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刺激性免疫检查点蛋白

刺激性免疫检查点蛋白

刺激性免疫检查点蛋白与抑制途径减弱免疫系统相反,共刺激分子可通过增强免疫反应来对抗恶性细胞。恶性细胞通常通过抑制共刺激途径来促进肿瘤的发生。OX40、GITR、ICOS、4-1BB、CD40 等刺激检查点分子在调节 T 细胞效应功能中发挥关键作用,激活共刺激通路可能提高检查点抑制效果,导致持久的抗肿瘤反应。

TargetMol Recombinant Protein
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Species
Canine (9)
Cynomolgus (37)
Cynomolyus (1)
Human (137)
Mouse (64)
Rabbit (2)
Rat (27)
Rhesus (21)
Rhesus macaque (5)
Expression System
Baculovirus-Insect Cells (2)
E. coli (3)
HEK293 (245)
Human Cells (35)
Tag
AVI (31)
Avi (1)
C-6His (12)
C-6His-Avi (2)
C-Avi-6His (2)
C-Fc (6)
C-Fc-6His (4)
C-Fc-Avi (1)
C-His (9)
C-His-Avi (19)
C-hFc (4)
C-hFc-Avi (2)
C-mFc (1)
Fc (1)
His (99)
N-10His (1)
N-6His (3)
N-6His-Avi (1)
N-6His-Flag (2)
N-8His (1)
N-His (4)
N-His-Avi (2)
N-His-Flag (2)
N-hFc (1)
N-monomeric hFc (1)
None (2)
Tag Free (5)
hFc (81)
mFc (12)
rFc (8)
Cat. No. Product Name / Synonyms Species Expression System
TMPY-06209 ICOS Protein, Mouse, Recombinant (His)
ICOS Protein, Mouse, Recombinant (His)
Mouse HEK293
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 fa...
TMPY-06279 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His), Biotinylated
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His), Biotinylated
Mouse HEK293
CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necro...
TMPY-06280 2B4/CD244 Protein, Human, Recombinant (hFc & Avi), Biotinylated
2B4/CD244 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Human HEK293
The CD244 antigen, also known as 2B4, is a cell surface glycoprotein implicated in the regulation of natural killer and T lymphocyte function. 2B4 is a member of...
TMPY-06283 CD48 Protein, Human, Recombinant (His & Avi), Biotinylated
CD48 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfami...
TMPY-06294 2B4/CD244 Protein, Human, Recombinant (His & Avi), Biotinylated
2B4/CD244 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293
The CD244 antigen, also known as 2B4, is a cell surface glycoprotein implicated in the regulation of natural killer and T lymphocyte function. 2B4 is a member of...
TMPY-06298 B7-1 Protein, Human, Recombinant (His & Avi), Biotinylated
B7-1 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293
The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the ...
TMPY-06299 CD48 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD48 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Human HEK293
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfami...
TMPY-06329 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-211, His&AVI), Biotinylated
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-211, His&AVI), Biotinylated
Mouse HEK293
CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necro...
TMPY-06363 B7-H6 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
B7-H6 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
Cynomolgus HEK293
B7-H6 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 with His and AVI tag. The predicted molecular weight is 29.76 kDa. Access...
TMPY-06374 CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (mFc)
CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (mFc)
Human,Cynomolgus,Rhesus HEK293
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single ...
TMPY-06382 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His & Avi), Biotinylated
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293
CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necro...
TMPY-06528 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (soluble CD137, His)
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (soluble CD137, His)
Human HEK293
CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necro...
TMPY-06581 B7-H3 Protein, Human, Recombinant (isoform 2, His)
B7-H3 Protein, Human, Recombinant (isoform 2, His)
Human HEK293
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an impor...
TMPY-06622 CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (His & Avi), Biotinylated
CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (His & Avi), Biotinylated
Human,Cynomolgus,Rhesus HEK293
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single ...
TMPY-06687 CD40 Ligand Protein, Mouse, Recombinant (His)
CD40 Ligand Protein, Mouse, Recombinant (His)
Mouse HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-06711 B7-1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
B7-1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Mouse HEK293
The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the ...
TMPY-06770 CD70 Protein, Mouse, Recombinant (His & Avi), Biotinylated
CD70 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Mouse HEK293
CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its recept...
TMPY-06790 CD70 Protein, Mouse, Recombinant (His)
CD70 Protein, Mouse, Recombinant (His)
Mouse HEK293
CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its recept...
TMPY-06791 CD200 Protein, Human, Recombinant (His & Avi), Biotinylated
CD200 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expre...
TMPY-06794 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-187, His & Avi), Biotinylated
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-187, His & Avi), Biotinylated
Mouse HEK293
CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necro...
ICOS Protein, Mouse, Recombinant (His)
Cat.No: TMPY-06209
Species: Mouse
Expression System: HEK293
Tag: His
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-06279
Species: Mouse
Expression System: HEK293
Tag: His
2B4/CD244 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06280
Species: Human
Expression System: HEK293
Tag: hFc,AVI
CD48 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06283
Species: Human
Expression System: HEK293
Tag: His, Avi
2B4/CD244 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06294
Species: Human
Expression System: HEK293
Tag: His,AVI
B7-1 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06298
Species: Human
Expression System: HEK293
Tag: His,AVI
CD48 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06299
Species: Human
Expression System: HEK293
Tag: hFc,AVI
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-211, His&AVI), Biotinylated
Cat.No: TMPY-06329
Species: Mouse
Expression System: HEK293
Tag: His,AVI
B7-H6 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06363
Species: Cynomolgus
Expression System: HEK293
Tag: His,AVI
CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (mFc)
Cat.No: TMPY-06374
Species: Human,Cynomolgus,Rhesus
Expression System: HEK293
Tag: mFc
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06382
Species: Human
Expression System: HEK293
Tag: His,AVI
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (soluble CD137, His)
Cat.No: TMPY-06528
Species: Human
Expression System: HEK293
Tag: His
B7-H3 Protein, Human, Recombinant (isoform 2, His)
Cat.No: TMPY-06581
Species: Human
Expression System: HEK293
Tag: His
CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06622
Species: Human,Cynomolgus,Rhesus
Expression System: HEK293
Tag: His,AVI
CD40 Ligand Protein, Mouse, Recombinant (His)
Cat.No: TMPY-06687
Species: Mouse
Expression System: HEK293
Tag: His
B7-1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06711
Species: Mouse
Expression System: HEK293
Tag: His,AVI
CD70 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06770
Species: Mouse
Expression System: HEK293
Tag: His,AVI
CD70 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-06790
Species: Mouse
Expression System: HEK293
Tag: His
CD200 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06791
Species: Human
Expression System: HEK293
Tag: His,AVI
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-187, His & Avi), Biotinylated
Cat.No: TMPY-06794
Species: Mouse
Expression System: HEK293
Tag: His,AVI
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TargetMol Loading
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