刺激性免疫检查点蛋白与抑制途径减弱免疫系统相反,共刺激分子可通过增强免疫反应来对抗恶性细胞。恶性细胞通常通过抑制共刺激途径来促进肿瘤的发生。OX40、GITR、ICOS、4-1BB、CD40 等刺激检查点分子在调节 T 细胞效应功能中发挥关键作用,激活共刺激通路可能提高检查点抑制效果,导致持久的抗肿瘤反应。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-03089 | CD48 Protein, Rat, Recombinant (His)
CD48 Protein, Rat, Recombinant (His)
|
Rat | HEK293 |
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfami... | |||
TMPY-03129 | CD70 Protein, Rat, Recombinant (hFc)
CD70 Protein, Rat, Recombinant (hFc)
|
Rat | HEK293 |
CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its recept... | |||
TMPY-03159 | CD70 Protein, Rat, Recombinant (His)
CD70 Protein, Rat, Recombinant (His)
|
Rat | HEK293 |
CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its recept... | |||
TMPY-03207 | CD48 Protein, Rat, Recombinant (hFc)
CD48 Protein, Rat, Recombinant (hFc)
|
Rat | HEK293 |
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfami... | |||
TMPY-03211 | CD40 Protein, Rhesus, Recombinant (hFc)
CD40 Protein, Rhesus, Recombinant (hFc)
|
Rhesus | HEK293 |
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential r... | |||
TMPY-03212 | CD40 Protein, Rhesus, Recombinant (His)
CD40 Protein, Rhesus, Recombinant (His)
|
Rhesus | HEK293 |
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential r... | |||
TMPY-03301 | CD40 Ligand Protein, Rat, Recombinant (hFc)
CD40 Ligand Protein, Rat, Recombinant (hFc)
|
Rat | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified... | |||
TMPY-03311 | ICOS Protein, Rat, Recombinant (hFc)
ICOS Protein, Rat, Recombinant (hFc)
|
Rat | HEK293 |
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 fa... | |||
TMPY-03348 | CD226 Protein, Rat, Recombinant (hFc)
CD226 Protein, Rat, Recombinant (hFc)
|
Rat | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified... | |||
TMPY-03373 | CD27/TNFRSF7 Protein, Rhesus, Recombinant (hFc)
CD27/TNFRSF7 Protein, Rhesus, Recombinant (hFc)
|
Rhesus | HEK293 |
CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on t... | |||
TMPY-03380 | CD200 Protein, Rhesus, Recombinant (hFc)
CD200 Protein, Rhesus, Recombinant (hFc)
|
Rhesus | HEK293 |
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expre... | |||
TMPY-03525 | ICOS ligand Protein, Human, Recombinant (hFc)
ICOS ligand Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmemb... | |||
TMPY-03542 | CD40 Ligand Protein, Rhesus, Recombinant (hFc)
CD40 Ligand Protein, Rhesus, Recombinant (hFc)
|
Rhesus | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified... | |||
TMPY-03562 | CD86 Protein, Cynomolgus, Rhesus, Recombinant (hFc)
CD86 Protein, Cynomolgus, Rhesus, Recombinant (hFc)
|
Cynomolgus,Rhesus | HEK293 |
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominan... | |||
TMPY-03595 | CD200 Protein, Rhesus, Recombinant (His)
CD200 Protein, Rhesus, Recombinant (His)
|
Rhesus | HEK293 |
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expre... | |||
TMPY-03646 | CD86 Protein, Cynomolgus, Rhesus, Recombinant (His)
CD86 Protein, Cynomolgus, Rhesus, Recombinant (His)
|
Cynomolgus,Rhesus | HEK293 |
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominan... | |||
TMPY-03741 | B7-1 Protein, Cynomolgus, Rhesus, Recombinant (hFc)
B7-1 Protein, Cynomolgus, Rhesus, Recombinant (hFc)
|
Cynomolgus,Rhesus | HEK293 |
The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the ... | |||
TMPY-03773 | 4-1BB/CD137/TNFRSF9 Protein, Canine, Recombinant (His)
4-1BB/CD137/TNFRSF9 Protein, Canine, Recombinant (His)
|
Canine | HEK293 |
CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necro... | |||
TMPY-03875 | OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (mFc)
OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (mFc)
|
Cynomolgus | HEK293 |
OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecul... | |||
TMPY-03907 | CD40 Protein, Canine, Recombinant (hFc)
CD40 Protein, Canine, Recombinant (hFc)
|
Canine | HEK293 |
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential r... |