-060

Target: Apoptosis, Phosphatase, SARS-CoV, Sirtuin, Reverse Transcriptase, Topoisomerase, Parasite

Pasireotide Acetate

Cat.No: TP2207

Target: Somatostatin

Cat.No: T70568

NBI-31772 hydrate

Cat.No: T61506

Cat.No: T20534

Synonym: BIM 23014,Somatulin,Lanreotide Autogel,Somatuline,Ipstyl

Cat.No: T73702

Cat.No: T69682

Cat.No: T69221

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