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Search Results for " cd45 "

Targets Recommended: Phosphatase PTEN Autophagy

7

抑制剂 & 化合物

19

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T6667	SF1670 PTP CD45 Inhibitor,PTPase CD45 Inhibitor	Phosphatase; PTEN; Autophagy	Autophagy; Metabolism; PI3K/Akt/mTOR signaling
	SF1670 (PTPase CD45 Inhibitor) 是一种特异性 PTEN 抑制剂，IC50 为 2 μM。
T27591	II-B08 II-B 08,FAP1 Inhibitor,II-B-08,LMWPTP Inhibitor,Lyp Inhibitor III,CD45 Inhibitor V
	II-B08 is a cell-permeable SHP2 inhibitor (IC50 = 5.5 µM). II-B08 blocks growth factor stimulated ERK1/2 activation and hematopoietic progenitor proliferation.
T4671	BN82002 CDC25 Phosphatase Inhibitor I	Phosphatase	Metabolism
	BN82002 (CDC25 Phosphatase Inhibitor I) 是一种CDC25 phosphatase 家族的有效的、不可逆的、选择性的泛抑制剂。它显示出比 CD45 酪氨酸磷酸酶高约 20 倍的选择性。
T69969	RWJ-60475
	RWJ-60475 is a novel CD45 phosphatase inhibitor.
T38447	BN82002 hydrochloride
	BN82002 hydrochloride is a potent, selective, and irreversible inhibitor of the CDC25 phosphatase family. It inhibits CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 μM, respectively. Additionally, BN82002 hydrochloride exhibits approximately 20-fold greater selectivity over CD45 tyrosine phosphatase.
T70411	PS372424 HCl
	PS372424 is a specific agonist of human CXCR3. It has been shown to induce phosphorylation of ERK and block CXCL11 induced migration of CD45+ cells to air pouches generated on humanized mice.
T36367	RK-682 (calcium salt)
	Protein tyrosine phosphatases (PTPs) remove phosphate from tyrosine residues of cellular proteins. Reversible phosphorylation catalyzed by the coordinated actions of protein tyrosine kinases and phosphatases is key to the regulation of the signaling events that control cell growth and proliferation, differentiation, and survival or apoptosis, as well as adhesion and motility. RK-682, a bioactive compound originally isolated from the fermentation of Streptomyces sp. 88-682, is an inhibitor of the...

化合物

Cat.No: T6667

Synonym: PTP CD45 Inhibitor,PTPase CD45 Inhibitor

Target: Phosphatase, PTEN, Autophagy

Cat.No: T27591

Synonym: II-B 08,FAP1 Inhibitor,II-B-08,LMWPTP Inhibitor,Lyp Inhibitor III,CD45 Inhibitor V

Cat.No: T4671

Synonym: CDC25 Phosphatase Inhibitor I

Target: Phosphatase

Cat.No: T69969

BN82002 hydrochloride

Cat.No: T38447

Cat.No: T70411

RK-682 (calcium salt)

Cat.No: T36367

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05308	CD45 Protein, Human, Recombinant (aa 1-529, His) GP180,B220,L-CA,protein tyrosine phosphatase, receptor type,...	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPY-05748	CD45 Protein, Human, Recombinant (aa 26-577, His) L-CA,T200,LCA,B220,protein tyrosine phosphatase, receptor ty...	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPJ-00794	CD45 Protein, Mouse, Recombinant (His) CD45,receptor-type tyrosine-protein phosph...	Mouse	Human Cells
	Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. It is a variably glycosylated 180-220 kDa transmembrane protein that is abundantly expressed on all nucleated cells of hematopoietic origin. CD45 has several isofor...
TMPY-04277	CD45 Protein, Mouse, Recombinant (hFc) Cd45,protein tyrosine phosphatase, recepto...	Mouse	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPK-00423	CD45 Protein, Human, Recombinant (His & Avi) CD45R,LY5,EC 3.1.3.48,B220,CD...	Human	HEK293
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts.
TMPY-00711	CD45 Protein, Human, Recombinant (hFc) GP180,L-CA,LY5,T200,protein tyrosine phosphatase, receptor t...	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPK-00424	CD45 Protein, Human, Recombinant (His & Avi), Biotinylated LCA,LY5,EC 3.1.3.48,CD45,L-CA,T200,CD<...	Human	HEK293
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts.
TMPK-00447	CD45 Protein, Human, Recombinant (aa 26-577, hFc) CD45,CD45R,LCA,PTPRC,L-C...	Human	HEK293
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts.
TMPY-03468	CD45 Protein, Mouse, Recombinant (aa 453-1152) loc,Lyt-4,protein tyrosine phosphatase, receptor type, C,T20...	Mouse	Baculovirus-Insect Cells
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPY-03270	CD45 Protein, Mouse, Recombinant (aa 453-1152, His & GST) Ly-5,CD45R,Lyt-4,T200,loc,protein tyrosine...	Mouse	Baculovirus-Insect Cells
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPJ-00808	CD45RA Protein, Human, Recombinant (His) PTPRC,CD45R,CD45,LCA,pro...	Human	Human Cells
	Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. It is a variably glycosylated 180-220 kDa transmembrane protein that is abundantly expressed on all nucleated cells of hematopoietic origin. CD45 has several isofor...
TMPJ-00410	CD45R0 Protein, Human, Recombinant (His) CD45 antigen,L-CA,protein tyrosine phospha...	Human	Human Cells
	Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. It is a variably glycosylated 180-220 kDa transmembrane protein that is abundantly expressed on all nucleated cells of hematopoietic origin. CD45 has several isofor...
TMPH-00266	Galectin-1/LGALS1 Protein, Bovine, Recombinant (His & SUMO)	Bovine	E. coli
	Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
TMPJ-00021	LGALS1 Protein, Human, Recombinant (His) HPL,S-Lac Lectin 1,Lactose-Binding Lectin 1,14 kDa Lectin,Be...	Human	E. coli
	Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domains. Galectin-1 can binds LGALS3BP and interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Galectin-1 may act as an autocrine negative growth factor which regulates apoptosis, cell proliferation and cell differentiation. In addition, Galectin-1 plays improtant roles in immunosuppress...
TMPJ-00020	IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated 白介素,Eosinophil differentiation factor,B-cell differentiation...	Human	Human Cells
	IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cells and eosinophils. Relative to B cells, IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells. In addition, it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functi...
TMPY-02102	Galectin-1 Protein, Mouse, Recombinant L-14.5,Galbp,AA410090,lectin, galactoside-binding, soluble, ...	Mouse	E. coli
	Galectin-1 (Gal-1, GAL1), is a member of the galectins, a family of animal lectins ranging from Caenorhabditis elegans to humans, which is defined by their affinity for beta-galactosides and by significant sequence similarity in the carbohydrate-binding site. It is a homodimer with a subunit molecular mass of 14.5 kDa, which contains six cysteine residues per subunit. The cysteine residues should be in a free state to maintain a molecular structure that is capable of showing lectin activity. Thi...
TMPY-06685	Galectin-1 Protein, Human, Recombinant (His) GBP,GAL1,lectin, galactoside-binding, soluble, 1,Galectin-1	Human	E. coli
	Galectin-1 (Gal-1, GAL1), is a member of the galectins, a family of animal lectins ranging from Caenorhabditis elegans to humans, which is defined by their affinity for beta-galactosides and by significant sequence similarity in the carbohydrate-binding site. It is a homodimer with a subunit molecular mass of 14.5 kDa, which contains six cysteine residues per subunit. The cysteine residues should be in a free state to maintain a molecular structure that is capable of showing lectin activity. Thi...
TMPY-03131	Galectin-1 Protein, Rat, Recombinant lectin, galactoside-binding, soluble, 1	Rat	E. coli
	Galectin-1 (Gal-1, GAL1), is a member of the galectins, a family of animal lectins ranging from Caenorhabditis elegans to humans, which is defined by their affinity for beta-galactosides and by significant sequence similarity in the carbohydrate-binding site. It is a homodimer with a subunit molecular mass of 14.5 kDa, which contains six cysteine residues per subunit. The cysteine residues should be in a free state to maintain a molecular structure that is capable of showing lectin activity. Thi...
TMPY-00976	Galectin-1 Protein, Human, Recombinant GBP,Galectin-1,lectin, galactoside-binding, soluble, 1,GAL1	Human	E. coli
	Galectin-1 (Gal-1, GAL1), is a member of the galectins, a family of animal lectins ranging from Caenorhabditis elegans to humans, which is defined by their affinity for beta-galactosides and by significant sequence similarity in the carbohydrate-binding site. It is a homodimer with a subunit molecular mass of 14.5 kDa, which contains six cysteine residues per subunit. The cysteine residues should be in a free state to maintain a molecular structure that is capable of showing lectin activity. Thi...

重组蛋白

CD45 Protein, Human, Recombinant (aa 1-529, His)

Cat.No: TMPY-05308

Species: Human

Expression System: HEK293

CD45 Protein, Human, Recombinant (aa 26-577, His)

Cat.No: TMPY-05748

Species: Human

Expression System: HEK293

CD45 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00794

Species: Mouse

Expression System: Human Cells

CD45 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-04277

Species: Mouse

Expression System: HEK293

CD45 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00423

Species: Human

Expression System: HEK293

CD45 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00711

Species: Human

Expression System: HEK293

CD45 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00424

Species: Human

Expression System: HEK293

CD45 Protein, Human, Recombinant (aa 26-577, hFc)

Cat.No: TMPK-00447

Species: Human

Expression System: HEK293

CD45 Protein, Mouse, Recombinant (aa 453-1152)

Cat.No: TMPY-03468

Species: Mouse

Expression System: Baculovirus-Insect Cells

CD45 Protein, Mouse, Recombinant (aa 453-1152, His & GST)

Cat.No: TMPY-03270

Species: Mouse

Expression System: Baculovirus-Insect Cells

CD45RA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00808

Species: Human

Expression System: Human Cells

CD45R0 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00410

Species: Human

Expression System: Human Cells

Galectin-1/LGALS1 Protein, Bovine, Recombinant (His & SUMO)

Cat.No: TMPH-00266

Species: Bovine

Expression System: E. coli

LGALS1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00021

Species: Human

Expression System: E. coli

IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00020

Species: Human

Expression System: Human Cells

Galectin-1 Protein, Mouse, Recombinant

Cat.No: TMPY-02102

Species: Mouse

Expression System: E. coli

Galectin-1 Protein, Human, Recombinant (His)

Cat.No: TMPY-06685

Species: Human

Expression System: E. coli

Galectin-1 Protein, Rat, Recombinant

Cat.No: TMPY-03131

Species: Rat

Expression System: E. coli

Galectin-1 Protein, Human, Recombinant

Cat.No: TMPY-00976

Species: Human

Expression System: E. coli

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