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54

抑制剂 & 化合物

8

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T37081	HIOC
	Selective TrkB receptor agonist. Protects neurons from excitotoxicity. Protects retinas from light-induced retinal degeneration (LIRD) in vivo. Blood brain barrier and blood-retinal barrier penetrant.
T19758	D-alpha-Methylbenzyl isothiocyanate	Others	Others
	D-alpha-Methylbenzyl isothiocyanate 是一种抗氧化剂和手性试剂，可诱导 II 期酶活性。
T0823	Thioctamide Lipoamide,Thioctic acid amide,硫辛酰胺	Others	Others
	Thioctamide (Thioctic acid amide) 是 6, 8-dithiooctanoic amide 的俗称。它是 6, 8-dithiooctanoic amide 的功能形式，其中羧基通过酰胺键（包含 -NH2）与蛋白质（或任何其他胺）连接。
T40253	3-Phenylpropyl isothiocyanate	Others	Others
	3-Phenylpropyl isothiocyanate exhibits a potent inhibitory effect on N-nitrosomethyl-benzylamine (NMBA) tumorigenesis, thereby displaying strong chemopreventive properties [1] [2].
T3147	Pyrrolidinedithiocarbamate ammonium PDTC,Pyrrolidinedithiocarbamate,吡咯烷二硫代氨基甲酸铵,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate,吡咯烷二硫代甲酸铵	NF-κB	NF-κB
	Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt) 是一种选择性的、能透过血脑屏障的NF-κB 抑制剂。
T20058	Prothioconazole HSDB7893,HSDB-7893,Proline 480 SC Fungicide,JAU 6476,丙硫菌唑,HSDB 7893	Antifungal	Microbiology/Virology
	Prothioconazole (Proline 480 SC Fungicide) 是一种手性三唑类杀菌剂，用于植物病原控制。
TNU0436	2-Thiocytidine	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2-Thiocytidine 是一种靶向惰性淋巴系统恶性肿瘤的嘌呤核苷类似物，具有广泛的抗肿瘤活性。2-Thiocytidine 通过抑制 DNA 合成诱导细胞凋亡 (apoptosis) 。
T41248	Thiocolchicine	Microtubule Associated	Cytoskeletal Signaling
	Thiocolchicine 是一种有效的微管蛋白聚合抑制剂，IC50 为 2.5 µM，Ki 为 0.7 µM。 Thiocolchicine 诱导细胞凋亡。 Thiocolchicine 可用作 ADC 技术中的 ADC 细胞毒素。
T8422	DIETHYLDITHIOCARBAMIC ACID COPPER SALT Cupric diethyldithiocarbamate	Others	Others
	DIETHYLDITHIOCARBAMIC ACID COPPER SALT 是一种可用于各种金属、蛋白质和酶实验的螯合剂，也可作为络合剂合成包括杂环化合物在内的各种有机化合物，以及用作铜死亡的诱导剂。
T33811	Ophiocarpine l-Ophiocarpine
	Ophiocarpine is a protoberberine alkaloid.
T67227	Thiamine Thiocarbamate
	3-((((4-Amino-2-methylpyrimidin-5-yl)methyl)carbamothioyl)thio)-4-oxopentyl acetate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67227。
TP2416	Thioctoyl tripeptide-1 Lipoyl tripeptide-1,Lipovax
	Thioctoyl tripeptide-1 is a peptide.
T31387	Desferrithiocin DFT
	Desferrithiocin is a more active iron chelator than desferrioxamine.
T60559	S-(N-PhenethylthiocarbaMoyl)-L-cysteine
	S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys) 是一种抗癌剂。S-(N-PhenethylthiocarbaMoyl)-L-cysteine 具有抗白血病活性，可抑制 HL60 细胞中的 DNA 合成。S-(N-PhenethylthiocarbaMoyl)-L-cysteine 是P450的抑制剂。
T68770	Obidoxime thiocyanate
	Obidoxime thiocyanate is an AChE reactivator.
TNU0151	5-Methyl-4’-thiocytidine
	5-Methyl-4'-thiocytidine is a Nucleoside Derivative - Thio-nucleoside.
T25991	Promothiocin A Antibiotic SF2741A,Antibiotic SF 2741A,Antibiotic SF-2741A
	Promothiocin A is an antibiotic.
T66809	Guanidine thiocyanate
	Guanidine thiocyanate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66809，CAS号为 593-84-0。
T15695	L-Lysine thioctate	Others	Others
	L-Lysine thioctate is a lipoamidase substrate.
T35213	Xylyl isothiocyanate EINECS 275-839-0
	Xylyl isothiocyanate is a biochemical.
T83898	S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine SFN-Cys,D,L-Sulforaphane-L-cysteine
	S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine (SFN-Cys) 是一种异硫氰酸酯衍生物及第一类和第二类组蛋白去乙酰化酶（HDAC）抑制剂和抗癌剂硫代硫酸烯醇醚的活性代谢产物。它通过巯基乙酸途径酶从硫代硫酸烯醇醚经DL-硫代硫酸烯醇醚谷胱甘肽和硫代硫酸烯醇醚半胱氨酸甘肽中间体形成。SFN-Cys (20 µM) 通过创伤愈合和腔室分析实验，分别减少了U87MG和U373 MG胶质母细胞瘤细胞的侵袭和迁移。在45 µM的浓度下，它降低了对紫杉醇耐药的A549肺癌细胞（A549/T）中的α-微管蛋白、βIII-微管蛋白、司他敏1和X连锁抑制剂的凋亡（XIAP）的水平，并减少了细胞密度。使用30 µM浓度的SFN-Cys诱导U87MG和U373 MG细胞凋亡和G2/M期细胞周期停滞。
T13924	Thiochrome	Others	Others
	Thiochrome is a selective enhancer of M4 muscarinic receptor of acetylcholine (ACh) affinity.
TD0100	5(6)-TRITC [Tetramethylrhodamine-5-(and-6)-isothiocyanate] Mixed isomers
	5(6)-TRITC [Tetramethylrhodamine-5-(and-6) -Isothiocyanate] Mixed isomers is used to label antibodies with strong fluorescent dyes
T36096	Thiocoraline
	Thiocoraline is a depsipeptide and DNAbis-intercalator originally isolated fromMicromonosporawith antibacterial and anticancer activities.1,2It is active against the Gram-positive bacteriaS. aureus,B. subtilis, andM. luteus(MICs = 0.05, 0.05, and 0.03 μg/ml, respectively) but not Gram-negativeE. coli,K. pneumoniae, orP. aeruginosa(MICs = >100 μg/ml for all).1Thiocoraline inhibits RNA and DNA polymerase and thymidylate synthase (IC50s = 6, 6, and 15 μg/ml, respectively), as well as RNA and DNA sy...
T30143	Arsanil isothiocyanate
	Arsanil isothiocyanates, as arsanic acid conjugates, produce hapten-specific responses that can induce cell-mediated cytotoxicity based on hapten-binding patterns.
T26269	Thiocysteine
	Thiocysteine 是一种半胱氨酸衍生物，氨基酮戊酸盐合成酶的激活剂，可用于半胱氨酸代谢的研究。它也是一种抗肿瘤化合物。
T34849	Thiocystine
	Thiocystine can be produced in the hydrolysis of proteins.
T31356	Decyl thiocyanate Decylthiocyanate,Decylthiokyanat
	Decyl thiocyanate is a biochemical.
T32532	Lactosyl isothiocyanate LITC
	Lactosyl isothiocyanate is used as an affinity label for hexose transporter.
TNU0149	4’-Thiocytidine
	4'-Thiocytidine is a Thio-nucleoside.
T77264	Thiocholesterol
	Thiocholesterol 是一种胆固醇衍生物，常用于合成阳离子脂质液态晶体 (CLCs)。它也作为纳米银 (SNP) 的有效稳定剂。此外，Thiocholesterol 在质膜研究和药物递送领域有重要应用。
T83326	4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium
	4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium 是荧光染料，用于逆行轴突运输二抗标记显示和全细胞荧光染色。
TD0059	RBITC [Rhodamine B 5-isothiocyanate]
	Rhodamine B isothiocyanate is a mixture of isomers for fluorescence applications including fluorescent marking of proteins. It is derivatite of phenolphtalein.
T21464	Methiocarb Mercaptodimethur,Mesurol
	Methiocarb, a carbamate pesticide, is used as an insecticide, acaricide, bird repellent, and molluscicide. Methiocarb stimulates cholinergic by inhibiting reversibly acetylcholinesterase activity, making methiocarb a potent neurotoxin.
T27188	DL-alpha-Methylbenzyl isothiocyanate
	DL-alpha-Methylbenzyl isothiocyanate is an antioxidant used to induce phase II enzyme activity.
T21210	3-Iodophenylisothiocyanate
	3-Iodophenylisothiocyanate is a bioactive chemical.
T33229	m-Cresol thiocyanate
	m-Cresol thiocyanate is a bioactive chemical.
T64942	Fluorescein-6-isothiocyanate
	Fluorescein-6-isothiocyanate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64942，CAS号为 18861-78-4。
T21135	Decane, 1-isothiocyanato-
	Decane, 1-isothiocyanato- is a biochemical.
T20249	Fenothiocarb Phenothiocarb,KCO-3001,Panocon
	Fenothiocarb is an agent of pesticide.
T27793	L-alpha-Methylbenzyl isothiocyanate
	L-alpha-Methylbenzyl isothiocyanate is an antioxidant. It induces phase II enzyme activity and is also used as a chiral agent.
T13149	Thiocillin I	Antibacterial	Microbiology/Virology
	Thiocillin I is a thiopeptide antibiotic and has in vitro antibacterial activity against Gram-positive bacterial strains(MIC of Thiocillin I against S. aureus 1974149, E. faecalis 1674621, B. subtilis ATCC 6633 and S. pyogenes 1744264 are 2 μg/mL, 0.5 μg/mL, 4 μg/mL and 0.5 μg/mL, respectively).
T38150	Geninthiocin A
	Geninthiocin A is a cyclic thiopeptide bacterial metabolite originally isolated from Streptomyces sp. DD84. It is active against a variety of Gram-positive bacteria (MICs = 0.2-4 μg/ml), the Gram-negative bacterium C. violaceum (MIC = 19 μg/ml), and the fungus M. hiemalis (MIC = 38 μg/ml). Geninthiocin A also induces tipA promoter transcription with a minimum induction concentration of 1.2 ng/ml.
T81353	Pterostilbene-isothiocyanate PTER-ITC
	Pterostilbene-isothiocyanate (PTER-ITC) 在体外展现出显著的抗癌活性。它通过干扰β-catenin/TCF-4的相互作用，从而针对人骨肉瘤细胞发挥作用。
T21177	Benzene, 1-fluoro-3-isothiocyanato-
	Benzene, 1-fluoro-3-isothiocyanato- is a bioactive chemical.
T29479	6-Thiocaffeine
	6-Thiocaffeine is a bioactive chemical.
T32101	Homothiocystine
	Homothiocystine has appreciable activity as a substrate.
T13994	1-Isothiocyanato-PEG4-alcohol	Others	Others
	1-Isothiocyanato-PEG4-alcohol is a polyethylene glycol (PEG)-derived linker compound suitable for the incorporation into Proteolysis Targeting Chimeras (PROTACs)[1].
T38073	Thiocarlide Isoxyl
	Thiocarlide (isoxyl) is a thiourea derivative that was used in the 1960s to successfully treat tuberculosis (TB). It has considerable antimycobacterial activity in vitro and is effective against multi-drug resistant strains of Mycobacterium tuberculosis in the range of 1-10 &#181g/ml. [1] [2] At concentrations of 10 &#181M, isoxyl inhibits the synthesis of M. bovis during six hours of exposure which is similar to isoniazid (INH) and ethionamide (ETH), two other predominant anti-tuberculosis drug...
T37607	Rhodamine B isothiocyanate (mixed isomers)
	Rhodamine B isothiocyanate (RITC) is a cell-permeant fluorogenic dye most often used as a conjugate to antibodies and proteins for fluorescence detection in microscopy. It displays excitation/emission maxima of 570/595 nm, respectively, and can be used in conjunction with immunohistochemistry for multi-labeling studies. It has also been used as an anterograde and retrograde tracer in neurons and in nanoparticles to detect apoptosis.

化合物

Cat.No: T37081

D-alpha-Methylbenzyl isothiocyanate

Cat.No: T19758

Target: Others

Cat.No: T0823

Synonym: Lipoamide,Thioctic acid amide,硫辛酰胺

Target: Others

3-Phenylpropyl isothiocyanate

Cat.No: T40253

Target: Others

Pyrrolidinedithiocarbamate ammonium

Cat.No: T3147

Synonym: PDTC,Pyrrolidinedithiocarbamate,吡咯烷二硫代氨基甲酸铵,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate,吡咯烷二硫代甲酸铵

Target: NF-κB

Prothioconazole

Cat.No: T20058

Synonym: HSDB7893,HSDB-7893,Proline 480 SC Fungicide,JAU 6476,丙硫菌唑,HSDB 7893

Target: Antifungal

Cat.No: TNU0436

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cat.No: T41248

Target: Microtubule Associated

DIETHYLDITHIOCARBAMIC ACID COPPER SALT

Cat.No: T8422

Synonym: Cupric diethyldithiocarbamate

Target: Others

Cat.No: T33811

Synonym: l-Ophiocarpine

Thiamine Thiocarbamate

Cat.No: T67227

Thioctoyl tripeptide-1

Cat.No: TP2416

Synonym: Lipoyl tripeptide-1,Lipovax

Desferrithiocin

Cat.No: T31387

Synonym: DFT

S-(N-PhenethylthiocarbaMoyl)-L-cysteine

Cat.No: T60559

Obidoxime thiocyanate

Cat.No: T68770

5-Methyl-4’-thiocytidine

Cat.No: TNU0151

Cat.No: T25991

Synonym: Antibiotic SF2741A,Antibiotic SF 2741A,Antibiotic SF-2741A

Guanidine thiocyanate

Cat.No: T66809

L-Lysine thioctate

Cat.No: T15695

Target: Others

Xylyl isothiocyanate

Cat.No: T35213

Synonym: EINECS 275-839-0

S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine

Cat.No: T83898

Synonym: SFN-Cys,D,L-Sulforaphane-L-cysteine

Cat.No: T13924

Target: Others

5(6)-TRITC [Tetramethylrhodamine-5-(and-6)-isothiocyanate] *Mixed isomers*

Cat.No: TD0100

Cat.No: T36096

Arsanil isothiocyanate

Cat.No: T30143

Cat.No: T26269

Cat.No: T34849

Decyl thiocyanate

Cat.No: T31356

Synonym: Decylthiocyanate,Decylthiokyanat

Lactosyl isothiocyanate

Cat.No: T32532

Synonym: LITC

4’-Thiocytidine

Cat.No: TNU0149

Thiocholesterol

Cat.No: T77264

4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium

Cat.No: T83326

RBITC [Rhodamine B 5-isothiocyanate]

Cat.No: TD0059

Cat.No: T21464

Synonym: Mercaptodimethur,Mesurol

DL-alpha-Methylbenzyl isothiocyanate

Cat.No: T27188

3-Iodophenylisothiocyanate

Cat.No: T21210

m-Cresol thiocyanate

Cat.No: T33229

Fluorescein-6-isothiocyanate

Cat.No: T64942

Decane, 1-isothiocyanato-

Cat.No: T21135

Cat.No: T20249

Synonym: Phenothiocarb,KCO-3001,Panocon

L-alpha-Methylbenzyl isothiocyanate

Cat.No: T27793

Cat.No: T13149

Target: Antibacterial

Cat.No: T38150

Pterostilbene-isothiocyanate

Cat.No: T81353

Synonym: PTER-ITC

Benzene, 1-fluoro-3-isothiocyanato-

Cat.No: T21177

Cat.No: T29479

Homothiocystine

Cat.No: T32101

1-Isothiocyanato-PEG4-alcohol

Cat.No: T13994

Target: Others

Cat.No: T38073

Synonym: Isoxyl

Rhodamine B isothiocyanate (mixed isomers)

Cat.No: T37607

Cat. No.	Product Name	Target	Signaling Pathways
T2S1464	Thiocolchicoside 硫秋水仙苷;噻可撒可,Thiocolchicine 2-glucoside analog,硫秋水仙苷,Coltramyl	Others; GABA Receptor	Membrane transporter/Ion channel; Neuroscience; Others
	Thiocolchicoside (Thiocolchicine 2-glucoside analog) 是秋水仙碱的半合成硫衍生物，是竞争性 GABAA 受体拮抗剂和甘氨酸受体拮抗剂。它是肌肉松弛剂，具有抗炎作用，可用于缓解疼痛的研究。
T19687	Phenylethyl isothiocyanate JC 5411,2-苯基乙基异硫代氰酸酯,JC5411,JC-5411	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Phenylethyl isothiocyanate (JC5411) 是一种 HDAC 抑制剂。它有可能用于治疗良性前列腺肥大。
T1082	Benzyl isothiocyanate Benzoylthiocarbimide,苄基异硫氰酸酯,异硫氰酸苯甲酯,Isothiocyanic Acid Benzoyl Ester	Apoptosis; Antibacterial; Antibiotic	Apoptosis; Microbiology/Virology
	Benzyl isothiocyanate (Benzoylthiocarbimide) 是一种具有杀菌活性的天然异硫氰酸酯，最初存在于十字花科蔬菜中。它显示出免疫调节、抗寄生虫、抗生素、抗氧化、抗动脉粥样硬化、抗血管生成、抗转移、抗癌化疗和化学预防活性。
T3392	Sinapine thiocyanate	P-gp; AChE	Membrane transporter/Ion channel; Neuroscience
	Sinapine thiocyanate 是萝卜中分离出来的一种生物碱，具有抗炎、抗氧化、抗肿瘤、抗血管生成和放射防护作用。它还是乙酰胆碱酯酶抑制剂，可用于研究阿尔茨海默症，共济失调，重症肌无力和帕金森氏病。
TN6757	Butyl isothiocyanate	Others	Others
	Butyl isothiocyanate 是具有连接到氮的丁基的异硫氰酸酯。它具有作为半抗原的作用。
T8033	Sodium Thiocyanate	Others; Reactive Oxygen Species; Interleukin	Immunology/Inflammation; Metabolism; NF-κB; Others
	Sodium thiocyanate 能够减少促炎细胞因子 IL-6水平，并增强抗炎细胞因子 IL-10水平，并显著减少 ROS 形成。
T40866	8-Methylsulfinyloctyl isothiocyanate
	8-Methylsulfinyloctyl isothiocyanate is a compound with antimicrobial activity and notable inhibitory effects on plant growth. It also exhibits COX-2-mediated inflammatory response impairment in LPS-stimulated raw macrophages.
T11233	Erythromycin thiocyanate	Antibacterial	Microbiology/Virology
	Erythromycin thiocyanate acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid .Erythromycin thiocyanate

天然产物

Thiocolchicoside

Cat.No: T2S1464

Synonym: 硫秋水仙苷;噻可撒可,Thiocolchicine 2-glucoside analog,硫秋水仙苷,Coltramyl

Target: Others, GABA Receptor

Phenylethyl isothiocyanate

Cat.No: T19687

Synonym: JC 5411,2-苯基乙基异硫代氰酸酯,JC5411,JC-5411

Target: HDAC

Benzyl isothiocyanate

Cat.No: T1082

Synonym: Benzoylthiocarbimide,苄基异硫氰酸酯,异硫氰酸苯甲酯,Isothiocyanic Acid Benzoyl Ester

Target: Apoptosis, Antibacterial, Antibiotic

Sinapine thiocyanate

Cat.No: T3392

Target: P-gp, AChE

Butyl isothiocyanate

Cat.No: TN6757

Target: Others

Sodium Thiocyanate

Cat.No: T8033

Target: Others, Reactive Oxygen Species, Interleukin

8-Methylsulfinyloctyl isothiocyanate

Cat.No: T40866

Erythromycin thiocyanate

Cat.No: T11233

Target: Antibacterial

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