首页工具

登录

搜索结果

Search Results for " gnrh "

61

抑制剂 & 化合物

1

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
TP1342L	GnRH-I acetate GnRH-I acetate(33515-09-2 free base)	Others	Others
	GnRH-I acetate 在血液中释放具有生物活性的促卵泡激素 (FSH) 和促黄体激素 (LH)。
T21649L	GnRH Associated Peptide (GAP) (1-13), human Acetate GnRH Associated Peptide (GAP) (1-13), human Acetate (100111-07-7 Free base)	Others	Others
	GnRH Associated Peptide (GAP) (1-13), human Acetate 被发现是催乳素分泌的有效抑制剂并刺激促性腺激素的释放。用对应于 GAP 序列的肽进行主动免疫导致催乳素分泌大大增加。
T37003	GnRH antagonist 2
	GnRH antagonist 2 (formula I) is a potent GnRH receptor antagonist with valuable applications in endometriosis research[1].
TP1342	GnRH-I
	GnRH-I is a small 10 amino acid long peptide (decapeptide) from the hypothalamus,It is also known as luteinizing hormone releasing hormone (LHRH), is a key molecule in the regulation of reproduction in vertebrates. GnRH, a decapeptide, is produced by neur
T72492	GnRH-R antagonist 1	GNRH Receptor	GPCR/G Protein
	GnRH-R antagonist 1 (化合物 21a) 是GnRH-R拮抗剂，具有优良口服安全性及膜透性，高亲和力结合GnRH-R（IC50=0.57 nM），并展现出有效体外拮抗活性（IC50=2.18 nM）。该化合物适用于晚期前列腺癌治疗和预防过早LH峰出现的研究。
TP1288	Fertirelin	Others	Others
	Fertirelin 是 GnRH 和 LH-RH 的类似物，可用于研究牛滤泡囊肿。它是促性腺激素释放激素激动剂。
T76324	GnRH Associated Peptide (1-24), human
	GnRH Associated Peptide (GAP) (1-24), human 是人类的一个化合物，具体为促性腺激素释放激素相关肽(GAP)的第1至24个氨基酸片段(hGAP-1-24)。该化合物通过3个氨基酸加工位点与黄体生成素释放激素(LH-RH)序列连接。
T1494	Alarelin Acetate 阿拉瑞林,Alarelin	GNRH Receptor	GPCR/G Protein
	Alarelin Acetate 是一种合成的GnRH 激动剂。
T76323	GnRH Associated Peptide (25-53), human
	GnRH Associated Peptide (GAP) (25-53), human 是来源于人的促性腺激素释放激素相关肽（GAP）的一个特定片段，具体为第25至第53位氨基酸（hGAP-25-53）。本片段可用作免疫原，用以产生含有MC-1、MC-2和MC-3等抗体的抗血清。GAP通过其内含的三个氨基酸加工位点，能与黄体生成素释放激素（LH-RH）序列进行有效连接。
T3630	Relugolix RVT-601,瑞卢戈利,TAK-385	GNRH Receptor	GPCR/G Protein
	Relugolix (RVT-601) 是口服有活性的非肽性促性腺激素释放激素的拮抗剂。同 TAK-013 相比，它对人和猴子的受体具有高亲和力和强拮抗活性，它们的 IC50值分别为0.33 nM 和0.32 nM。它可用于研究性激素依赖性疾病，如子宫肌瘤、子宫内膜异位症、前列腺癌等。
T4102	Goserelin acetate 醋酸戈舍瑞林,Fertilan,ICI-118630 acetate,Zoladex	Apoptosis; GNRH Receptor	Apoptosis; GPCR/G Protein
	Goserelin acetate (Fertilan) 是一种促性腺激素释放激素 (GnRH/LHRH) 十肽类似物，能作为GnRH 激动剂。它可研究乳腺癌、上皮性卵巢癌和前列腺癌。
T27837	Linzagolix	GNRH Receptor	GPCR/G Protein
	Linzagolix 是一种口服有活性的非多肽GnRH 拮抗剂。可用于研究子宫肌瘤、子宫腺肌症、子宫内膜异位症。
T11174	(R)-Elagolix 恶拉戈利,NBI-56418	GNRH Receptor	GPCR/G Protein
	(R)-Elagolix (NBI-56418) 是口服具有活性的、选择性高的非肽类促性腺激素释放激素受体短期有效拮抗剂 (KD = 54 pM)。
T5520	Cetrorelix Acetate 醋酸西曲瑞克,Cetrorelix	GNRH Receptor	GPCR/G Protein
	Cetrorelix Acetate 是一种GnRH 受体的强效拮抗剂(IC50:1.21 nM)。
T5031	Elagolix sodium NBI-56418 sodium,恶拉戈利钠	GNRH Receptor	GPCR/G Protein
	Elagolix sodium (NBI-56418 sodium) 是人GnRH 受体拮抗剂，其IC50=0.25 nM，Ki=3.7 nM。
T10217L	Abarelix R3827,阿巴瑞克,PPI 149	GNRH Receptor	GPCR/G Protein
	Abarelix (PPI 149) 是一种促性腺激素释放激素 (GnRH) 拮抗剂，用于前列腺癌研究。
T5520L	Cetrorelix diacetate NS-75A,醋酸西曲瑞克,SB-075 acetate,SB-075 diacetate,Cetrorelix acetate,NS-75A diacetate	GNRH Receptor	GPCR/G Protein
	Cetrorelix diacetate (NS-75A) 是GnRH 受体的强效拮抗剂(IC50:1.21 nM)。
T21308	Histrelin Supprelin LA,组氨瑞林,Histrelin Acetate	Others	Others
	Histrelin (Supprelin LA) 是促性腺激素释放激素 (GnRH) 的九肽类似物，具有增加的效力。它被认为是 GnRH 激动剂。 Histrelin 用于治疗对激素敏感的男性前列腺癌和女性子宫肌瘤。
TP1700L	LGnRH-III, lamprey acetate(147859-97-0 free base)	GNRH Receptor	GPCR/G Protein
	LGnRH-III, lamprey acetate(147859-97-0 free base) 是 GnRH 家族进化上保守的成员，可刺激促性腺激素的分泌，同时刺激促黄体激素和促卵泡激素的分泌。
TP1700	LGnRH-III, lamprey
	GnRH III, an evolutionarily conserved member of the GnRH family, can stimulate the secretion of gonadotropins, it stimulates the secretion of both luteinizing and follicle-stimulating hormones.
T76312L	sGnRH-A acetate
	sGnRH-A醋酸盐是一种鲑鱼促性腺激素释放激素(GnRH)类似物。它能促进生长激素的分泌，并用作人工授精时的排卵诱导剂。
T76312	sGnRH-A
	sGnRH-A，一种鲑鱼促性腺激素释放激素(GnRH)类似物，能够促进生长激素的分泌，并作为人工授精中的排卵诱导剂使用。
T22025	AG 045572	P450; GNRH Receptor	GPCR/G Protein; Metabolism
	AG 045572 是一种有效的 GnRH 受体拮抗剂，对人类和大鼠的 GnRH receptor 具有抑制作用， Ki 值分别为 6.0 nM 和 3.8 nM。AG 045572 通过 CYP3A 代谢并抑制睾酮。
TP2323L	Deslorelin acetate(57773-65-6 free base) Deslorelin acetate	GNRH Receptor	GPCR/G Protein
	Deslorelin acetate(57773-65-6 free base) 是一种促性腺激素释放激素超级激动剂(GnRH agonist)
T25742	Linzagolix choline	GNRH Receptor	GPCR/G Protein
	Linzagolix choline 是一种可口服的非肽类的促性腺激素释放激素（GnRH）拮抗剂。可用于研究子宫肌瘤和子宫内膜异位症相关疼痛。
TP2337	Ganirelix Acetate	GNRH Receptor	GPCR/G Protein
	Ganirelix Acetate 是一种促性腺激素释放激素 (GnRH) 受体拮抗剂。
TP2107L	Histrelin acetate Histrelin acetate(76712-82-8 free base),醋酸组氨瑞林	GNRH Receptor	GPCR/G Protein
	Histrelin acetate 是促性腺激素释放激素 (GnRH) 的九肽类似物，具有增加的效力。当存在于血流中时，它作用于称为促性腺激素的垂体特定细胞。 Histrelin 刺激这些细胞释放促黄体激素和促卵泡激素。因此，它被认为是促性腺激素释放激素激动剂或 GnRH 激动剂。
TP1434L	Lecirelin acetate(61012-19-9 free base)	GNRH Receptor	GPCR/G Protein
	Lecirelin acetate(61012-19-9 free base) 是一种合成的 GnRH（促性腺激素释放激素）类似物，在治疗牛卵巢滤泡囊肿方面显示出很好的疗效。
T21309	Nafarelin acetate(76932-56-4 free base) RS-94991-298,醋酸萘法瑞林,Nafarelin acetate,Nafarelin acetate hydrate,Synarel	GNRH Receptor	GPCR/G Protein
	Nafarelin acetate(76932-56-4 free base) (RS-94991-298) 是一种 GnRH 激动剂，可作为 GnRH 的类似物。 Nafarelin acetate(76932-56-4 free base) 导致促性腺激素促黄体激素 (LH) 和促卵泡激素 (FSH) 的垂体分泌减少。它可用于治疗雌激素依赖性病症。
TP1896L1	Kisspeptin 234 acetate(1145998-81-7 free base)	GPR; Kisspeptin	Endocrinology/Hormones; GPCR/G Protein
	Kisspeptin 234 acetate(1145998-81-7 free base) 是Kisspeptin 受体 (KISS1, GPR54) 拮抗剂；是Kisspeptin-10 类似物。它抑制 Kisspeptin-10 对磷酸肌醇 (IP) (IC50 = 7 nM) 的刺激和促性腺激素释放激素 (GnRH) 的释放。
T21410	Triptorelin acetate(57773-63-4 free base) 醋酸曲普瑞林,Wy 42422,Triptorelin Acetate,CL 118532,AY 25650,CL 118,532,Wy 42462,BIM 21003	GNRH Receptor	GPCR/G Protein
	Triptorelin acetate(57773-63-4 free base) (CL 118,532) 用作 GnRH 激动剂。它通过引起垂体的持续刺激来减少垂体促性腺激素促黄体激素 (LH) 和促卵泡激素 (FSH) 的分泌。曲普瑞林可用于治疗激素反应性癌症，如乳腺癌或前列腺癌、性早熟、雌激素依赖性疾病和辅助生殖。
T3489	Dasabuvir ABT-333,达塞布韦	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Dasabuvir (ABT-333) 是丙型肝炎病毒非结构蛋白 5B 的非核苷抑制剂，是一种 RNA 依赖性 RNA 聚合酶，具有抗 HCV 的潜在活性。
T23412	T 98475	Others	Others
	gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist,orally active
T10475	BAY-784	Others	Others
	BAY-784 is a gonadotropin-releasing hormone receptor (GnRH-R) antagonist (IC50s: 21 and 24 nM for human and rat GnRH-R).
T75244	Acyline TFA
	Acyline TFA，GnRH 多肽类似物，是一种GnRH 拮抗剂，可以抑制促性腺激素和睾酮 (T) 水平。
T68915	Fertirelin acetate
	Fertirelin acetate is a gonadotropin-releasing hormone (GnRH) agonist.
T80422	Phoenixin-14 PNX-14	GNRH Receptor	GPCR/G Protein
	Phoenixin-14 (PNX-14) 是一种具有内源性活性的异构体，能通过激活AHA GnRH系统发挥抗焦虑效果，并抑制缺血/再灌注所诱导的小胶质细胞毒性。
T75991	Ganirelix
	Ganirelix为一种竞争性且选择性的促性腺激素释放激素(GnRH)拮抗剂，其主要作用机制为抑制内源性GnRH，从而抑制黄体生成素(LH)及促卵泡激素的释放。
T71149	Triptorelin pamoate
	Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, es...
T76351	[D-Ala6]-LH-RH
	[D-Ala6]-LH-RH，一种黄体激素释放激素(LHRH)模拟物，充当GnRH受体的激动剂。
T70309	Dicetrorelix pamoate
	Dicetrorelix pamoate is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Due to a positive estradiol (E2) feedback at midcycle, GnRH liberation is enhanced resulting in an LH-surge. This LH-surge induces the ovulation of the dominant follicle, resumption of oocyte meiosis and subsequently lutein...
T10217	Abarelix Acetate (183552-38-7 free base) PPI 149 Acetate,Abarelix Acetate	Others	Others
	Abarelix (PPI 149; R 3827) Acetate is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer research.
T73327	Merigolix
	Merigolix 是一种有效的促性腺激素释放激素GnRH 拮抗剂。
T76350	[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH
	[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH 是一种黄体激素释放激素 (LHRH) 类似物，可作为 GnRH 受体拮抗剂。
T69383	NBI-42902
	NBI-42902 is a potent inhibitor of peptide radioligand binding to the human GnRH receptor (K(i) = 0.56 nm). Tritiated NBI-42902 binds with high affinity (K(d) = 0.19 nm) to a single class of binding sites and can be displaced by a range of peptide and nonpeptide GnRH receptor ligands. In vitro experiments demonstrate that NBI-42902 is a potent functional, competitive antagonist of GnRH stimulated IP accumulation, Ca(2+) flux, and ERK1/2 activation. It did not stimulate histamine release from rat...
T70266	Acyline
	Acyline is a novel GnRH antagonist found in animal studies to be a potent suppressor of circulating gonadotropin and testosterone (T) levels. Acyline inhibits basal and GnRH-stimulated serum testosterone concentrations in male dogs. Acyline prevented ovulation, but did not affect ovarian follicular development or gestational corpora lutea in the domestic cat. A single dose of the potent gonadotropin-releasing hormone antagonist acyline suppresses gonadotropins and testosterone for 2 weeks in hea...
T76348	[D-Lys6]-LH-RH
	[D-Lys6]-LH-RH 是一种黄体激素释放激素 (LHRH) 类似物，可作为GnRH 受体激动剂。
T68525	Nafarelin acetate hydrate
	Nafarelin is a gonadotropin-releasing hormone agonist (GnRH agonist) which acts as an analog of GnRH. Nafarelin increases the release of FSH and LH by the anterior pituitary, which in turn leads to an increase of estrogen/progesterone. When administered, Nafarelin has the purpose of causing increase estrogen that will negatively feed back upon hypothalamus to decrease GnRH ( negative feedback loop ) Through negative feedback, Nafarelin causes a decrease in pituitary secretion of gonadotropins lu...
T28795	SKI2496 SKI 2496,SKI-2496
	SKI2496 is a potent and orally bioavailableantagonist of Gonadotropin-Releasing Hormone Receptor (hGnRHR IC50 = 0.46 nM; max. LH inh. inh. (%, h)= 84%, 12h; LH inh. (24h) = 76%.). SKI2496 exhibits more selective antagonistic activity toward the human GnRH
TP1896	Kisspeptin 234
	kisspeptin receptor (KISS1, GPR54) antagonist; kisspeptin-10 analog. Inhibits kisspeptin-10 stimulation of inositol phosphate (IP) (IC50 = 7 nM) and release of gonadotrophin-releasing hormone (GnRH).

化合物

GnRH-I acetate

Cat.No: TP1342L

Synonym: GnRH-I acetate(33515-09-2 free base)

Target: Others

GnRH Associated Peptide (GAP) (1-13), human Acetate

Cat.No: T21649L

Synonym: GnRH Associated Peptide (GAP) (1-13), human Acetate (100111-07-7 Free base)

Target: Others

GnRH antagonist 2

Cat.No: T37003

Cat.No: TP1342

GnRH-R antagonist 1

Cat.No: T72492

Target: GNRH Receptor

Cat.No: TP1288

Target: Others

GnRH Associated Peptide (1-24), human

Cat.No: T76324

Alarelin Acetate

Cat.No: T1494

Synonym: 阿拉瑞林,Alarelin

Target: GNRH Receptor

GnRH Associated Peptide (25-53), human

Cat.No: T76323

Cat.No: T3630

Synonym: RVT-601,瑞卢戈利,TAK-385

Target: GNRH Receptor

Goserelin acetate

Cat.No: T4102

Synonym: 醋酸戈舍瑞林,Fertilan,ICI-118630 acetate,Zoladex

Target: Apoptosis, GNRH Receptor

Cat.No: T27837

Target: GNRH Receptor

Cat.No: T11174

Synonym: 恶拉戈利,NBI-56418

Target: GNRH Receptor

Cetrorelix Acetate

Cat.No: T5520

Synonym: 醋酸西曲瑞克,Cetrorelix

Target: GNRH Receptor

Elagolix sodium

Cat.No: T5031

Synonym: NBI-56418 sodium,恶拉戈利钠

Target: GNRH Receptor

Cat.No: T10217L

Synonym: R3827,阿巴瑞克,PPI 149

Target: GNRH Receptor

Cetrorelix diacetate

Cat.No: T5520L

Synonym: NS-75A,醋酸西曲瑞克,SB-075 acetate,SB-075 diacetate,Cetrorelix acetate,NS-75A diacetate

Target: GNRH Receptor

Cat.No: T21308

Synonym: Supprelin LA,组氨瑞林,Histrelin Acetate

Target: Others

LGnRH-III, lamprey acetate(147859-97-0 free base)

Cat.No: TP1700L

Target: GNRH Receptor

LGnRH-III, lamprey

Cat.No: TP1700

sGnRH-A acetate

Cat.No: T76312L

Cat.No: T76312

Cat.No: T22025

Target: P450, GNRH Receptor

Deslorelin acetate(57773-65-6 free base)

Cat.No: TP2323L

Synonym: Deslorelin acetate

Target: GNRH Receptor

Linzagolix choline

Cat.No: T25742

Target: GNRH Receptor

Ganirelix Acetate

Cat.No: TP2337

Target: GNRH Receptor

Histrelin acetate

Cat.No: TP2107L

Synonym: Histrelin acetate(76712-82-8 free base),醋酸组氨瑞林

Target: GNRH Receptor

Lecirelin acetate(61012-19-9 free base)

Cat.No: TP1434L

Target: GNRH Receptor

Nafarelin acetate(76932-56-4 free base)

Cat.No: T21309

Synonym: RS-94991-298,醋酸萘法瑞林,Nafarelin acetate,Nafarelin acetate hydrate,Synarel

Target: GNRH Receptor

Kisspeptin 234 acetate(1145998-81-7 free base)

Cat.No: TP1896L1

Target: GPR, Kisspeptin

Triptorelin acetate(57773-63-4 free base)

Cat.No: T21410

Synonym: 醋酸曲普瑞林,Wy 42422,Triptorelin Acetate,CL 118532,AY 25650,CL 118,532,Wy 42462,BIM 21003

Target: GNRH Receptor

Cat.No: T3489

Synonym: ABT-333,达塞布韦

Target: HCV Protease

Cat.No: T23412

Target: Others

Cat.No: T10475

Target: Others

Cat.No: T75244

Fertirelin acetate

Cat.No: T68915

Cat.No: T80422

Synonym: PNX-14

Target: GNRH Receptor

Cat.No: T75991

Triptorelin pamoate

Cat.No: T71149

Cat.No: T76351

Dicetrorelix pamoate

Cat.No: T70309

Abarelix Acetate (183552-38-7 free base)

Cat.No: T10217

Synonym: PPI 149 Acetate,Abarelix Acetate

Target: Others

Cat.No: T73327

[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH

Cat.No: T76350

Cat.No: T69383

Cat.No: T70266

Cat.No: T76348

Nafarelin acetate hydrate

Cat.No: T68525

Cat.No: T28795

Synonym: SKI 2496,SKI-2496

Cat.No: TP1896

Cat. No.	Product Name	Target	Signaling Pathways
T40458	3-Keto petromyzonol
	3-Keto petromyzonol, a key constituent of Sea lamprey male sex pheromones, governs the synthesis and release of gonadotropin releasing hormone (GnRH). This in turn regulates the hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey.

天然产物

3-Keto petromyzonol

Cat.No: T40458

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼