CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (His & Avi), Biotinylated

CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 18.40 kDa and the accession number is P10747-1.

规格	价格/CNY		货期	数量
20 μg	￥ 2,530	5日内发货
100 μg	￥ 6,390	5日内发货

规格

价格/CNY

货期

数量

20 μg

￥ 2,530

5日内发货

100 μg

￥ 6,390

5日内发货

生物活性	Immobilized Recombinant Mouse CD80 / B7-1 Protein (Fc Tag) at 2 μg/ml (100 μl/well) can bind Recombinant Human/Cynomolgus/Rhesus CD28 Protein(ECD,His&AVI Tag),Biotinylated, The EC50 is 800-2100 ng/mL.
产品描述	CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 18.40 kDa and the accession number is P10747-1.

种属	Human,Cynomolgus,Rhesus
表达系统	HEK293 Cells
标签	C-His-Avi
蛋白编号	P10747-1
别名	CD28 molecule
蛋白构建	The Human/Cynomolgus/Rhesus CD28 (P10747-1) (Met1-Pro152) was expressed with a C-terminal polyhistidine tag followed by an AVI tag. The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
蛋白纯度	> 95 % as determined by SDS-PAGE. > 95 % as determined by SEC-HPLC.
分子量	18.40 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy