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Search Results for " chelating "

61

抑制剂 & 化合物

9

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T7887	8-Hydroxyquinoline hemisulfate 8-羟基喹啉硫酸盐,Oxyquinoline sulfate	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	8-Hydroxyquinoline hemisulfate (Oxyquinoline sulfate) 是一种单质子双齿螯合剂，具有温和的抑菌、驱虫和杀螨作用。
T19963	Alizarin Complexone Alizarin Fluorine Blue,Alizarin-3-methyliminodiacetic acid,茜素络合指示剂	Reverse Transcriptase	Microbiology/Virology
	Alizarin Complexone (Alizarin-3-methyliminodiacetic acid) 是 Rous 相关病毒 2 逆转录酶的抑制剂。 Alizarin Complexone 可用作生物研究的钙示踪剂和螯合剂。
T1457	Deferasirox ICL 670,CGP-72670,地拉罗司	Others; Ferroptosis; Antibacterial	Apoptosis; Microbiology/Virology; Others
	Deferasirox (CGP-72670) 是一种口服铁螯合剂，用于治疗慢性铁过载。
T22321	edetate calcium disodium EDTA calcium disodium,乙二胺四乙酸二钠钙	Others	Others
	Edetate calcium disodium(EDTA calcium disodium) 是一种螯合剂，主要用于治疗严重的铅中毒。
T15055	DB04760 MMP-13 Inhibitor	MMP	Proteases/Proteasome
	DB04760 是一种高选择性和有效的 MMP-13 非锌螯合抑制剂（IC50：8 nM）。DB04760 能明显降低紫杉醇的神经毒性，并具有抗癌活性。
T8500	VLX600	OXPHOS; Mitochondrial Metabolism; Autophagy	Apoptosis; Autophagy; Metabolism
	VLX600 是一种铁螯合氧化磷酸化抑制剂，是一种细胞渗透性抗癌剂。它通过减少肿瘤细胞中的线粒体氧化磷酸化起作用。
T19936	Xantphos
	Xantphos 是 Buchwald, Suzuki 等偶联反应中的配体，是可用于催化反应的金属螯合配体。
T2552	Succimer DMSA,Dimercaptosuccinic acid,二巯基丁二酸,meso-2,3-dimercaptosuccinic acid,内消旋-2,3-二巯基丁二酸	Others	Others
	Succimer (Dimercaptosuccinic acid) 是一种螯合剂，广泛用于铅中毒的研究。
T65232	HEDTA N-(2-Hydroxyethyl)ethylenediaminetriacetic acid	Others	Others
	HEDTA 是一种螯合剂，常与柠檬酸联合用药来研究血液疾病和脑部血液应激。
T21300	Trientine-2HCl Triethylenetetramine,Trientine HCl,Trientine,盐酸三乙烯四胺,Triethylene tetramine,TETA,Trien	Others	Others
	Trientine-2HCl (Trien) 是一种螯合剂，通过结合和去除体内的铜来治疗威尔逊氏病。曲恩汀还可用作肝豆状核变性中铜的螯合剂，环氧树脂的稳定剂，等电聚焦的两性电解质。
T0420	Pentetic Acid Acidum penteticum,Detarex,二乙烯三胺五醋酸,Detapac,DTPA,diethylenetriaminepentaacetic acid	Others	Others
	Pentetic Acid (Detarex) 是一种能够构建磁性吸附剂的化合物，能够去除复杂废水中的重金属及染料。
T1565	Deferiprone 去铁酮,Deferidone,CP20	Others; HCV Protease; Ferroptosis; UGT	Apoptosis; Metabolism; Microbiology/Virology; Others; Proteases/Proteasome
	Deferiprone (Deferidone) 是口服活性铁螯合剂，可研究地中海贫血中的输血性铁过载。
T16503	PF-4191834 PF-04191834	Lipoxygenase	Metabolism
	PF-4191834 是 5-Lipoxygenase (5-LOX) 的非铁螯合和非氧化还原抑制剂，IC50 为 229 nM。 PF-4191834 对 5-LOX 的特异性比 12-LOX 和 15-LOX 高约 300 倍，并且对环氧合酶没有活性。 PF-4191834 可用于炎症和疼痛的研究。
Fr14395	2,2'-Bipyridine
	2,2'-Bipyridine 是一种独特的生物活性天然产物分子支架，常用于许多螯合配体的核心结构。2,2'-Bipyridine 在催化中心的排列中起到桥梁的作用。2,2'-Bipyridine 具有良好的氧化还原稳定性和升糖活性。
T0781	Dimercaprol Dicaptol,二巯丙醇,Dithiopropanol,二巯基丙醇	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Dimercaprol (Dicaptol) 是一种具有抗HIV 活性的重金属中毒解毒剂。
T20346	Salicylaldoxime	Others	Others
	Salicylaldoxime 是一种螯合剂，有时用于分析含有过渡金属离子的样品，它通常与过渡金属离子形成色彩鲜艳的配位络合物。
T20470	Edetic acid Ethylenediaminetetraacetic acid,乙二胺四乙酸,EDTA	Others	Others
	Edetic acid (Ethylenediaminetetraacetic acid) 是 Edetate 的酸形式，是一种具有抗高钙血症和抗凝血特性的螯合剂。它与钙和重金属离子结合后，会形成可溶的稳定复合体，使血清钙水平降低。它也可用作血液样本的抗凝剂，并用于治疗铅中毒。
T8422	DIETHYLDITHIOCARBAMIC ACID COPPER SALT Cupric diethyldithiocarbamate	Others	Others
	DIETHYLDITHIOCARBAMIC ACID COPPER SALT 是一种可用于各种金属、蛋白质和酶实验的螯合剂，也可作为络合剂合成包括杂环化合物在内的各种有机化合物，以及用作铜死亡的诱导剂。
T1482	Ciclopirox 环吡酮,HOE296b,环吡酮胺	ATPase; Ferroptosis; Antibacterial; Autophagy; Antifungal	Apoptosis; Autophagy; Membrane transporter/Ion channel; Microbiology/Virology
	Ciclopirox (HOE296b) 是一种合成的抗真菌剂，可研究浅表真菌病。
T67931	[Tyr3]Octreotate	Others	Others
	[Tyr3]Octreotate 是一个含有8个氨基酸的长肽化合物，是具有共价键DOTA 双功能螯合剂。[Tyr3]Octreotate 与SSR2活性的NETs 的跨膜受体结合，并通过内吞作用主动运输到细胞中，可能会增加所需的双链DNA 断裂，是治疗肿瘤的潜在药物。
T0983L	DL-Penicillamine 3-Sulfanylvaline,DL-青霉胺	Antibiotic	Microbiology/Virology
	DL-Penicillamine (3-Sulfanylvaline) 是一种螯合剂，推荐用于去除威尔逊病患者体内多余的铜。它仅存在于使用或服用该药物的个体中。它是青霉素类抗生素最具特征的降解产物。它被用作抗风湿药和威尔逊病的螯合剂。
T34959	Tropantiol NC100697,NC 100697,TRODAT,NC-100697
	Tropantiol (NC100697) is a chelating agent.
T68816	Zincov
	Zincov is a matrix metalloproteinase inhibitor and chelating agent.
T31236	DDTA
	DDTA is a chelating agent.
T20842	Cyclohexanediamine tetraacetic acid Komplexon IV,Complexon IV
	Cyclohexanediamine tetraacetic acid is a chelating agent.
T19555	S186	Others	Others
	S186 is a kind of sodium salts of calcium-acetylpropylamine phosphonate(APA); and is a new agent of strontium-specific chelating.
T31569	DP-b99 DP-b-99,DP-BAPTA-99,DPb-99,DPBAPTA-99,DP-b 99
	DP-B 99 (DP-B 99, DP-BAPTA-99, DPB-99, DP-BAPTA-99) is a potential chelating agent for the treatment of acute pancreatitis.
T20841	Nitrilotriacetic acid Nitriloacetate,Nitrilotriacetate
	Nitrilotriacetic acid is a chelating agent, complexing agent, metal masking agent.
TNU0612	S-2-(4-Aminobenzyl)-diethylenetriamine pentaacetic acid TFA salt, p-NH2-Bn-DTPA-TFA
	Super-chelating agent & MRI contrast agent
T19207	BFCAs-1	Others	Others
	BFCAs-1 is a polyamine polycarboxylic bifunctional chelating agent (BFCAs) with a broad range of applications in biology, chemistry, medicine and diagnostic imaging.
T30288	BAETA Eedta,BADE,BADA
	BAETA is a calcium selective chelating agent.
T31892	Furildioxime NSC-5055,NSC 5055,NSC5055
	Furildioxime is a Chelating agent for nickel analysis.
T19248	CP 375	Others	Others
	CP 375 is a Fe3+ chelating agent (log K1: 14.50).
T33558	N,N'-Ethylenediamine disuccinic acid L-Ethylenediaminedisuccinic acid,EDDS,EDSS
	N, N'-Ethylenediamine disuccinic acid, as an aminopolycarboxylic acid, can be used as a biodegradable chelating agent similar to EDTA and used on a large scale in numerous applications.
T29677	Aerobactin
	Aerobactin, as a bacterial iron chelating agent (siderophore), can be found in E. coli. It is a virulence factor that can enable E. coli to sequester iron in iron-poor environments.
T33537	Mycobactin P
	Mycobactin P is one of iron(III) chelating compounds produced by most species of Mycobacteria which act as growth factors.
T20471	Edetate Sodium Trilon B,Tetrine
	Edetate Sodium is an agent of a Chelating Agent.
T25727	LiLo
	LiLo is used as a chelating agent for attaching indium-111 to monoclonal antibodies.
T20725	Disodium nitrilotriacetate Disodium hydrogen nitrilotriacetate,Kiresuto NTB
	Disodium nitrilotriacetate is used as a chelating agent, which forms coordination compounds with metal ions such as Fe3+, Cu2+, and Ca2+.
TNU0613	S-2-(4-aminobenzyl)-diethylenetriamine penta-t-butyl acetate
	Super-chelating agent& MRI contrast agent
T34173	p-SCN-Bn-HOPO
	p-SCN-Bn-HOPO is an excellent bifunctional chelating agent for (89)Zr ImmunoPET, with low background, good tumor-organ contrast, and importantly, very low bone uptake for BT474 breast cancer imaging.
T81433	p-NH2-CHX-A"-DTPA
	p-NH2-CHX-A"-DTPA 是双功能螯合剂。
T26041	Ranelic acid
	Ranelic acid is an organic acid capable of chelating metal cations. Strontium ranelate, the strontium salt of Ranelic acid, is utilized to treat osteoporosis and increase bone mineral density.
T20266	Tetrasodium glutamate diacetate
	Tetrasodium glutamate diacetate is a multi-purpose chelating agent and preservative booster. Tetrasodium Glutamate Diacetate serves the same function in formulations as EDTA. Tetrasodium Glutamate Diacetate is made from plant material, readily biodegradab
T81478	Phytochelatin 3 TFA PC 3 TFA
	Phytochelatin 3 (PC 3) TFA，一小分子螯合肽，专用于重金属离子螯合。
T41109	Phytochelatin 2 (PC2)
	Phytochelatin 2, a short plant peptide, serves as an essential metal-binding compound. Phytochelatins are a diverse group of plant compounds that play a crucial role in chelating metals, safeguarding against metal toxicity, and maintaining metal homeostasis.
T79693	PIMPC	GSK-3	PI3K/Akt/mTOR signaling; Stem Cells
	PIMPC为具抗氧化及金属螯合性能之化合物，新型糖原合成酶激酶3（GSK-3）抑制剂，潜在抗阿尔茨海默病作用。
T75335	Ethylenediaminetetraacetic acid dipotassium dihydrate
	Ethylenediaminetetraacetic acid (EDTA) dipotassium dihydrate 是抗凝血剂，可螯合重金属，解除毒性。Ethylenediaminetetraacetic acid dipotassium dihydrate 可破坏染色体、干扰 DNA 修复过程，增加减数分裂交换的发生率。
T69149	L2-b
	L2-b is a bifunctional Aβ-interacting, metal-chelating molecule that modulates ROS production in, and improves survival of neuroblastoma cells incubated in the presence of Aβ along with Copper or Zinc. In cell-free aggregation studies, L2-b inhibits metal-induced Aβ aggregation, and also promotes the dissociation of Ab aggregates in homogenates of human AD brain samples.
T81479	Phytochelatin 3 PC 3
	Phytochelatin 3 (PC 3)是一种具有金属螯合能力的小型肽，主要用途为螯合重金属离子。

化合物

8-Hydroxyquinoline hemisulfate

Cat.No: T7887

Synonym: 8-羟基喹啉硫酸盐,Oxyquinoline sulfate

Target: Others, Antibacterial, Antibiotic

Alizarin Complexone

Cat.No: T19963

Synonym: Alizarin Fluorine Blue,Alizarin-3-methyliminodiacetic acid,茜素络合指示剂

Target: Reverse Transcriptase

Cat.No: T1457

Synonym: ICL 670,CGP-72670,地拉罗司

Target: Others, Ferroptosis, Antibacterial

edetate calcium disodium

Cat.No: T22321

Synonym: EDTA calcium disodium,乙二胺四乙酸二钠钙

Target: Others

Cat.No: T15055

Synonym: MMP-13 Inhibitor

Target: MMP

Cat.No: T8500

Target: OXPHOS, Mitochondrial Metabolism, Autophagy

Cat.No: T19936

Cat.No: T2552

Synonym: DMSA,Dimercaptosuccinic acid,二巯基丁二酸,meso-2,3-dimercaptosuccinic acid,内消旋-2,3-二巯基丁二酸

Target: Others

Cat.No: T65232

Synonym: N-(2-Hydroxyethyl)ethylenediaminetriacetic acid

Target: Others

Cat.No: T21300

Synonym: Triethylenetetramine,Trientine HCl,Trientine,盐酸三乙烯四胺,Triethylene tetramine,TETA,Trien

Target: Others

Cat.No: T0420

Synonym: Acidum penteticum,Detarex,二乙烯三胺五醋酸,Detapac,DTPA,diethylenetriaminepentaacetic acid

Target: Others

Cat.No: T1565

Synonym: 去铁酮,Deferidone,CP20

Target: Others, HCV Protease, Ferroptosis, UGT

Cat.No: T16503

Synonym: PF-04191834

Target: Lipoxygenase

2,2'-Bipyridine

Cat.No: Fr14395

Cat.No: T0781

Synonym: Dicaptol,二巯丙醇,Dithiopropanol,二巯基丙醇

Target: Others, HIV Protease

Salicylaldoxime

Cat.No: T20346

Target: Others

Cat.No: T20470

Synonym: Ethylenediaminetetraacetic acid,乙二胺四乙酸,EDTA

Target: Others

DIETHYLDITHIOCARBAMIC ACID COPPER SALT

Cat.No: T8422

Synonym: Cupric diethyldithiocarbamate

Target: Others

Cat.No: T1482

Synonym: 环吡酮,HOE296b,环吡酮胺

Target: ATPase, Ferroptosis, Antibacterial, Autophagy, Antifungal

[Tyr3]Octreotate

Cat.No: T67931

Target: Others

DL-Penicillamine

Cat.No: T0983L

Synonym: 3-Sulfanylvaline,DL-青霉胺

Target: Antibiotic

Cat.No: T34959

Synonym: NC100697,NC 100697,TRODAT,NC-100697

Cat.No: T68816

Cat.No: T31236

Cyclohexanediamine tetraacetic acid

Cat.No: T20842

Synonym: Komplexon IV,Complexon IV

Cat.No: T19555

Target: Others

Cat.No: T31569

Synonym: DP-b-99,DP-BAPTA-99,DPb-99,DPBAPTA-99,DP-b 99

Nitrilotriacetic acid

Cat.No: T20841

Synonym: Nitriloacetate,Nitrilotriacetate

S-2-(4-Aminobenzyl)-diethylenetriamine pentaacetic acid TFA salt, p-NH2-Bn-DTPA-TFA

Cat.No: TNU0612

Cat.No: T19207

Target: Others

Cat.No: T30288

Synonym: Eedta,BADE,BADA

Cat.No: T31892

Synonym: NSC-5055,NSC 5055,NSC5055

Cat.No: T19248

Target: Others

N,N'-Ethylenediamine disuccinic acid

Cat.No: T33558

Synonym: L-Ethylenediaminedisuccinic acid,EDDS,EDSS

Cat.No: T29677

Cat.No: T33537

Cat.No: T20471

Synonym: Trilon B,Tetrine

Cat.No: T25727

Disodium nitrilotriacetate

Cat.No: T20725

Synonym: Disodium hydrogen nitrilotriacetate,Kiresuto NTB

S-2-(4-aminobenzyl)-diethylenetriamine penta-t-butyl acetate

Cat.No: TNU0613

Cat.No: T34173

p-NH2-CHX-A"-DTPA

Cat.No: T81433

Cat.No: T26041

Tetrasodium glutamate diacetate

Cat.No: T20266

Phytochelatin 3 TFA

Cat.No: T81478

Synonym: PC 3 TFA

Phytochelatin 2 (PC2)

Cat.No: T41109

Cat.No: T79693

Target: GSK-3

Ethylenediaminetetraacetic acid dipotassium dihydrate

Cat.No: T75335

Cat.No: T69149

Phytochelatin 3

Cat.No: T81479

Synonym: PC 3

Cat. No.	Product Name	Target	Signaling Pathways
T8064	Lactobionic acid	Others; Antibacterial	Microbiology/Virology; Others
	Lactobionic acid 是在里海酸奶中的一种仿生酸，化学上由与半乳糖键合的葡萄糖酸组成。它是具有抗氧化、抗菌和保湿特性的乳糖酸。
T20198	Potassium gluconate Kalium-beta,Kalium Gluconate,Kaon elixir,Kaon,Potassium D-gluconate,HSDB 3165,K-Iao	Endogenous Metabolite; Antifungal	Metabolism; Microbiology/Virology
	Potassium gluconate (Potassium D-gluconate) 是一种具有口服活性和螯合性质的氧化型羧酸，具有杀菌活性。
T7892	ATMP	Others	Others
	ATMP 是一种具有螯合特性的膦酸。它是一种阻垢剂。
T0416	Gluconate sodium Sodium D-gluconate,Sodium gluconate,葡萄糖酸钠,D-Gluconic acid sodium salt,D-Gluconate sodium salt	Others; Endogenous Metabolite	Metabolism; Others
	Gluconate sodium (Sodium D-gluconate) 是一种阻垢缓蚀剂。
T7929	L-Aspartic Acid 4-Benzyl Ester	Others	Others
	L-Aspartic Acid 4-Benzyl Ester 是一种螯合剂，与金属离子形成稳定的络合物，已用于研究金属离子对酶活性的影响，以及研究金属离子在基因表达调控中的作用等。
T0983	Penicillamine 青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine	Antibiotic	Microbiology/Virology
	Penicillamine (Artamine) 是一种 penicillin 的代谢降解产物，是一种螯合剂，可作用于威尔逊氏病。
T7963	2,4-Dihydroxypyridine	Others	Others
	2,4-Dihydroxypyridine 是一种吡啶衍生物，作为螯合剂与金属离子结合并形成络合物。它被用作测定各种离子浓度的试剂，如钙、镁和磷酸盐；也用于测量酶催化反应的速率；还用于蛋白质、碳水化合物和其他生物分子的检测和定量。
T10934	D-Gluconic acid Dextronic acid,Glycogenic acid,Pentahydroxycaproic acid,Gluconic acid,D-Gluco-hexonic acid,D-Gluconsaeure,Maltonic acid,葡萄糖酸	Endogenous Metabolite	Metabolism
	D-Gluconic acid (D-Gluco-hexonic acid) 是一种具有杀菌作用和螯合性质的氧化型羧酸。
TN2203	Senecionine N-oxide Senecionine oxide
	Senecionine n-oxide 是千里光寻常型根部培养物中吡咯烷核生物碱生物合成的主要产物，Senecionine N-oxide (Senecionine oxide) 具有抗肿瘤活性，但可诱导肝窦阻塞综合征。Senecionine n-oxide可作为 N-氧化物螯合示踪剂。

天然产物

Lactobionic acid

Cat.No: T8064

Target: Others, Antibacterial

Potassium gluconate

Cat.No: T20198

Synonym: Kalium-beta,Kalium Gluconate,Kaon elixir,Kaon,Potassium D-gluconate,HSDB 3165,K-Iao

Target: Endogenous Metabolite, Antifungal

Cat.No: T7892

Target: Others

Gluconate sodium

Cat.No: T0416

Synonym: Sodium D-gluconate,Sodium gluconate,葡萄糖酸钠,D-Gluconic acid sodium salt,D-Gluconate sodium salt

Target: Others, Endogenous Metabolite

L-Aspartic Acid 4-Benzyl Ester

Cat.No: T7929

Target: Others

Cat.No: T0983

Synonym: 青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine

Target: Antibiotic

2,4-Dihydroxypyridine

Cat.No: T7963

Target: Others

D-Gluconic acid

Cat.No: T10934

Synonym: Dextronic acid,Glycogenic acid,Pentahydroxycaproic acid,Gluconic acid,D-Gluco-hexonic acid,D-Gluconsaeure,Maltonic acid,葡萄糖酸

Target: Endogenous Metabolite

Senecionine N-oxide

Cat.No: TN2203

Synonym: Senecionine oxide

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