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28
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T26629 |
Angstrom6
A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide |
PAI-1 | Metabolism |
Angstrom6 (A-6 peptide) 是一种从单链尿激酶纤溶酶原激活剂(scuPA)中提取的 8 肽,它能干扰 uPA/uPAR 级联反应并抑制下游效应。Angstrom6 具有抗肿瘤活性,能通过与 CD44 结合并调节 CD44 介导的细胞信号传导,抑制肿瘤细胞的迁移、侵袭和转移。 | |||
TP2425 |
Cucumarioside A6-2
|
||
Cucumarioside A6-2 is a triterpene glycoside. | |||
T125557 | Calystegine A6 | ||
Calystegine A6 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125557。 | |||
T130031 |
Iturin A6
|
||
Iturin A6 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T130031。 | |||
T13047 |
Synta66
|
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Synta66 是一种钙池操纵钙离子通道 Orai 抑制剂,用于神经系统疾病的研究。 | |||
T62568 |
IXA6
|
IRE1 | Cell Cycle/Checkpoint |
IXA6 是一种新型的IRE1/XBP1s激动剂,具有潜在的血管保护活性,可激活 IRE1-XBP1s 信号传导和 XBP1s 转录反应,可用于研究帕金森病和阿尔茨海默病等神经退行性疾病。 | |||
T2418 |
A66
|
PI3K | PI3K/Akt/mTOR signaling |
A66 是高效的、特异性的、选择性 p110α 抑制剂,其 IC50=32 nM。 | |||
TQ0076 |
KIRA6
|
IRE1 | Cell Cycle/Checkpoint |
KIRA6 是一种 IRE1α RNase 激酶的有效抑制剂,IC50为0.6 µM。它可以触发细胞凋亡反应。 | |||
T61393 | IAA65 | ||
IAA65 是一种有效的 T 型钙通道抑制剂 (T-type calcium channel),IC50值为 18.9 μM。IAA65 可用于癫痫研究。 | |||
T29511 |
A61603
|
||
A61603 is an alpha-1A adrenergic receptor. | |||
T61815 | AL-GDa62 | ||
AL-GDa62是一种潜在的治疗胃癌的合成致死疗法。该化合物对MCF10A-WT(野生型)和MCF10A-CDH1-/-(突变型)同基因乳腺上皮细胞的EC50分别为3.2 μM和2 μM。 | |||
T83034 |
Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6)
|
||
Anti-Mouse TCR V gamma 2 Antibody是一种针对小鼠TCR V gamma 2的IgG类型的抗体抑制剂,其宿主为Armenian Hamster。 | |||
T36833 |
A6770
|
||
A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.1It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50= <0.01 μM), an effect that is reduced in the presence of vitamin B6(EC50= <100 μM). 1.Ohtoyo, M., Tamura, M., Machinaga, N., et al.Scintillation proximity assay to detect the changes in cellular dihydrosphingosine 1-phosphate levelsLipids51(10)1207-1216(2016) | |||
T63116 |
TXA6101
|
||
TXA6101 是一种细菌蛋白 FtsZ (丝状温度敏感蛋白 Z) 抑制剂。TXA6101 能够抑制细菌的分裂,对表达 G193D 或 G196S 突变体 FtsZ 的 MRSA 分离株的抗菌活性 MIC 值都为 1 μg/mL,对 TXA707 抗性 FtsZ 突变体保留显着活性。TXA6101 能用做潜在的抵抗革兰氏阴性菌感染方法。 | |||
T83732 |
Tat-CBD3A6K TFA
|
||
Tat-CBD3A6K是一种肽类化合物,为N型电压门控钙通道Cav2.2以及collapsin response mediator protein 2 (CRMP2) 蛋白-蛋白相互作用抑制剂Tat-CBD3的衍生物。Tat-CBD3A6K (10 mg/kg) 能够阻止由d4T (stavudine)引发的大鼠抗逆转录病毒神经病痛模型中爪撤回阈值的下降,并减少同一大鼠分离的背根神经节(DRG)神经元的动作电位数量。通过硬膜途径给予Tat-CBD3A6K (30 µM/animal) 能够减少由萜类生物碱辣椒素引发的大鼠硬脑膜血流增加。 | |||
T83498 |
[D-Phe2,D-Ala6]-LH-RH
Wy 18185 |
||
[D-Phe2,D-Ala6]-LH-RH 为有效LH-RH拮抗剂,展现了显著的抗LH/FSH-RH及抗排卵活性。 | |||
T76593 |
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)
|
||
'(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)' 为一种GnRH类似物,主要用于诱导养殖鱼类排卵和/或产卵。 | |||
T26432 |
A68930
A 68930,A70108,A-68930,A 70108,A-70108 |
||
A 68930 is a dopamine D-1 receptor antagonist. A 68930 inhibits NLRP3 inflammasome activity. | |||
T28786 |
SJA6017
SJA-6017,Calpain Inhibitor VI,Calpain-In-4,SJA 6017,Calpain Inhibitor 4 |
||
SJA6017 is a inhibitor of calpain-1 (IC50 = 7.5 nM) and calpain-2 ( IC50 = 78 nM). SJA6017 also inhibits cathepsins B (IC50s = 15 nM) and cathepsins L (IC50s = 1.6 nM). SJA6017 reduces apoptotic cell death, preserves spinal cord tissue and improves functi | |||
T71351 | STAT3-IN-A69 | ||
STAT3-IN-A69 is an inhibitor targeting the DNA-binding domain of STAT3, suppressing tumor growth, metastasis and STAT3 target gene expression in vivo. | |||
T76351 | [D-Ala6]-LH-RH | ||
[D-Ala6]-LH-RH,一种黄体激素释放激素(LHRH)模拟物,充当GnRH受体的激动剂。 | |||
T28467 |
PSMA617-TCMC TFA
PSMA617-TCMC TFA salt,PSMA617-analog, PSMA617-derivative with TCMC,PSMA-617-TCMC |
||
PSMA617-TCMC is a derivative of PSMA-617 with structure modification, in which the caroboxy groups in DOTA ring is replaced by TCMC macrocycle. PSMA-617 is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer. | |||
T79138 |
Antitumor agent-100 hydrochloride
|
Molecular Glues | PROTAC |
Antitumor agent-100 hydrochloride (compound A6) 作为细胞凋亡诱导剂和分子胶,展现了显著的抗肿瘤活性。 | |||
T75017 | PROTAC HDAC6 degrader 1 | ||
PROTACHDAC6 degrader (Compound A6) 为有效且选择性的PROTACHDAC6降解剂,具有3.5 nM的DC50。在髓系白血病细胞系中,通过诱导凋亡(apoptosis)表现出抗增殖活性。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5S2204 |
Sibiricose A6
西伯利亚远志糖A6 |
Antioxidant | oxidation-reduction |
Sibiricose A6 是一种寡糖酯,分离自Polygalae Radix,具有抗氧化作用。 | |||
T82319 |
Ginsenoside Ra6
Ginsenoside IV |
||
Ginsenoside Ra6 (Ginsenoside IV)为一种从人参根部提取的二醇型人参皂苷。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01041 |
Carboxypeptidase A6 Protein, Human, Recombinant (His & SUMO)
CPAH,CPA6,Carboxypeptidase A6 |
Human | E. coli |
May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II. Releases a C-terminal amino acid, with preference for large hydrophobic C-terminal amino acids and shows only very weak activity toward small amino acids and histidine. Carboxypeptidase A6 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular w... | |||
TMPY-02592 |
Annexin VI/ANXA6 Protein, Human, Recombinant (His)
ANX6,annexin A6,CBP68 |
Human | E. coli |
Annexin A6, also known as ANXA6 or ANXAⅥ, belongs to a family of Ca2+-dependent membrane and phospholipid binding proteins. Members of this family have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 6 is phosphorylated in vivo associated with cell growth. Annexin 6 was not phosphorylated in quiescent cells, but was phosphorylated on serine and to a lesser extent threonine, several hours following cell stimulation. Experiment has revealed the presenc... | |||
TMPY-01789 |
EphA6 Protein, Mouse, Recombinant (hFc)
m-ehk2,EPH receptor A6,Ehk2,Hek12 |
Mouse | HEK293 Cells |
EphA6 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85 kDa and the accession number is G1K381. | |||
TMPY-01326 |
EphA6 Protein, Mouse, Recombinant (His)
EPH receptor A6,Ehk2,m-ehk2,Hek12 |
Mouse | HEK293 Cells |
EphA6 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.5 kDa and the accession number is G1K381. | |||
TMPY-01094 |
S100A6 Protein, Mouse, Recombinant
2A9,PRA,5B10,S100 calcium binding protein A6,Cacy,C... |
Mouse | E. coli |
S100A6 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 10 kDa and the accession number is P14069. | |||
TMPY-01822 |
PTK9 Protein, Human, Recombinant (His & GST)
PTK9,MGC41876,A6,MGC23788,twinfilin actin binding p... |
Human | E. coli |
PTK9 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 57 kDa and the accession number is Q12792-4. | |||
TMPY-00912 |
S100A6 Protein, Human, Recombinant
5B10,PRA,S100 calcium binding protein A6,CACY,CABP,... |
Human | E. coli |
S100A6 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 10.2 kDa and the accession number is P06703. | |||
TMPY-01823 |
PTK9 Protein, Human, Recombinant
MGC41876,twinfilin actin binding protein 1,A6,MGC23... |
Human | E. coli |
PTK9 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 29 kDa and the accession number is Q12792-4. | |||
TMPJ-01124 |
PDIA6 Protein, Human, Recombinant (His)
Thioredoxin Domain-Containing Protein 7,P5,ERP5,TXNDC7,Prote... |
Human | HEK293 Cells |
Protein Disulfide-Isomerase A6 (PDIA6) is a 48.5kDa protein that belongs to the protein disulfide isomerase family (PDI). PDIA6 is an enzyme in the endoplasmic reticulum in eukaryotes which catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. The PDIA6 expressed in platelets, its functions as a chaperone that inhibits aggregation of misfolded proteins. PDIA6 is part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA... | |||
TMPY-01339 |
S100A6 Protein, Human, Recombinant (His)
2A9,PRA,CABP,CACY,S100 calcium binding protein A6,5... |
Human | Baculovirus Insect Cells |
S100A6 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 12 kDa and the accession number is P06703. | |||
TMPY-05781 |
LILRA6 Protein, Human, Recombinant (His)
LILRB6,ILT-8,ILT5,LILRB3,ILT8,CD85b |
Human | HEK293 Cells |
LILRA6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.78 kDa and the accession number is Q6PI73-1. | |||
TMPK-01046 |
LILRA6 Protein, Human, Recombinant (His & Avi)
ILT8,7M1,Pira3,LILRA6,CD85b |
Human | HEK293 Cells |
The LILRs are a family of receptors that regulate the activities of myelomonocytic cells. Specific allelic variants of two related members of the LILR family, LILRB3 and LILRA6, interact with a ligand exposed on necrotic glandular epithelial cells. The extracellular domains of LILRB3 and LILRA6 are very similar and their genes are highly polymorphic. LILRA6 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 49.2 kD... | |||
TMPH-02324 |
SLC39A6 Protein, Human, Recombinant (His)
|
Human | Baculovirus Insect Cells |
May act as a zinc-influx transporter. SLC39A6 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 35.0 kDa and the accession number is Q13433. | |||
TMPH-02006 |
STRA6 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
STRA6 Protein, Human, Recombinant (hFc) is expressed in HEK293. | |||
TMPK-00519 |
LILRA6 Protein, Cynomolgus, Recombinant (His)
ILT8,LILRA6,Pira3,CD85b,7M1 |
Cynomolgus | HEK293 Cells |
The LILRs are a family of receptors that regulate the activities of myelomonocytic cells. Specific allelic variants of two related members of the LILR family, LILRB3 and LILRA6, interact with a ligand exposed on necrotic glandular epithelial cells. The extracellular domains of LILRB3 and LILRA6 are very similar and their genes are highly polymorphic. LILRA6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 48.28 kDa an... | |||
TMPK-01047 |
LILRA6 Protein, Human, Recombinant (His & Avi), Biotinylated
7M1,LILRA6,CD85b,ILT8,Pira3 |
Human | HEK293 Cells |
The LILRs are a family of receptors that regulate the activities of myelomonocytic cells. Specific allelic variants of two related members of the LILR family, LILRB3 and LILRA6, interact with a ligand exposed on necrotic glandular epithelial cells. The extracellular domains of LILRB3 and LILRA6 are very similar and their genes are highly polymorphic. LILRA6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular wei... | |||
TMPH-03400 |
SLC17A6 Protein, Rat, Recombinant (His)
|
Rat | P. pastoris (Yeast) |
Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Involved in the regulation of retinal hyaloid vessel regression during postnatal development. May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas. SLC17A6 Protein, Rat, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 11.1 kDa an... | |||
TMPY-06748 |
UBA6 Protein, Human, Recombinant (GST)
ubiquitin-like modifier activating enzyme 6,UBE1L2,MOP-4,E1-... |
Human | Baculovirus Insect Cells |
UBA6 (Ubiquitin Like Modifier Activating Enzyme 6) is a Protein Coding gene. The UBA6 gene, located on 4q13.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. Uba6 is a homolog of the ubiquitin-activating enzyme, Uba1, and activates two ubiquitin-like proteins (UBLs), ubiquitin and FAT10. UBA6 is an alternative enzyme for ubiquitin activation in vertebrates that plays a pivotal role in early mouse development. UBA6 is widely expressed in the lymph n... | |||
TMPJ-00780 |
IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His)
Interferon α-K,Interferon α-6,IFN α6,Interferon α-54,干扰素,Int... |
Human | HEK293 Cells |
Interferon α-6 (IFN-α6) is a secreted protein which belongs to the α/β interferon family. IFN-α6 is produced by macrophages, expressed at low level, only 1.0% of the average gene in this release. IFN-α6 contains interferon alpha, beta and delta domain. IFN-α has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. | |||
TMPH-00906 |
SLC25A6 Protein, Human, Recombinant (His & KSI)
|
Human | E. coli |
SLC25A6 Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 20.2 kDa and the accession number is P12236. | |||
TMPY-01843 |
SEMA6A Protein, Human, Recombinant (His)
HT018,VIA,sema domain, transmembrane domain (TM), and cytopl... |
Human | HEK293 Cells |
SEMA6A, the first identified class 6 semaphorin, is contributed to regulate vascular development and adult angiogenesis. SEMA6A could inhibit proliferation, migration, and invasion in different glioma cell lines. That SEMA6A may be a potential prognostic biomarker in the treatment of GBM. Among different semaphorins tested by reverse transcriptase-polymerase chain reaction in human immune cells, the expression of class 6 transmembrane semaphorin SEMA6A was restricted to dendritic cells (DCs). | |||
TMPH-01184 |
CYP2A6 Protein, Human, Recombinant (His & Myc)
CYP2A3,Coumarin 7-hydroxylase,1,4-cineole 2-exo-monooxygenas... |
Human | E. coli |
CYP2A6 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPY-06305 |
SARS-CoV-2 Spike S1 Protein (Q52 & A67V & 69-70 deletion & 144 deletion & E484K & D614G & Q677H, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (Q52 & A67V & 69-70 deletion & 144 deletion & E484K & D614G & Q677H, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.07 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06392 |
SARS-CoV-2 Spike S1+S2 Protein (Q52R & A67V & 69-70 deletion & Y144 deletion & E484K & D614G & Q677H & F888L, His)
|
SARS-CoV-2 | Baculovirus Insect Cells |
SARS-CoV-2 Spike S1+S2 Protein (Q52R & A67V & 69-70 deletion & Y144 deletion & E484K & D614G & Q677H & F888L, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 133.96 kDa and the accession number is A0A6G7K2L4. | |||
TMPH-01122 |
COL6A6 Protein, Human, Recombinant (His)
COL6A6,Collagen alpha-6(VI) chain |
Human | E. coli |
COL6A6 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPY-06075 |
LILRA6 Protein, Human, Recombinant (hFc)
ILT5,LILRB6,CD85b,ILT8,LILRB3,ILT-8 |
Human | HEK293 Cells |
LILRA6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.1 kDa and the accession number is Q6PI73-1. | |||
TMPY-06226 |
SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His)
solute carrier family 39 member 6 |
Cynomolgus | HEK293 Cells |
Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like protein zinc transporters (LZTs). It is involved in maintaining the intracellular homeostasis of zinc, an ion that is essential in the control of cellular growth and differentiation. SLC39A6 plays a critical role in maintaining zinc homeostasis, and was originally identified as a... | |||
TMPH-03635 |
GRA6 Protein, Toxoplasma gondii, Recombinant (GST)
|
TOV-Toxoplasma gondii | E. coli |
Major granular component involved in excreted-secreted antigen (ESA) immunity. May have a structural role in the membranous network of the parasitophorous vacuole (PV). GRA6 Protein, Toxoplasma gondii, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 38.6 kDa and the accession number is Q27003. |