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刺激性免疫检查点蛋白

刺激性免疫检查点蛋白

刺激性免疫检查点蛋白与抑制途径减弱免疫系统相反,共刺激分子可通过增强免疫反应来对抗恶性细胞。恶性细胞通常通过抑制共刺激途径来促进肿瘤的发生。OX40、GITR、ICOS、4-1BB、CD40 等刺激检查点分子在调节 T 细胞效应功能中发挥关键作用,激活共刺激通路可能提高检查点抑制效果,导致持久的抗肿瘤反应。

TargetMol Recombinant Protein
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Species
Canine (9)
Cynomolgus (37)
Cynomolyus (1)
Human (137)
Mouse (64)
Rabbit (2)
Rat (27)
Rhesus (21)
Rhesus macaque (5)
Expression System
Baculovirus-Insect Cells (2)
E. coli (3)
HEK293 (245)
Human Cells (35)
Tag
AVI (31)
Avi (1)
C-6His (12)
C-6His-Avi (2)
C-Avi-6His (2)
C-Fc (6)
C-Fc-6His (4)
C-Fc-Avi (1)
C-His (9)
C-His-Avi (19)
C-hFc (4)
C-hFc-Avi (2)
C-mFc (1)
Fc (1)
His (99)
N-10His (1)
N-6His (3)
N-6His-Avi (1)
N-6His-Flag (2)
N-8His (1)
N-His (4)
N-His-Avi (2)
N-His-Flag (2)
N-hFc (1)
N-monomeric hFc (1)
None (2)
Tag Free (5)
hFc (81)
mFc (12)
rFc (8)
Cat. No. Product Name / Synonyms Species Expression System
TMPJ-00422 OX40/TNFRSF4 Protein, Mouse, Recombinant (His)
OX40/TNFRSF4 Protein, Mouse, Recombinant (His)
Mouse Human Cells
OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis o...
TMPJ-00555 B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated
B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated
Human Human Cells
The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or C...
TMPJ-00556 B7-2 Protein, Human, Recombinant (His)
B7-2 Protein, Human, Recombinant (His)
Human Human Cells
The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or C...
TMPJ-00615 CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (hFc)
CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (hFc)
Rhesus macaque Human Cells
CD27 antigen, also known as CD27L receptor, T-cell activation antigen CD27, T14, S152, Tp55, TNFRSF7 and Tumor necrosis factor receptor for superfamily member 7,...
TMPJ-00616 CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (His)
CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (His)
Rhesus macaque Human Cells
CD27 antigen, also known as CD27L receptor, T-cell activation antigen CD27, T14, S152, Tp55, TNFRSF7 and Tumor necrosis factor receptor for superfamily member 7,...
TMPJ-00630 B7-1 Protein, Cynomolgus, Recombinant (hFc)
B7-1 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus Human Cells
Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-pr...
TMPJ-00632 B7-2 Protein, Cynomolgus, Recombinant (hFc)
B7-2 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus Human Cells
T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play impo...
TMPJ-00634 CD40 Protein, Cynomolgus, Recombinant (His)
CD40 Protein, Cynomolgus, Recombinant (His)
Cynomolgus Human Cells
CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cel...
TMPJ-00641 B7-2 Protein, Rhesus macaque, Recombinant (His)
B7-2 Protein, Rhesus macaque, Recombinant (His)
Rhesus macaque Human Cells
T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play impo...
TMPJ-00920 CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)
CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)
Mouse Human Cells
CD40 Ligand, also known as TNFSF5, CD154, is a type II transmembrane glycoprotein member of the TNF superfamily. Mature mouse CD40 Ligand consists of a 22 amino ...
TMPJ-00958 B7-1 Protein, Rabbit, Recombinant (His)
B7-1 Protein, Rabbit, Recombinant (His)
Rabbit Human Cells
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of ...
TMPJ-00959 B7-2 Protein, Rabbit, Recombinant (His)
B7-2 Protein, Rabbit, Recombinant (His)
Rabbit Human Cells
T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play impo...
TMPJ-01420 CD40 Protein, Cynomolgus, Recombinant (hFc)
CD40 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus Human Cells
CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cel...
TMPJ-01441 OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His)
OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His)
Cynomolgus Human Cells
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and...
TMPJ-01458 OX40/TNFRSF4 Protein, Cynomolgus, Recombinant (His)
OX40/TNFRSF4 Protein, Cynomolgus, Recombinant (His)
Cynomolgus Human Cells
OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis o...
TMPK-00063 OX40L/TNFSF4 Trimer Protein, Human, Recombinant (His & Flag)
OX40L/TNFSF4 Trimer Protein, Human, Recombinant (His & Flag)
Human HEK293
Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L),which belongs to the tumor necrosis factor fam...
TMPK-00078 CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled
Human HEK293
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a...
TMPK-00079 CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His)
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His)
Human HEK293
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a...
TMPK-00080 CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
Human HEK293
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a...
TMPK-00086 ICOS Protein, Human, Recombinant (aa 21-134, His)
ICOS Protein, Human, Recombinant (aa 21-134, His)
Human HEK293
Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of ...
OX40/TNFRSF4 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00422
Species: Mouse
Expression System: Human Cells
Tag: C-6His
B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated
Cat.No: TMPJ-00555
Species: Human
Expression System: Human Cells
Tag: C-Avi-6His
B7-2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00556
Species: Human
Expression System: Human Cells
Tag: C-6His
CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (hFc)
Cat.No: TMPJ-00615
Species: Rhesus macaque
Expression System: Human Cells
Tag: C-Fc
CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPJ-00616
Species: Rhesus macaque
Expression System: Human Cells
Tag: C-6His
B7-1 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-00630
Species: Cynomolgus
Expression System: Human Cells
Tag: C-Fc
B7-2 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-00632
Species: Cynomolgus
Expression System: Human Cells
Tag: C-Fc
CD40 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00634
Species: Cynomolgus
Expression System: Human Cells
Tag: C-6His
B7-2 Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPJ-00641
Species: Rhesus macaque
Expression System: Human Cells
Tag: C-6His
CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)
Cat.No: TMPJ-00920
Species: Mouse
Expression System: Human Cells
Tag: N-6His
B7-1 Protein, Rabbit, Recombinant (His)
Cat.No: TMPJ-00958
Species: Rabbit
Expression System: Human Cells
Tag: C-6His
B7-2 Protein, Rabbit, Recombinant (His)
Cat.No: TMPJ-00959
Species: Rabbit
Expression System: Human Cells
Tag: C-6His
CD40 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-01420
Species: Cynomolgus
Expression System: Human Cells
Tag: C-Fc
OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-01441
Species: Cynomolgus
Expression System: Human Cells
Tag: N-8His
OX40/TNFRSF4 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-01458
Species: Cynomolgus
Expression System: Human Cells
Tag: C-6His
OX40L/TNFSF4 Trimer Protein, Human, Recombinant (His & Flag)
Cat.No: TMPK-00063
Species: Human
Expression System: HEK293
Tag: N-His-Flag
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled
Cat.No: TMPK-00078
Species: Human
Expression System: HEK293
Tag: N-His
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His)
Cat.No: TMPK-00079
Species: Human
Expression System: HEK293
Tag: N-His
CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
Cat.No: TMPK-00080
Species: Human
Expression System: HEK293
Tag: N-His
ICOS Protein, Human, Recombinant (aa 21-134, His)
Cat.No: TMPK-00086
Species: Human
Expression System: HEK293
Tag: C-His
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TargetMol Loading
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