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Search Results for " sympathomimetic "

30

抑制剂 & 化合物

6

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T8580	Bupranolol	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Bupranolol 是竞争性的、口服活性的、非选择性的β-adrenoceptor 拮抗剂，无固有的拟交感神经活性。
T0166	Pancuronium dibromide Pancuronium bromide,Pavulon,泮库溴铵	AChR	Neuroscience
	Pancuronium dibromide (Pavulon) 是一种双季基类固醇，是一种神经肌肉松弛剂。它通过与乙酰胆碱竞争 nACh 受体上的结合位点来抑制神经肌肉传递。它还可抑制心脏毒蕈碱受体并具有拟交感神经作用。
T10631L	Bucindolol Formate Bucindolol Formate (71119-11-4 Free base)	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Bucindolol Formate 是一种具有内源性拟交感活性的β1 肾上腺素能受体 (β1-adrenergic receptor) 阻滞剂。Bucindolol 可用于心力衰竭疾病研究。
T21445	Naphazoline AK-Con,Naphcon-a,Clear Eyes,All Clear,萘甲唑林	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Naphazoline (Naphcon-a) 是一种具有显着 α 肾上腺素能活性的拟交感神经化合物。萘甲唑啉可用作血管收缩剂，当应用于粘膜时可快速减少肿胀。
T16431	Pamatolol	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Pamatolol 是一种具有选择性和有效性的 beta-adrenoceptor 拮抗剂，在体内外实验中尚未显示出拟交感活性。
T10364	Arbutamine GP 21213	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Arbutamine (GP 21213) 是一种新型非选择性β-肾上腺素受体激动剂，具有α-1-拟交感神经活性。Arbutamine 促进心脏应激，增加心率、心脏收缩力。Arbutamine 可用于研究心脏应激和冠状动脉疾病。
T0342	Carvedilol phosphate hemihydrate Carvedilol phosphate,BM 14190 (phosphate hemihydrate),卡维地洛磷酸盐	VEGFR; Others; Potassium Channel; LDL; Integrin; Gap Junction Protein; NADPH; Adrenergic Receptor; Autophagy	Angiogenesis; Autophagy; Cytoskeletal Signaling; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience; Others; Tyrosine Kinase/Adaptors
	Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) 是一种外消旋混合物，是一种非选择性β/α-1受体阻断剂，具有抗高血压活性且缺乏内在拟交感神经活性。
T0279	Metaraminol tartrate 重酒石酸间羟胺,Metaradrine tartrate,Metaraminol bitartrate	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Metaraminol tartrate (Metaradrine tartrate) 是一种 α-肾上腺素能 (α-adrenergic) 激动剂，是一种直接或间接影响肾上腺素受体的拟交感神经胺，其中 α 效应占主导地位，可作为血管加压剂。
T1282	Carteolol hydrochloride Arteoptic,Abbott-43326,OPC-1085 hydrochloride,盐酸卡替洛尔,Carteolol HCl,Mikelan	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Carteolol hydrochloride (Abbott-43326) 是一种非选择性的β肾上腺素受体阻断剂。
T1012	Acebutolol hydrochloride 盐酸醋丁洛尔,Acebutolol HCl	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Acebutolol hydrochloride (Acebutolol HCl) 是一种 β-肾上腺素受体拮抗剂，用于研究高血压、心绞痛和心律失常。
T1577	Midodrine hydrochloride Pro-Amatine,盐酸米多君	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Midodrine hydrochloride (Pro-Amatine) 通过去甘氨酸反应转化为其活性代谢物 desglymidodrine。Desglymidodrine 选择性地结合并激活小动脉和静脉血管系统的 α-1-肾上腺素能受体。这会导致平滑肌收缩并导致血压升高。 Desglymidodrine 在血脑屏障中的扩散很差，因此与对中枢神经系统的影响无关。Midodrine hydrochloride 是 midodrine 的盐酸盐形式，是一种直接作用的前药和拟交感神经药，具有抗低血压特性。
T1139	Salbutamol Albuterol,沙丁胺醇,AH-3365	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Salbutamol (Albuterol) 是短效的 β2 肾上腺素受体激动剂，用于哮喘和慢性阻塞性肺疾病(COPD) 引发的支气管痉挛的研究。
T0871	Noradrenaline bitartrate	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Noradrenaline bitartrate 直接作用于 α 和 β 肾上腺素能受体。它是去甲肾上腺素的酒石酸氢盐，去甲肾上腺素是一种合成苯乙胺，可模拟内源性去甲肾上腺素的拟交感神经作用。临床上，去甲肾上腺素用作外周血管收缩剂，通过其α-肾上腺素能作用导致动脉和静脉床收缩。它还被用作通过其 β-1 肾上腺素能作用介导的强效正性肌力和变时性心脏刺激剂。
T0279L	Metaraminol Icoral B,Pressonex,CCRIS 8465,l-Metaraminol
	Metaraminol is a sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors.
T70216	Clonazoline
	Clonazoline is a coronary vasodilator that is an imidazoline sympathomimetic, an alpha-adrenoreceptor agonist. It was used as a nasal decongestant and vasoconstrictor.
T69270	Amezinium
	Amezinium is a sympathomimetic drug used for the treatment of low blood pressure. It has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition of noradrenaline and tyramine uptake.
T26762	Befunolol HCl BFE60,Bentox,Befunolol hydrochloride,BFE-60,BFE 60
	Befunolol is a beta blocker with intrinsic sympathomimetic activity and also acts as a β adrenoreceptor partial agonist.
T16043	Metaproterenol Orciprenaline	BCL	Apoptosis
	Metaproterenol also has anti-inflammatory activity. Metaproterenol is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist (IC50: 68 nM).
T33287	Mephentermine Sulfate sulfuric acid,MLS002153976,N,2-dimethyl-1-phenylpropan-2-amine,AC1NWAW7,Mephentermine sodium
	Mephentermine sulfate is a cardiac stimulant, before as a stimulant in psychiatry, has been used as a treatment for low blood pressure. Mephentermine sulfate is a sympathomimetic agent with specificity for alpha-1 adrenergic receptors. It is used to maint
T21411L	Isoproterenol bitartrate
	Isoproterenol bitartrate is a beta-sympathomimetic and an isopropyl analog of Epinephrine, which acts on the heart, bronchi, skeletal muscle, and alimentary tract. It is used mainly as a bronchodilator and heart stimulant.
T69670	Clonazoline HCl
	Clonazoline HCl is the salt form of Clonazoline, a coronary vasodilator that is an imidazoline sympathomimetic, an alpha-adrenoreceptor agonist. It was used as a nasal decongestant and vasoconstrictor.
T0279L2	Metaraminol hydrochloride Metaraminol HCl
	Metaraminol hydrochloride, used primarily as a vasoconstrictor in the treatment of HYPOTENSION, is a sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors.
T82564	Dibutepinephrine
	Dibutepinephrine是一种仿生拟交感神经药物，具有选择性地激活α和β肾上腺素能受体的作用。
T69697	Dioxethedrin HCl
	Dioxethedrin HCl is the ephedrine derivative. It is the beta-adrenergic agonist. As a bronchodilator and sympathomimetic agent is was used in antitussive syrup Bexol.
T73216	Gepefrine
	Gepefrine为具口服活性的升压剂及拟交感神经作用剂，能有效改善动脉压早期直立性失调。
T5450	DL-071-IT Afurolol Hydrochloride,DL 071 IT	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	DL-071-IT (Afurolol Hydrochloride) 是一种有效的非选择性β-肾上腺素受体拮抗剂。 DL-071-IT 表现出内在的拟交感神经活性和弱的膜稳定活性。
T69107	Doxaminol
	Doxaminol is a synthetic partial beta-adrenergic agonist with sympathomimetic activity. Doxaminol may bind to and stimulate beta-1-adrenergic receptors located in the myocardium. As a result, it leads to a positive inotropic effect and increases in cardiac output.
T64309	Isometheptene mucate
	Isometheptene mucate 是一种拟交感神经剂，是间接作用的肾上腺素能受体 (adrenergic receptor) 激动剂，能够用于研究偏头痛。
T70506	Bupranolol HCl
	Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane stabilizing activity. Its potency is similar to propranolol. Bupranolol is quickly and completely absorbed from the gut. Over 90% undergo first-pass metabolism. Bupranolol has a plasma half life of about two to four hours, with levels never reaching 1 µg/l in therapeutic doses. The main metabolite is carboxybupranolol, 4-chloro-3-[3-(1,1-dimethylethylamino)-2-hydroxy-propyloxy]be...
T69127	Moxisylyte
	Moxisylyte, also known as thymoxamine, is a drug used in urology for the treatment of erectile dysfunction. It is an α1-adrenergic antagonist. Moxisylyte is also used for the short-term treatment of primary Reynaud's syndrome, a condition where the fingers and toes become discoloured in response to cold or emotional distress. Moxisylyte helps by improving blood circulation to the extremities. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomi...

化合物

Cat.No: T8580

Target: Adrenergic Receptor

Pancuronium dibromide

Cat.No: T0166

Synonym: Pancuronium bromide,Pavulon,泮库溴铵

Target: AChR

Bucindolol Formate

Cat.No: T10631L

Synonym: Bucindolol Formate (71119-11-4 Free base)

Target: Adrenergic Receptor

Cat.No: T21445

Synonym: AK-Con,Naphcon-a,Clear Eyes,All Clear,萘甲唑林

Target: Adrenergic Receptor

Cat.No: T16431

Target: Adrenergic Receptor

Cat.No: T10364

Synonym: GP 21213

Target: Adrenergic Receptor

Carvedilol phosphate hemihydrate

Cat.No: T0342

Synonym: Carvedilol phosphate,BM 14190 (phosphate hemihydrate),卡维地洛磷酸盐

Target: VEGFR, Others, Potassium Channel, LDL, Integrin, Gap Junction Protein, NADPH, Adrenergic Receptor, Autophagy

Metaraminol tartrate

Cat.No: T0279

Synonym: 重酒石酸间羟胺,Metaradrine tartrate,Metaraminol bitartrate

Target: Adrenergic Receptor

Carteolol hydrochloride

Cat.No: T1282

Synonym: Arteoptic,Abbott-43326,OPC-1085 hydrochloride,盐酸卡替洛尔,Carteolol HCl,Mikelan

Target: Adrenergic Receptor

Acebutolol hydrochloride

Cat.No: T1012

Synonym: 盐酸醋丁洛尔,Acebutolol HCl

Target: Adrenergic Receptor

Midodrine hydrochloride

Cat.No: T1577

Synonym: Pro-Amatine,盐酸米多君

Target: Adrenergic Receptor

Cat.No: T1139

Synonym: Albuterol,沙丁胺醇,AH-3365

Target: Adrenergic Receptor

Noradrenaline bitartrate

Cat.No: T0871

Target: Adrenergic Receptor

Cat.No: T0279L

Synonym: Icoral B,Pressonex,CCRIS 8465,l-Metaraminol

Cat.No: T70216

Cat.No: T69270

Cat.No: T26762

Synonym: BFE60,Bentox,Befunolol hydrochloride,BFE-60,BFE 60

Cat.No: T16043

Synonym: Orciprenaline

Target: BCL

Mephentermine Sulfate

Cat.No: T33287

Synonym: sulfuric acid,MLS002153976,N,2-dimethyl-1-phenylpropan-2-amine,AC1NWAW7,Mephentermine sodium

Isoproterenol bitartrate

Cat.No: T21411L

Clonazoline HCl

Cat.No: T69670

Metaraminol hydrochloride

Cat.No: T0279L2

Synonym: Metaraminol HCl

Dibutepinephrine

Cat.No: T82564

Dioxethedrin HCl

Cat.No: T69697

Cat.No: T73216

Cat.No: T5450

Synonym: Afurolol Hydrochloride,DL 071 IT

Target: Adrenergic Receptor

Cat.No: T69107

Isometheptene mucate

Cat.No: T64309

Cat.No: T70506

Cat.No: T69127

Cat. No.	Product Name	Target	Signaling Pathways
T1287	Synephrine 辛弗林,Oxedrine	Endogenous Metabolite; Adrenergic Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Synephrine (Oxedrine) 是来自 Citrus aurantium 的α-adrenergic 和β-adrenergic 激动剂，是一种生物碱。它也是一种拟交感神经化合物，能够用于减肥。
T8149	Dobutamine hydrochloride 盐酸多巴酚丁胺,Dobutamine (hydrochloride)	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Dobutamine hydrochloride (Dobutamine(hydrochloride)) 是一种合成的儿茶酚胺，可作用于肾上腺素能受体α1-AR、β1-AR 和β2-AR，是一种选择性的 β1-AR 受体激动剂，对 α1-AR 和 β2-AR 作用相对较弱。它能够增加心输出量，矫正低灌注。
T6688	Synephrine hydrochloride 辛弗林盐酸盐,Oxedrine hydrochloride,Synephrine HCl	Endogenous Metabolite; Adrenergic Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Synephrine hydrochloride (Oxedrine hydrochloride) 是一种来自Citrus aurantium 的α-adrenergic 和β-adrenergic 激动剂的生物碱，也是一种拟交感神经化合物，能够用于减肥。
T1071L	DL-Adrenaline Hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	DL-Adrenaline Hydrochloride 是天然存在的拟交感神经胺的盐酸盐，具有收缩血管、降低眼内压的活性。
T3095	Tyramine 4-hydroxyphenethylamine,酪胺,para-tyramine,p-Tyramine,mydrial,Tocosine,Uteramine	MAO; Endogenous Metabolite	Metabolism; Neuroscience
	Tyramine (Uteramine) 是天然存在于体内或某些食物中的氨基酸。Tyramine 有助于调节血压。
T75425	Synephrine hemitartrate
	Synephrine (Oxedrine) hemitartrate，一种生物碱，是一种来自Citrus aurantium 的α-adrenergic 和β-adrenergic 激动剂。Synephrine hemitartrate 是一种拟交感神经化合物，可用于减肥。

天然产物

Cat.No: T1287

Synonym: 辛弗林,Oxedrine

Target: Endogenous Metabolite, Adrenergic Receptor

Dobutamine hydrochloride

Cat.No: T8149

Synonym: 盐酸多巴酚丁胺,Dobutamine (hydrochloride)

Target: Adrenergic Receptor

Synephrine hydrochloride

Cat.No: T6688

Synonym: 辛弗林盐酸盐,Oxedrine hydrochloride,Synephrine HCl

Target: Endogenous Metabolite, Adrenergic Receptor

DL-Adrenaline Hydrochloride

Cat.No: T1071L

Target: Adrenergic Receptor

Cat.No: T3095

Synonym: 4-hydroxyphenethylamine,酪胺,para-tyramine,p-Tyramine,mydrial,Tocosine,Uteramine

Target: MAO, Endogenous Metabolite

Synephrine hemitartrate

Cat.No: T75425

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