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Search Results for " betulinic acid "

10

抑制剂 & 化合物

6

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T37038	Betulinic Acid propargyl ester
	Betulinic acid propargyl ester is a pentacyclic lupane triterpene and alkyne derivative of betulinic acid .1,2It has been used in click chemistry reactions for the synthesis of cytotoxic anticancer betulinic acid derivatives.
T40328	Betulinic acid derivative-1
	Betulinic acid derivative-1 demonstrates potent inhibition of osteoclast (OC) differentiation, achieving an IC50 value of 1.86 μM.
T131503	Betulinic acid (Mairin; Gratiolone; Platanol)
	Betulinic acid (Mairin; Gratiolone; Platanol) 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131503。
T0028	Gamibetal 3-Hydroxy-GABA,4-氨基-3-羟基丁酸,4-Amino-3-hydroxybutyric Acid	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Gamibetal (4-Amino-3-hydroxybutyric Acid) 是 γ-氨基-β-羟基丁酸，对癫痫具有潜在的研究价值。
T16368	NVX-207	Others	Others
	NVX-207 is a derivative of betulinic acid. It has anti-cancer activity.
T35678	2,3-Indolobetulinic glycine amide
	2,3-Indolobetulinic glycine amide is a pentacyclic triterpene and derivative of betulinic acid .1It has been used in the synthesis of betulinic acid derivatives with anticancer activity. 1.Kumar, V., Rani, N., Aggarwal, P., et al.Synthesis and cytotoxic activity of heterocyclic ring-substituted betulinic acid derivativesBioorg. Med. Chem. Lett.18(18)5058-5062(2008)
T32963	LupGG Lup-20(29)-en-28-oic-3-O-beta-glucopyranosyl(2-1)-O-beta-glucopyranoside
	Lup-20(29)-en-28-oic-3-O-beta-glucopyranosyl(2-1)-O-beta-glucopyranoside is a betulinic acid glycoside from Schefflera venulosa.
T74513	RPR103611
	RPR103611，一个桦木酸衍生物，作为HIV-1入侵抑制剂表现出高效性，其对CCR5（热带）病毒YU2、CXCR4（热带）病毒NL4-3及双热带病毒89.6的IC50分别达到80、0.27和0.17。
T35693	N-(2-Azidoethyl)betulonamide
	N-(2-Azidoethyl)betulonamide is a pentacyclic triterpenoid, a derivative of betulonic acid , and an intermediate in the synthesis of betulonic acid derivatives within vitrocancer cell cytotoxicity.1 1.Suman, P., Patel, A., Solano, L., et al.Synthesis and cytotoxicity of Baylis-Hillman template derived betulinic acid-triazole conjugatesTetrahedron73(29)4214-4226(2017)
T79464	RORγ antagonist 1	ROR	Metabolism
	RORγ antagonist1 (化合物22) 作为RORγ的有效拮抗剂 (KD=0.18 μM)，在HPAF-II胰腺癌异种移植模型中显示出了抗增殖性能。该化合物通过抑制RAS/MAPK和AKT/mTORC1通路，并引发caspase依赖的细胞凋亡(apoptosis)机制，从而在胰腺癌细胞中发挥作用。

化合物

Betulinic Acid propargyl ester

Cat.No: T37038

Betulinic acid derivative-1

Cat.No: T40328

Betulinic acid (Mairin; Gratiolone; Platanol)

Cat.No: T131503

Cat.No: T0028

Synonym: 3-Hydroxy-GABA,4-氨基-3-羟基丁酸,4-Amino-3-hydroxybutyric Acid

Target: HIV Protease

Cat.No: T16368

Target: Others

2,3-Indolobetulinic glycine amide

Cat.No: T35678

Cat.No: T32963

Synonym: Lup-20(29)-en-28-oic-3-O-beta-glucopyranosyl(2-1)-O-beta-glucopyranoside

Cat.No: T74513

N-(2-Azidoethyl)betulonamide

Cat.No: T35693

RORγ antagonist 1

Cat.No: T79464

Target: ROR

Cat. No.	Product Name	Target	Signaling Pathways
T2830	Betulinic acid 白桦脂酸,桦木酸,ALS-357,Lupatic acid,Betulic acid	Apoptosis; Mitophagy; NF-κB; HIV Protease; Topoisomerase; Endogenous Metabolite; Aminopeptidase; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Betulinic acid (ALS-357) 是从白桦树皮中分离出来的一种五环三萜类天然产物，是真核细胞拓扑异构酶 I 的抑制剂，IC50值为 5 μM，具有抗逆转录病毒、抗疟疾、抗癌和抗炎特性。
TN5987	Betulinic acid palmitate
	Betulinic acid palmitate 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5987，CAS号为 19833-15-9。
TN1442	Betulinic acid methyl ester	Antifection	Microbiology/Virology
	Betulinic acid methyl ester showed antiplasmodial activity against chloroquine-resistant Plasmodium falciparum parasites in vitro.It also inhibited B16 2F2 cell proliferation by induction of apoptosis.
T3121	Betulin Trochol,betulinic alcohol,betuline,betulinol,桦木醇,Betulol,白桦脂醇	Apoptosis; Endogenous Metabolite; Lipid; Fatty Acid Synthase	Apoptosis; Metabolism
	Betulin (betulinol) 是从桦树树皮中分离出来的一种天然三萜，是 SREBP 抑制剂。
TN4449	Longistylin C	Antifection	Microbiology/Virology
	Longistylin A and longistylin C show some cytotoxic effects, with IC(50) values of 0.7-14.7 microM against the range of cancer cell lines. Longistylin A and longistylin C, and betulinic acid show a moderately high in vitro activity against the chloroquine
T3930	Taraxerol acetate 醋酸蒲公英霜,Taraxeryl acetate	Phosphatase; HSV	Metabolism; Microbiology/Virology
	Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol. A. roxburghiana has antidiabetic activity, could be attributed due to PTP

天然产物

Betulinic acid

Cat.No: T2830

Synonym: 白桦脂酸,桦木酸,ALS-357,Lupatic acid,Betulic acid

Target: Apoptosis, Mitophagy, NF-κB, HIV Protease, Topoisomerase, Endogenous Metabolite, Aminopeptidase, Autophagy

Betulinic acid palmitate

Cat.No: TN5987

Betulinic acid methyl ester

Cat.No: TN1442

Target: Antifection

Cat.No: T3121

Synonym: Trochol,betulinic alcohol,betuline,betulinol,桦木醇,Betulol,白桦脂醇

Target: Apoptosis, Endogenous Metabolite, Lipid, Fatty Acid Synthase

Cat.No: TN4449

Target: Antifection

Taraxerol acetate

Cat.No: T3930

Synonym: 醋酸蒲公英霜,Taraxeryl acetate

Target: Phosphatase, HSV

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