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刺激性免疫检查点蛋白

刺激性免疫检查点蛋白

刺激性免疫检查点蛋白与抑制途径减弱免疫系统相反,共刺激分子可通过增强免疫反应来对抗恶性细胞。恶性细胞通常通过抑制共刺激途径来促进肿瘤的发生。OX40、GITR、ICOS、4-1BB、CD40 等刺激检查点分子在调节 T 细胞效应功能中发挥关键作用,激活共刺激通路可能提高检查点抑制效果,导致持久的抗肿瘤反应。

TargetMol Recombinant Protein
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Species
Canine (9)
Cynomolgus (37)
Cynomolyus (1)
Human (137)
Mouse (64)
Rabbit (2)
Rat (27)
Rhesus (21)
Rhesus macaque (5)
Expression System
Baculovirus-Insect Cells (2)
E. coli (3)
HEK293 (245)
Human Cells (35)
Tag
AVI (31)
Avi (1)
C-6His (12)
C-6His-Avi (2)
C-Avi-6His (2)
C-Fc (6)
C-Fc-6His (4)
C-Fc-Avi (1)
C-His (9)
C-His-Avi (19)
C-hFc (4)
C-hFc-Avi (2)
C-mFc (1)
Fc (1)
His (99)
N-10His (1)
N-6His (3)
N-6His-Avi (1)
N-6His-Flag (2)
N-8His (1)
N-His (4)
N-His-Avi (2)
N-His-Flag (2)
N-hFc (1)
N-monomeric hFc (1)
None (2)
Tag Free (5)
hFc (81)
mFc (12)
rFc (8)
Cat. No. Product Name / Synonyms Species Expression System
TMPY-03914 B7-H3 Protein, Rat, Recombinant (hFc)
B7-H3 Protein, Rat, Recombinant (hFc)
Rat HEK293
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an impor...
TMPY-03944 CD40 Protein, Canine, Recombinant
CD40 Protein, Canine, Recombinant
Canine HEK293
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential r...
TMPY-04019 BTN3A3 Protein, Human, Recombinant (mFc)
BTN3A3 Protein, Human, Recombinant (mFc)
Human HEK293
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the...
TMPY-04065 CD40 Ligand Protein, Canine, Recombinant (mFc)
CD40 Ligand Protein, Canine, Recombinant (mFc)
Canine HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-04086 CD40 Ligand Protein, Canine, Recombinant
CD40 Ligand Protein, Canine, Recombinant
Canine HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-04089 CD40 Protein, Canine, Recombinant (His)
CD40 Protein, Canine, Recombinant (His)
Canine HEK293
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential r...
TMPY-04208 CD48 Protein, Mouse, Recombinant (hFc)
CD48 Protein, Mouse, Recombinant (hFc)
Mouse HEK293
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfami...
TMPY-04252 CD28 Protein, Rat, Recombinant (His)
CD28 Protein, Rat, Recombinant (His)
Rat HEK293
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single ...
TMPY-04279 B7-H3 Protein, Mouse, Recombinant (His), Biotinylated
B7-H3 Protein, Mouse, Recombinant (His), Biotinylated
Mouse HEK293
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an impor...
TMPY-04284 B7-H3 Protein, Rat, Recombinant (His)
B7-H3 Protein, Rat, Recombinant (His)
Rat HEK293
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an impor...
TMPY-04349 B7-1 Protein, Cynomolgus, Rhesus, Recombinant (His)
B7-1 Protein, Cynomolgus, Rhesus, Recombinant (His)
Cynomolgus,Rhesus HEK293
The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the ...
TMPY-04350 ICOS ligand Protein, Mouse, Recombinant (His)
ICOS ligand Protein, Mouse, Recombinant (His)
Mouse HEK293
Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmemb...
TMPY-04354 OX40L/TNFSF4 Protein, Human, Recombinant (mFc)
OX40L/TNFSF4 Protein, Human, Recombinant (mFc)
Human HEK293
OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecul...
TMPY-04495 B7-H6 Protein, Rat, Recombinant (His)
B7-H6 Protein, Rat, Recombinant (His)
Rat HEK293
B7-H6 Protein, Rat, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 35.1 kDa. Accession number: XP_006223356.1
TMPY-04497 CD70 Protein, Mouse, Recombinant (mFc)
CD70 Protein, Mouse, Recombinant (mFc)
Mouse HEK293
CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its recept...
TMPY-04585 B7-H3 Protein, Cynomolgus, Recombinant (His)
B7-H3 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an impor...
TMPY-04617 B7-H6 Protein, Cynomolgus, Recombinant (hFc)
B7-H6 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293
B7-H6 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 53.2 kDa. Accession number: XP_005578557.1
TMPY-04618 B7-H6 Protein, Cynomolgus, Recombinant (His)
B7-H6 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293
B7-H6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 27.9 kDa. Accession number: XP_005578557.1
TMPY-04619 B7-H6 Protein, Human, Recombinant (His)
B7-H6 Protein, Human, Recombinant (His)
Human HEK293
B7-H6 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 28.1 kDa. Accession number: Q68D85
TMPY-04718 OX40/TNFRSF4 Protein, Rhesus, Recombinant (hFc)
OX40/TNFRSF4 Protein, Rhesus, Recombinant (hFc)
Rhesus HEK293
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an ex...
B7-H3 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03914
Species: Rat
Expression System: HEK293
Tag: hFc
CD40 Protein, Canine, Recombinant
Cat.No: TMPY-03944
Species: Canine
Expression System: HEK293
Tag: Tag Free
BTN3A3 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-04019
Species: Human
Expression System: HEK293
Tag: mFc
CD40 Ligand Protein, Canine, Recombinant (mFc)
Cat.No: TMPY-04065
Species: Canine
Expression System: HEK293
Tag: mFc
CD40 Ligand Protein, Canine, Recombinant
Cat.No: TMPY-04086
Species: Canine
Expression System: HEK293
Tag: Tag Free
CD40 Protein, Canine, Recombinant (His)
Cat.No: TMPY-04089
Species: Canine
Expression System: HEK293
Tag: His
CD48 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-04208
Species: Mouse
Expression System: HEK293
Tag: hFc
CD28 Protein, Rat, Recombinant (His)
Cat.No: TMPY-04252
Species: Rat
Expression System: HEK293
Tag: His
B7-H3 Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-04279
Species: Mouse
Expression System: HEK293
Tag: His
B7-H3 Protein, Rat, Recombinant (His)
Cat.No: TMPY-04284
Species: Rat
Expression System: HEK293
Tag: His
B7-1 Protein, Cynomolgus, Rhesus, Recombinant (His)
Cat.No: TMPY-04349
Species: Cynomolgus,Rhesus
Expression System: HEK293
Tag: His
ICOS ligand Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04350
Species: Mouse
Expression System: HEK293
Tag: His
OX40L/TNFSF4 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-04354
Species: Human
Expression System: HEK293
Tag: mFc
B7-H6 Protein, Rat, Recombinant (His)
Cat.No: TMPY-04495
Species: Rat
Expression System: HEK293
Tag: His
CD70 Protein, Mouse, Recombinant (mFc)
Cat.No: TMPY-04497
Species: Mouse
Expression System: HEK293
Tag: mFc
B7-H3 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-04585
Species: Cynomolgus
Expression System: HEK293
Tag: His
B7-H6 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-04617
Species: Cynomolgus
Expression System: HEK293
Tag: hFc
B7-H6 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-04618
Species: Cynomolgus
Expression System: HEK293
Tag: His
B7-H6 Protein, Human, Recombinant (His)
Cat.No: TMPY-04619
Species: Human
Expression System: HEK293
Tag: His
OX40/TNFRSF4 Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-04718
Species: Rhesus
Expression System: HEK293
Tag: hFc
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TargetMol Loading
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