刺激性免疫检查点蛋白

刺激性免疫检查点蛋白与抑制途径减弱免疫系统相反，共刺激分子可通过增强免疫反应来对抗恶性细胞。恶性细胞通常通过抑制共刺激途径来促进肿瘤的发生。OX40、GITR、ICOS、4-1BB、CD40 等刺激检查点分子在调节 T 细胞效应功能中发挥关键作用，激活共刺激通路可能提高检查点抑制效果，导致持久的抗肿瘤反应。

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Cat. No.	Product Name / Synonyms	Species	Expression System
TMPY-06813	ICOS ligand Protein, Human, Recombinant ICOS ligand Protein, Human, Recombinant	Human	HEK293
TMPY-06813	Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmemb...
TMPY-06831	4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (hFc) 4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
TMPY-06831	4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfam...
TMPY-06875	OX40/TNFRSF4 Protein, Human, Recombinant (hFc & Avi), Biotinylated OX40/TNFRSF4 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
TMPY-06875	OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an ex...
TMPY-06880	CD86 Protein, Human, Recombinant (His & Avi), Biotinylated CD86 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPY-06880	CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominan...
TMPY-06906	OX40/TNFRSF4 Protein, Human, Recombinant (His & Avi), Biotinylated OX40/TNFRSF4 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPY-06906	OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an ex...
TMPY-06909	B7-1 Protein, Rat, Recombinant (His) B7-1 Protein, Rat, Recombinant (His)	Rat	HEK293
TMPY-06909	The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the ...
TMPY-06953	CD70 Protein, Human, Recombinant (His) CD70 Protein, Human, Recombinant (His)	Human	HEK293
TMPY-06953	CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its recept...
TMPY-06979	ICOS Protein, Human, Recombinant (His) ICOS Protein, Human, Recombinant (His)	Human	HEK293
TMPY-06979	Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 fa...
TMPY-01672	ICOS ligand Protein, Human, Recombinant (His) ICOS ligand Protein, Human, Recombinant (His)	Human	HEK293
TMPY-01672	Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmemb...
TMPY-00699	CD155/PVR Protein, Human, Recombinant (hFc) CD155/PVR Protein, Human, Recombinant (hFc)	Human	HEK293
TMPY-00699	CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the ne...
TMPY-01386	CD155/PVR Protein, Human, Recombinant (His) CD155/PVR Protein, Human, Recombinant (His)	Human	HEK293
TMPY-01386	CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the ne...
TMPY-01152	DNAM-1/CD226 Protein, Human, Recombinant (His) DNAM-1/CD226 Protein, Human, Recombinant (His)	Human	HEK293
TMPY-01152	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-05354	CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
TMPY-05354	CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single ...
TMPY-01181	CD40 Protein, Human, Recombinant (His) CD40 Protein, Human, Recombinant (His)	Human	HEK293
TMPY-01181	CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential r...
TMPY-05376	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc) 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc)	Human	HEK293
TMPY-05376	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necro...
TMPY-03401	CD27/TNFRSF7 Protein, Human, Recombinant (His) CD27/TNFRSF7 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
TMPY-03401	CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on t...
TMPY-06021	CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (His) CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (His)	Human,Cynomolgus,Rhesus	HEK293
TMPY-06021	CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single ...
TMPY-01423	OX40/TNFRSF4 Protein, Human, Recombinant (His) OX40/TNFRSF4 Protein, Human, Recombinant (His)	Human	HEK293
TMPY-01423	OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an ex...
TMPY-01743	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His) 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His)	Human	HEK293
TMPY-01743	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necro...
TMPY-02022	CD40 Ligand Protein, Human, Recombinant (hFc) CD40 Ligand Protein, Human, Recombinant (hFc)	Human	HEK293
TMPY-02022	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified...