7
340
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T78274 |
Omburtamab
|
||
Omburtamab是一款针对CD276(亦称为B7-H3)的单克隆抗体,后者为在人类实体肿瘤中表达的B7/CD28免疫球蛋白家族成员。此抗体能够结合肿瘤组织,被应用于多种癌症的研究中。 | |||
T77909 |
Mirzotamab
|
||
Mirzotamab clezutoclax(ABBV-155)是一种IgG1κ型靶向CD276/B7-H3的抗体偶联物(ADC),通过与BCL抑制剂Clezutoclax结合而构成。该化合物用于参与针对复发/难治性实体瘤的紫杉烷相关研究。 | |||
T7206L |
2-Iminobiotin hydrobromide
2-亚氨基生物素,Guanidinobiotin,2-亚氨基生物素盐酸盐 |
NOS; NO Synthase | Immunology/Inflammation |
2-Iminobiotin hydrobromide (Guanidinobiotin) 是生物素 (维生素 H 或 B7) 类似物。它是一种可逆的 NO 合酶抑制剂,可作用于小鼠 iNOS(Ki:21.8 μM)和大鼠 n-cNOS(Ki:37.5 μM)。它和低温环境均可以保护人类神经细胞,使其免受缺氧诱导的细胞损伤。 | |||
T75292 | Biotin sodium | ||
Biotin (Vitamin B7) sodium 是一种水溶性维生素 B,是人体五种羧化酶的辅酶,参与脂肪酸、异亮氨酸和缬氨酸的合成,并参与糖异生。Biotin sodium 是细胞生长、脂肪酸产生以及脂肪和氨基酸代谢的必需物质。 | |||
T78107 |
Reltecimod TFA
AB-103 TFA |
||
Reltecimod (AB-103) TFA 是一款针对 T 细胞特异性表面糖蛋白CD28(TP44) 的拮抗剂。该化合物能够有效抵御各类细菌感染、细菌产生的外毒素和内毒素,以及电离辐射。其通过特异性目标定位并调节 CD28/B7-2 共刺激通路以减弱炎症反应,但并不完全抑制该通路。Reltecimod TFA 主要用于坏死性软组织感染(NSTIs)的研究。 | |||
T7206 |
2-Iminobiotin
2-IMINOBIOTIN HYDROBROMIDE,2-亚氨基生物素,Guanidinobiotin |
NOS; NO Synthase | Immunology/Inflammation |
2-Iminobiotin (Guanidinobiotin) 是一种生物素 (维生素 H 或 B7) 类似物。它是一种可逆的 NO 合酶抑制剂,能够作用于小鼠 iNOS(Ki:21.8 μM)及大鼠 n-cNOS(Ki:37.5 μM)。它和低温环境均可以保护人类神经细胞,使其免受缺氧诱导的细胞损伤。 | |||
T36137 |
Biotin (S)-sulfoxide
|
||
Biotin (S)-sulfoxide is an inactive metabolite of the coenzyme biotin .1,2It has also been found inE. coliand is reduced by the biotin sulfoxide reduction system as a source of biotin.3 1.Denkel, L.A., Rhen, M., and Bange, F.-C.Biotin sulfoxide reductase contributes to oxidative stress tolerance and virulence in Salmonella enterica serovar TyphimuriumMicrobiology (Reading)159(Pt 7)1447-1458(2013) 2.Carling, R.S., and Turner, C.Methods for assessment of biotin (Vitamin B7)Laboratory assessment of... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02031 |
B7-H3 Protein, Human, Recombinant (His)
CD276 molecule,B7-H3,4Ig-B7-H3, |
Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1. | |||
TMPY-04262 |
B7-H3 Protein, Human, Recombinant (His), Biotinylated
B7H3,4Ig-B7-H3,CD276 molecule, |
Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1. | |||
TMPY-05641 |
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated
4Ig-B7-H3,B7-H3,B7H3,CD2... |
Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 49.8 kDa and the accession number is Q5ZPR3. | |||
TMPY-05016 |
HHLA2 Protein, Human, Recombinant (His)
HERV-H LTR-associating 2,HHLA2,B7... |
Human | HEK293 Cells |
HHLA2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.4 kDa and the accession number is Q9UM44-1. | |||
TMPY-01180 |
CD86 Protein, Human, Recombinant (His)
CD86 antigen,B70,B7.2,B7... |
Human | HEK293 Cells |
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3. | |||
TMPK-00653 |
B7-2 Protein, Cynomolgus, Recombinant (His)
B72,MGC34413,LAB72,B... |
Cynomolgus | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His... | |||
TMPK-00881 |
B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated
LAB72,B7-2,B7-<... |
Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-00882 |
B7-2 Protein, Human, Recombinant (hFc)
B7-2,FUN-1,B7-2 antigen,... |
Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag.... | |||
TMPJ-00959 |
B7-2 Protein, Rabbit, Recombinant (His)
CD86,T-lymphocyte activation antigen CD86,Activation B7<... |
Rabbit | HEK293 Cells |
B7-2 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-70 KDa and the accession number is P42071. | |||
TMPJ-00632 |
B7-2 Protein, Cynomolgus, Recombinant (hFc)
T-lymphocyte activation antigen CD86 isoform 1,Activation |
Cynomolgus | HEK293 Cells |
B7-2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-100 KDa and the accession number is G7NXR4. | |||
TMPK-00880 |
B7-2 Protein, Human, Recombinant (His & Avi)
B70,B7-2 antigen,B7-... |
Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. B7-2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPY-04957 |
PD-L2 Protein, Human, Recombinant (His), Biotinylated
B7DC,Btdc,B7-DC,bA574F11.2,PDL |
Human | HEK293 Cells |
PD-L2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1. | |||
TMPY-04346 |
PD-L2 Protein, Human, Recombinant (His)
PD-L2,B7-DC,CD273,Btdc,PDCD1L... |
Human | HEK293 Cells |
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1. | |||
TMPY-05827 |
PD-L2 Protein, Human, Recombinant (mFc)
PDCD1L2,bA574F11.2,Btdc,B7-DC,PD-... |
Human | HEK293 Cells |
PD-L2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 48.93 kDa and the accession number is Q9BQ51-1. | |||
TMPJ-00641 |
B7-2 Protein, Rhesus macaque, Recombinant (His)
Activation B7-2 antigen,T-lymphocyte activ... |
Rhesus | HEK293 Cells |
B7-2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-90 KDa and the accession number is H9ZFI8. | |||
TMPY-06581 |
B7-H3 Protein, Human, Recombinant (isoform 2, His)
CD276 molecule,B7H3,B7RP-2 |
Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (isoform 2, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.52 kDa and the accession number is Q5ZPR3-2. | |||
TMPJ-00556 |
B7-2 Protein, Human, Recombinant (His)
CD86,T-Lymphocyte Activation Antigen CD86,Activation B7<... |
Human | HEK293 Cells |
B7-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 57-66 KDa and the accession number is AAH40261.1. | |||
TMPJ-00555 |
B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated
Activation B7-2 Antigen,FUN-1,CTLA-4 Count... |
Human | HEK293 Cells |
B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 55-80 KDa and the accession number is AAH40261.1. | |||
TMPY-05279 |
B7-H3 Protein, Human, Recombinant (hFc), Biotinylated
B7RP-2,B7-H3,CD276 molec... |
Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q5ZPR3-1. | |||
TMPK-01263 |
B7-H7 Protein, Cynomolgus, Recombinant (His)
B7H7,B7-H7,HHLA2,B7 Homo... |
Cynomolgus | HEK293 Cells |
B7-H7, also known as HHLA2 (HERV-H LTR-associating 2), is a member of the B7 family of immune regulatory proteins.Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. | |||
TMPY-00643 |
B7-H3 Protein, Human, Recombinant (hFc)
B7RP-2,B7H3,B7-H3,4Ig- |
Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.3 kDa and the accession number is Q5ZPR3-1. | |||
TMPY-06177 |
HHLA2 Protein, Human, Recombinant (His), Biotinylated
B7-H7,B7H7,HHLA2,HERV-H LTR-assoc... |
Human | HEK293 Cells |
HHLA2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.4 kDa and the accession number is Q9UM44-1. | |||
TMPY-00030 |
HHLA2 Protein, Human, Recombinant (hFc)
HERV-H LTR-associating 2,B7H7,B7-... |
Human | HEK293 Cells |
HHLA2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63.7 kDa and the accession number is Q9UM44-1. | |||
TMPY-01206 |
CD86 Protein, Mouse, Recombinant (His)
Cd28l2,CLS1,Ly58,Ly-58,B7,MB7... |
Mouse | HEK293 Cells |
CD86 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is P42082-1. | |||
TMPY-06880 |
CD86 Protein, Human, Recombinant (His & Avi), Biotinylated
B7-2,CD28LG2,B7... |
Human | HEK293 Cells |
CD86 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.42 kDa and the accession number is NP_008820.4. | |||
TMPY-05390 |
CD86 Protein, Human, Recombinant (hFc)
B7.2,LAB72,CD86 antigen,... |
Human | HEK293 Cells |
CD86 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.9 kDa and the accession number is A0A0X9R4E0. | |||
TMPY-05386 |
CD86 Protein, Mouse, Recombinant (hFc)
Ly58,B7.2,ETC-1,B70,TS/A-2 |
Mouse | HEK293 Cells |
CD86 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52 kDa and the accession number is P42082-1. | |||
TMPY-05133 |
CD86 Protein, Mouse, Recombinant (His), Biotinylated
Ly-58,ETC-1,B70,MB7,TS/A-2,Cd... |
Mouse | HEK293 Cells |
CD86 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is P42082-1. | |||
TMPY-05246 |
CD86 Protein, Human, Recombinant (His), Biotinylated
CD28LG2,B70,B7.2 |
Human | HEK293 Cells |
CD86 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P42081-3. | |||
TMPY-02436 |
PD-L2 Protein, Mouse, Recombinant (hFc)
F730015O22Rik,Btdc,PD-L2,programm... |
Mouse | HEK293 Cells |
PD-L2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q9WUL5. | |||
TMPY-02352 |
PD-L2 Protein, Mouse, Recombinant (His)
programmed cell death 1 ligand 2,Btdc,F730015O2... |
Mouse | HEK293 Cells |
PD-L2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9WUL5. | |||
TMPY-05282 |
PD-L2 Protein, Mouse, Recombinant (His), Biotinylated
PD-L2,programmed cell death 1 ligand 2, |
Mouse | HEK293 Cells |
PD-L2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9WUL5. | |||
TMPK-00166 |
PD-L2 Protein, Human, Recombinant (His & Avi)
PDL2,Btdc,Butyrophilin B7-DC,PDCD1LG2<... |
Human | HEK293 Cells |
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. PD-L2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.3 kDa and the accession nu... | |||
TMPK-01290 |
PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His)
B7DC,PDL2,CD273, PDCD1 ligand |
Cynomolgus | HEK293 Cells |
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 23.73 kDa and the acces... | |||
TMPY-00120 |
PD-L2 Protein, Human, Recombinant (hFc)
Btdc,B7-DC,programmed cell death 1 ligand 2 |
Human | HEK293 Cells |
PD-L2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.3 kDa and the accession number is Q9BQ51-1. | |||
TMPY-05613 |
PD-L2 Protein, Human, Recombinant (His & Avi), Biotinylated
bA574F11.2,programmed cell death 1 ligand 2 |
Human | HEK293 Cells |
PD-L2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25.8 kDa and the accession number is Q9BQ51-1. | |||
TMPY-06281 |
PD-L2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
bA574F11.2,B7DC,B7-DC,PDCD1L2... |
Human | HEK293 Cells |
PD-L2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 51.09 kDa and the accession number is Q9BQ51-1. | |||
TMPY-01648 |
TREML2 Protein, Human, Recombinant (His)
TLT2,dJ238O23.1,triggering recept... |
Human | HEK293 Cells |
Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like) domain. TREML2 is detected in cultured B cells, T cell leukemia and monocyte leukemia. TREML2 is expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation. TREML2 is a cell surface receptor that may play a role in the innate and adaptive immune respons... | |||
TMPK-01016 |
B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled
B7H3, UNQ309,PRO352,PSEC0249,... |
Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular w... | |||
TMPK-01017 |
B7-H3 Protein, Human, Recombinant (aa 29-245, hFc)
B7H3,B7-H3,B7 homolog 3,PSEC0... |
Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (aa 29-245, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weig... | |||
TMPK-01018 |
B7-H3 Protein, Human, Recombinant (aa 29-245, His)
PRO352,B7H3, UNQ309,PSEC0249,CD |
Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (aa 29-245, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weig... | |||
TMPK-01176 |
CD28 Protein, Canine, Recombinant (His)
CD28 antigen (Tp44),MGC138290,CD2... |
Canine | HEK293 Cells |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. CD28 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 16.7 kDa and the accession number is Q9GKP3. | |||
TMPK-01177 |
CD28 Protein, Canine, Recombinant (mFc)
CD28 molecule,CD28 antigen (Tp44),CD2<... |
Canine | HEK293 Cells |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. CD28 Protein, Canine, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 41.6 kDa and the accession number is Q9GKP3. | |||
TMPJ-00958 |
B7-1 Protein, Rabbit, Recombinant (His)
Activation B7-1 antigen,T-lymphocyte activation ant... |
Rabbit | HEK293 Cells |
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can ... | |||
TMPK-00111 |
CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi), Biotinylated
CD28 antigen (Tp44),CD28 molecule,CD2<... |
Human,Cynomolgus,Rhesus | HEK293 Cells |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 18.2 k... | |||
TMPJ-00176 |
B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
B7H4T-cell costimulatory molecule B7x,FLJ<... |
Human | HEK293 Cells |
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H4 consists of a 235 amino acid (aa) extracellular domain (ECD) with two Ig-like V-type domains, a 21 aa transmembrane segment, and a 2 aa cytoplasmic tail. It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine ... | |||
TMPJ-00630 |
B7-1 Protein, Cynomolgus, Recombinant (hFc)
B7,CD80,T-lymphocyte activation antigen CD80,Activa... |
Cynomolgus | HEK293 Cells |
Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.CD80 plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the ... | |||
TMPK-00110 |
CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi)
CD28 molecule,MGC138290,CD28,CD |
Human,Cynomolgus,Rhesus | HEK293 Cells |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 18.2 kDa and the acc... | |||
TMPY-00004 |
CD28 Protein, Rat, Recombinant (hFc)
CD28 molecule |
Rat | HEK293 Cells |
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell r... | |||
TMPJ-00353 |
ILDR2 Protein, Human, Recombinant (His)
Angulin-3,immunoglobulin-like domain containing receptor |
Human | HEK293 Cells |
ILDR2 is a member of the B7-like family of proteins that regulate T cell activity, is also a known endoplasmic reticulum molecule that regulates lipid homeostasis. The human ILDR2 lumenal domain shares a 99% and 98% homology with the mouse and rat respectively. The human gene encoding ILDR2 is located in a region on Chr1q23–25 that has been associated with type 2 diabetes. ILDR2 plays critical roles in hepatic clearance of lipoproteins and in lipid homeostasis. ILDR2 regulates human dendritic ce... | |||
------------------------ 更多 ------------------------ |