45
29
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T20045 |
C.I. Pigment Red 172
C.I. Acid Red 51:1,Pigment Red 172,Erythrosine-aluminum lake,C.I. Food Red 14:1,Tetraiodofluorescein,Aluminum,Acid Red 51:1 |
||
C.I. Pigment Red 172 (C.I. Food Red 14:1) 是一种食品添加剂。 | |||
T34064 |
Pigment Blue 15
AI3-26192,EINECS 205-685-1,Blue GLA,Blue pigment,Phthalocyanine Blue BN |
||
Pigment Blue 15, also called by many names (EINECS 205-685-1), is a bright, crystalline, synthetic blue pigment from the group of phthalocyanine dyes. Its brilliant blue is frequently used in paints and dyes. It is highly valued for its superior propertie | |||
T40742 |
Pigment Red 22
|
||
Pigment Red 22, a coloring agent, is a versatile compound employed in the formulation of various cosmetic products, including cleansing products, makeup, moisturizers, and night skin care products. | |||
T40609 |
Pigment Red 48:4
|
||
Pigment Red 48:4 is a manganese-complex dye suitable for applications in printing ink and paint systems. | |||
T30671 |
C.I. Pigment Yellow 14
|
||
C.I. Pigment Yellow 14 is a yellow dye. | |||
T20987 | C.I. Pigment Yellow 74 | ||
C.I. Pigment Yellow 74 is a bioactive chemical. | |||
T34065 |
Pigment Red 57
Lithol Rubine Na,Japan Red 201,Rubine Red RR 1253,Lithol rubin B |
||
Pigment Red 57, also known as D & C Red No. 6, is a synthetic dye produced from petroleum or coal tar sources; this dye is FDA-approved for use in pharmaceuticals and cosmetics. | |||
T30670 |
C.I. Pigment Red 4
CCRIS 4907,HSDB 7720,Oralith Red,C.I. 12085 |
||
C.I. Pigment Red 4可用于印刷油墨、油漆、水彩、油漆及砚色、橡胶、天然生漆、化妆品、油漆及涂料的印刷颜色。它是黄红色粉末,颜色鲜艳。不溶于水,微溶于乙醇和苯。它在浓硝酸中呈现鲜红色,在稀氢氧化钠溶液中保持鲜红色;在乙醇-氢氧化钾溶液中呈紫色。具有良好的流动性和抗遮盖性,耐热性差。 | |||
T20059 |
C.I. Pigment Red 60
NSC 12455,Acid Anthracene Red G,Siloton Red 3B,NSC12455,NSC-12455,Hispacrom Red B |
||
C.I. Pigment Red 60 is a bright, scarlet, semi-transparent red pigment. | |||
T30666 |
C.I. Food Blue 1-aluminum lake
EINECS 240-589-3,Indigotine-aluminum lake,Acid Blue 74-aluminum lake,Pigment Blue 63 |
||
C.I. Food Blue 1-aluminum lake is a type of colorant. | |||
T20043 |
D&C Red no. 31
D &,C Red no. 31,11067 Red,Brilliant Scarlet G,CCRIS 4906,Pigment Scarlet Toner RB |
||
D & C Red no. 31 is an agent of dye. | |||
T2055 |
WS3
|
EGFR; IκB/IKK | Angiogenesis; JAK/STAT signaling; NF-κB; Tyrosine Kinase/Adaptors |
WS3 是一种可促进鼠和人原代胰岛的胰腺 β 细胞增殖的增殖分子。它可用于研究 I 型糖尿病。 | |||
T20018 |
Barium lithol red
HSDB 5523,立索尔大红,PR-258,Barium lithol,1883 red |
Others | Others |
Barium lithol red (HSDB 5523) 是一种透明的蓝色调红色颜料,主要应用于印墨着色。 | |||
TP1120L |
IRBP acetate(211426-18-5 free base)
Interphotoreceptor Retinoid Binding Protein Fragment IRBP |
Others | Others |
IRBP acetate(211426-18-5 free base) (Interphotoreceptor Retinoid Binding Protein Fragment IRBP) 是一种含有 20 个残基的肽,是一种主要的致病表位。它存在于间质视觉色素结合蛋白肽(IRBP 161-180)的第一个同源重复序列中,可诱导葡萄膜炎后(EAU)。 | |||
T34444 | Rubroskyrin | ||
Rubroskyrin is a modified bis-anthraquinone pigment that comes from Penicillium islandicum Sopp. | |||
T32852 |
Lomatiol
NSC-24872,NSC24872,NSC 24872 |
||
Lomatiol is a quinone pigment found in flowering plants. | |||
T20106 |
C.I. 37558
Naphtazol OP,NSC 50681,Azotol OF |
||
C.I. 37558 is mainly used as an organic pigment intermediate. It can produce pigment red 170, pigment orange 22. | |||
T34255 | Radermachol | ||
Radermachol is a red pigment. | |||
T34448 |
Rugulosin
Radicalisin |
||
Rugulosin (RUG) is a bis-anthraquinoid pigment produced by fungi. | |||
T34534 |
Sarpedobilin
|
||
Sarpedobilin is a doubly cyclized bile pigment. It is found in butterflies. | |||
T39700 |
Ga(III) protoporphyrin IX
|
||
Ga(III)protoporphyrin-IX, a model for interporphyrin interactions in malaria pigment, possesses potent antibacterial effects against gram-negative, gram-positive, and acid-fast bacteria. It exhibits high solubility in methanol (MeOH) and serves as a malarial pigment analogue for drug development, as well as a potential antibacterial agent. | |||
T10587 | BPH-652 | Others | Others |
BPH-652 is an S. aureus dehydrosqualene synthase (CrtM) inhibitor (Ki: 1.5 nM; IC50: 100-300 nM for S. aureus pigment formation). | |||
T39569 |
Gp100 (25-33), mouse
Mgp100 (25-33),Gp100 (25-33), mouse |
||
Gp100 (25-33) corresponds to residues 25 to 33 of the mouse self/tumor antigen glycoprotein (mgp100), which is an enzyme responsible for pigment synthesis. This epitope fragment is found in both normal melanocytes and melanoma cells. | |||
T75509 | Pulcherriminic acid | ||
Pulcherriminic acid 是环状二肽抗菌剂,对Fe3+有高亲和力,主要在芽孢杆菌和酵母中发现。该化合物通过非酶促反应与铁离子螯合,生成细胞外红色素pulcherrimin,通过竞争铁营养达到抗菌效果。Pulcherriminic acid 在食品、农业和医疗等领域具有广泛应用潜力。 | |||
T81341 |
Pyr-Gly
|
||
Pyr-Gly为抑制肽类化合物,能够抑制视网膜色素上皮(RPE)细胞及成纤维细胞的增殖作用。 | |||
T82140 |
Hypertrehalosemic neuropeptide (Nauphoeta cinerea)
|
||
Hypertrehalosemic neuropeptide (Nauphoeta cinerea) 属于脂动激素/红色素浓缩激素 (AKH/RPCH) 家族,具有促进海藻糖合成的功能。 | |||
T37453 |
Butyryl-L-carnitine (chloride)
|
||
Butyryl-L-carnitine is a butyrate ester of carnitine. It is an inhibitor of intestinal transporters, blocking carnitine uptake by the carnitine transporter and glycine transport by the amino acid transporter in human retinal pigment epithelial (HRPE) cells (IC50s = 1.5 μM and 4.6 mM, respectively). | |||
T3011L |
Kynurenine sulfate monohydrate
L-Kynurenine sulfate monohydrate |
||
Kynurenine sulfate monohydrate is a precursor of kynurenic acid which is the only recognized endogenous excitatory amino acid receptor antagonist agent in the central nervous system. L-Kyn is known to be a pigment generating component in animals. In mamma | |||
T32670 |
Leucopterin
NSC 93740,NSC93740,NSC-93740,Leikopterin |
||
Leucopterin 是一种具有生物活性的蝶呤类化合物。它是芸苔蝶和其他蝴蝶翅膀中的白色色素,也可以在黄蜂和其他昆虫身上找到。 | |||
TP1120 |
Interphotoreceptor Retinoid Binding Protein Fragment (IRBP)
IRBP,Interphotoreceptor Retinoid Binding Protein Fragment IRBP |
||
Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) is a 20-residue peptide, which is a major pathogenic epitope. It exists in the first homologous repeat of interstitial visual pigment Binding Protein peptide (IRBP 161-180) and can induce post-uv | |||
T38220 |
11-cis Retinol
|
||
11-cisRetinol is an isomer of vitamin A . It is formed from vitamin A,viaatrans-retinyl ester intermediate, by the enzyme RPE65 in the retinal pigment epithelium and then converted to 11-cis retinal as part of the visual cycle.1,211-cisRetinol is an agonist of salamander and human red rod opsins expressed in COS cells and an inverse agonist of salamander red cone opsin, as well as human red and green cone opsins expressed in COS cells.3It promotes pigment formation in cone, but not rod, photorec... | |||
TP2199 |
Rhodopsin peptide
|
Others | Others |
Rhodopsin peptide is a peptide with the sequence H2N-Val-Ser-Lys-Thr-Glu-Thr-Ser-Gln-Val-Ala-Pro-Ala-OH, MW= 1217.33. Rhodopsin is a biological pigment in photoreceptor cells of the retina that is responsible for the first events in the perception of ligh | |||
T74699 | Avacincaptad pegol | ||
Avacincaptad pegol 是核酸适配体,作为 C5 补体抑制剂,用以减轻炎症导致的视网膜色素上皮 (RPE) 损伤。该化合物可用于研究 stargardt 黄斑营养不良 (STGD1) 与地理萎缩 (GA)。 | |||
T79378 |
IIIM-8
|
Melanocortin Receptor | GPCR/G Protein; Neuroscience |
IIIM-8作为一种黑色素生成抑制剂,在体外和体内均表现出显著地抑制色素生成的功效,同时对成人表皮黑色素细胞(HAEM)不表现出细胞毒性。IIIM-8适用于色素沉着症研究。 | |||
T78404 |
Pyridinium bisretinoid A2E TFA
A2E TFA |
Apoptosis | Apoptosis |
Pyridinium bisretinoid A2E TFA作为一种荧光团,能从视网膜色素上皮(RPE)的脂褐素中分离得到,是蓝光诱导的细胞凋亡(apoptosis)诱导剂。该化合物具有光活化特性,可介导自噬(autophagy)和活性氧(reactive oxygen species)的产生,常用于视网膜退行性疾病的研究。 | |||
T19884 |
CI 21100
CI21100,CI-21100 |
||
CI 21100一类有机颜料,为黄色粉末。在150℃ 加热20min 微变绿。在浓硫酸中为红光检色,稀释后呈棕光红色;在浓硝酸中为棕光黄色。主要用于橡胶、塑料制品等的着色,也用于油墨涂料等行业。 | |||
T19902 |
C.I. 15670
NSC-12453,NSC12453,NSC 12453 |
||
C.I. 15670是一种颜料,为红紫色粉末。可用于油墨、染料激光器、乙烯基聚合物制造、纺织品铁、钙、铝、钽的测定、工业水中硬度的监测、饮用水中二氧化氯的测量、降血糖剂、核荧光染料等。 | |||
T83681 |
IRBP (1-20) (human, rat) TFA
IRBP1-20,Interphotoreceptor Retinoid-Binding Protein (1-20) |
||
IRBP1-20(1-20)是IRBP的一个十二肽片段,亦称视黄醇结合蛋白3,负责运输视锥细胞中的视黄醇和视黄醛至视网膜色素上皮,参与色素再生。在携带H-2b等位基因型的C57BL/6小鼠中,IRBP1-20用于诱导自身免疫性葡萄膜视网膜炎。IRBP1-20(3 µM)能增加初级小鼠脾淋巴细胞分泌IL-4、IL-5和IL-6的水平。用IRBP1-20免疫并再次挑战,可增加IFN-γ缺乏小鼠的耳部肿胀、眼部血管炎症、免疫细胞浸润和视锥细胞层损伤,以及视网膜脱落。 | |||
TP1749 |
IRBP (1-20), human
|
||
IRBP (1-20), human is the 1-20 fragment of interphotoreceptor retinoid binding protein (IRBP).This peptide is a 1 to 20 amino acid fragment of the interphotoreceptor retinoid binding protein (IRBP). IRBP is a 140-kDa glycolipoprotein residing in the inter | |||
T20104 |
C.I. 37545
NSC 37618,Brenthol FO,Naphtanilide BG,Acna Naphthol BG,Azoic dyes |
||
C.I. 37545 is also known as Azoic dyes. C.I. 37545 is impregnated cotton with an alkaline solution of β-naphthol, then treated it with a diazo solution obtained from aniline, a toluidine, xylidine, naphthylamine, aminoazobenzene or aminoazotoluene, so tha | |||
T70977 |
JMN13497
|
||
JMN13497 is an precursor compound to for synthesis of scytonemin. Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and arrests cell cycle through downregulating Plk1 activity in many cancel cells. Scytonemin was able to inhibit the proliferation of three myeloma cells in a dose-dependent manner, while U266 was the most sensitive on... | |||
T81900 |
LVGRQLEEFL (mouse) (TFA)
|
||
LVGRQLEEFL (mouse) TFA,即G*肽,对应[113,122]apoJ中的第113至122位氨基酸序列,表现出抗炎与抗动脉粥样硬化的特性。该肽能够整合至apoJ模拟物,生成HM-10/10肽,一种新型嵌合高密度脂蛋白模拟肽。HM-10/10肽能够保护视网膜色素上皮(RPE)及光感受器,防止氧化剂引起的细胞死亡。 | |||
T70244 | JRN73958 | ||
JRN73958 is an important precursor for the synthesis of scytonemin, also called Reduced scytonemin. Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and arrests cell cycle through downregulating Plk1 activity in many cancel cells. Scytonemin was able to inhibit the proliferation of three myeloma cells in a dose-dependent manner, whi... | |||
T81901 |
LVGRQLEEFL (mouse)
|
||
LVGRQLEEFL(mouse)即G*肽,为[113,122]apoJ中113至122位氨基酸序列。该化合物展现抗炎与抗动脉粥样硬化功能。将LVGRQLEEFL(mouse)整合至apoJ模拟物,可生成HM-10/10肽,此为一种模拟肽及新型嵌合高密度脂蛋白。HM-10/10肽能守护视网膜色素上皮(RPE)及光感受器,防止氧化剂诱导下的细胞死亡。 | |||
T83700 |
IRBP (651-670) (human) TFA
IRBP651-670,Interphotoreceptor Retinoid-Binding Protein (651-670) |
||
IRBP651-670(Interphotoreceptor retinoid-binding protein (651-670))是IRBP(亦称为retinoid-binding protein 3)的肽段,参与色素再生,通过将视黄醇和视黄醛从光感受细胞传输到视网膜色素上皮。在C57BL/6小鼠中,利用IRBP651-670诱导自身免疫性葡萄膜炎,这些小鼠携带H-2b单体型。用IRBP651-670(300 µg/动物)免疫增加了小鼠眼部IL-1β、IL-6、IL-17、TNF-α和IFN-γ水平,免疫细胞浸润及光感受器损伤。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2934 |
Bilirubin
胆红素,Bilibubin,Principal bile pigment,Hematoidin,Hemetoidin |
Endogenous Metabolite | Metabolism |
Bilirubin (Principal bile pigment) 是血红素分解代谢产生的黄色产物,是肝功能的重要指标。Bilirubin 具有抗诱变和抗氧化作用。 | |||
TN1253 |
3-hydroxymorindone
|
Others | Others |
3-hydroxymorindone 是一种来自海巴戟 Morinda citrifolia 的天然产物。 3-hydroxymorindone 是一种色素。 | |||
T24729 |
Roseoflavin
|
Antibacterial | Microbiology/Virology |
Roseoflavin 是天然色素,起初分离自Streptomyces davawensis。Roseoflavin 是核黄素和黄素单核苷酸的抗代谢类似物,显示出抗菌活性。 | |||
TN6720 |
Acetylalkannin
Acetyl alkannin,Alkannin acetate |
Antibacterial | Microbiology/Virology |
Acetylalkannin (Alkannin acetate) 是一种从 Arnebia euchroma 中分离出来的异己烯基萘色素,具有抗菌和细胞毒性作用。 | |||
T4010 |
Juglone
5-羟基对萘醌,5-Hydroxy-1,4-naphthoquinone,胡桃酮,Regianin |
DNA/RNA Synthesis; Antibacterial | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Juglone (Regianin) 是一种从黑胡桃Juglans regia 中发现的黄色染料,有抗菌作用。 | |||
TN4221 |
Homoembelin
2,5-dihydroxy-3-nonyl-1,4-benzoquinone |
Antibacterial | Microbiology/Virology |
Homoembelin (2,5-dihydroxy-3-nonyl-1,4-benzoquinone) 是来自 E. ribes 和 C. monocarpus 的色素,具有抗菌效果,可用于耐多药细菌感染的研究。 | |||
T2864 |
Lycopene
番茄红素,ψ,ψ-Carotene |
Reactive Oxygen Species; ROS | Immunology/Inflammation; Metabolism; NF-κB |
Lycopene (ψ,ψ-Carotene) 是一种番茄及其产品和其他红色水果和蔬菜中天然存在的类胡萝卜素,具有抗氧化活性。 | |||
T4S2014 |
5,15-Diacetyl-3-benzoyllathyrol
,大戟因子L3,二乙酰基苯甲酰基香豌豆醇,5,15-二乙酰基-3-苯甲酰千金子二萜醇;千金二萜醇二乙酰苯甲酰酯,Euphorbia factor L3 |
Others | Others |
5,15-Diacetyl-3-benzoyllathyrol (Euphorbia factor L3) 是一种具有抗癌作用的萜类化合物。 | |||
T5852 |
Canthaxanthin
all-trans-Canthaxanthin,E 161g,角黄素,斑蝥黄 |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
Canthaxanthin (E 161g) 是具有多种生物活性的红橙色类胡萝卜素,如抗氧化、抗肿瘤活性。它属于叶黄素组,是存在于细菌、藻类和一些真菌中的天然色素。 | |||
T19224 |
C-Phycocyanin
C-PC,藻蓝蛋白,C-藻蓝蛋白 |
Others | Others |
C-Phycocyanin (C-PC) 是一种蛋白质色素,常作为人类的优良营养补充剂。 | |||
T5311 |
Crocin (Gardenia Fruits Extract)
藏红花,西红花苷 |
Others | Others |
Crocin (Gardenia Fruits Extract)(42553-65-1)是藏红花(Crocus sativus L.)的水溶性类胡萝卜素色素。藏红花素具有抗炎、抗氧化、抗凋亡、抗哮喘、抗癌、降血脂等作用。 | |||
T2897 |
(Rac)-Shikonin
(±)-Shikonin,Alkanet extract,Anchusin,紫草素,Anchusa acid |
Others | Others |
(Rac)-Shikonin (Anchusin) 具有抗肿瘤作用。它能够诱导坏死死亡来绕过癌症耐药性。 | |||
T7600 |
Fucoxanthin
all-trans-Fucoxanthin |
Others | Others |
Fucoxanthin (all-trans-Fucoxanthin) 是海洋类胡萝卜素,具有抗肥胖,抗糖尿病,抗炎,抗氧化,抗癌等作用。 | |||
T4958 |
(-)-Alkannin
Alkannin,左旋紫草素,紫草素,Shikonin |
Apoptosis; PI3K | Apoptosis; PI3K/Akt/mTOR signaling |
(-)-Alkannin (Shikonin) 是从紫朱草中发现的一种天然产物,具有抗癌活性,可抑制细胞周期,诱导细胞凋亡,用作食品着色剂,在 Rho 激酶途径中可改善肝脏炎症。 | |||
T2823 |
Crocin
西红花苷,藏红花,Gardenia Yellow,Alpha-Crocin,藏红花素 |
Others | Others |
Crocin (Gardenia Yellow) 是从Crocus sativus 柱头中分离出的主要成分,是一种营养保健品,具有抗炎,抗癌,抗抑郁和抗惊厥等强大的药理作用。 | |||
TN1567 |
Delphinidin chloride
|
Estrogen Receptor/ERR; VEGFR | Angiogenesis; Endocrinology/Hormones; Tyrosine Kinase/Adaptors |
Delphinidin chloride 是一种花青素,是一种可从浆果和红酒中分离得到的天然植物色素,是某些花青素的前体。Delphinidin chloride 诱导血管内皮释放一氧化氮,引起血管松弛。在1 ~ 40 μM 剂量下,对上皮生长因子受体的信号传导和雌激素受体α的表达有抑制作用,与细胞凋亡和自噬有关。Delphinidin chloride 能调节 JAK/STAT3 和 MAPKinase 信号传导。Delphinidin 还能抑制 p300/CBP 的组蛋白乙酰转移酶活性(IC50 在约为30 μM) | |||
T4858 |
4-Hydroxyphenylpyruvic acid
4-羟苯基丙酮酸,4-Hydroxyphenylpyruvic acid |
Endogenous Metabolite | Metabolism |
4-Hydroxyphenylpyruvic acid 是一种苯丙氨酸代谢的中间产物,是一种酶抑制剂。 | |||
T34442 |
Rubrofusarin
|
||
Rubrofusarin is an orange polyketide pigment. | |||
T26810 |
Bikaverin
BRN 0358013,Lycopersin |
||
Bikaverin is a reddish pigment produced by different fungal species with antibiotic properties against certain protozoa and fungi. Bikaverin also has antitumoral activity against different cancer cell lines. | |||
T26167 |
Rubropunctatin
Rubropunctamine |
||
Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects. | |||
T32799 |
Lithospermidin B
|
||
Lithospermidin B is a minor pigment isolated from the roots of L. erythrorhizon. | |||
T81507 |
Petunidin 3-rutinoside
|
||
Petunidin 3-rutinoside,一种可从Sambucus canadensis分离的天然产物。 | |||
T40643 |
Prodigiosin hydrochloride
盐酸灵菌红素,Prodigiosine hydrochloride |
||
Prodigiosin hydrochloride, a red pigment, is a bioactive secondary metabolite produced by bacteria. It exhibits potent proapoptotic activity and functions as an inhibitor of the Wnt/β-catenin pathway. Additionally, this compound possesses antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties. | |||
T82926 | Bacteriopheophytin | ||
Bacteriopheophytin是细菌脱镁叶绿素的一种,由细菌叶绿素去除镁中心并由两个氢原子取代形成。在紫色细菌的反应中心(RC)中,它作为电子受体参与电子转移过程。 | |||
T75608 | Myricetin 3-O-α-L-arabinopyranoside | ||
Myricetin 3-O-α-L-arabinopyranoside 抑制 A2E 光氧化诱导的RPE 细胞死亡。Myricetin 3-O-α-L-arabinopyranoside 对视网膜变性具有保护作用,可保护蓝光 (BL) 诱导对 RPE 细胞和小鼠模型的损伤。 | |||
T79996 |
N,N′-Diferuloylputrescine
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Melanocortin Receptor | GPCR/G Protein; Neuroscience |
N,N′-Diferuloylputrescine 作为pigmentation的抑制剂,有效减少了57%的色素沉着,并显著降低了MITF蛋白水平。同时,该化合物对活性氧表现出强大的抗氧化活性。 | |||
TN1886 |
Lucidin primeveroside
Lucidin 3-O-primeveroside,亮黄素3-桑色素酊 |
Topoisomerase | DNA Damage/DNA Repair |
Lucidin primeveroside (Lucidin 3-O-primeveroside) 是从茜草的根粉中分离得到的天然产物,可用作着色剂和食用色素。 Lucidin Primeveroside 可以在小鼠体内代谢转化为基因毒性化合物 Lucidin。 | |||
T70495 | Scytonemin | ||
Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and arrests cell cycle through downregulating Plk1 activity in many cancel cells. Scytonemin was able to inhibit the proliferation of three myeloma cells in a dose-dependent manner, while U266 was the most sensitive one to scytonemin. Scytonemin , representing a novel Plk1 inhibitor, ... | |||
T35751 |
Violacein
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Violacein is a bacterial metabolite originally isolated from C. violaceum that has antibacterial and antiprotozoal activities.[1] [2] It is produced by C. violaceum as a purple pigment in response to N-hexanoyl homoserine lactone , a property that has been modified to create a strain of C. violaceum used in detecting quorum-sensing molecules.[3] Violacein is active against Gram-positive bacteria, including B. subtilis and S. aureus (MICs = 0.8 and 1.6 µM, respectively). It is also active aga... |