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Cat. No.	Product Name	Target	Signaling Pathways
T8328	STING agonist-1 G10	Virus Protease; STING	Immunology/Inflammation; Microbiology/Virology
	STING agonist-1 (G10)是一种人类特异性 STING 激动剂，可引发针对新兴甲病毒的抗病毒活性。它抑制甲病毒属 VEEV 复制，IC90值为 24.57 μM。
T2038	RG108 N-Phthalyl-L-tryptophan	DNA Methyltransferase	Chromatin/Epigenetic
	RG108 (N-Phthalyl-L-tryptophan) 是一种非核苷的 DNA 甲基转移酶 (DNMTs) 抑制剂，IC50为115 nM。它阻断 DNA 甲基转移酶的活性位点，可引起抑癌基因的去甲基化和再激活。
T18031	Hydroxy-PEG10-acid HO-PEG10-CH2CH2COOH	Others; PROTAC Linker	Others; PROTAC
	Hydroxy-PEG10-acid (HO-PEG10-CH2CH2COOH) 是 PEG 类 PROTAC linker。可用于合成 PROTAC 分子。
T3065	TG101209	Apoptosis; FLT; c-RET; JAK; Autophagy	Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	TG101209 是一种选择性有效的 JAK2抑制剂，IC50值为 6 nM。它能抑制 Flt3和RET 的活性，IC50值分别为 25 nM 和 17 nM。
T17402	Amino-PEG10-acid	Others; PROTAC Linker	Others; PROTAC
	Amino-PEG10-acid 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T2672	TG100-115	PI3K	PI3K/Akt/mTOR signaling
	TG100-115 是 PI3Kγ/PI3Kδ 的选择性抑制剂，IC50分别为 83 和 235 nM。
T67839	HG106	Others	Others
	HG106具有抗炎作用，可用于治疗由 RAS 基因突变引起的各种恶性肿瘤等疾病的生长。
T14413	Azido-PEG10-alcohol 叠氮-十聚乙二醇	Others; PROTAC Linker	Others; PROTAC
	Azido-PEG10-alcohol 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T17964	Fmoc-NH-PEG10-acid FMOC酰胺-十聚乙二醇-丙酸	Others; PROTAC Linker	Others; PROTAC
	Fmoc-NH-PEG10-acid 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T2693	AG1024 Tyrphostin AG 1024,Tyrphostin,AGS 200	Apoptosis; IGF-1R	Apoptosis; Tyrosine Kinase/Adaptors
	AG1024 (Tyrphostin) 是一种可逆的，竞争性和选择性的胰岛素样生长因子-1 受体抑制剂，IC50为 7 μM。它抑制胰岛素受体的磷酸化，IC50值为 57 μM。它诱导细胞凋亡并具有抗癌活性。
T18253	Mal-NH-PEG10-CH2CH2COOPFP ester	Others	Others
	Mal-NH-PEG10-CH2CH2COOPFP ester is a polyethylene glycol (PEG)-based linker molecule employed in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
T19703	LG100268 LG 100268,LG-100268
	LG100268 is an effective and selective rexinoid and retinoid-X receptor agonist. LG100268 binds to the α, β, and γ RXR receptors (IC50 = 3-4 nM).
T15748	LG100754 UVI 2112	PPAR	DNA Damage/DNA Repair; Metabolism
	LG100754 (UVI 2112)是一种通过RXR 发挥作用的胰岛素增敏剂。LG100754是RXR 二聚体调节剂。LG100754是RXR:RXR 同二聚体拮抗剂，以及RXR:PPARα和RXR:PPPARγ异二聚体的激动剂。
T17479	Azido-PEG10-Boc	Others	Others
	Azido-PEG10-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18007	HO-PEG10-CH2COOH	Others	Others
	HO-PEG10-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17714	Cbz-N-PEG10-acid	Others	Others
	Cbz-N-PEG10-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18835	Thiol-PEG10-alcohol HS-PEG10-OH	Others	Others
	Thiol-PEG10-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T14629	Bis-PEG10-acid	Others	Others
	Bis-PEG10-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17167	Trityl-PEG10-azide	Others	Others
	Trityl-PEG10-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T15837	m-PEG10-Tos	Others	Others
	m-PEG10-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18547	(+)-Biotin-PEG10-OH (+)-Biotin-PEG10-alcohol	Others	Others
	(+)-Biotin-PEG10-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17661	Boc-NH-PEG10-CH2CH2COOH	Others	Others
	Boc-NH-PEG10-CH2CH2COOH is a polyethylene glycol (PEG)-based PROTAC linker utilized for PROTAC synthesis[1].
T15835	m-PEG10-amine	Others	Others
	m-PEG10-amine is a 10-unit polyethylene glycol (PEG) linker that is non-cleavable. It serves as an essential component in the synthesis of antibody-drug conjugates (ADCs)[1]. Additionally, m-PEG10-amine functions as a PEG-based linker in the synthesis of PROTACs[1], effectively facilitating their formation.
T39968	TLR7/8 agonist 4 hydroxy-PEG10-acid TLR7/8 agonist 4 hydroxy-PEG10-acid
	TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a drug-linker conjugate employed in antibody-drug conjugates (ADC). This compound exhibits remarkable antitumor activity by utilizing TLR7/8 agonist 4, which acts as a potent activator of TLR7/8. The TLR7/8 agonist 4 is linked to hydroxy-PEG10-acid, the ADC linker, via a cleavable bond. Overall, it demonstrates promising pharmaceutical potential in the context of ADC-based therapeutics.
T39970	TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride
	TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate used in antibody-drug conjugates (ADCs) with high efficacy against tumors. It consists of TLR7/8 agonist 4, a potent TLR7/8 agonist, linked to the ADC linker hydroxy-PEG10-acid which can be cleaved.
T73510	ZG1077
	ZG1077 是一种共价的KRAS G12C 抑制剂。ZG1077 可用于非小细胞肺癌 (NSCLC) 的研究。
T75848	PG106 TFA
	PG106 TFA 是一种有效的、选择性的 hMC3 receptor 拮抗剂 (IC50= 210 nM)，对 hMC4 受体(EC50=9900 nM) 和 hMC5 受体无活性。
TP1952	PG106 PG 106
	Selective hMC3 receptor antagonist (IC50 = 210 nM). Exhibits no activity at hMC4 receptors and hMC5 receptors.
T17718	Cbz-NH-PEG10-CH2COOH	Others	Others
	Cbz-NH-PEG10-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T40533	THP-PEG10-THP THP-PEG10-THP
	THP-PEG10-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T16593	Propargyl-PEG10-acid	Others	Others
	Propargyl-PEG10-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T40532	MS-PEG10-THP MS-PEG10-THP
	MS-PEG10-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T14224	Amino-PEG10-Boc	Others	Others
	Amino-PEG10-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18071	LG-PEG10-click-DBCO-Oleic	Others	Others
	LG-PEG10-click-DBCO-Oleic is a polyethylene glycol (PEG) derivative utilized as a linker in the creation of Proteolysis Targeting Chimeras (PROTACs)[1].
T15834	m-PEG10-alcohol Decaethylene glycol monomethyl ether	Others	Others
	m-PEG10-alcohol, also known as Decaethylene glycol monomethyl ether, is a non-cleavable 10 unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1]. Additionally, m-PEG10-alcohol serves as a PEG-based PROTAC linker, enabling its application in the synthesis of PROTACs[1].
T18118	m-PEG10-Boc	Others	Others
	m-PEG10-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T16594	Propargyl-PEG10-amine	Others	Others
	Propargyl-PEG10-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18122	m-PEG10-SH	Others	Others
	m-PEG10-SH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T41047	Benzyl-PEG10-alcohol Benzyl-PEG10-alcohol
	Benzyl-PEG10-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17403	Amino-PEG10-CH2-Boc	Others	Others
	Amino-PEG10-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17662	Boc-NH-PEG10-CH2CH2NH2	Others	Others
	Boc-NH-PEG10-CH2CH2NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T14412	Azido-PEG10-acid	Others	Others
	Azido-PEG10-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18120	m-PEG10-CH2COOH	Others	Others
	m-PEG10-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17781	DBCO-PEG10-DBCO	Others	Others
	DBCO-PEG10-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18119	m-PEG10-Br	Others	Others
	m-PEG10-Br is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T69903	SKOG102
	SKOG102 是一种有效的 OLIG2抑制剂，可直接与 OLIG2 结合并干扰 OLIG2 结合 DNA 的能力。SKOG102 可用于胶质母细胞瘤 (GBM) 的研究。
T14225	Amino-PEG10-OH	Others	Others
	Amino-PEG10-OH is non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
T18117	m-PEG10-acid	Others	Others
	m-PEG10-acid is a non-cleavable 10-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker [1]. Furthermore, m-PEG10-acid serves as a PEG-based linker for the synthesis of proteolysis-targeting chimeras (PROTACs) [2].
T14223	Amino-PEG10-amine	Others	Others
	Amino-PEG10-amine is a PEG-based PROTAC linker employed for the conjugation of two mono diethylstilbestrol (DES)-based ligands. This compound offers an alternative approach to the synthesis of highly selective and active ER antagonists, which are crucial for the advancement of endocrine therapy in breast cancer treatment[1].
T78034	ANG1005
	ANG1005是一种紫杉烷类衍生物，采用三个紫杉醇分子与Angiopep-2共价结合而成的脑穿透肽活性分子偶联物。此化合物设计用于利用低密度脂蛋白受体相关蛋白（LRP1）运输系统，穿透血脑和血脑脊髓屏障，进而作用于恶性细胞。

化合物

STING agonist-1

Cat.No: T8328

Synonym: G10

Target: Virus Protease, STING

Cat.No: T2038

Synonym: N-Phthalyl-L-tryptophan

Target: DNA Methyltransferase

Hydroxy-PEG10-acid

Cat.No: T18031

Synonym: HO-PEG10-CH2CH2COOH

Target: Others, PROTAC Linker

Cat.No: T3065

Target: Apoptosis, FLT, c-RET, JAK, Autophagy

Amino-PEG10-acid

Cat.No: T17402

Target: Others, PROTAC Linker

Cat.No: T2672

Target: PI3K

Cat.No: T67839

Target: Others

Azido-PEG10-alcohol

Cat.No: T14413

Synonym: 叠氮-十聚乙二醇

Target: Others, PROTAC Linker

Fmoc-NH-PEG10-acid

Cat.No: T17964

Synonym: FMOC酰胺-十聚乙二醇-丙酸

Target: Others, PROTAC Linker

Cat.No: T2693

Synonym: Tyrphostin AG 1024,Tyrphostin,AGS 200

Target: Apoptosis, IGF-1R

Mal-NH-PEG10-CH2CH2COOPFP ester

Cat.No: T18253

Target: Others

Cat.No: T19703

Synonym: LG 100268,LG-100268

Cat.No: T15748

Synonym: UVI 2112

Target: PPAR

Azido-PEG10-Boc

Cat.No: T17479

Target: Others

HO-PEG10-CH2COOH

Cat.No: T18007

Target: Others

Cbz-N-PEG10-acid

Cat.No: T17714

Target: Others

Thiol-PEG10-alcohol

Cat.No: T18835

Synonym: HS-PEG10-OH

Target: Others

Cat.No: T14629

Target: Others

Trityl-PEG10-azide

Cat.No: T17167

Target: Others

Cat.No: T15837

Target: Others

(+)-Biotin-PEG10-OH

Cat.No: T18547

Synonym: (+)-Biotin-PEG10-alcohol

Target: Others

Boc-NH-PEG10-CH2CH2COOH

Cat.No: T17661

Target: Others

Cat.No: T15835

Target: Others

TLR7/8 agonist 4 hydroxy-PEG10-acid

Cat.No: T39968

Synonym: TLR7/8 agonist 4 hydroxy-PEG10-acid

TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride

Cat.No: T39970

Synonym: TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride

Cat.No: T73510

Cat.No: T75848

Cat.No: TP1952

Synonym: PG 106

Cbz-NH-PEG10-CH2COOH

Cat.No: T17718

Target: Others

Cat.No: T40533

Synonym: THP-PEG10-THP

Propargyl-PEG10-acid

Cat.No: T16593

Target: Others

Cat.No: T40532

Synonym: MS-PEG10-THP

Amino-PEG10-Boc

Cat.No: T14224

Target: Others

LG-PEG10-click-DBCO-Oleic

Cat.No: T18071

Target: Others

m-PEG10-alcohol

Cat.No: T15834

Synonym: Decaethylene glycol monomethyl ether

Target: Others

Cat.No: T18118

Target: Others

Propargyl-PEG10-amine

Cat.No: T16594

Target: Others

Cat.No: T18122

Target: Others

Benzyl-PEG10-alcohol

Cat.No: T41047

Synonym: Benzyl-PEG10-alcohol

Amino-PEG10-CH2-Boc

Cat.No: T17403

Target: Others

Boc-NH-PEG10-CH2CH2NH2

Cat.No: T17662

Target: Others

Azido-PEG10-acid

Cat.No: T14412

Target: Others

m-PEG10-CH2COOH

Cat.No: T18120

Target: Others

DBCO-PEG10-DBCO

Cat.No: T17781

Target: Others

Cat.No: T18119

Target: Others

Cat.No: T69903

Cat.No: T14225

Target: Others

Cat.No: T18117

Target: Others

Amino-PEG10-amine

Cat.No: T14223

Target: Others

Cat.No: T78034

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