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刺激性免疫检查点蛋白

刺激性免疫检查点蛋白

刺激性免疫检查点蛋白与抑制途径减弱免疫系统相反,共刺激分子可通过增强免疫反应来对抗恶性细胞。恶性细胞通常通过抑制共刺激途径来促进肿瘤的发生。OX40、GITR、ICOS、4-1BB、CD40 等刺激检查点分子在调节 T 细胞效应功能中发挥关键作用,激活共刺激通路可能提高检查点抑制效果,导致持久的抗肿瘤反应。

TargetMol Recombinant Protein
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Species
Canine (9)
Cynomolgus (37)
Cynomolyus (1)
Human (137)
Mouse (64)
Rabbit (2)
Rat (27)
Rhesus (21)
Rhesus macaque (5)
Expression System
Baculovirus-Insect Cells (2)
E. coli (3)
HEK293 (245)
Human Cells (35)
Tag
AVI (31)
Avi (1)
C-6His (12)
C-6His-Avi (2)
C-Avi-6His (2)
C-Fc (6)
C-Fc-6His (4)
C-Fc-Avi (1)
C-His (9)
C-His-Avi (19)
C-hFc (4)
C-hFc-Avi (2)
C-mFc (1)
Fc (1)
His (99)
N-10His (1)
N-6His (3)
N-6His-Avi (1)
N-6His-Flag (2)
N-8His (1)
N-His (4)
N-His-Avi (2)
N-His-Flag (2)
N-hFc (1)
N-monomeric hFc (1)
None (2)
Tag Free (5)
hFc (81)
mFc (12)
rFc (8)
Cat. No. Product Name / Synonyms Species Expression System
TMPY-03967 BTN3A3 Protein, Human, Recombinant (His)
BTN3A3 Protein, Human, Recombinant (His)
Human HEK293
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the...
TMPY-04951 CD27/TNFRSF7 Protein, Human, Recombinant (His), Biotinylated
CD27/TNFRSF7 Protein, Human, Recombinant (His), Biotinylated
Human Baculovirus-Insect Cells
CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on t...
TMPY-05156 ICOS Protein, Human, Recombinant (rFc)
ICOS Protein, Human, Recombinant (rFc)
Human HEK293
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 fa...
TMPY-05504 4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated
4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated
Rhesus HEK293
CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necro...
TMPY-05641 B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an impor...
BTN3A3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03967
Species: Human
Expression System: HEK293
Tag: His
CD27/TNFRSF7 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04951
Species: Human
Expression System: Baculovirus-Insect Cells
Tag: His
ICOS Protein, Human, Recombinant (rFc)
Cat.No: TMPY-05156
Species: Human
Expression System: HEK293
Tag: rFc
4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated
Cat.No: TMPY-05504
Species: Rhesus
Expression System: HEK293
Tag: His
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05641
Species: Human
Expression System: HEK293
Tag: His,AVI
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TargetMol Loading
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