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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0863 |
Idoxuridine
IDU,碘苷,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid |
Antifection; HSV | Microbiology/Virology |
Idoxuridine (Dendrid) 是一种抑制病毒 DNA 合成的脱氧尿苷类似物,用作抗病毒剂。 | |||
T7886 |
Nidufexor
|
FXR; Autophagy | Autophagy; Metabolism |
Nidufexor 是一种可口服的法尼醇 X 受体激动剂,可研究非酒精性脂肪性肝炎。 | |||
T17232 |
Vidupiprant
AMG 853 |
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
Vidupiprant (AMG 853) 是一种有效的 CRTH2 和前列腺素 D 受体双重拮抗剂,在人源血浆中的 IC50 分别为 8 nM 和 35 nM。 Vidupiprant 可用于治疗哮喘的研究。 | |||
T11286 |
Fiduxosin
A 185980.1,ABT 980 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Fiduxosin 是一种具有选择性和有效性的 α1-adrenoceptor 拮抗剂,对 α1a-adrenoceptor,α1b-adrenoceptor 和 α1d-adrenoceptor 有抑制作用,Ki 值分别为 0.160 nM,24.9 nM 和 0.920 nM。Fiduxosin 可用于治疗良性前列腺增生。 | |||
T14298 |
Rimiducid
|
Apoptosis; Others; Fatty Acid Synthase | Apoptosis; Metabolism; Others |
Rimiducid 是一种可渗透脂质的他克莫司类似物,是一种二聚剂,通过交联 FKBP 结构域起作用。它将 Caspase 9 自杀开关二聚化并迅速诱导细胞凋亡。 | |||
T6088 |
Anidulafungin
LY303366,Eraxis,Ecalta,阿尼芬净 |
Others; Antibiotic; Antifungal | Microbiology/Virology; Others |
Anidulafungin (Ecalta) 是一种半合成的新棘球白素,具有抗真菌作用。 | |||
T69927 | Fiduxosin hydrochloride | ||
Fiduxosin hydrochloride is an alpha 1a-adrenoceptor antagonist that may be useful in the treatment of Benign Prostatic Hyperplasia. | |||
T36370 |
4-Methylumbelliferyl-α-L-Iduronide (free acid)
|
||
4-Methylumbelliferyl-α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans such as dermatan sulfate and heparin sulfate. 4-Methylumbelliferyl-α-L-iduronide is cleaved by α-L-iduronidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an... | |||
T74706 | Vidutolimod | ||
Vidutolimod 是一种CpG-A 类寡核苷酸,是TLR9的激动剂。Vidutolimod 激活浆细胞样树突状细胞(pDCs)并触发IFNα的释放,导致抗肿瘤免疫作用。 | |||
T74421 |
Pemvidutide
|
||
Pemvidutide 是一种GLP-1R/GCGR 双重激动剂,可导致体重、肝脏脂肪和血清脂质的显著降低。Pemvidutide 可用于非酒精性脂肪性肝炎 (NASH) 和肥胖症的研究。 | |||
T37560 |
Nidulin
|
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Nidulin is a depsidone originally isolated from A. nidulans. It is active against the bacteria M. tuberculosis and M. ranoe, as well as the fungi T. tonsurans and M. audouini. It also inhibits the growth of methicillin-resistant S. aureus (MRSA; MIC = 4 μg/ml) and has larvicidal activity toward Artemia (LC50 = 2.8 μg/ml). Nidulin is cytotoxic to MOLT-3 cells (IC50 = 21.2 μM) but not HuCCA-1, HepG2, or A549 cells (IC50s = >112.7 μM). It inhibits aromatase with an IC50 value of 11.2 μM. | |||
T125124 |
Nidurufin
|
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Nidurufin 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125124,CAS号为 28458-23-3。 | |||
T32138 | Iduronate 2-sulfate | ||
Iduronate 2-sulfate is a sulfatase enzyme related to Hunter syndrome. | |||
T76980 | Tidutamab | ||
Tidutamab (XmAb-18087) 是一种具有完整 Fc 结构域的人源化及亲和优化双特异性抗体(bsAb),旨在通过SSTR2和CD3两个靶点特异性结合来延长血清半衰期,通过激活T细胞介导的细胞毒性(RTcC)机制,有效消除SSTR+肿瘤细胞。 | |||
T78658 |
Pemvidutide TFA
|
||
Pemvidutide (TFA) 是一款针对GLP-1R/GCGR的双重激动剂,有助于显著降低体重、肝脏脂肪以及血清脂质水平。该化合物主要适用于非酒精性脂肪性肝炎(NASH)和肥胖症的研究领域。 | |||
T36541 |
Nornidulin
|
||
Nornidulin is a depsidone originally isolated from A. nidulans that has antibacterial activity against M. tuberculosis and M. ranoe as well as antifungal activity against T. tonsurans and M. audouini. It also inhibits the growth of methicillin-resistant S. aureus (MRSA; MIC = 2 μg/ml) and has larvicidal activity toward Artemia (LC50 = 1.7 μg/ml). Nornidulin has cytotoxic activity in MOLT-3 cells (IC50 = 35.7 μM) but not HuCCA-1, HepG2, or A549 cells (IC50s = >116.4 μM). | |||
T125076 |
Hispidulin 7-glucuronide
|
||
Hispidulin 7-glucuronide 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125076,CAS号为 31105-76-7。 | |||
T32925 | Luciduline | ||
Luciduline is a bioactive chemical. | |||
T125725 | Hispidulin 7-O-neohesperidoside | ||
Hispidulin 7-O-neohesperidoside 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125725。 | |||
T36111 |
L-Iduronic acid sodium salt
|
||
L-Iduronic acid sodium salt 是一种单糖,是肝素、硫酸乙酰肝素和硫酸皮肤素等糖胺聚糖 (GAG) 的重要成分。 | |||
T124577 |
Beta-D-glucopyranosiduronic acid
|
||
Beta-D-glucopyranosiduronic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124577。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TQ0201 |
Hispidulin
Dinatin |
Pim | Chromatin/Epigenetic; JAK/STAT signaling |
Hispidulin 是存在于豚草中的一种黄酮,是Pim-1抑制剂,IC50值为2.71 μM。 | |||
T3932 |
Viscidulin I
|
Others | Others |
Viscidulin I 存在于黄芩中,是一种天然产物。 | |||
TN2302 |
Viscidulin III
Ganhuangenin |
Glucosidase | Metabolism |
Viscidulin III (Ganhuangenin) 存在于黄芩中,可作为α-葡萄糖苷酶抑制剂。 | |||
TN4216 |
Hispidulin 4'-O-β-D-glucopyranoside
Hispidulin 4'-O-beta-D-glucopyranoside |
Others | Others |
Hispidulin 4'-O-β-D-glucopyranoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4216,CAS号为 244285-12-9。 | |||
T38928 |
Oleanolic acid-3-O-glucosyl(1-2)xylyl(1-3)glucosiduronic acid
|
||
Oleanolic acid-3-O-glucosyl(1-2)xylyl(1-3)glucosiduronic acid is a naturally occurring triterpene saponin. | |||
TN5239 |
Viscidulin III tetraacetate
|
Others | Others |
Viscidulin III tetraacetate 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5239,CAS号为 96684-81-0。 | |||
TN6645 | Lucidumol A | ||
Lucidumol A has relatively good effect against aldose reductase with IC50 of 19.1uM. Lucidumol A has cytotoxic activity, it reduced cell growth in three human carcinoma cells (Caco-2, HepG2, and HeLa cells) dose dependently with LC50s from 20.87 to 84.36 | |||
TN5238 |
Viscidulin II
|
IL Receptor; TNF | Apoptosis; Immunology/Inflammation |
Viscidulin II can be potential therapeutic agents against P. acnes-induced skin inflammation, it can significantly suppress P. acnes-induced IL-8 and IL-1β production in THP-1 cells, concomitant intradermal injection of viscidulin II with P. acnes can effectively attenuate P. acnes-induced ear swelling, and decrease the production of IL-6 and tumor necrosis factor-α in ear homogenates. | |||
TN6939 |
Lucidumoside C
|
||
Lucidumoside C is a natural product. |